Works by Helge Ræder

Results: 41

Cell identity dynamics and insight into insulin secretagogues when employing stem cell-derived islets for disease modeling.

Published in:

Frontiers in Bioengineering & Biotechnology, 2024, p. 1, doi. 10.3389/fbioe.2024.1392575

By:

Chencheng Wang;
Abadpour, Shadab;
Aizenshtadt, Aleksandra;
Dalmao-Fernandez, Andrea;
Høyem, Merete;
Wilhelmsen, Ingrid;
Stokowiec, Justyna;
Olsen, Petter Angell;
Krauss, Stefan;
Chera, Simona;
Ghila, Luiza;
Ræder, Helge;
Scholz, Hanne

Publication type:

Article

Xeno-free generation of human induced pluripotent stem cells from donor-matched fibroblasts isolated from dermal and oral tissues.

Published in:

Stem Cell Research & Therapy, 2023, v. 14, n. 1, p. 1, doi. 10.1186/s13287-023-03403-7

By:

Ali, Hassan R. W.;
Suliman, Salwa;
Osman, Tarig Al-Hadi;
Carrasco, Manuel;
Bruland, Ove;
Costea, Daniela-Elena;
Ræder, Helge;
Mustafa, Kamal

Publication type:

Article

A case of X-linked hypophosphatemic rickets: complications and the therapeutic use of cinacalcet.

Published in:

European Journal of Endocrinology, 2008, v. 159, n. S1, p. S101, doi. 10.1530/EJE-08-0383

By:

Helge Ræder

Publication type:

Article

Glucose Concentration in Regulating Induced Pluripotent Stem Cells Differentiation Toward Insulin-Producing Cells.

Published in:

Transplant International, 2024, p. 1, doi. 10.3389/ti.2024.11900

By:

Chencheng Wang;
Abadpour, Shadab;
Olsen, Petter Angell;
Daxin Wang;
Stokowiec, Justyna;
Chera, Simona;
Ghila, Luiza;
Ræder, Helge;
Krauss, Stefan;
Aizenshtadt, Aleksandra;
Scholz, Hanne

Publication type:

Article

Diagnostic screening of MODY2/ GCK mutations in the Norwegian MODY Registry.

Published in:

Pediatric Diabetes, 2008, v. 9, n. 5, p. 442, doi. 10.1111/j.1399-5448.2008.00399.x

By:

Sagen, Jørn V;
Bjørkhaug, Lise;
Molnes, Janne;
Ræder, Helge;
Grevle, Louise;
Søvik, Oddmund;
Molven, Anders;
Njølstad, Pål R

Publication type:

Article

Springboard to an academic career—A national medical student research program.

Published in:

PLoS ONE, 2018, v. 13, n. 5, p. 1, doi. 10.1371/journal.pone.0195527

By:

Jacobsen, Geir W.;
Ræder, Helge;
Stien, Marianne H.;
Munthe, Ludvig A.;
Skogen, Vegard

Publication type:

Article

Pancreatic Exocrine Dysfunction in Maturity-Onset Diabetes of the Young Type 3.

Published in:

Diabetes Care, 2008, v. 31, n. 2, p. 306, doi. 10.2337/dc07-1002

By:

Vesterhus, Mette;
Ræder, Helge;
Johansson, Stefan;
Molven, Anders;
Njølstad, Pål R.

Publication type:

Article

HNF1B mutation in a Turkish child with renal and exocrine pancreas insufficiency, diabetes and liver disease.

Published in:

Pediatric Diabetes, 2012, v. 13, n. 2, p. e1, doi. 10.1111/j.1399-5448.2011.00773.x

By:

Gonc, E Nazli;
Ozturk, Burcu Bulum;
Haldorsen, Ingfrid S;
Molnes, Janne;
Immervoll, Heike;
Ræder, Helge;
Molven, Anders;
Søvik, Oddmund;
Njølstad, Pål R

Publication type:

Article

MicroRNAs in Differentiation of Embryoid Bodies and the Teratoma Subtype of Testicular Cancer.

Published in:

Cancer Genomics & Proteomics (1109-6535), 2022, v. 19, n. 2, p. 178, doi. 10.21873/cgp.20313

By:

MYKLEBUST, METTE PERNILLE;
SØVIKNES, ANNE METTE;
HALVORSEN, OLE JOHAN;
THOR, ANNA;
DAHL, OLAV;
RÆDER, HELGE

Publication type:

Article

Mutations in the CEL VNTR cause a syndrome of diabetes and pancreatic exocrine dysfunction.

Published in:

Nature Genetics, 2006, v. 38, n. 1, p. 54, doi. 10.1038/ng1708

By:

Ræder, Helge;
Johansson, Stefan;
Holm, Pål I;
Haldorsen, Ingfrid S;
Mas, Eric;
Sbarra, Véronique;
Nermoen, Ingrid;
Eide, Stig Å;
Grevle, Louise;
Bjørkhaug, Lise;
Sagen, Jørn V;
Aksnes, Lage;
Søvik, Oddmund;
Lombardo, Dominique;
Molven, Anders;
Njølstad, Pål Rasmus

Publication type:

Article

Reduced Pancreatic Volume in Hepatocyte Nuclear Factor 1A-Maturity-Onset Diabetes of the Young

Published in:

Journal of Clinical Endocrinology & Metabolism, 2008, v. 93, n. 9, p. 3505, doi. 10.1210/jc.2008-0340

By:

Vesterhus, Mette;
Haldorsen, Ingfrid S.;
Ræder, Helge;
Molven, Anders;
Njølstad, Pål R.

Publication type:

Article

Exploring the potential of public proteomics data.

Published in:

Proteomics, 2016, v. 16, n. 2, p. 214, doi. 10.1002/pmic.201500295

By:

Vaudel, Marc;
Verheggen, Kenneth;
Csordas, Attila;
Ræder, Helge;
Berven, Frode S.;
Martens, Lennart;
Vizcaíno, Juan A.;
Barsnes, Harald

Publication type:

Article

Response to Comment on Carrasco et al. Spatial Environment Affects HNF4A Mutation-Specific Proteome Signatures and Cellular Morphology in hiPSC-Derived β-Like Cells. Diabetes 2022;71:862–869.

Published in:

Diabetes, 2023, v. 72, n. 5, p. e3, doi. 10.2337/dbi23-0007

By:

Scholz, Hanne;
Ræder, Helge

Publication type:

Article

Spatial Environment Affects HNF4A Mutation-Specific Proteome Signatures and Cellular Morphology in hiPSC-Derived β-Like Cells.

Published in:

2022

By:

Carrasco, Manuel;
Wang, Chencheng;
Søviknes, Anne M.;
Bjørlykke, Yngvild;
Abadpour, Shadab;
Paulo, Joao A.;
Tjora, Erling;
Njølstad, Pål;
Ghabayen, Jonas;
Nermoen, Ingrid;
Lyssenko, Valeriya;
Chera, Simona;
Ghila, Luiza M.;
Vaudel, Marc;
Scholz, Hanne;
Ræder, Helge

Publication type:

journal article

Carboxyl-Ester Lipase Maturity-Onset Diabetes of the Young Is Associated With Development of Pancreatic Cysts and Upregulated MAPK Signaling in Secretin-Stimulated Duodenal Fluid.

Published in:

Diabetes, 2014, v. 63, n. 1, p. 259, doi. 10.2337/db13-1012

By:

Ræder, Helge;
McAllister, Fiona E.;
Tjora, Erling;
Bhatt, Shweta;
Haldorsen, Ingfrid;
Jiang Hu;
Willems, Stefan M.;
Vesterhus, Mette;
El Ouaamari, Abdelfattah;
Manway Liu;
Ræder, Maria B.;
Immervoll, Heike;
Hoem, Dag;
Dimcevski, Georg;
Njølstad, Pål R.;
Molven, Anders;
Gygi, Steven P.;
Kulkarni, Rohit N.

Publication type:

Article

Polygenic Risk Variants for Type 2 Diabetes Susceptibility Modify Age at Diagnosis in Monogenic HNF1A Diabetes.

Published in:

Diabetes, 2010, v. 59, n. 1, p. 266, doi. 10.2337/db09-0555

By:

Allen, Hana Lango;
Johansson, Stefan;
Ellard, Sian;
Shields, Beverley;
Hertel, Jens K.;
Ræder, Helge;
Colclough, Kevin;
Molven, Anders;
Frayling, Timothy M.;
Njølstad, Pål R.;
Hattersley, Andrew T.;
Weedon, Michael N.

Publication type:

Article

Mutations in the Insulin Gene Can Cause MODY and Autoantibody-Negative Type 1 Diabetes.

Published in:

Diabetes, 2008, v. 57, n. 4, p. 1131, doi. 10.2337/db07-1467

By:

Molven, Anders;
Ringdal, Monika;
Nordbø, Anita M.;
Ræder, Helge;
Støy, Julie;
Lipkind, Gregory M.;
Steiner, Donald F.;
Philipson, Louis H.;
Bergmann, Ines;
Aarskog, Dagfinn;
Undlien, Dag E.;
Joner, Geir;
Søvik, Oddmund;
Bell, Graeme I.;
Njølstad, Pål R.

