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A targetable 'rogue' neutrophil-subset, [CD11b+DEspR+] immunotype, is associated with severity and mortality in acute respiratory distress syndrome (ARDS) and COVID-19-ARDS.
Published in:
Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-09343-1
By:
- Herrera, Victoria L. M.;
- Walkey, Allan J.;
- Nguyen, Mai Q.;
- Gromisch, Christopher M.;
- Mosaddhegi, Julie Z.;
- Gromisch, Matthew S.;
- Jundi, Bakr;
- Lukassen, Soeren;
- Carstensen, Saskia;
- Denis, Ridiane;
- Belkina, Anna C.;
- Baron, Rebecca M.;
- Pinilla-Vera, Mayra;
- Mueller, Meike;
- Kimberly, W. Taylor;
- Goldstein, Joshua N.;
- Lehmann, Irina;
- Shih, Angela R.;
- Eils, Roland;
- Levy, Bruce D.
Publication type:
Article
DEspRhigh neutrophils are associated with critical illness in COVID-19.
Published in:
Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-01943-7
By:
- deKay, Joanne T.;
- Emery, Ivette F.;
- Rud, Jonathan;
- Eldridge, Ashley;
- Lord, Christine;
- Gagnon, David J.;
- May, Teresa L.;
- Herrera, Victoria L. M.;
- Ruiz-Opazo, Nelson;
- Riker, Richard R.;
- Sawyer, Douglas B.;
- Ryzhov, Sergey;
- Seder, David B.
Publication type:
Article
Spontaneous combined hyperlipidemia, coronary heart disease and decreased survival in Dahl salt-sensitive hypertensive rats transgenic for human cholesteryl ester transfer protein.
Published in:
Nature Medicine, 1999, v. 5, n. 12, p. 1383, doi. 10.1038/70956
By:
- Herrera, Victoria L. M.;
- Makrides, Savvas C.;
- Xie, Hou Xiang;
- Adari, Hedy;
- Krauss, Ronald M.;
- Ryan, Una S.;
- Ruiz-Opazo, Nelson
Publication type:
Article
Anti-DEspR antibody treatment improves survival and reduces neurologic deficits in a hypertensive, spontaneous intracerebral hemorrhage (hsICH) rat model.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-28149-3
By:
- Herrera, Victoria L. M.;
- Gromisch, Christopher M.;
- Decano, Julius L.;
- Pasion, Khristine Amber;
- Tan, Glaiza L. A.;
- Hua, Ning;
- Takahashi, Courtney E.;
- Greer, David M.;
- Ruiz-Opazo, Nelson
Publication type:
Article
"Rogue" neutrophil-subset [DEspR+CD11b+/CD66b+] immunotype is an actionable therapeutic target for neutrophilic inflammation-mediated tissue injury - studies in human, macaque and rat LPS-inflammation models.
Published in:
Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.1008390
By:
- Carstensen, Saskia;
- Müller, Meike;
- Tan, Glaiza L. A.;
- Pasion, Khristine Amber;
- Hohlfeld, Jens M.;
- Herrera, Victoria L. M.;
- Ruiz-Opazo, Nelson
Publication type:
Article
11.7 Tesla magnetic resonance microimaging of laryngeal tissue architecture.
Published in:
Laryngoscope, 2009, v. 119, n. 11, p. 2187, doi. 10.1002/lary.20643
By:
- Herrera, Victoria L. M.;
- Viereck, Jason C.;
- Lopez-Guerra, Gerardo;
- Kumai, Yoshihiko;
- Kobler, James;
- Karajanagi, Sandeep;
- Park, Hyoungshin;
- Hillman, Robert;
- Zeitels, Steven M.
Publication type:
Article
Worse Renal Disease in Postmenopausal F2[Dahl S x R]-Intercross Rats: Detection of Novel QTLs Affecting Hypertensive Kidney Disease.
Published in:
PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0056096
By:
- Herrera, Victoria L. M.;
- Pasion, Khristine A.;
- Moran, Ann Marie;
- Ruiz-Opazo, Nelson
Publication type:
Article
Analysis of CD45- [CD34+/KDR+] Endothelial Progenitor Cells as Juvenile Protective Factors in a Rat Model of Ischemic-Hemorrhagic Stroke.
Published in:
PLoS ONE, 2013, v. 8, n. 1, p. 1, doi. 10.1371/journal.pone.0055222
By:
- Decano, Julius L.;
- Moran, Ann Marie;
- Giordano, Nicholas;
- Ruiz-Opazo, Nelson;
- Herrera, Victoria L. M.
Publication type:
Article
Differential Genetic Basis for Pre-Menopausal and Post-Menopausal Salt- Sensitive Hypertension.
Published in:
PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0043160
By:
- Herrera, Victoria L. M.;
- Pasion, Khristine A.;
- Moran, Ann Marie;
- Ruiz-Opazo, Nelson;
- Adamovic, Tatjana
Publication type:
Article
