Works by Helin, Semi

Results: 40

Mesolimbic opioid-dopamine interaction is disrupted in obesity but recovered by weight loss following bariatric surgery.

Published in:

Translational Psychiatry, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41398-021-01370-2

By:

Karlsson, Henry K.;
Tuominen, Lauri;
Helin, Semi;
Salminen, Paulina;
Nuutila, Pirjo;
Nummenmaa, Lauri

Publication type:

Article

Effects of intravenous glucose on dopaminergic function in the human brain in vivo.

Published in:

Synapse, 2007, v. 61, n. 9, p. 748, doi. 10.1002/syn.20418

By:

Haltia, Lauri T.;
Rinne, Juha O.;
Merisaari, Harri;
Maguire, Ralph P.;
Savontaus, Eriika;
Helin, Semi;
Någren, Kjell;
Kaasinen, Valtteri

Publication type:

Article

P2X 7-receptor binding in new-onset and secondary progressive MS – a [11C]SMW139 PET study.

Published in:

EJNMMI Research, 2024, v. 14, n. 1, p. 1, doi. 10.1186/s13550-024-01186-3

By:

Lehto, Jussi;
Aarnio, Richard;
Tuisku, Jouni;
Sucksdorff, Marcus;
Koivumäki, Esa Mikko;
Nylund, Marjo;
Helin, Semi;
Rajander, Johan;
Danon, Jonathan;
Gilchrist, Jayson;
Kassiou, Michael;
Oikonen, Vesa;
Airas, Laura

Publication type:

Article

APOE ε4 gene dose effect on imaging and blood biomarkers of neuroinflammation and beta-amyloid in cognitively unimpaired elderly.

Published in:

Alzheimer's Research & Therapy, 2023, v. 15, n. 1, p. 1, doi. 10.1186/s13195-023-01209-6

By:

Snellman, Anniina;
Ekblad, Laura L.;
Tuisku, Jouni;
Koivumäki, Mikko;
Ashton, Nicholas J.;
Lantero-Rodriguez, Juan;
Karikari, Thomas K.;
Helin, Semi;
Bucci, Marco;
Löyttyniemi, Eliisa;
Parkkola, Riitta;
Karrasch, Mira;
Schöll, Michael;
Zetterberg, Henrik;
Blennow, Kaj;
Rinne, Juha O.

Publication type:

Article

Feeding Releases Endogenous Opioids in Humans.

Published in:

Journal of Neuroscience, 2017, v. 37, n. 34, p. 8284, doi. 10.1523/JNEUROSCI.0976-17.2017

By:

Tuulari, Jetro J.;
Tuominen, Lauri;
de Boer, Femke E.;
Hirvonen, Jussi;
Helin, Semi;
Nuutila, Pirjo;
Nummenmaa, Lauri

Publication type:

Article

Obesity Is Associated with Decreased μ-Opioid But Unaltered Dopamine D2 Receptor Availability in the Brain.

Published in:

Journal of Neuroscience, 2015, v. 35, n. 9, p. 3959, doi. 10.1523/JNEUROSCI.4744-14.2015

By:

Karlsson, Henry K.;
Tuominen, Lauri;
Tuulari, Jetro J.;
Hirvonen, Jussi;
Parkkola, Riitta;
Helin, Semi;
Salminen, Paulina;
Nuutila, Pirjo;
Nummenmaa, Lauri

Publication type:

Article

Direct Comparison of [18F]F-DPA with [18F]DPA-714 and [11C]PBR28 for Neuroinflammation Imaging in the same Alzheimer's Disease Model Mice and Healthy Controls.

Published in:

Molecular Imaging & Biology, 2022, v. 24, n. 1, p. 157, doi. 10.1007/s11307-021-01646-5

By:

López-Picón, Francisco R.;
Keller, Thomas;
Bocancea, Diana;
Helin, Jatta S.;
Krzyczmonik, Anna;
Helin, Semi;
Damont, Annelaure;
Dollé, Frédéric;
Rinne, Juha O.;
Haaparanta-Solin, Merja;
Solin, Olof

Publication type:

Article

Dimeric [(68)Ga]DOTA-RGD peptide targeting αvβ 3 integrin reveals extracellular matrix alterations after myocardial infarction.

