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Impact on Disease Development, Genomic Location and Biological Function of Copy Number Alterations in Non- Small Cell Lung Cancer.
Published in:
PLoS ONE, 2011, v. 6, n. 8, p. 1, doi. 10.1371/journal.pone.0022961
By:
- Yen-Tsung Huang;
- Xihong Lin;
- Chirieac, Lucian R.;
- McGovern, Ray;
- Wain, John C.;
- Heist, Rebecca S.;
- Skaug, Vidar;
- Zienolddiny, Shanbeh;
- Haugen, Aage;
- Su, Li;
- Christiani, David C.
Publication type:
Article
Polymorphisms of the NER pathway genes, ERCC1 and XPD are associated with esophageal adenocarcinoma risk.
Published in:
2008
By:
- Tse, Darren;
- Zhai, Rihong;
- Zhou, Wei;
- Heist, Rebecca;
- Asomaning, Kofi;
- Su, Li;
- Lynch, Thomas;
- Wain, John;
- Christiani, David;
- Liu, Geoffrey;
- Heist, Rebecca S;
- Lynch, Thomas J;
- Wain, John C;
- Christiani, David C
Publication type:
journal article
Clinical and Imaging Features of Non-Small Cell Lung Cancer with G12C KRAS Mutation.
Published in:
Cancers, 2021, v. 13, n. 14, p. 3572, doi. 10.3390/cancers13143572
By:
- Wu, Markus Y.;
- Zhang, Eric W.;
- Strickland, Matthew R.;
- Mendoza, Dexter P.;
- Lipkin, Lev;
- Lennerz, Jochen K.;
- Gainor, Justin F.;
- Heist, Rebecca S.;
- Digumarthy, Subba R.
Publication type:
Article
Interactions between genetic polymorphisms in the apoptotic pathway and environmental factors on esophageal adenocarcinoma risk.
Published in:
Carcinogenesis, 2011, v. 32, n. 4, p. 502, doi. 10.1093/carcin/bgq287
By:
- Wu, I-Chen;
- Zhao, Yang;
- Zhai, Rihong;
- Liu, Chen-yu.;
- Chen, Feng;
- Ter-Minassian, Monica;
- Asomaning, Kofi;
- Su, Li;
- Heist, Rebecca S.;
- Kulke, Matthew H.;
- Liu, Geoffrey;
- Christiani, David C.
Publication type:
Article
A Large-scale genetic association study of esophageal adenocarcinoma risk.
Published in:
Carcinogenesis, 2010, v. 31, n. 7, p. 1259, doi. 10.1093/carcin/bgq092
By:
- Chen-yu Liu;
- Wu, Michael C.;
- Feng Chen;
- Ter-Minassian, Monica;
- Asomaning, Kofi;
- Zhai, Rihong;
- Zhaoxi Wang;
- Li Su;
- Heist, Rebecca S.;
- Kulke, Matthew H.;
- Xihong Lin;
- Liu, Geoffrey;
- Christiani, David C.
Publication type:
Article
Epidermal growth factor A61G gene polymorphism, gastroesophageal reflux disease and esophageal adenocarcinoma risk.
Published in:
Carcinogenesis, 2009, v. 30, n. 8, p. 1363, doi. 10.1093/carcin/bgp126
By:
- Winson Y. Cheung;
- Rihong Zhai;
- Matthew H. Kulke;
- Rebecca S. Heist;
- Kofi Asomaning;
- Clement Ma;
- Zhaoxi Wang;
- Li Su;
- Michael Lanuti;
- Kenneth K. Tanabe;
- David C. Christiani;
- Geoffrey Liu
Publication type:
Article
Matrix metalloproteinase 1, 3 and 12 polymorphisms and esophageal adenocarcinoma risk and prognosis.
Published in:
Carcinogenesis, 2009, v. 30, n. 5, p. 793, doi. 10.1093/carcin/bgp065
By:
- Bradbury, Penelope A.;
- Zhai, Rihong;
- Hopkins, Jessica;
- Kulke, Matthew H.;
- Heist, Rebecca S.;
- Singh, Simron;
- Zhou, Wei;
- Ma, Clement;
- Xu, Wei;
- Asomaning, Kofi;
- Ter-Minassian, Monica;
- Wang, Zhaoxi;
- Su, Li;
- Christiani, David C.;
- Liu, Geoffrey
Publication type:
Article
Genetic polymorphisms of VEGF, interactions with cigarette smoking exposure and esophageal adenocarcinoma risk.
Published in:
Carcinogenesis, 2008, v. 29, n. 12, p. 2330, doi. 10.1093/carcin/bgn210
By:
- Rihong Zhai;
- Geoffrey Liu;
- Kofi Asomaning;
- Li Su;
- Matthew H. Kulke;
- Rebecca S. Heist;
- Norman S. Nishioka;
- Thomas J. Lynch;
- John C. Wain;
- Xihong Lin;
- David C. Christiani
Publication type:
Article
Genetic polymorphisms of MDM2, cumulative cigarette smoking and nonsmall cell lung cancer risk.
Published in:
International Journal of Cancer, 2008, v. 122, n. 4, p. 915, doi. 10.1002/ijc.23178
By:
- Liu, Geoffrey;
- Wheatley-Price, Paul;
- Zhou, Wei;
- Park, Sohee;
- Heist, Rebecca S.;
- Asomaning, Kofi;
- Wain, John C.;
- Lynch, Thomas J.;
- Su, Li;
- Christiani, David C.
Publication type:
Article
A phase Ib dose-escalation and expansion study of the oral MEK inhibitor pimasertib and PI3K/MTOR inhibitor voxtalisib in patients with advanced solid tumours.
Published in:
2018
By:
- Schram, Alison M.;
- Gandhi, Leena;
- Mita, Monica M.;
- Damstrup, Lars;
- Campana, Frank;
- Hidalgo, Manuel;
- Grande, Enrique;
- Hyman, David M.;
- Heist, Rebecca S.
Publication type:
journal article
Phase I dose-escalation trial of the oral AKT inhibitor uprosertib in combination with the oral MEK1/MEK2 inhibitor trametinib in patients with solid tumors.
Published in:
2020
By:
- Tolcher, Anthony W.;
- Kurzrock, Razelle;
- Valero, Vincente;
- Gonzalez, Rene;
- Heist, Rebecca S.;
- Tan, