Works by Hesselink, Matthijs K. C.

Results: 72
    1

    Carnitine supplementation improves insulin sensitivity and skeletal muscle acetylcarnitine formation in patients with type 2 diabetes.

    Published in:
    Diabetes, Obesity & Metabolism, 2025, v. 27, n. 5, p. 2864, doi. 10.1111/dom.16298
    By:
    • Op den Kamp‐Bruls, Yvonne M. H.;
    • Op den Kamp, Yvo J. M.;
    • Veeraiah, Pandichelvam;
    • Zapata Perez, Ruben;
    • Phielix, Esther;
    • Havekes, Bas;
    • Schaart, Gert;
    • Kornips, Esther;
    • Berendsen, Bart R. B.;
    • Virmani, Ashraf;
    • Wildberger, Joachim E.;
    • Houtkooper, Riekelt H.;
    • Hesselink, Matthijs K. C.;
    • Schrauwen, Patrick;
    • Schrauwen‐Hinderling, Vera B.
    Publication type:
    Article
    2

    Development of a <sup>31</sup>P magnetic resonance spectroscopy technique to quantify NADH and NAD<sup>+</sup> at 3 T.

    Published in:
    Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-53292-4
    By:
    • Mevenkamp, Julian;
    • Bruls, Yvonne M. H.;
    • Mancilla, Rodrigo;
    • Grevendonk, Lotte;
    • Wildberger, Joachim E.;
    • Brouwers, Kim;
    • Hesselink, Matthijs K. C.;
    • Schrauwen, Patrick;
    • Hoeks, Joris;
    • Houtkooper, Riekelt H.;
    • Buitinga, Mijke;
    • de Graaf, Robin A.;
    • Lindeboom, Lucas;
    • Schrauwen-Hinderling, Vera B.
    Publication type:
    Article
    3

    Circadian misalignment disturbs the skeletal muscle lipidome in healthy young men.

    Published in:
    FASEB Journal, 2021, v. 35, n. 6, p. 1, doi. 10.1096/fj.202100143R
    By:
    • Harmsen, Jan-Frieder;
    • van Polanen, Nynke;
    • van Weeghel, Michel;
    • Wefers, Jakob;
    • Hoeks, Joris;
    • Vaz, Frédéric M.;
    • Pras-Raves, Mia L.;
    • van Kampen, Antoine H. C.;
    • Schaart, Gert;
    • van Moorsel, Dirk;
    • Hansen, Jan;
    • Hesselink, Matthijs K. C.;
    • Houtkooper, Riekelt H.;
    • Schrauwen, Patrick
    Publication type:
    Article
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    Long-echo time MR spectroscopy for skeletal muscle acetylcarnitine detection.

    Published in:
    Journal of Clinical Investigation, 2014, v. 124, n. 11, p. 4915, doi. 10.1172/JCI74830
    By:
    • Lindeboom, Lucas;
    • Nabuurs, Christine I.;
    • Hoeks, Joris;
    • Brouwers, Bram;
    • Phielix, Esther;
    • Kooi, M. Eline;
    • Hesselink, Matthijs K. C.;
    • Wildberger, Joachim E.;
    • Stevens, Robert D.;
    • Koves, Timothy;
    • Muoio, Deborah M.;
    • Schrauwen, Patrick;
    • Schrauwen-Hinderling, Vera B.
    Publication type:
    Article
    10

    The tissue‐specific metabolic effects of the PPARα agonist ciprofibrate in insulin‐resistant male individuals: a double‐blind, randomized, placebo‐controlled crossover study.

    Published in:
    Obesity (19307381), 2023, v. 31, n. 10, p. 2493, doi. 10.1002/oby.23874
    By:
    • de Wit‐Verheggen, Vera H. W.;
    • Vanweert, Froukje;
    • Raiko, Juho;
    • Liénard, Viktor;
    • Schaart, Gert;
    • Gemmink, Anne;
    • Nascimento, Emmani B. M.;
    • Hesselink, Matthijs K. C.;
    • Wildberger, Joachim E.;
    • Wierts, Roel;
    • Joris, Peter J.;
    • Haas, Joel;
    • Montaigne, David;
    • Staels, Bart;
    • Phielix, Esther;
    • Schrauwen, Patrick;
    • Schrauwen‐Hinderling, Vera B.;
    • van de Weijer, Tineke
    Publication type:
    Article
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    Benefits of Substituting Sitting with Standing and Walking in Free-Living Conditions for Cardiometabolic Risk Markers, Cognition and Mood in Overweight Adults.

    Published in:
    Frontiers in Physiology, 2017, p. 1, doi. 10.3389/fphys.2017.00353
    By:
    • Duvivier, M. F. M. Bernard;
    • Schaper, C. Nicolaas;
    • Koster, Annemarie;
    • van Kan, Linh;
    • Harry Peters, P. F.;
    • Adam, J. Jos;
    • Giesbrecht, Timo;
    • Kornips, Esther;
    • Hulsbosch, Martine;
    • Willems, Paul;
    • Hesselink, K. C. Matthijs;
    • Schrauwen, Patrick;
    • Savelberg, H. C. M. Hans
    Publication type:
    Article
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    Skeletal Muscle Lipase Content and Activity in Obesity and Type 2 Diabetes.

    Published in:
    Journal of Clinical Endocrinology & Metabolism, 2010, v. 95, n. 12, p. 5449, doi. 10.1210/jc.2010-0776
    By:
    • Jocken, Johan W. E.;
    • Moro, Cedric;
    • Goossens, Gijs H.;
    • Hansen, Dominique;
    • Mairal, Aline;
    • Hesselink, Matthijs K. C.;
    • Langin, Dominique;
    • van Loon, Luc J. C.;
    • Blaak, Ellen E.
    Publication type:
    Article
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    Sitting less elicits metabolic responses similar to exercise and enhances insulin sensitivity in postmenopausal women.

    Published in:
    Diabetologia, 2021, v. 64, n. 12, p. 2817, doi. 10.1007/s00125-021-05558-5
    By:
    • Remie, Carlijn M. E.;
    • Janssens, Georges E.;
    • Bilet, Lena;
    • van Weeghel, Michel;
    • Duvivier, Bernard M. F. M.;
    • de Wit, Vera H. W.;
    • Connell, Niels J.;
    • Jörgensen, Johanna A.;
    • Schomakers, Bauke V.;
    • Schrauwen-Hinderling, Vera B.;
    • Hoeks, Joris;
    • Hesselink, Matthijs K. C.;
    • Phielix, Esther;
    • Houtkooper, Riekelt H.;
    • Schrauwen, Patrick
    Publication type:
    Article
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    One-leg inactivity induces a reduction in mitochondrial oxidative capacity, intramyocellular lipid accumulation and reduced insulin signalling upon lipid infusion: a human study with unilateral limb suspension.

    Published in:
    Diabetologia, 2020, v. 63, n. 6, p. 1211, doi. 10.1007/s00125-020-05128-1
    By:
    • Bilet, Lena;
    • Phielix, Esther;
    • van de Weijer, Tineke;
    • Gemmink, Anne;
    • Bosma, Madeleen;
    • Moonen-Kornips, Esther;
    • Jorgensen, Johanna A.;
    • Schaart, Gert;
    • Zhang, Dongyan;
    • Meijer, Kenneth;
    • Hopman, Maria;
    • Hesselink, Matthijs K. C.;
    • Ouwens, D. Margriet;
    • Shulman, Gerald I.;
    • Schrauwen-Hinderling, Vera B.;
    • Schrauwen, Patrick
    Publication type:
    Article
    35

    Understanding heterogeneity of responses to, and optimizing clinical efficacy of, exercise training in older adults: NIH NIA Workshop summary.

    Published in:
    GeroScience, 2023, v. 45, n. 1, p. 569, doi. 10.1007/s11357-022-00668-3
    By:
    • Erickson, Melissa L.;
    • Allen, Jacob M.;
    • Beavers, Daniel P.;
    • Collins, Linda M.;
    • Davidson, Karina W.;
    • Erickson, Kirk I.;
    • Esser, Karyn A.;
    • Hesselink, Matthijs K. C.;
    • Moreau, Kerrie L.;
    • Laber, Eric B.;
    • Peterson, Charlotte A.;
    • Peterson, Courtney M.;
    • Reusch, Jane E.;
    • Thyfault, John P.;
    • Youngstedt, Shawn D.;
    • Zierath, Juleen R.;
    • Goodpaster, Bret H.;
    • LeBrasseur, Nathan K.;
    • Buford, Thomas W.;
    • Sparks, Lauren M.
    Publication type:
    Article
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    What are the benefits of being big?

    Published in:
    Journal of Physiology, 2017, v. 595, n. 16, p. 5409, doi. 10.1113/JP274723
    By:
    • Hesselink, Matthijs K. C.;
    • Daemen, Sabine;
    • Polanen, Nynke;
    • Gemmink, Anne
    Publication type:
    Article
    38

    Empagliflozin prevents heart failure through inhibition of the NHE1-NO pathway, independent of SGLT2.

    Published in:
    Basic Research in Cardiology, 2024, v. 119, n. 5, p. 751, doi. 10.1007/s00395-024-01067-9
    By:
    • Chen, Sha;
    • Wang, Qian;
    • Bakker, Diane;
    • Hu, Xin;
    • Zhang, Liping;
    • van der Made, Ingeborg;
    • Tebbens, Anna M.;
    • Kovácsházi, Csenger;
    • Giricz, Zoltán;
    • Brenner, Gábor B.;
    • Ferdinandy, Peter;
    • Schaart, Gert;
    • Gemmink, Anne;
    • Hesselink, Matthijs K. C.;
    • Rivaud, Mathilde R.;
    • Pieper, Michael P.;
    • Hollmann, Markus W.;
    • Weber, Nina C.;
    • Balligand, Jean-Luc;
    • Creemers, Esther E.
    Publication type:
    Article
    39

    Lack of UCP3 does not affect skeletal muscle mitochondrial function under lipid-challenged conditions, but leads to sudden cardiac death.

