Works by Hewitt, Alex W.

Results: 157
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    Mitochondrial haplogroups are not associated with diabetic retinopathy in a large Australian and British Caucasian sample.

    Published in:
    Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-018-37388-8
    By:
    • Liu, Ebony;
    • Kaidonis, Georgia;
    • Gillies, Mark C.;
    • Abhary, Sotoodeh;
    • Essex, Rohan W.;
    • Chang, John H.;
    • Pal, Bishwanath;
    • Daniell, Mark;
    • Lake, Stewart;
    • Gilhotra, Jolly;
    • Petrovsky, Nikolai;
    • Hewitt, Alex W.;
    • Jenkins, Alicia;
    • Lamoureux, Ecosse L.;
    • Gleadle, Jonathan M.;
    • Burdon, Kathryn P.;
    • Craig, Jamie E.
    Publication type:
    Article
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    Single cell eQTL analysis identifies cell type-specific genetic control of gene expression in fibroblasts and reprogrammed induced pluripotent stem cells.

    Published in:
    Genome Biology, 2021, v. 22, n. 1, p. 1, doi. 10.1186/s13059-021-02293-3
    By:
    • Neavin, Drew;
    • Nguyen, Quan;
    • Daniszewski, Maciej S.;
    • Liang, Helena H.;
    • Chiu, Han Sheng;
    • Wee, Yong Kiat;
    • Senabouth, Anne;
    • Lukowski, Samuel W.;
    • Crombie, Duncan E.;
    • Lidgerwood, Grace E.;
    • Hernández, Damián;
    • Vickers, James C.;
    • Cook, Anthony L.;
    • Palpant, Nathan J.;
    • Pébay, Alice;
    • Hewitt, Alex W.;
    • Powell, Joseph E.
    Publication type:
    Article
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    Longitudinal expression profiling of CD4+ and CD8+ cells in patients with active to quiescent giant cell arteritis.

    Published in:
    BMC Medical Genomics, 2018, v. 11, n. 1, p. N.PAG, doi. 10.1186/s12920-018-0376-4
    By:
    • De Smit, Elisabeth;
    • Lukowski, Samuel W.;
    • Anderson, Lisa;
    • Senabouth, Anne;
    • Dauyey, Kaisar;
    • Song, Sharon;
    • Wyse, Bruce;
    • Wheeler, Lawrie;
    • Chen, Christine Y.;
    • Cao, Khoa;
    • Wong Ten Yuen, Amy;
    • Shuey, Neil;
    • Clarke, Linda;
    • Lopez Sanchez, Isabel;
    • Hung, Sandy S. C.;
    • Pébay, Alice;
    • Mackey, David A.;
    • Brown, Matthew A.;
    • Hewitt, Alex W.;
    • Powell, Joseph E.
    Publication type:
    Article
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    Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.

    Published in:
    Nature Genetics, 2013, v. 45, n. 6, p. 712, doi. 10.1038/ng0613-712b
    By:
    • Verhoeven, Virginie J M;
    • Hysi, Pirro G;
    • Wojciechowski, Robert;
    • Fan, Qiao;
    • Guggenheim, Jeremy A;
    • Höhn, René;
    • MacGregor, Stuart;
    • Hewitt, Alex W;
    • Nag, Abhishek;
    • Cheng, Ching-Yu;
    • Yonova-Doing, Ekaterina;
    • Zhou, Xin;
    • Ikram, M Kamran;
    • Buitendijk, Gabriëlle H S;
    • McMahon, George;
    • Kemp, John P;
    • Pourcain, Beate St;
    • Simpson, Claire L;
    • Mäkelä, Kari-Matti;
    • Lehtimäki, Terho
    Publication type:
    Article
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    Genome-wide meta-analyses of multiancestry cohorts identify multiple new susceptibility loci for refractive error and myopia.

    Published in:
    Nature Genetics, 2013, v. 45, n. 3, p. 314, doi. 10.1038/ng.2554
    By:
    • Verhoeven, Virginie J M;
    • Hysi, Pirro G;
    • Wojciechowski, Robert;
    • Fan, Qiao;
    • Guggenheim, Jeremy A;
    • Höhn, René;
    • MacGregor, Stuart;
    • Hewitt, Alex W;
    • Nag, Abhishek;
    • Cheng, Ching-Yu;
    • Yonova-Doing, Ekaterina;
    • Zhou, Xin;
    • Ikram, M Kamran;
    • Buitendijk, Gabriëlle H S;
    • McMahon, George;
    • Kemp, John P;
    • Pourcain, Beate St;
    • Simpson, Claire L;
    • Mäkelä, Kari-Matti;
    • Lehtimäki, Terho
    Publication type:
    Article
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    Genome-wide association analyses identify multiple loci associated with central corneal thickness and keratoconus.

    Published in:
    Nature Genetics, 2013, v. 45, n. 2, p. 155, doi. 10.1038/ng.2506
    By:
    • Lu, Yi;
    • Vitart, Veronique;
    • Burdon, Kathryn P;
    • Khor, Chiea Chuen;
    • Bykhovskaya, Yelena;
    • Mirshahi, Alireza;
    • Hewitt, Alex W;
    • Koehn, Demelza;
    • Hysi, Pirro G;
    • Ramdas, Wishal D;
    • Zeller, Tanja;
    • Vithana, Eranga N;
    • Cornes, Belinda K;
    • Tay, Wan-Ting;
    • Tai, E Shyong;
    • Cheng, Ching-Yu;
    • Liu, Jianjun;
    • Foo, Jia-Nee;
    • Saw, Seang Mei;
    • Thorleifsson, Gudmar
    Publication type:
    Article
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    Genome-wide association study identifies susceptibility loci for open angle glaucoma at TMCO1 and CDKN2B-AS1.

    Published in:
    Nature Genetics, 2011, v. 43, n. 6, p. 574, doi. 10.1038/ng.824
    By:
    • Burdon, Kathryn P.;
    • Macgregor, Stuart;
    • Hewitt, Alex W.;
    • Sharma, Shiwani;
    • Chidlow, Glyn;
    • Mills, Richard A.;
    • Danoy, Patrick;
    • Casson, Robert;
    • Viswanathan, Ananth C.;
    • Liu, Jimmy Z.;
    • Landers, John;
    • Henders, Anjali K.;
    • Wood, John;
    • Souzeau, Emmanuelle;
    • Crawford, April;
    • Leo, Paul;
    • Jie Jin Wang;
    • Rochtchina, Elena;
    • Nyholt, Dale R.;
    • Martin, Nicholas G.
    Publication type:
    Article
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    Common variants near CAV1 and CAV2 are associated with primary open-angle glaucoma.

    Published in:
    Nature Genetics, 2010, v. 42, n. 10, p. 906, doi. 10.1038/ng.661
    By:
    • Thorleifsson, Gudmar;
    • Walters, G. Bragi;
    • Hewitt, Alex W.;
    • Masson, Gisli;
    • Helgason, Agnar;
    • DeWan, Andrew;
    • Sigurdsson, Asgeir;
    • Jonasdottir, Adalbjorg;
    • Gudjonsson, Sigurjon A.;
    • Magnusson, Kristinn P.;
    • Stefansson, Hreinn;
    • Lam, Dennis S. C.;
    • Tam, Pancy O. S.;
    • Gudmundsdottir, Gudrun J.;
    • Southgate, Laura;
    • Burdon, Kathryn P.;
    • Gottfredsdottir, Maria Soffia;
    • Aldred, Micheala A.;
    • Mitchell, Paul;
    • Clair, David St.
    Publication type:
    Article
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    A genome-wide association study for myopia and refractive error identifies a susceptibility locus at 15q25.

    Published in:
    Nature Genetics, 2010, v. 42, n. 10, p. 902, doi. 10.1038/ng.664
    By:
    • Hysi, Pirro G.;
    • Young, Terri L.;
    • Mackey, David A.;
    • Andrew, Toby;
    • Fernández-Medarde, Alberto;
    • Solouki, Abbas M.;
    • Hewitt, Alex W.;
    • Macgregor, Stuart;
    • Vingerling, Johannes R.;
    • Yi-Ju Li;
    • Ikram, M. Kamran;
    • Lee Yiu Fai;
    • Sham, Pak C.;
    • Manyes, Lara;
    • Porteros, Angel;
    • Lopes, Margarida C.;
    • Carbonaro, Francis;
    • Fahy, Samantha J.;
    • Martin, Nicholas G.;
    • van Duijn, Cornelia M.
    Publication type:
    Article
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    Multi-trait genome-wide association study identifies new loci associated with optic disc parameters.

