OpenURL Connection Search

Select item for more details and to access through your institution.

Identification of neurodevelopmental gene variants implicated in age‐related brain morphological changes and cortical atrophy.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.051974
By:
- Vacher, Michael;
- Porter, Tenielle;
- Milicic, Lidija;
- Dore, Vincent;
- Bourgeat, Pierrick;
- Villemagne, Victor L.L.;
- Doecke, James D.;
- Laws, Simon M.;
- Heng, Julian Ik‐Tsen
Publication type:
Article
Reinforcing the association between distal 1q CNVs and structural brain disorder: A case of a complex 1q43-q44 CNV and a review of the literature.
Published in:
American Journal of Medical Genetics. Part B: Neuropsychiatric Genetics, 2016, v. 171B, n. 3, p. 458, doi. 10.1002/ajmg.b.32427
By:
- Hemming, Isabel A.;
- Forrest, Alistair R. R.;
- Shipman, Peter;
- Woodward, Karen J.;
- Walsh, Peter;
- Ravine, David G.;
- Heng, Julian Ik‐Tsen
Publication type:
Article
The HSA21 gene EURL/C21ORF91 controls neurogenesis within the cerebral cortex and is implicated in the pathogenesis of Down Syndrome.
Published in:
Scientific Reports, 2016, p. 29514, doi. 10.1038/srep29514
By:
- Li, Shan Shan;
- Qu, Zhengdong;
- Haas, Matilda;
- Ngo, Linh;
- Heo, You Jeong;
- Kang, Hyo Jung;
- Britto, Joanne Maria;
- Cullen, Hayley Daniella;
- Vanyai, Hannah Kate;
- Tan, Seong-Seng;
- Chan-Ling, Tailoi;
- Gunnersen, Jenny Margaret;
- Heng, Julian Ik-Tsen
Publication type:
Article
Understanding the impact of ZBTB18 missense variation on transcription factor function in neurodevelopment and disease.
Published in:
Journal of Neurochemistry, 2022, v. 161, n. 3, p. 219, doi. 10.1111/jnc.15572
By:
- Heng, Julian I.‐T.;
- Viti, Leon;
- Pugh, Kye;
- Marshall, Owen J.;
- Agostino, Mark
Publication type:
Article
Neurogenin 2 controls cortical neuron migration through regulation of Rnd2.
Published in:
Nature, 2008, v. 455, n. 7209, p. 114, doi. 10.1038/nature07198
By:
- Heng, Julian Ik-Tsen;
- Nguyen, Laurent;
- Castro, Diogo S.;
- Zimmer, Céline;
- Wildner, Hendrik;
- Armant, Olivier;
- Skowronska-Krawczyk, Dorota;
- Bedogni, Francesco;
- Matter, Jean-Marc;
- Hevner, Robert;
- Guillemot, François
Publication type:
Article
The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein.
Published in:
Nature Cell Biology, 2008, v. 10, n. 6, p. 643, doi. 10.1038/ncb1727
By:
- Xudong Zhao;
- Julian Ik-Tsen Heng;
- Guardavaccaro, Daniele;
- Richeng Jiang;
- Pagano, Michele;
- Guillemot, Francois;
- Iavarone, Antonio;
- Lasorella, Anna
Publication type:
Article
The role of class I HLH genes in neural development—have they been overlooked?
Published in:
BioEssays, 2003, v. 25, n. 7, p. 709, doi. 10.1002/bies.10299
By:
- Ik Tsen Heng, Julian;
- Seong-Seng Tan
Publication type:
Article
Further evidence for distinct traits associated with RBM10 missense variants.
Published in:
Clinical Genetics, 2022, v. 102, n. 2, p. 161, doi. 10.1111/cge.14163
By:
- Poulton, Cathryn;
- Baynam, Gareth;
- Pugh, Kye;
- Mason, Michael;
- Kiraly‐Borri, Catherine;
- Gration, Dylan;
- Dreyer, Lauren;
- Viti, Leon;
- Agostino, Mark;
- Heng, Julian Ik‐Tsen
Publication type:
Article
Editorial: Transcription and chromatin regulators in neurodevelopmental disorders.
Published in:
Frontiers in Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fnins.2022.1023580
By:
- van den Berg, Debbie L. C.;
- Heng, Julian Ik-Tsen;
- Sessa, Alessandro;
- Dias, Cristina
Publication type:
Article
Familial cortical dysplasia caused by mutation in the mammalian target of rapamycin regulator NPRL3.
Published in:
2016
By:
- Sim, Joe C.;
- Scerri, Thomas;
- Fanjul‐Fernández, Miriam;
- Riseley, Jessica R.;
- Gillies, Greta;
- Pope, Kate;
- van Roozendaal, Hanna;