    Published in:
    Basic Research in Cardiology, 2014, v. 109, n. 1, p. 1, doi. 10.1007/s00395-014-0447-4
    By:
    • Nabben, Miranda;
    • van Bree, Bianca W. J.;
    • Lenaers, Ellen;
    • Hoeks, Joris;
    • Hesselink, Matthijs K. C.;
    • Schaart, Gert;
    • Gijbels, Marion J. J.;
    • Glatz, Jan F. C.;
    • da Silva, Gustavo J. J.;
    • de Windt, Leon J.;
    • Tian, Rong;
    • Mike, Elise;
    • Skapura, Darlene G.;
    • Wehrens, Xander H. T.;
    • Schrauwen, Patrick
    Publication type:
    Article
    40

    PCr/ATP ratios and mitochondrial function in the heart. A comparative study in humans.

    Published in:
    Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-35041-7
    By:
    • de Wit-Verheggen, Vera H. W.;
    • Schrauwen-Hinderling, Vera B.;
    • Brouwers, Kim;
    • Jörgensen, Johanna A.;
    • Schaart, Gert;
    • Gemmink, Anne;
    • Nascimento, Emmani B. M.;
    • Hesselink, Matthijs K. C.;
    • Wildberger, Joachim E.;
    • Segers, Patrique;
    • Montaigne, David;
    • Staels, Bart;
    • Schrauwen, Patrick;
    • Lindeboom, Lucas;
    • Hoeks, Joris;
    • van de Weijer, Tineke
    Publication type:
    Article
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    Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy.

    Published in:
    Nature Medicine, 2013, v. 19, n. 8, p. 1039, doi. 10.1038/nm.3213
    By:
    • Woldt, Estelle;
    • Sebti, Yasmine;
    • Solt, Laura A;
    • Duhem, Christian;
    • Lancel, Steve;
    • Eeckhoute, Jérôme;
    • Hesselink, Matthijs K C;
    • Paquet, Charlotte;
    • Delhaye, Stéphane;
    • Shin, Youseung;
    • Kamenecka, Theodore M;
    • Schaart, Gert;
    • Lefebvre, Philippe;
    • Nevière, Rémi;
    • Burris, Thomas P;
    • Schrauwen, Patrick;
    • Staels, Bart;
    • Duez, Hélène
    Publication type:
    Article
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    Uncoupling protein 3 as a mitochondrial fatty acid anion exporter.

    Published in:
    FASEB Journal, 2003, v. 17, n. 15, p. 2272, doi. 10.1096/fj.03-0515fje
    By:
    • Schrauwen, Patrick;
    • Hoeks, Joris;
    • Schaart, Gert;
    • Kornips, Esther;
    • Binas, Bert;
    • Van de Vusse, Ger J;
    • Van Bilsen, Marc;
    • Luiken, Joost J. F. P.;
    • Coort, Susan L. M.;
    • Glatz, Jan F. C.;
    • Saris, Wim H. M.;
    • Hesselink, Matthijs K. C.
    Publication type:
    Article
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    Evidence for a direct effect of the NAD+ precursor acipimox on muscle mitochondrial function in humans.

    Published in:
    2015
    By:
    • van de Weijer, Tineke;
    • Phielix, Esther;
    • Bilet, Lena;
    • Williams, Evan G;
    • Ropelle, Eduardo R;
    • Bierwagen, Alessandra;
    • Livingstone, Roshan;
    • Nowotny, Peter;
    • Sparks, Lauren M;
    • Paglialunga, Sabina;
    • Szendroedi, Julia;
    • Havekes, Bas;
    • Moullan, Norman;
    • Pirinen, Eija;
    • Hwang, Jong-Hee;
    • Schrauwen-Hinderling, Vera B;
    • Hesselink, Matthijs K C;
    • Auwerx, Johan;
    • Roden, Michael;
    • Schrauwen, Patrick
    Publication type:
    journal article
    47

    Evidence for a Direct Effect of the NAD<sup>+</sup> Precursor Acipimox on Muscle Mitochondrial Function in Humans.

    Published in:
    Diabetes, 2015, v. 64, n. 4, p. 1193, doi. 10.2337/db14-0667
    By:
    • van de Weijer, Tineke;
    • Phielix, Esther;
    • Bilet, Lena;
    • Williams, Evan G.;
    • Ropelle, Eduardo R.;
    • Bierwagen, Alessandra;
    • Livingstone, Roshan;
    • Nowotny, Peter;
    • Sparks, Lauren M.;
    • Paglialunga, Sabina;
    • Szendroedi, Julia;
    • Havekes, Bas;
    • Moullan, Norman;
    • Pirinen, Eija;
    • Jong-Hee Hwang;
    • Schrauwen-Hinderling, Vera B.;
    • Hesselink, Matthijs K. C.;
    • Auwerx, Johan;
    • Roden, Michael;
    • Schrauwen, Patrick
    Publication type:
    Article
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    Blocking the Entrance to Open the Gate.

    Published in:
    Diabetes, 2013, v. 62, n. 3, p. 703, doi. 10.2337/db12-1663
    By:
    • Schrauwen, Patrick;
    • Timmers, Silvie;
    • Hesselink, Matthijs K. C.
    Publication type:
    Article
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