    Published in:
    Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0634-9
    By:
    • Bonnemaijer, Pieter W. M.;
    • Leeuwen, Elisabeth M. van;
    • Iglesias, Adriana I.;
    • Gharahkhani, Puya;
    • Vitart, Veronique;
    • Khawaja, Anthony P.;
    • Simcoe, Mark;
    • Höhn, René;
    • Cree, Angela J.;
    • Igo, Rob P.;
    • International Glaucoma Genetics Consortium;
    • Burdon, Kathryn P.;
    • Craig, Jamie E.;
    • Hewitt, Alex W.;
    • Jonas, Jost;
    • Khor, Chiea-Cheun;
    • Pasutto, Francesca;
    • Mackey, David A.;
    • Mitchell, Paul;
    • Mishra, Aniket
    Publication type:
    Article
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    Genetic Dissection of Acute Anterior Uveitis Reveals Similarities and Differences in Associations Observed With Ankylosing Spondylitis.

    Published in:
    Arthritis & Rheumatology, 2015, v. 67, n. 1, p. 140, doi. 10.1002/art.38873
    By:
    • Robinson, Philip C.;
    • Claushuis, Theodora A. M.;
    • Cortes, Adrian;
    • Martin, Tammy M.;
    • Evans, David M.;
    • Leo, Paul;
    • Mukhopadhyay, Pamela;
    • Bradbury, Linda A.;
    • Cremin, Katie;
    • Harris, Jessica;
    • Maksymowych, Walter P.;
    • Inman, Robert D.;
    • Rahman, Proton;
    • Haroon, Nigil;
    • Gensler, Lianne;
    • Powell, Joseph E.;
    • Horst‐Bruinsma, Irene E.;
    • Hewitt, Alex W.;
    • Craig, Jamie E.;
    • Lim, Lyndell L.
    Publication type:
    Article
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    A Simple Differentiation Protocol for Generation of Induced Pluripotent Stem Cell-Derived Basal Forebrain-Like Cholinergic Neurons for Alzheimer's Disease and Frontotemporal Dementia Disease Modeling.

    Published in:
    Cells (2073-4409), 2020, v. 9, n. 9, p. 2018, doi. 10.3390/cells9092018
    By:
    • Muñoz, Sonia Sanz;
    • Engel, Martin;
    • Balez, Rachelle;
    • Do-Ha, Dzung;
    • Cabral-da-Silva, Mauricio Castro;
    • Hernández, Damian;
    • Berg, Tracey;
    • Fifita, Jennifer A.;
    • Grima, Natalie;
    • Yang, Shu;
    • Blair, Ian P.;
    • Nicholson, Garth;
    • Cook, Anthony L.;
    • Hewitt, Alex W.;
    • Pébay, Alice;
    • Ooi, Lezanne
    Publication type:
    Article
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    Heritability of Strabismus: Genetic Influence Is Specific to Eso-Deviation and Independent of Refractive Error.

    Published in:
    Twin Research & Human Genetics, 2012, v. 15, n. 5, p. 624, doi. 10.1017/thg.2012.22
    By:
    • Sanfilippo, Paul G.;
    • Hammond, Christopher J.;
    • Staffieri, Sandra E.;
    • Kearns, Lisa S.;
    • Melissa Liew, S. H.;
    • Barbour, Julie M.;
    • Hewitt, Alex W.;
    • Ge, Dongliang;
    • Snieder, Harold;
    • MacKinnon, Jane R.;
    • Brown, Shayne A.;
    • Lorenz, Birgit;
    • Spector, Tim D.;
    • Martin, Nicholas G.;
    • Wilmer, Jeremy B.;
    • Mackey, David A.
    Publication type:
    Article
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    Genome-Wide Association Study of Retinopathy in Individuals without Diabetes.