- Heng, Julian I.;
- Mandelstam, Simone A.;
- McGillivray, George;
- MacGregor, Duncan;
- Kannan, Lakshminarayanan;
- Maixner, Wirginia;
- Harvey, A. Simon;
- Amor, David J.;
- Delatycki, Martin B.;
- Crino, Peter B.;
- Bahlo, Melanie;
- Lockhart, Paul J.;
- Leventer, Richard J.
Publication type:
journal article
A review of structural brain abnormalities in Pallister‐Killian syndrome.
Published in:
Molecular Genetics & Genomic Medicine, 2018, v. 6, n. 1, p. 92, doi. 10.1002/mgg3.351
By:
- Poulton, Cathryn;
- Baynam, Gareth;
- Yates, Clarissa;
- Alinejad‐Rokny, Hamid;
- Williams, Simon;
- Wright, Helen;
- Woodward, Karen J.;
- Sivamoorthy, Soruba;
- Peverall, Joanne;
- Shipman, Peter;
- Ravine, David;
- Beilby, John;
- Heng, Julian Ik‐Tsen
Publication type:
Article
Infantile neurodegenerative disorder associated with mutations in TBCD, an essential gene in the tubulin heterodimer assembly pathway.
Published in:
Human Molecular Genetics, 2016, v. 25, n. 21, p. 4635, doi. 10.1093/hmg/ddw292
By:
- Edvardson, Shimon;
- Guoling Tian;
- Cullen, Hayley;
- Vanyai, Hannah;
- Linh Ngo;
- Bhat, Saiuj;
- Aran, Adi;
- Daana, Muhannad;
- Da’amseh, Naderah;
- Abu-Libdeh, Bassam;
- Cowan, Nicholas J.;
- Ik-Tsen Heng, Julian;
- Elpeleg, Orly
Publication type:
Article
TUBB5 and its disease-associated mutations influence the terminal differentiation and dendritic spine densities of cerebral cortical neurons.
Published in:
Human Molecular Genetics, 2014, v. 23, n. 19, p. 5147, doi. 10.1093/hmg/ddu238
By:
- Ngo, Linh;
- Haas, Matilda;
- Qu, Zhengdong;
- Li, Shan Shan;
- Zenker, Jennifer;
- Teng, Kathleen Sue Lyn;
- Gunnersen, Jenny Margaret;
- Breuss, Martin;
- Habgood, Mark;
- Keays, David Anthony;
- Heng, Julian Ik-Tsen
Publication type:
Article
The Zinc Finger Transcription Factor RP58 Negatively Regulates Rnd2 for the Control of Neuronal Migration During Cerebral Cortical Development.
Published in:
Cerebral Cortex, 2015, v. 25, n. 3, p. 806, doi. 10.1093/cercor/bht277
By:
- Heng, Julian Ik-Tsen;
- Qu, Zhengdong;
- Ohtaka-Maruyama, Chiaki;
- Okado, Haruo;
- Kasai, Masataka;
- Castro, Diogo;
- Guillemot, François;
- Tan, Seong-Seng
Publication type:
Article
Pleiotropic Effects of GLP-1 and Analogs on Cell Signaling, Metabolism, and Function.
Published in:
Frontiers in Endocrinology, 2018, p. N.PAG, doi. 10.3389/fendo.2018.00672
By:
- Rowlands, Jordan;
- Heng, Julian;
- Newsholme, Philip;
- Carlessi, Rodrigo
Publication type:
Article
Quantitative neurogenetics: applications in understanding disease.
Published in:
Biochemical Society Transactions, 2021, v. 49, n. 4, p. 1621, doi. 10.1042/BST20200732
By:
- Afrasiabi, Ali;
- Keane, Jeremy T.;
- Ik-Tsen Heng, Julian;
- Palmer, Elizabeth E.;
- Lovell, Nigel H.;
- Alinejad-Rokny, Hamid
Publication type:
Article
14-3-3ζ deficient mice in the BALB/c background display behavioural and anatomical defects associated with neurodevelopmental disorders.
Published in:
Scientific Reports, 2015, p. 12434, doi. 10.1038/srep12434
By:
- Xu, Xiangjun;
- Greenberg, Zarina;
- McCarthy, Peter;
- Saleh, Eiman;
- Lopez, Angel F.;
- Ramshaw, Hayley S.;
- Schwarz, Quenten;
- Jaehne, Emily J.;
- Baune, Bernhard T.;
- Parish, Clare L.;
- Ratnayake, Udani;
- Camera, Daria;
- Heng, Julian;
- Haas, Matilda;
- Buuse, Maarten van den
Publication type:
Article
Insights into the Biology and Therapeutic Applications of Neural Stem Cells.
Published in:
Stem Cells International, 2016, p. 1, doi. 10.1155/2016/9745315
By:
- Harris, Lachlan;
- Zalucki, Oressia;
- Piper, Michael;
- Heng, Julian Ik-Tsen
Publication type:
Article
Perturbations in cortical development and neuronal network excitability arising from prenatal exposure to benzodiazepines in mice.