Dahl (S x R) Congenic Strain Analysis Confirms and Defines a Chromosome 5 Female-Specific Blood Pressure Quantitative Trait Locus to ,7 Mbp.
Published in:
PLoS ONE, 2012, v. 7, n. 7, p. 1, doi. 10.1371/journal.pone.0042214
By:
- Herrera, Victoria L. M.;
- Pasion, Khristine A.;
- Moran, Ann Marie;
- Ruiz-Opazo, Nelson
Publication type:
Article
Circulating neutrophil extracellular trap (NET)-forming 'rogue' neutrophil subset, immunotype [DEspR + CD11b +], mediate multi-organ failure in COVID-19—an observational study.
Published in:
Translational Medicine Communications, 2023, v. 8, n. 1, p. 1, doi. 10.1186/s41231-023-00143-x
By:
- Herrera, Victoria L. M.;
- Bosch, Nicholas A.;
- Lok, Judith J.;
- Nguyen, Mai Q.;
- Lenae, Kaitriona A.;
- deKay, Joanne T.;
- Ryzhov, Sergey V.;
- Seder, David B.;
- Ruiz-Opazo, Nelson;
- Walkey, Allan J.
Publication type:
Article
Assessment of Canine Vocal Fold Function After Injection of a New Biomaterial Designed to Treat Phonatory Mucosal Scarring.
Published in:
Annals of Otology, Rhinology & Laryngology, 2011, v. 120, n. 3, p. 175, doi. 10.1177/000348941112000306
By:
- Karajanagi, Sandeep S.;
- Lopez-Guerra, Gerardo;
- Hyoungshin Park;
- Kobler, James B.;
- Galindo, Marilyn;
- Aanestad, Jon;
- Mehta, Daryush D.;
- Kumai, Yoshihiko;
- Giordano, Nicholas;
- d'Almeida, Anthony;
- Heaton, James T.;
- Langer, Robert;
- Herrera, Victoria L. M.;
- Faquin, William;
- Hillman, Robert E.;
- Zeitels, Steven M.
Publication type:
Article
Humanized anti-DEspR IgG4S228P antibody increases overall survival in a pancreatic cancer stem cell-xenograft peritoneal carcinomatosis ratnu/nu model.
Published in:
2021
By:
- Gromisch, Christopher M.;
- Tan, Glaiza L. A.;
- Pasion, Khristine Amber;
- Moran, Ann-Marie;
- Gromisch, Matthew S.;
- Grinstaff, Mark W.;
- Carr, Francis J.;
- Herrera, Victoria L. M.;
- Ruiz-Opazo, Nelson
Publication type:
journal article
"Rogue" [DEspR+CD11b+] neutrophil subset correlates with severity in spontaneous intracerebral hemorrhage.
Published in:
Frontiers in Neurology, 2022, v. 13, p. 1, doi. 10.3389/fneur.2022.935579
By:
- Herrera, Victoria L. M.;
- Takahashi, Courtney E.;
- Nguyen, Mai Q.;
- Mosaddeghi, Julie Z.;
- Denis, Ridiane;
- Greer, David M.;
- Ruiz-Opazo, Nelson
Publication type:
Article
Prestroke Proteomic Changes in Cerebral Microvessels in Stroke-Prone, Transgenic(hCETP)-Hyperlipidemic, Dahl Salt-Sensitive Hypertensive Rats.
Published in:
Molecular Medicine, 2011, v. 17, n. 7/8, p. 588, doi. 10.2119/molmed.2010.00228
By:
- Bergerat, Agnes;
- Decano, Julius;
- Chang-Jiun Wu;
- Hyungwon Choi;
- Nesvizhskii, Alexey I.;
- Moran, Ann Marie;
- Ruiz-Opazo, Nelson;
- Steffen, Martin;
- Herrera, Victoria L. M.
Publication type:
Article
Janus USPION modular platform (JUMP) for theranostic ultrasound-mediated targeted intratumoral microvascular imaging and DNA/miRNA delivery.
Published in:
Theranostics, 2022, v. 12, n. 18, p. 7646, doi. 10.7150/thno.78454
By:
- Whitaker, Ragnhild D.;
- Decano, Julius L.;
- Gormley, Catherine;
- Beigie, Carl A.;
- Meisel, Cari;
- Tan, Glaiza A.;
- Moran, Ann-Marie;
- Giordano, Nicholas J.;
- Yoonjee Park;
- Peng Huang;
- Andersson, Sean;
- Gantz, Donald;
- Grant, Aaron K.;
- Ruiz-Opazo, Nelson;
- Herrera, Victoria L. M.;
- Wong, Joyce Y.
Publication type:
Article
Confirmation of translatability and functionality certifies the dual endothelin 1/VEGFsp receptor (DEspR) protein.
Published in:
BMC Molecular Biology, 2016, v. 17, p. 1, doi. 10.1186/s12867-016-0066-8
By:
- Herrera, Victoria L. M.;
- Steffen, Martin;
- Moran, Ann Marie;
- Tan, Glaiza A.;
- Pasion, Khristine A.;
- Rivera, Keith;
- Pappin, Darryl J.;
- Ruiz-Opazo, Nelson
Publication type:
Article
Molecular imaging of vasa vasorum neovascularization via DEspR-targeted contrast-enhanced ultrasound micro-imaging in transgenic atherosclerosis rat model.
Published in:
2011
By:
- Decano, Julius;
- Moran, Anne;
- Ruiz-Opazo, Nelson;
- Herrera, Victoria;
- Decano, Julius L;
- Moran, Anne Marie;
- Herrera, Victoria L M
Publication type:
journal article

