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Severe hypoglycaemia in type 1 diabetes mellitus: underlying drivers and potential strategies for successful prevention.
Published in:
Diabetes/Metabolism Research & Reviews, 2014, v. 30, n. 3, p. 175, doi. 10.1002/dmrr.2492
By:
- Little, S. A.;
- Leelarathna, L.;
- Barendse, S. M.;
- Walkinshaw, E.;
- Tan, H. K.;
- Lubina Solomon, A.;
- Zoysa, N.;
- Rogers, H.;
- Choudhary, P.;
- Amiel, S. A.;
- Heller, S. R.;
- Evans, M.;
- Flanagan, D.;
- Speight, J.;
- Shaw, J. A. M.
Publication type:
Article
Effect of atenolol on QTc interval lengthening during hypoglycaemia in type 1 diabetes.
Published in:
Diabetologia, 2005, v. 48, n. 7, p. 1269, doi. 10.1007/s00125-005-1796-1
By:
- Lee, S. P.;
- Harris, N. D.;
- Robinson, R. T.;
- Davies, C.;
- Ireland, R.;
- MacDonald, I. A.;
- Heller, S. R.
Publication type:
Article
Changes in cardiac repolarization during clinical episodes of nocturnal hypoglycaemia in adults with Type 1 diabetes R. Robinson et al.: Cardiac repolarization during clinical hypoglycaemia.
Published in:
Diabetologia, 2004, v. 47, n. 2, p. 312, doi. 10.1007/s00125-003-1292-4
By:
- Robinson, R. T. C. E.;
- Harris, N. D.;
- Ireland, R. H.;
- Macdonald, I. A.;
- Heller, S. R.
Publication type:
Article
The effect of pramlintide on hormonal, metabolic or symptomatic responses to insulin-induced hypoglycaemia in patients with type 1 diabetes.
Published in:
Diabetes, Obesity & Metabolism, 2005, v. 7, n. 5, p. 504, doi. 10.1111/j.1463-1326.2004.00417.x
By:
- Amiel, S. A.;
- Heller, S. R.;
- Macdonald, I. A.;
- Schwartz, S. L.;
- Klaff, L. J.;
- Ruggles, J. A.;
- Weyer, C.;
- Kolterman, O. G.;
- Maggs, D. G.
Publication type:
Article
The role of complement in the induction of antibody responses.
Published in:
Clinical & Experimental Immunology, 1983, v. 53, n. 1, p. 208
By:
- Ochs, H. D.;
- Wedgwood, R. J.;
- Frank, M. M.;
- Heller, S. R.;
- Hosea, S. W.
Publication type:
Article
Sustained type 1 diabetes self‐management: Specifying the behaviours involved and their influences.
Published in:
Diabetic Medicine, 2021, v. 38, n. 5, p. 1, doi. 10.1111/dme.14430
By:
- Hamilton, K.;
- Stanton‐Fay, S. H.;
- Chadwick, P. M.;
- Lorencatto, F.;
- Zoysa, N.;
- Gianfrancesco, C.;
- Taylor, C.;
- Coates, E.;
- Breckenridge, J. P.;
- Cooke, D.;
- Heller, S. R.;
- Michie, S.
Publication type:
Article
Reducing the burden of hypoglycaemia in people with diabetes through increased understanding: design of the Hypoglycaemia REdefining SOLutions for better liVEs (Hypo‐RESOLVE) project.
Published in:
Diabetic Medicine, 2020, v. 37, n. 6, p. 1066, doi. 10.1111/dme.14240
By:
- Galan, B. E.;
- McCrimmon, R. J.;
- Ibberson, M.;
- Heller, S. R.;
- Choudhary, P.;
- Pouwer, F.;
- Speight, J.;
- Carlton, J.;
- Pieber, T. R.;
- Rosilio, M.;
- Tack, C. J.;
- Müllenborn, M.
Publication type:
Article
Hypoglycaemia is reduced with use of inhaled Technosphere® Insulin relative to insulin aspart in type 1 diabetes mellitus.