Published in:
European Journal of Neuroscience, 2013, v. 37, n. 10, p. 1584, doi. 10.1111/ejn.12167
By:
- Haas, Matilda;
- Qu, Zhengdong;
- Kim, Tae Hwan;
- Vargas, Ernesto;
- Campbell, Kenneth;
- Petrou, Steven;
- Tan, Seong‐Seng;
- Reid, Christopher A.;
- Heng, Julian
Publication type:
Article
Neurotransmitters regulate cell migration in the telencephalon.
Published in:
European Journal of Neuroscience, 2007, v. 26, n. 3, p. 537, doi. 10.1111/j.1460-9568.2007.05694.x
By:
- Heng, Julian Ik‐Tsen;
- Moonen, Gustave;
- Nguyen, Laurent
Publication type:
Article
General population ZBTB18 missense variants influence DNA binding and transcriptional regulation.
Published in:
Human Mutation, 2020, v. 41, n. 9, p. 1629, doi. 10.1002/humu.24069
By:
- Hemming, Isabel A.;
- Blake, Steven;
- Agostino, Mark;
- Heng, Julian I‐T.
Publication type:
Article
Disease‐associated missense variants in ZBTB18 disrupt DNA binding and impair the development of neurons within the embryonic cerebral cortex.
Published in:
Human Mutation, 2019, v. 40, n. 10, p. 1841, doi. 10.1002/humu.23803
By:
- Hemming, Isabel A.;
- Clément, Olivier;
- Gladwyn‐Ng, Ivan E.;
- Cullen, Hayley D.;
- Ng, Han Leng;
- See, Heng B.;
- Ngo, Linh;
- Ulgiati, Daniela;
- Pfleger, Kevin D.G.;
- Agostino, Mark;
- Heng, Julian I‐T.
Publication type:
Article
Brinp1-/- mice exhibit autism-like behaviour, altered memory, hyperactivity and increased parvalbumin-positive cortical interneuron density.
Published in:
Molecular Autism, 2016, v. 7, p. 1, doi. 10.1186/s13229-016-0079-7
By:
- Berkowicz, Susan R.;
- Featherby, Travis J.;
- Zhengdong Qu;
- Giousoh, Aminah;
- Borg, Natalie A.;
- Heng, Julian I.;
- Whisstock, James C.;
- Bird, Phillip I.
Publication type:
Article
Correction to: Rp58 and p27kip1 coordinate cell cycle exit and neuronal migration within the embryonic mouse cerebral cortex.
Published in:
2018
By:
- Clément, Olivier;
- Hemming, Isabel Anne;
- Gladwyn-Ng, Ivan Enghian;
- Qu, Zhengdong;
- Li, Shan Shan;
- Piper, Michael;
- Heng, Julian Ik-Tsen
Publication type:
Correction Notice
Rp58 and p27kip1 coordinate cell cycle exit and neuronal migration within the embryonic mouse cerebral cortex.
Published in:
Neural Development, 2017, v. 12, p. 1, doi. 10.1186/s13064-017-0084-3
By:
- Clément, Olivier;
- Hemming, Isabel Anne;
- Gladwyn-Ng, Ivan Enghian;
- Zhengdong Qu;
- Shan Shan Li;
- Piper, Michael;
- Ik-Tsen Heng, Julian
Publication type:
Article
Bacurd1/Kctd13 and Bacurd2/Tnfaip1 are interacting partners to Rnd proteins which influence the long-term positioning and dendritic maturation of cerebral cortical neurons.
Published in:
Neural Development, 2016, v. 11, p. 1, doi. 10.1186/s13064-016-0062-1
By:
- Gladwyn-Ng, Ivan;
- Lieven Huang;
- Linh Ngo;
- Shan Shan Li;
- Zhengdong Qu;
- Vanyai, Hannah Kate;
- Cullen, Hayley Daniella;
- Davis, John Michael;
- Ik-Tsen Heng, Julian
Publication type:
Article
Bacurd2 is a novel interacting partner to Rnd2 which controls radial migration within the developing mammalian cerebral cortex.
Published in:
Neural Development, 2015, v. 10, n. 1, p. 1, doi. 10.1186/s13064-015-0032-z
By:
- Gladwyn-Ng, Ivan Enghian;
- Shan Shan Li;
- Zhengdong Qu;
- Davis, John Michael;
- Ngo, Linh;
- Haas, Matilda;
- Singer, Jeffrey;
- Heng, Julian Ik-Tsen
Publication type:
Article
A novel heterozygous ZBTB18 missense mutation in a family with non-syndromic intellectual disability.
Published in:
Neurogenetics, 2023, v. 24, n. 4, p. 251, doi. 10.1007/s10048-023-00727-7
By:
- Li, Nana;
- Kang, Hong;
- Zou, Yanna;
- Liu, Zhen;
- Deng, Ying;
- Wang, Meixian;
- Li, Lu;
- Qin, Hong;
- Qiu, Xiaoqiong;
- Wang, Yanping;
- Zhu, Jun;
- Agostino, Mark;
- Heng, Julian I-T;
- Yu, Ping
Publication type:
Article