Publication type:

Article

Studies in 3,523 Norwegians and Meta-Analysis in 11,571 Subjects Indicate That Variants in the Hepatocyte Nuclear Factor 4α (HNF4A) P2 Region Are Associated With Type 2 Diabetes in Scandinavians.

Published in:

Diabetes, 2007, v. 56, n. 12, p. 3112, doi. 10.2337/db07-0513

By:

Johansson, Stefan;
Ræder, Helge;
Eide, Stig Å;
Midthjell, Kristian;
Hveem, Kristian;
Søvik, Oddmund;
Molven, Anders;
Njølstad, Pål Rasmus

Publication type:

Article

A national intercalated medical student research program – student perceptions, satisfaction, and factors associated with pursuing a PhD.

Published in:

Medical Education Online, 2022, v. 27, n. 1, p. 1, doi. 10.1080/10872981.2022.2122105

By:

Sandvei, Marie Søfteland;
Jacobsen, Geir Wenberg;
Stien, Marianne Heldal;
Ræder, Helge;
Munthe, Ludvig Andre;
Skogen, Vegard

Publication type:

Article

In vivo hyperglycaemia exposure elicits distinct period‐dependent effects on human pancreatic progenitor differentiation, conveyed by oxidative stress.

Published in:

Acta Physiologica, 2020, v. 228, n. 4, p. 1, doi. 10.1111/apha.13433

By:

Legøy, Thomas A.;
Ghila, Luiza;
Vethe, Heidrun;
Abadpour, Shadab;
Mathisen, Andreas F.;
Paulo, Joao A.;
Scholz, Hanne;
Ræder, Helge;
Chera, Simona

Publication type:

Article

Chronically Elevated Exogenous Glucose Elicits Antipodal Effects on the Proteome Signature of Differentiating Human iPSC-Derived Pancreatic Progenitors.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 7, p. 3698, doi. 10.3390/ijms22073698

By:

Ghila, Luiza;
Legøy, Thomas Aga;
Mathisen, Andreas Frøslev;
Abadpour, Shadab;
Paulo, Joao A.;
Scholz, Hanne;
Ræder, Helge;
Chera, Simona;
Lee, Man Ryul

Publication type:

Article

Anatomy and evolution of database search engines—a central component of mass spectrometry based proteomic workflows.

Published in:

Mass Spectrometry Reviews, 2020, v. 39, n. 3, p. 292, doi. 10.1002/mas.21543

By:

Verheggen, Kenneth;
Ræder, Helge;
Berven, Frode S.;
Martens, Lennart;
Barsnes, Harald;
Vaudel, Marc

Publication type:

Article

Bioinformatic Analyses of miRNA–mRNA Signature during hiPSC Differentiation towards Insulin-Producing Cells upon HNF4α Mutation.

Published in:

Biomedicines, 2020, v. 8, n. 7, p. 179, doi. 10.3390/biomedicines8070179

By:

Ghila, Luiza;
Bjørlykke, Yngvild;
Legøy, Thomas Aga;
Vethe, Heidrun;
Furuyama, Kenichiro;
Chera, Simona;
Ræder, Helge

Publication type:

Article

Hereditary hypophosphatemia in Norway: a retrospective population-based study of genotypes, phenotypes, and treatment complications.

Published in:

European Journal of Endocrinology, 2016, v. 174, n. 2, p. 125, doi. 10.1530/EJE-15-0515

By:

Rafaelsen, Silje;
Johansson, Stefan;
Ræder, Helge;
Bjerknes, Robert

Publication type:

Article

Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signalling.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. 1, doi. 10.1038/s41598-019-57305-x

By:

Legøy, Thomas Aga;
Vethe, Heidrun;
Abadpour, Shadab;
Strand, Berit L.;
Scholz, Hanne;
Paulo, Joao A.;
Ræder, Helge;
Ghila, Luiza;
Chera, Simona

Publication type:

Article

Human Organotypic Airway and Lung Organoid Cells of Bronchiolar and Alveolar Differentiation Are Permissive to Infection by Influenza and SARS-CoV-2 Respiratory Virus.