Published in:
Diabetic Medicine, 2020, v. 37, n. 5, p. 752, doi. 10.1111/dme.14202
By:
- Seaquist, E. R.;
- Blonde, L.;
- McGill, J. B.;
- Heller, S. R.;
- Kendall, D. M.;
- Bumpass, J. B.;
- Pompilio, F. M.;
- Grant, M. L.
Publication type:
Article
What are the characteristics of the best type 1 diabetes patient education programmes (from diagnosis to long‐term care), do they improve outcomes and what is required to make them more effective?
Published in:
Diabetic Medicine, 2020, v. 37, n. 4, p. 545, doi. 10.1111/dme.14268
By:
- Heller, S. R.;
- Gianfrancesco, C.;
- Taylor, C.;
- Elliott, J.
Publication type:
Article
How has psycho‐behavioural research advanced our understanding of hypoglycaemia in type 1 diabetes?
Published in:
Diabetic Medicine, 2020, v. 37, n. 3, p. 409, doi. 10.1111/dme.14205
By:
- Hendrieckx, C.;
- Gonder‐Frederick, L.;
- Heller, S. R.;
- Snoek, F. J.;
- Speight, J.
Publication type:
Article
Salbutamol‐induced electrophysiological changes show no correlation with electrophysiological changes during hyperinsulinaemic–hypoglycaemic clamp in young people with Type 1 diabetes.
Published in:
Diabetic Medicine, 2018, v. 35, n. 9, p. 1264, doi. 10.1111/dme.13650
By:
- Novodvorsky, P.;
- Bernjak, A.;
- Robinson, E. J.;
- Iqbal, A.;
- Macdonald, I. A.;
- Jacques, R. M.;
- Marques, J. L. B.;
- Sheridan, P. J.;
- Heller, S. R.
Publication type:
Article
A systematic review of interventions to improve outcomes for young adults with Type 1 diabetes.
Published in:
Diabetic Medicine, 2017, v. 34, n. 6, p. 753, doi. 10.1111/dme.13276
By:
- O'Hara, M. C.;
- Hynes, L.;
- O'Donnell, M.;
- Nery, N.;
- Byrne, M.;
- Heller, S. R.;
- Dinneen, S. F.
Publication type:
Article
Severe hypoglycaemia in adults with insulin-treated diabetes: impact on healthcare resources.
Published in:
Diabetic Medicine, 2016, v. 33, n. 4, p. 471, doi. 10.1111/dme.12844
By:
- Heller, S. R.;
- Frier, B. M.;
- Hersløv, M. L.;
- Gundgaard, J.;
- Gough, S. C. L.
Publication type:
Article
Characterizing problematic hypoglycaemia: iterative design and preliminary psychometric validation of the Hypoglycaemia Awareness Questionnaire (HypoA-Q).
Published in:
Diabetic Medicine, 2016, v. 33, n. 3, p. 376, doi. 10.1111/dme.12824
By:
- Speight, J.;
- Barendse, S. M.;
- Singh, H.;
- Little, S. A.;
- Inkster, B.;
- Frier, B. M.;
- Heller, S. R.;
- Rutter, M. K.;
- Shaw, J. A. M.
Publication type:
Article
A cluster randomized controlled non-inferiority trial of 5-day Dose Adjustment for Normal Eating (DAFNE) training delivered over 1 week versus 5-day DAFNE training delivered over 5 weeks: the DAFNE 5 × 1-day trial.
Published in:
2015
By:
- Elliott, J.;
- Rankin, D.;
- Jacques, R. M.;
- Lawton, J.;
- Emery, C. J.;
- Campbell, M. J.;
- Dixon, S.;
- Heller, S. R.
Publication type:
Journal Article
A cluster randomized controlled non-inferiority trial of 5-day Dose Adjustment for Normal Eating (DAFNE) training delivered over 1 week versus 5-day DAFNE training delivered over 5 weeks: the DAFNE 5 × 1-day trial.