Published in:

2014

By:

Kiugel, Max;
Dijkgraaf, Ingrid;
Kytö, Ville;
Helin, Semi;
Liljenbäck, Heidi;
Saanijoki, Tiina;
Yim, Cheng-Bin;
Oikonen, Vesa;
Saukko, Pekka;
Knuuti, Juhani;
Roivainen, Anne;
Saraste, Antti

Publication type:

journal article

Dimeric [Ga]DOTA-RGD Peptide Targeting αβ Integrin Reveals Extracellular Matrix Alterations after Myocardial Infarction.

Published in:

Molecular Imaging & Biology, 2014, v. 16, n. 6, p. 793, doi. 10.1007/s11307-014-0752-1

By:

Kiugel, Max;
Dijkgraaf, Ingrid;
Kytö, Ville;
Helin, Semi;
Liljenbäck, Heidi;
Saanijoki, Tiina;
Yim, Cheng-Bin;
Oikonen, Vesa;
Saukko, Pekka;
Knuuti, Juhani;
Roivainen, Anne;
Saraste, Antti

Publication type:

Article

6-[18F]fluoro-L-DOPA uptake in the rat pancreas is dependent on the tracer metabolism.

Published in:

2014

By:

Kalliokoski, Teemu;
Tuomela, Johanna;
Haavisto, Laura;
Forsback, Sarita;
Snellman, Anniina;
Helin, Semi;
Grönroos, Tove J;
Solin, Olof;
Haaparanta-Solin, Merja

Publication type:

journal article

6-[F]Fluoro- l-DOPA Uptake in the Rat Pancreas is Dependent on the Tracer Metabolism.

Published in:

Molecular Imaging & Biology, 2014, v. 16, n. 3, p. 403, doi. 10.1007/s11307-013-0701-4

By:

Kalliokoski, Teemu;
Tuomela, Johanna;
Haavisto, Laura;
Forsback, Sarita;
Snellman, Anniina;
Helin, Semi;
Grönroos, Tove;
Solin, Olof;
Haaparanta-Solin, Merja

Publication type:

Article

Effect of the myeloperoxidase inhibitor AZD3241 on microglia: a PET study in Parkinson's disease.

Published in:

2015

By:

Jucaite, Aurelija;
Svenningsson, Per;
Rinne, Juha O.;
Cselényi, Zsolt;
Varnäs, Katarina;
Johnström, Peter;
Amini, Nahid;
Kirjavainen, Anna;
Helin, Semi;
Minkwitz, Margaret;
Kugler, Alan R.;
Posener, Joel A.;
Budd, Samantha;
Halldin, Christer;
Varrone, Andrea;
Farde, Lars

Publication type:

journal article

Adenosine A2A receptor availability in patients with early- and moderate-stage Parkinson's disease.

Published in:

Journal of Neurology, 2023, v. 270, n. 1, p. 300, doi. 10.1007/s00415-022-11342-1

By:

Waggan, Imran;
Rissanen, Eero;
Tuisku, Jouni;
Joutsa, Juho;
Helin, Semi;
Parkkola, Riitta;
Rinne, Juha O.;
Airas, Laura

Publication type:

Article

Seasonal Variation in the Brain μ-Opioid Receptor Availability.

Published in:

Journal of Neuroscience, 2021, v. 41, n. 6, p. 1265, doi. 10.1523/JNEUROSCI.2380-20.2020

By:

Lihua Sun;
Jing Tang;
Heidi Liljenbäck;
Aake Honkaniemi;
Virta, Jenni;
Isojärvi, Janne;
Karjalainen, Tomi;
Tatu Kantonen;
Pirjo Nuutila;
Jarmo Hietala;
Valtteri Kaasinen;
Kari Kalliokoski;
Hirvonen, Jussi;
Scheinin, Harry;
Helin, Semi;
Eerola, Kim;
Savontaus, Eriika;
Yatkin, Emrah;
Rinne, Juha O.;
Roivainen, Anne

Publication type:

Article

Neuroinflammation Appears Early on PET Imaging and Then Plateaus in a Mouse Model of Alzheimer Disease.