Found: 28

Identification of neurodevelopmental gene variants implicated in age‐related brain morphological changes and cortical atrophy.

Reinforcing the association between distal 1q CNVs and structural brain disorder: A case of a complex 1q43-q44 CNV and a review of the literature.

The HSA21 gene EURL/C21ORF91 controls neurogenesis within the cerebral cortex and is implicated in the pathogenesis of Down Syndrome.

Understanding the impact of ZBTB18 missense variation on transcription factor function in neurodevelopment and disease.

Neurogenin 2 controls cortical neuron migration through regulation of Rnd2.

The HECT-domain ubiquitin ligase Huwe1 controls neural differentiation and proliferation by destabilizing the N-Myc oncoprotein.

The role of class I HLH genes in neural development—have they been overlooked?

Further evidence for distinct traits associated with RBM10 missense variants.

Editorial: Transcription and chromatin regulators in neurodevelopmental disorders.

Familial cortical dysplasia caused by mutation in the mammalian target of rapamycin regulator NPRL3.

A review of structural brain abnormalities in Pallister‐Killian syndrome.

Infantile neurodegenerative disorder associated with mutations in TBCD, an essential gene in the tubulin heterodimer assembly pathway.

TUBB5 and its disease-associated mutations influence the terminal differentiation and dendritic spine densities of cerebral cortical neurons.

The Zinc Finger Transcription Factor RP58 Negatively Regulates Rnd2 for the Control of Neuronal Migration During Cerebral Cortical Development.

Pleiotropic Effects of GLP-1 and Analogs on Cell Signaling, Metabolism, and Function.

Quantitative neurogenetics: applications in understanding disease.

14-3-3ζ deficient mice in the BALB/c background display behavioural and anatomical defects associated with neurodevelopmental disorders.

Insights into the Biology and Therapeutic Applications of Neural Stem Cells.

Perturbations in cortical development and neuronal network excitability arising from prenatal exposure to benzodiazepines in mice.

Neurotransmitters regulate cell migration in the telencephalon.

General population ZBTB18 missense variants influence DNA binding and transcriptional regulation.

Disease‐associated missense variants in ZBTB18 disrupt DNA binding and impair the development of neurons within the embryonic cerebral cortex.

Brinp1<sup>-/-</sup> mice exhibit autism-like behaviour, altered memory, hyperactivity and increased parvalbumin-positive cortical interneuron density.

Correction to: Rp58 and p27<sup>kip1</sup> coordinate cell cycle exit and neuronal migration within the embryonic mouse cerebral cortex.

Rp58 and p27<sup>kip1</sup> coordinate cell cycle exit and neuronal migration within the embryonic mouse cerebral cortex.

Bacurd1/Kctd13 and Bacurd2/Tnfaip1 are interacting partners to Rnd proteins which influence the long-term positioning and dendritic maturation of cerebral cortical neurons.

Bacurd2 is a novel interacting partner to Rnd2 which controls radial migration within the developing mammalian cerebral cortex.

A novel heterozygous ZBTB18 missense mutation in a family with non-syndromic intellectual disability.