Published in:

Frontiers in Cellular & Infection Microbiology, 2022, v. 12, p. 1, doi. 10.3389/fcimb.2022.841447

By:

Ekanger, Camilla Tvedt;
Zhou, Fan;
Bohan, Dana;
Lotsberg, Maria Lie;
Ramnefjell, Maria;
Hoareau, Laurence;
Røsland, Gro Vatne;
Lu, Ning;
Aanerud, Marianne;
Gärtner, Fabian;
Salminen, Pirjo Riitta;
Bentsen, Mariann;
Halvorsen, Thomas;
Ræder, Helge;
Akslen, Lars A.;
Langeland, Nina;
Cox, Rebecca;
Maury, Wendy;
Stuhr, Linda Elin Birkhaug;
Lorens, James B.

Publication type:

Article

The Effect of Wnt Pathway Modulators on Human iPSC-Derived Pancreatic Beta Cell Maturation.

Published in:

Frontiers in Endocrinology, 2019, p. N.PAG, doi. 10.3389/fendo.2019.00293

By:

Vethe, Heidrun;
Ghila, Luiza;
Berle, Magnus;
Hoareau, Laurence;
Haaland, Øystein A.;
Scholz, Hanne;
Paulo, Joao A.;
Chera, Simona;
Ræder, Helge

Publication type:

Article

Monogenic diabetes mellitus in Norway.

Published in:

Norsk Epidemiologi, 2013, v. 23, n. 1, p. 55

By:

Søvik, Oddmund;
Irgens, Henrik Underthun;
Molnes, Janne;
Sagen, Jørn V.;
Bjørkhaug, Lise;
Ræder, Helge;
Molven, Anders;
Njølstad, Pål R.

Publication type:

Article

Exome sequencing reveals FAM20c mutations associated with fibroblast growth factor 23-related hypophosphatemia, dental anomalies, and ectopic calcification.

Published in:

Journal of Bone & Mineral Research, 2013, v. 28, n. 6, p. 1378, doi. 10.1002/jbmr.1850

By:

Rafaelsen, Silje Hjorth;
Ræder, Helge;
Fagerheim, Anne Kristine;
Knappskog, Per;
Carpenter, Thomas O;
Johansson, Stefan;
Bjerknes, Robert

Publication type:

Article

Dynamic proteome profiling of human pluripotent stem cell‐derived pancreatic progenitors.

Published in:

Stem Cells, 2020, v. 38, n. 4, p. 542, doi. 10.1002/stem.3135

By:

Loo, Larry Sai Weng;
Vethe, Heidrun;
Soetedjo, Andreas Alvin Purnomo;
Paulo, Joao A.;
Jasmen, Joanita;
Jackson, Nicholas;
Bjørlykke, Yngvild;
Valdez, Ivan A.;
Vaudel, Marc;
Barsnes, Harald;
Gygi, Steven P.;
Ræder, Helge;
Teo, Adrian Kee Keong;
Kulkarni, Rohit N.

Publication type:

Article

Long-term clinical outcome and phenotypic variability in hyperphosphatemic familial tumoral calcinosis and hyperphosphatemic hyperostosis syndrome caused by a novel GALNT3 mutation; case report and review of the literature.

Published in:

BMC Genetics, 2014, v. 15, n. 1, p. 1, doi. 10.1186/s12863-014-0098-3

By:

Rafaelsen, Silje;
Johansson, Stefan;
Ræder, Helge;
Bjerknes, Robert

Publication type:

Article

Induction of alveolar and bronchiolar phenotypes in human lung organoids.

Published in:

Physiological Reports, 2021, v. 9, n. 11, p. 1, doi. 10.14814/phy2.14857

By:

Hoareau, Laurence;
Engelsen, Agnete S. T.;
Aanerud, Marianne;
Ramnefjell, Maria Paula;
Salminen, Pirjo‐Riitta;
Gärtner, Fabian;
Halvorsen, Thomas;
Ræder, Helge;
Bentsen, Mariann H. L.

Publication type:

Article

Pancreatic Lipomatosis Is a Structural Marker in Nondiabetic Children With Mutations in Carboxyl-Ester Lipase.

Published in:

Diabetes, 2007, v. 56, n. 2, p. 444, doi. 10.2337/db06-0859

By:

Ræder, Helge;
Haldorsen, Ingfrid S.;
Ersland, Lars;
Grüner, Renate;
Taxt, Torfinn;
Søvik, Oddmund;
Molven, Anders;
Njølstad, Pål R.

Publication type:

Article

A Hepatocyte Nuclear Factor-4α Gene (HNF4A) P2 Promoter Haplotype Linked With Late-Onset Diabetes.