Published in:

Journal of Nuclear Medicine, 2018, v. 59, n. 3, p. 509, doi. 10.2967/jnumed.117.197608

By:

López-Picón, Francisco R.;
Snellman, Anniina;
Eskola, Olli;
Helin, Semi;
Solin, Olof;
Haaparanta-Solin, Merja;
Rinne, Juha O.

Publication type:

Article

A PET Tracer for Brain α2C Adrenoceptors, 11C-ORM-13070: Radiosynthesis and Preclinical Evaluation in Rats and Knockout Mice.

Published in:

Journal of Nuclear Medicine, 2014, v. 55, n. 7, p. 1171, doi. 10.2967/jnumed.113.135574

By:

Arponen, Eveliina;
Helin, Semi;
Marjamaki, Paivi;
Gronroos, Tove;
Holm, Patrik;
Loyttyniemi, Eliisa;
Nagren, Kjell;
Scheinin, Mika;
Haaparanta-Solin, Merja;
Sallinen, Jukka;
Solin, Olof

Publication type:

Article

Response to Letter on use of functional imaging by 11C-metomidate PET for primary aldosteronism subtyping.

Published in:

European Journal of Endocrinology, 2021, v. 184, n. 3, p. L11, doi. 10.1530/EJE-21-0048

By:

Soinio, Minna;
Luukkonen, Anna-Kaarina;
Seppänen, Marko;
Kemppainen, Jukka;
Seppänen, Janne;
Pienimäki, Juha-Pekka;
Leijon, Helena;
Vesterinen, Tiina;
Arola, Johanna;
Lantto, Eila;
Helin, Semi;
Tikkanen, Ilkka;
Metso, Saara;
Mirtti, Tuomas;
Heiskanen, Ilkka;
Norvio, Leena;
Tiikkainen, Mirja;
Tikkanen, Tuula;
Sane, Timo;
Välimäki, Matti

Publication type:

Article

Functional imaging with 11C-metomidate PET for subtype diagnosis in primary aldosteronism.

Published in:

European Journal of Endocrinology, 2020, v. 183, n. 6, p. 539, doi. 10.1530/EJE-20-0532

By:

Soinio, Minna;
Luukkonen, Anna-Kaarina;
Seppänen, Marko;
Kemppainen, Jukka;
Seppänen, Janne;
Pienimäki, Juha-Pekka;
Leijon, Helena;
Vesterinen, Tiina;
Arola, Johanna;
Lantto, Eila;
Helin, Semi;
Tikkanen, Ilkka;
Metso, Saara;
Mirtti, Tuomas;
Heiskanen, Ilkka;
Norvio, Leena;
Tiikkainen, Mirja;
Tikkanen, Tuula;
Sane, Timo;
Välimäki, Matti

Publication type:

Article

Cognitive Decline and Amyloid Accumulation in Patients with Mild Cognitive Impairment.

Published in:

Dementia & Geriatric Cognitive Disorders, 2012, v. 34, n. 1, p. 31, doi. 10.1159/000341580

By:

Koivunen, Jaana;
Karrasch, Mira;
Scheinin, Noora M.;
Aalto, Sargo;
Vahlberg, Tero;
Någren, Kjell;
Helin, Semi;
Viitanen, Matti;
Rinne, Juha O.

Publication type:

Article

Elevated serum chemokine CCL22 levels in first-episode psychosis: associations with symptoms, peripheral immune state and in vivo brain glial cell function.