Published in:
Diabetic Medicine, 2015, v. 32, n. 3, p. 391, doi. 10.1111/dme.12621
By:
- Elliott, J.;
- Rankin, D.;
- Jacques, R. M.;
- Lawton, J.;
- Emery, C. J.;
- Campbell, M. J.;
- Dixon, S.;
- Heller, S. R.
Publication type:
Article
Substantial reductions in the number of diabetic ketoacidosis and severe hypoglycaemia episodes requiring emergency treatment lead to reduced costs after structured education in adults with Type 1 diabetes.
Published in:
Diabetic Medicine, 2014, v. 31, n. 7, p. 847, doi. 10.1111/dme.12441
By:
- Elliott, J.;
- Jacques, R. M.;
- Kruger, J.;
- Campbell, M. J.;
- Amiel, S. A.;
- Mansell, P.;
- Speight, J.;
- Brennan, A.;
- Heller, S. R.
Publication type:
Article
Insulin degludec improves glycaemic control with lower nocturnal hypoglycaemia risk than insulin glargine in basal-bolus treatment with mealtime insulin aspart in Type 1 diabetes (BEGIN® Basal-Bolus Type 1): 2-year results of a randomized clinical trial
Published in:
Diabetic Medicine, 2013, v. 30, n. 11, p. 1293, doi. 10.1111/dme.12243
By:
- Bode, B. W.;
- Buse, J. B.;
- Fisher, M.;
- Garg, S. K.;
- Marre, M.;
- Merker, L.;
- Renard, E.;
- Russell‐Jones, D. L.;
- Hansen, C. T.;
- Rana, A.;
- Heller, S. R.
Publication type:
Article
Insulin degludec improves glycaemic control with lower nocturnal hypoglycaemia risk than insulin glargine in basal-bolus treatment with mealtime insulin aspart in Type 1 diabetes (BEGIN® Basal-Bolus Type 1): 2-year results of a...
Published in:
2013
By:
- Bode, B. W.;
- Buse, J. B.;
- Fisher, M.;
- Garg, S. K.;
- Marre, M.;
- Merker, L.;
- Renard, E.;
- Russell-Jones, D. L.;
- Hansen, C. T.;
- Rana, A.;
- Heller, S. R.
Publication type:
Journal Article
Do high fasting glucose levels suggest nocturnal hypoglycaemia? The Somogyi effect-more fiction than fact?
Published in:
Diabetic Medicine, 2013, v. 30, n. 8, p. 914, doi. 10.1111/dme.12175
By:
- Choudhary, P.;
- Davies, C.;
- Emery, C. J.;
- Heller, S. R.
Publication type:
Article
Frequency of biochemical hypoglycaemia in adults with Type 1 diabetes with and without impaired awareness of hypoglycaemia: no identifiable differences using continuous glucose monitoring.
Published in:
Diabetic Medicine, 2010, v. 27, n. 6, p. 666, doi. 10.1111/j.1464-5491.2010.03006.x
By:
- Choudhary, P.;
- Geddes, J.;
- Freeman, J. V.;
- Emery, C. J.;
- Heller, S. R.;
- Frier, B. M.
Publication type:
Article
Comparing hormonal and symptomatic responses to experimental hypoglycaemia in insulin- and sulphonylurea-treated Type 2 diabetes.
Published in:
Diabetic Medicine, 2009, v. 26, n. 7, p. 665, doi. 10.1111/j.1464-5491.2009.02759.x
By:
- Choudhary, P.;
- Lonnen, K.;
- Emery, C. J.;
- MacDonald, I. A.;
- MacLeod, K. M.;
- Amiel, S. A.;
- Heller, S. R.
Publication type:
Article
Insulin detemir lowers the risk of hypoglycaemia and provides more consistent plasma glucose levels compared with NPH insulin in Type 1 diabetes.
Published in:
Diabetic Medicine, 2006, v. 23, n. 7, p. 729, doi. 10.1111/j.1464-5491.2006.01862.x
By:
- Kølendorf, K.;
- Ross, G. P.;
- Pavlic-Renar, I.;
- Perriello, G.;
- Philotheou, A.;
- Jendle, J.;
- Gall, M-A.;
- Heller, S. R.