Published in:

Diabetes, 2006, v. 55, n. 6, p. 1899, doi. 10.2337/db05-1677

By:

Ræder, Helge;
Bjørkhaug, Lise;
Johansson, Stefan;
Mangseth, Kjersti;
Sagen, Jørn V.;
Hunting, Anne;
Følling, Ivar;
Johansen, Odd;
Bjørgaas, Marit;
Paus, Povel N.;
Søvik, Oddmund;
Molven, Anders;
Njølstad, Pål R.

Publication type:

Article

Permanent neonatal diabetes due to mutations in KCNJ11 encoding Kir6.2: patient characteristics and initial response to sulfonylurea therapy.

Published in:

2004

By:

Sagen JV;
Ræder H;
Hathout E;
Shehadeh N;
Gudmundsson K;
Bævre H;
Abuelo D;
Phornphutkul C;
Molnes J;
Bell GI;
Gloyn AL;
Hattersley AT;
Molven A;
Søvik O;
Njølstad PR;
Sagen, Jørn V;
Raeder, Helge;
Hathout, Eba;
Shehadeh, Naim;
Gudmundsson, Kolbeinn

Publication type:

journal article

Permanent Neonatal Diabetes due to Mutations in KCNJ11Encoding Kir6.2.

Published in:

Diabetes, 2004, v. 53, n. 10, p. 2713, doi. 10.2337/diabetes.53.10.2713

By:

Sagen, Jørn V.;
Ræder, Helge;
Hathout, Eba;
Shehadeh, Naim;
Gudmundsson, Kolbeinn;
Bævre, Halvor;
Abuelo, Dianne;
Phornphutkul, Chanika;
Molnes, Janne;
Bell, Graeme I.;
Gloyn, Anna L.;
Hattersley, Andrew T.;
Molven, Anders;
Søvik, Oddmund;
Njølstad, Pål R.

Publication type:

Article

Evaluation of four novel genetic variants affecting hemoglobin A1c levels in a population-based type 2 diabetes cohort (the HUNT2 study).

Published in:

BMC Medical Genetics, 2011, v. 12, n. 1, p. 20, doi. 10.1186/1471-2350-12-20

By:

Hertel, Jens K.;
Johansson, Stefan;
Ræder, Helge;
Platou, Carl G. P.;
Midthjell, Kristian;
Hveem, Kristian;
Molven, Anders;
Njølstad, Pål R

Publication type:

Article

Mutations in the VNTR of the carboxyl-ester lipase gene ( CEL) are a rare cause of monogenic diabetes.

Published in:

Human Genetics, 2010, v. 127, n. 1, p. 55, doi. 10.1007/s00439-009-0740-8

By:

Torsvik, Janniche;
Johansson, Stefan;
Johansen, Anders;
Ek, Jakob;
Minton, Jayne;
Ræder, Helge;
Ellard, Sian;
Hattersley, Andrew;
Pedersen, Oluf;
Hansen, Torben;
Molven, Anders;
Njølstad, Pål

Publication type:

Article

Reprogrammed Cells Display Distinct Proteomic Signatures Associated with Colony Morphology Variability.

Published in:

Stem Cells International, 2019, p. 1, doi. 10.1155/2019/8036035

By:

Bjørlykke, Yngvild;
Søviknes, Anne M.;
Hoareau, Laurence;
Vethe, Heidrun;
Mathisen, Andreas F.;
Chera, Simona;
Vaudel, Marc;
Ghila, Luiza M.;
Ræder, Helge

Publication type:

Article

The Chromosome 9p21 CVD- and T2D-Associated Regions in a Norwegian Population (The HUNT2 Survey).

Published in:

International Journal of Endocrinology, 2015, v. 2015, p. 1, doi. 10.1155/2015/164652

By:

Helgeland, Øyvind;
Hertel, Jens K.;
Molven, Anders;
Ræder, Helge;
Platou, Carl G. P.;
Midthjell, Kristian;
Hveem, Kristian;
Nygård, Ottar;
Njølstad, Pål R.;
Johansson, Stefan

Publication type:

Article

Absence of Diabetes and Pancreatic Exocrine Dysfunction in a Transgenic Model of <i>Carboxyl-Ester Lipase</i>-MODY (Maturity-Onset Diabetes of the Young).

Published in:

PLoS ONE, 2013, v. 8, n. 4, p. 1, doi. 10.1371/journal.pone.0060229

By:

Ræder, Helge;
Vesterhus, Mette;
El Ouaamari, Abdelfattah;
Paulo, Joao A.;
McAllister, Fiona E.;
Liew, Chong Wee;
Hu, Jiang;
Kawamori, Dan;
Molven, Anders;
Gygi, Steven P.;
Njølstad, Pål R.;
Kahn, C. Ronald;
Kulkarni, Rohit N.

Publication type:

Article