Published in:

Translational Psychiatry, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41398-020-0776-z

By:

Laurikainen, Heikki;
Vuorela, Arja;
Toivonen, Anna;
Reinert-Hartwall, Linnea;
Trontti, Kalevi;
Lindgren, Maija;
Keinänen, Jaakko;
Mäntylä, Teemu;
Paju, Janina;
Ilonen, Tuula;
Armio, Reetta-Liina;
Walta, Maija;
Tuisku, Jouni;
Helin, Semi;
Marjamäki, Päivi;
Hovatta, Iiris;
Therman, Sebastian;
Vaarala, Outi;
Linnaranta, Outi;
Kieseppä, Tuula

Publication type:

Article

Gender differences in brain serotonin transporter availability in panic disorder.

Published in:

Journal of Psychopharmacology, 2011, v. 25, n. 7, p. 952, doi. 10.1177/0269881110389207

By:

Maron, Eduard;
Tõru, Innar;
Hirvonen, Jussi;
Tuominen, Lauri;
Lumme, Ville;
Vasar, Veiko;
Shlik, Jakov;
Nutt, David J;
Helin, Semi;
Någren, Kjell;
Tiihonen, Jari;
Hietala, Jarmo

Publication type:

Article

[11C]carfentanil PET imaging for studying the peripheral opioid system in vivo: effect of photoperiod on mu-opioid receptor availability in brown adipose tissue.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2023, v. 50, n. 2, p. 266, doi. 10.1007/s00259-022-05969-5

By:

Sun, Lihua;
Aarnio, Richard;
Herre, Erika Atencio;
Kärnä, Salli;
Palani, Senthil;
Virtanen, Helena;
Liljenbäck, Heidi;
Virta, Jenni;
Honkaniemi, Aake;
Oikonen, Vesa;
Han, Chunlei;
Laurila, Sanna;
Bucci, Marco;
Helin, Semi;
Yatkin, Emrah;
Nummenmaa, Lauri;
Nuutila, Pirjo;
Tang, Jing;
Roivainen, Anne

Publication type:

Article

Effects of age, BMI and sex on the glial cell marker TSPO — a multicentre [11C]PBR28 HRRT PET study.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2019, v. 46, n. 11, p. 2329, doi. 10.1007/s00259-019-04403-7

By:

Tuisku, Jouni;
Plavén-Sigray, Pontus;
Gaiser, Edward C.;
Airas, Laura;
Al-Abdulrasul, Haidar;
Brück, Anna;
Carson, Richard E.;
Chen, Ming-Kai;
Cosgrove, Kelly P.;
Ekblad, Laura;
Esterlis, Irina;
Farde, Lars;
Forsberg, Anton;
Halldin, Christer;
Helin, Semi;
Kosek, Eva;
Lekander, Mats;
Lindgren, Noora;
Marjamäki, Päivi;
Rissanen, Eero

Publication type:

Article

Regulation of human brown adipose tissue by adenosine and A2A receptors - studies with [15O]H2O and [11C]TMSX PET/CT.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2019, v. 46, n. 3, p. 743, doi. 10.1007/s00259-018-4120-2

By:

Lahesmaa, Minna;
Oikonen, Vesa;
Helin, Semi;
Luoto, Pauliina;
U Din, Mueez;
Pfeifer, Alexander;
Nuutila, Pirjo;
Virtanen, Kirsi A.

Publication type:

Article

Correction to: Regulation of human brown adipose tissue by adenosine and A2A receptors - studies with [15O]H2O and [11C]TMSX PET/CT.

Published in:

2018

By:

Lahesmaa, Minna;
Oikonen, Vesa;
Helin, Semi;
Luoto, Pauliina;
U Din, Mueez;
Pfeifer, Alexander;
Nuutila, Pirjo;
Virtanen, Kirsi A.