Publication type:
Article
Improved glycaemic control with insulin glargine plus insulin lispro: a multicentre, randomized, cross-over trial in people with Type 1 diabetes.
Published in:
Diabetic Medicine, 2006, v. 23, n. 3, p. 285, doi. 10.1111/j.1464-5491.2005.01781.x
By:
- Ashwell, S. G.;
- Amiel, S. A.;
- Bilous, R. W.;
- Dashora, U.;
- Heller, S. R.;
- Hepburn, D. A.;
- Shutler, S. D.;
- Stephens, J. W.;
- Home, P. D.
Publication type:
Article
Hypoglycaemia with insulin aspart: a double-blind, randomised, crossover trial in subjects with Type 1 diabetes.
Published in:
Diabetic Medicine, 2004, v. 21, n. 7, p. 769, doi. 10.1111/j.1464-5491.2004.01244.x
By:
- Heller, S. R.;
- Colagiuri, S.;
- Vaaler, S.;
- Wolffenbuttel, B. H. R.;
- Koelendorf, K.;
- Friberg, H. H.;
- Windfeld, K.;
- Lindholm, A.
Publication type:
Article
Counter-regulatory hormone responses to hypoglycaemia in people with type 1 diabetes after 4 weeks of treatment with liraglutide adjunct to insulin: a randomized, placebo-controlled, double-blind, crossover trial.
Published in:
Diabetes, Obesity & Metabolism, 2015, v. 17, n. 8, p. 742, doi. 10.1111/dom.12473
By:
- Pieber, T. R.;
- Deller, S.;
- Korsatko, S.;
- Jensen, L.;
- Christiansen, E.;
- Madsen, J.;
- Heller, S. R.
Publication type:
Article
Unsupervised home use of an overnight closed-loop system over 3-4 weeks: a pooled analysis of randomized controlled studies in adults and adolescents with type 1 diabetes.
Published in:
Diabetes, Obesity & Metabolism, 2015, v. 17, n. 5, p. 452, doi. 10.1111/dom.12427
By:
- Thabit, H.;
- Elleri, D.;
- Leelarathna, L.;
- Allen, J. M.;
- Lubina‐Solomon, A.;
- Stadler, M.;
- Walkinshaw, E.;
- Iqbal, A.;
- Choudhary, P.;
- Wilinska, M. E.;
- Barnard, K. D.;
- Heller, S. R.;
- Amiel, S. A.;
- Evans, M. L.;
- Dunger, D. B.;
- Hovorka, R.
Publication type:
Article
Intensification of medication and glycaemic control among patients with type 2 diabetes - the ADVANCE trial.
Published in:
Diabetes, Obesity & Metabolism, 2014, v. 16, n. 5, p. 426, doi. 10.1111/dom.12238
By:
- van Dieren, S.;
- Kengne, A. P.;
- Chalmers, J.;
- Beulens, J. W. J.;
- Davis, T. M. E.;
- Fulcher, G.;
- Heller, S. R.;
- Patel, A.;
- Colagiuri, S.;
- Hamet, P.;
- Mancia, G.;
- Marre, M.;
- Neal, B.;
- Williams, B.;
- Peelen, L. M.;
- van der Schouw, Y. T.;
- Woodward, M.;
- Zoungas, S.
Publication type:
Article
The quality of clinical care in diabetes in Britain--could do better.
Published in:
2000
By:
- Heller, S R
Publication type:
Journal Article
Sudden death in young patients with Type 1 diabetes: a consequence of disease, treatment or both?
Published in:
1999
By:
- Harris, N D;
- Heller, S R
Publication type:
Journal Article
Diabetes in the undergraduate medical curriculum: a response to 'tomorrow's doctors'.