    Published in:
    PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0054232
    By:
    • Jensen, Richard A.;
    • Sim, Xueling;
    • Li, Xiaohui;
    • Cotch, Mary Frances;
    • Ikram, M. Kamran;
    • Holliday, Elizabeth G.;
    • Eiriksdottir, Gudny;
    • Harris, Tamara B.;
    • Jonasson, Fridbert;
    • Klein, Barbara E. K.;
    • Launer, Lenore J.;
    • Smith, Albert Vernon;
    • Boerwinkle, Eric;
    • Cheung, Ning;
    • Hewitt, Alex W.;
    • Liew, Gerald;
    • Mitchell, Paul;
    • Wang, Jie Jin;
    • Attia, John;
    • Scott, Rodney
    Publication type:
    Article
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    Insights into the Genetic Architecture of Early Stage Age-Related Macular Degeneration: A Genome-Wide Association Study Meta-Analysis.

    Published in:
    PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0053830
    By:
    • Holliday, Elizabeth G.;
    • Smith, Albert V.;
    • Cornes, Belinda K.;
    • Buitendijk, Gabriëlle H. S.;
    • Jensen, Richard A.;
    • Xueling Sim;
    • Aspelund, Thor;
    • Tin Aung;
    • Baird, Paul N.;
    • Boerwinkle, Eric;
    • Ching Yu Cheng;
    • van Duijn, Cornelia M.;
    • Eiriksdottir, Gudny;
    • Gudnason, Vilmundur;
    • Harris, Tamara;
    • Hewitt, Alex W.;
    • Inouye, Michael;
    • Jonasson, Fridbert;
    • Klein, Barbara E. K.;
    • Launer, Lenore
    Publication type:
    Article
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    A single‐cell transcriptome atlas of the adult human retina.

    Published in:
    EMBO Journal, 2019, v. 38, n. 18, p. N.PAG, doi. 10.15252/embj.2018100811
    By:
    • Lukowski, Samuel W;
    • Lo, Camden Y;
    • Sharov, Alexei A;
    • Nguyen, Quan;
    • Fang, Lyujie;
    • Hung, Sandy SC;
    • Zhu, Ling;
    • Zhang, Ting;
    • Grünert, Ulrike;
    • Nguyen, Tu;
    • Senabouth, Anne;
    • Jabbari, Jafar S;
    • Welby, Emily;
    • Sowden, Jane C;
    • Waugh, Hayley S;
    • Mackey, Adrienne;
    • Pollock, Graeme;
    • Lamb, Trevor D;
    • Wang, Peng‐Yuan;
    • Hewitt, Alex W
    Publication type:
    Article
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    Genetic variation affects morphological retinal phenotypes extracted from UK Biobank optical coherence tomography images.

    Published in:
    PLoS Genetics, 2021, v. 17, n. 5, p. 1, doi. 10.1371/journal.pgen.1009497
    By:
    • Currant, Hannah;
    • Hysi, Pirro;
    • Fitzgerald, Tomas W.;
    • Gharahkhani, Puya;
    • Bonnemaijer, Pieter W. M.;
    • Senabouth, Anne;
    • Hewitt, Alex W.;
    • Atan, Denize;
    • Aung, Tin;
    • Charng, Jason;
    • Choquet, Hélène;
    • Craig, Jamie;
    • Khaw, Peng T.;
    • Klaver, Caroline C. W.;
    • Kubo, Michiaki;
    • Ong, Jue-Sheng;
    • Pasquale, Louis R.;
    • Reisman, Charles A.;
    • Daniszewski, Maciej;
    • Powell, Joseph E.
    Publication type:
    Article
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    Genetic Isolates in Ophthalmic Diseases.

    Published in:
    Ophthalmic Genetics, 2008, v. 29, n. 4, p. 149, doi. 10.1080/13816810802334341
    By:
    • Sherwin, Justin C.;
    • Hewitt, Alex W.;
    • Ruddle, Jonathan B.;
    • Mackey, David A.
    Publication type:
    Article
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    PAX6 Mutations May Be Associated with High Myopia.

    Published in:
    Ophthalmic Genetics, 2007, v. 28, n. 3, p. 179, doi. 10.1080/13816810701356676
    By:
    • Hewitt, Alex W.;
    • Kearns, Lisa S.;
    • Jamieson, Robyn V.;
    • Williamson, Kathy A.;
    • van Heyningen, Veronica;
    • Mackey, David A.
    Publication type:
    Article
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