Publication type:

Correction Notice

Test-retest reliability of C-ORM-13070 in PET imaging of α-adrenoceptors in vivo in the human brain.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2015, v. 42, n. 1, p. 120, doi. 10.1007/s00259-014-2899-z

By:

Lehto, Jussi;
Virta, Jere;
Oikonen, Vesa;
Roivainen, Anne;
Luoto, Pauliina;
Arponen, Eveliina;
Helin, Semi;
Hietamäki, Johanna;
Holopainen, Aila;
Kailajärvi, Marita;
Peltonen, Juha;
Rouru, Juha;
Sallinen, Jukka;
Virtanen, Kirsi;
Volanen, Iina;
Scheinin, Mika;
Rinne, Juha

Publication type:

Article

C-ORM-13070, a novel PET ligand for brain α-adrenoceptors: radiometabolism, plasma pharmacokinetics, whole-body distribution and radiation dosimetry in healthy men.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2014, v. 41, n. 10, p. 1947, doi. 10.1007/s00259-014-2782-y

By:

Luoto, Pauliina;
Suilamo, Sami;
Oikonen, Vesa;
Arponen, Eveliina;
Helin, Semi;
Herttuainen, Jukka;
Hietamäki, Johanna;
Holopainen, Aila;
Kailajärvi, Marita;
Peltonen, Juha;
Rouru, Juha;
Sallinen, Jukka;
Scheinin, Mika;
Virta, Jere;
Virtanen, Kirsi;
Volanen, Iina;
Roivainen, Anne;
Rinne, Juha

Publication type:

Article

Folate receptor-targeted positron emission tomography of experimental autoimmune encephalomyelitis in rats.

Published in:

2019

By:

Elo, Petri;
Li, Xiang-Guo;
Liljenbäck, Heidi;
Helin, Semi;
Teuho, Jarmo;
Koskensalo, Kalle;
Saunavaara, Virva;
Marjamäki, Päivi;
Oikonen, Vesa;
Virta, Jenni;
Chen, Qingshou;
Low, Philip S.;
Knuuti, Juhani;
Jalkanen, Sirpa;
Airas, Laura;
Roivainen, Anne

Publication type:

journal article

Blood biomarkers of neurodegeneration associate differently with amyloid deposition, medial temporal atrophy, and cerebrovascular changes in APOE ε4-enriched cognitively unimpaired elderly.

Published in:

Alzheimer's Research & Therapy, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13195-024-01477-w

By:

Koivumäki, Mikko;
Ekblad, Laura;
Lantero-Rodriguez, Juan;
Ashton, Nicholas J.;
Karikari, Thomas K.;
Helin, Semi;
Parkkola, Riitta;
Lötjönen, Jyrki;
Zetterberg, Henrik;
Blennow, Kaj;
Rinne, Juha O.;
Snellman, Anniina

Publication type:

Article

Effects of intravenous placebo with glucose expectation on human basal ganglia dopaminergic function.

Published in:

Synapse, 2008, v. 62, n. 9, p. 682, doi. 10.1002/syn.20541

By:

Haltia, Lauri T.;
Rinne, Juha O.;
Helin, Semi;
Parkkola, Riitta;
Någren, Kjell;
Kaasinen, Valtteri

Publication type:

Article

Midlife insulin resistance, APOE genotype, and change in late‐life brain amyloid accumulation – a 5‐year follow‐up 11C‐PIB‐PET study.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.062101

By:

Pietilä, Elina M.;
Ekblad, Laura L.;
Snellman, Anniina;
Toppala, Sini;
Tuisku, Jouni;
Helin, Semi;
Viitanen, Matti;
Jula, Antti;
Rinne, Juha O.

Publication type:

Article

Brain beta‐amyloid in twin pairs discordant for episodic memory performance: Neuroimaging: Imaging genetics.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.045741

By:

Lindgren, Noora;
Karjalainen, Tomi;
Ekblad, Laura L.;
Helin, Semi;
Karrasch, Mira;
Teuho, Jarmo;
Tuisku, Jouni;
Kaprio, Jaakko;
Rinne, Juha O.;
Vuoksimaa, Eero

Publication type:

Article

Effect of APOE‐E4 gene dose on regional early neuroinflammation and beta‐amyloid deposition in cognitively normal elderly volunteers: Neuroimaging / imaging and genetics.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043359

By:

Snellman, Anniina;
Ekblad, Laura L.;
Tuisku, Jouni;
Helin, Semi;
Bucci, Marco;
Karjalainen, Tomi;
Parkkola, Riitta;
Karrasch, Mira;
Rinne, Juha O.

Publication type:

Article

O2‐03‐01: MIDLIFE INSULIN RESISTANCE AND LATE‐LIFE COGNITION, BRAIN AMYLOID ACCUMULATION, AND CEREBROVASCULAR LESIONS.

Published in:

Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P613, doi. 10.1016/j.jalz.2018.06.2651

By:

Ekblad, Laura L.;
Toppala, Sini;
Lotjonen, Jyrki;
Karrasch, Mira;
Johansson, Jarkko;
Helin, Semi;
Puukka, Pauli;
Laine, Hanna;
Jula, Antti;
Viitanen, Matti;
Rinne, Juha O.

Publication type:

Article

Endogenous Opioid Release After Orgasm in Man: A Combined PET/Functional MRI Study.

Published in:

Journal of Nuclear Medicine, 2023, v. 64, n. 8, p. 1310, doi. 10.2967/jnumed.123.265512

By:

Jern, Patrick;
Jinglu Chen;
Jouni Tuisku;
Tiina Saanijoki;
Hirvonen, Jussi;
Lukkarinen, Lasse;
Manninen, Sandra;
Helin, Semi;
Putkinen, Vesa;
Nummenmaa, Lauri

Publication type:

Article

Comparison of: (2 S ,4 R)-4-[18F]Fluoroglutamine, [11C]Methionine, and 2-Deoxy-2-[18F]Fluoro- D -Glucose and Two Small-Animal PET/CT Systems Imaging Rat Gliomas.

Published in:

Frontiers in Oncology, 2021, v. 11, p. 1, doi. 10.3389/fonc.2021.730358

By:

Miner, Maxwell W. G.;
Liljenbäck, Heidi;
Virta, Jenni;
Helin, Semi;
Eskola, Olli;
Elo, Petri;
Teuho, Jarmo;
Seppälä, Kerttu;
Oikonen, Vesa;
Yang, Guangli;
Kindler-Röhrborn, Andrea;
Minn, Heikki;
Li, Xiang-Guo;
Roivainen, Anne

Publication type:

Article

Insulin resistance and body mass index are associated with TSPO PET in cognitively unimpaired elderly.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2023, v. 43, n. 9, p. 1588, doi. 10.1177/0271678X231172519

By:

Ekblad, Laura L;
Tuisku, Jouni;
Koivumäki, Mikko;
Helin, Semi;
Rinne, Juha O;
Snellman, Anniina

Publication type:

Article

Adenosine A2A receptors in secondary progressive multiple sclerosis: a [11C]TMSX brain PET study.

Published in:

Journal of Cerebral Blood Flow & Metabolism, 2013, v. 33, n. 9, p. 1394, doi. 10.1038/jcbfm.2013.85

By:

Rissanen, Eero;
Virta, Jere R;
Paavilainen, Teemu;
Tuisku, Jouni;
Helin, Semi;
Luoto, Pauliina;
Parkkola, Riitta;
Rinne, Juha O;
Airas, Laura

Publication type:

Article

Human biodistribution and radiation dosimetry of 11C-( R)-PK11195, the prototypic PET ligand to image inflammation.

Published in:

European Journal of Nuclear Medicine & Molecular Imaging, 2010, v. 37, n. 3, p. 606, doi. 10.1007/s00259-009-1298-3

By:

Hirvonen, Jussi;
Roivainen, Anne;
Virta, Jere;
Helin, Semi;
Någren, Kjell;
Rinne, Juha O.

Publication type:

Article

In-target production of [11C]CH4 from a nitrogen/hydrogen gas target as a function of beam current, irradiation time, and target temperature.

Published in:

EJNMMI Radiopharmacy & Chemistry, 2024, v. 9, n. 1, p. 1, doi. 10.1186/s41181-024-00255-1

By:

Helin, Semi;
Rajander, Johan;
Aromaa, Jussi;
Arponen, Eveliina;
Helin, Jatta S.;
Solin, Olof

Publication type:

Article