Published in:
1997
By:
- Dornan, T L;
- Grenfell, A;
- Heller, S R;
- Morrish, N;
- Scarpello, J;
- Tooke, J
Publication type:
Journal Article
The Sixth Annual Meeting of the Anglo-Danish-Dutch Diabetes Group or Fun in Fyn.
Published in:
Diabetic Medicine, 1989, v. 6, n. 3, p. 277, doi. 10.1111/j.1464-5491.1989.tb01161.x
By:
- Heller, S. R.;
- O'Rahilly, S.
Publication type:
Article
Group Education for Obese Patients with Type 2 Diabetes: Greater Success at Less Cost.
Published in:
Diabetic Medicine, 1988, v. 5, n. 6, p. 552, doi. 10.1111/j.1464-5491.1988.tb01050.x
By:
- Heller, S. R.;
- Clarke, P.;
- Daly, H.;
- Davis, I.;
- McCulloch, D. K.;
- Allison, S. P.;
- Tattersall, R. B.
Publication type:
Article
Optic Disc Swelling in Young Diabetic Patients: a Diagnostic Dilemma.
Published in:
Diabetic Medicine, 1987, v. 4, n. 3, p. 260, doi. 10.1111/j.1464-5491.1987.tb00876.x
By:
- Heller, S. R.;
- Tattersall, R. B.
Publication type:
Article
Vertebral and Paravertebral Sepsis in Diabetes: An Easily Missed Cause of Backache.
Published in:
Diabetic Medicine, 1985, v. 2, n. 5, p. 395, doi. 10.1111/j.1464-5491.1985.tb00661.x
By:
- Baldwin, N.;
- Scott, A. R.;
- Heller, S. R.;
- O'Donoghue, D.;
- Tattersall, R. B.
Publication type:
Article
Insulin Dependence: Problems with the Classification of 100 Consecutive Patients.
Published in:
Diabetic Medicine, 1985, v. 2, n. 3, p. 167, doi. 10.1111/j.1464-5491.1985.tb00627.x
By:
- Wilson, R. M.;
- Minne, P.;
- Deverill, I.;
- Heller, S. R.;
- Gelsthorpe, K.;
- Reeves, W. G.;
- Tattersall, R. B.
Publication type:
Article
Seven Years Experience of Home Management in Pregnancy in Women with Insulin-dependent Diabetes.
Published in:
Diabetic Medicine, 1984, v. 1, n. 3, p. 199, doi. 10.1111/j.1464-5491.1984.tb01953.x
By:
- Heller, S. R.;
- Lowe, J. M.;
- Johnson, I. R.;
- O'Brien, P. M. S.;
- Clarke, P.;
- Symonds, E. M.;
- Tattersall, R. B.
Publication type:
Article
Antibody to bacteriophage φX 174 synthesized by cultured human peripheral blood lymphocytes.
Published in:
Clinical & Experimental Immunology, 1985, v. 59, n. 3, p. 673
By:
- Bohnsack, J.;
- Ochs, H. D.;
- Wedgwood, R. J.;
- Heller, S. R.
Publication type:
Article
Preservation of physiological responses to hypoglycemia 2 days after antecedent hypoglycemia in patients with IDDM.
Published in:
1997
By:
- George, Emad;
- Marques, Jefferson L.;
- Harris, Nigel D.;
- Macdonald, Ian A.;
- Hardisty, Colin A.;
- Heller, Simon R.;
- George, E;
- Marques, J L;
- Harris, N D;
- Macdonald, I A;
- Hardisty, C A;
- Heller, S R
Publication type:
journal article
Double-blind evaluation of efficacy and tolerability of metformin in NIDDM.
Published in:
1991
By:
- Dornan, Timothy L.;
- Heller, Simon R.;
- Peck, Gillian M.;
- Tattersall, Robert B.;
- Dornan, T L;
- Heller, S R;
- Peck, G M;
- Tattersall, R B
Publication type:
journal article
Endocrine Pancreas in Cats With Diabetes Mellitus.