Found: 18

A targetable 'rogue' neutrophil-subset, [CD11b+DEspR+] immunotype, is associated with severity and mortality in acute respiratory distress syndrome (ARDS) and COVID-19-ARDS.

DEspR<sup>high</sup> neutrophils are associated with critical illness in COVID-19.

Spontaneous combined hyperlipidemia, coronary heart disease and decreased survival in Dahl salt-sensitive hypertensive rats transgenic for human cholesteryl ester transfer protein.

Anti-DEspR antibody treatment improves survival and reduces neurologic deficits in a hypertensive, spontaneous intracerebral hemorrhage (hsICH) rat model.

"Rogue" neutrophil-subset [DEspR+CD11b+/CD66b+] immunotype is an actionable therapeutic target for neutrophilic inflammation-mediated tissue injury - studies in human, macaque and rat LPS-inflammation models.

11.7 Tesla magnetic resonance microimaging of laryngeal tissue architecture.

Worse Renal Disease in Postmenopausal F2[Dahl S x R]-Intercross Rats: Detection of Novel QTLs Affecting Hypertensive Kidney Disease.

Analysis of CD45- [CD34+/KDR+] Endothelial Progenitor Cells as Juvenile Protective Factors in a Rat Model of Ischemic-Hemorrhagic Stroke.

Differential Genetic Basis for Pre-Menopausal and Post-Menopausal Salt- Sensitive Hypertension.

Dahl (S x R) Congenic Strain Analysis Confirms and Defines a Chromosome 5 Female-Specific Blood Pressure Quantitative Trait Locus to ,7 Mbp.

Circulating neutrophil extracellular trap (NET)-forming 'rogue' neutrophil subset, immunotype [DEspR + CD11b +], mediate multi-organ failure in COVID-19—an observational study.

Assessment of Canine Vocal Fold Function After Injection of a New Biomaterial Designed to Treat Phonatory Mucosal Scarring.

Humanized anti-DEspR IgG4<sup>S228P</sup> antibody increases overall survival in a pancreatic cancer stem cell-xenograft peritoneal carcinomatosis rat<sup>nu/nu</sup> model.

"Rogue" [DEspR+CD11b+] neutrophil subset correlates with severity in spontaneous intracerebral hemorrhage.

Prestroke Proteomic Changes in Cerebral Microvessels in Stroke-Prone, Transgenic(hCETP)-Hyperlipidemic, Dahl Salt-Sensitive Hypertensive Rats.

Janus USPION modular platform (JUMP) for theranostic ultrasound-mediated targeted intratumoral microvascular imaging and DNA/miRNA delivery.

Confirmation of translatability and functionality certifies the dual endothelin 1/VEGFsp receptor (DEspR) protein.

Molecular imaging of vasa vasorum neovascularization via DEspR-targeted contrast-enhanced ultrasound micro-imaging in transgenic atherosclerosis rat model.