Published in:
Veterinary Pathology, 2016, v. 53, n. 1, p. 136, doi. 10.1177/0300985815591078
By:
- Zini, E.;
- Lunardi, F.;
- Zanetti, R.;
- Heller, R. S.;
- Coppola, L. M.;
- Ferro, S.;
- Guscetti, F.;
- Osto, M.;
- Lutz, T. A.;
- Reusch, C. E.;
- Cavicchioli, L.
Publication type:
Article
Exocrine Pancreas in Cats With Diabetes Mellitus.
Published in:
Veterinary Pathology, 2016, v. 53, n. 1, p. 145, doi. 10.1177/0300985815603434
By:
- Zini, E.;
- Ferro, S.;
- Lunardi, F.;
- Zanetti, R.;
- Heller, R. S.;
- Coppola, L. M.;
- Guscetti, F.;
- Osto, M.;
- Lutz, T. A.;
- Cavicchioli, L.;
- Reusch, C. E.
Publication type:
Article
Effects of adrenaline and potassium on QTc interval and QT dispersion in man.
Published in:
European Journal of Clinical Investigation, 2003, v. 33, n. 2, p. 93, doi. 10.1046/j.1365-2362.2003.01123.x
By:
- Lee, S.;
- Harris, N. D.;
- Robinson, R. T.;
- Yeoh, L.;
- Macdonald, I. A.;
- Heller, S. R.
Publication type:
Article
Improved glucose tolerance and acinar dysmorphogenesis by targeted expression of transcription factor PDX-1 to the exocrine pancreas.
Published in:
2001
By:
- Heller, R. Scott;
- Heller, R S;
- Stoffers, D A;
- Bock, T;
- Svenstrup, K;
- Jensen, J;
- Horn, T;
- Miller, C P;
- Habener, J F;
- Madsen, O D;
- Serup, P
Publication type:
journal article
Independent development of pancreatic alpha- and beta-cells from neurogenin3-expressing precursors: a role for the notch pathway in repression of premature differentiation.
Published in:
2000
By:
- Jensen, J;
- Heller, R S;
- Funder-Nielsen, T;
- Pedersen, E E;
- Lindsell, C;
- Weinmaster, G;
- Madsen, O D;
- Serup, P
Publication type:
journal article
Leptin suppression of insulin secretion by the activation of ATP-sensitive K+ channels in pancreatic beta-cells.
Published in:
1997
By:
- Kieffer, Timothy J.;
- Heller, R. Scott;
- Leech, Colin A.;
- Holz, George G.;
- Habener, Joel F.;
- Kieffer, T J;
- Heller, R S;
- Leech, C A;
- Holz, G G;
- Habener, J F
Publication type:
journal article
Insulinotropic glucagon-like peptide I receptor expression in glucagon-producing alpha-cells of the rat endocrine pancreas.
Published in:
1997
By:
- Heller, R. Scott;
- Kieffer, Timothy J.;
- Habener, Joel F.;
- Heller, R S;
- Kieffer, T J;
- Habener, J F
Publication type:
journal article
Reduced neuroendocrine and symptomatic responses to subsequent hypoglycemia after 1 episode of hypoglycemia in nondiabetic humans.
Published in:
1991
By:
- Heller, Simon R.;
- Cryer, Philip E.;
- Heller, S R;
- Cryer, P E
Publication type:
journal article
Spectra-structure relationships in carbon-13 nuclear magnetic resonance spectroscopy. Results from a large data base.
Published in:
Magnetic Resonance in Chemistry, 1979, v. 12, n. 5, p. 289, doi. 10.1002/mrc.1270120508
By:
- Milne, G. W. A.;
- Zupan, J.;
- Heller, S. R.;
- Miller, J. A.
Publication type:
Article
A carbon-13 nuclear magnetic resonance spectral data base and search system.
Published in:
Magnetic Resonance in Chemistry, 1978, v. 11, n. 11, p. 535, doi. 10.1002/mrc.1270111102
By:
- Dalrymple, D. L.;
- Wilkins, C. L.;
- Milne, G. W. A.;
- Heller, S. R.
Publication type:
Article

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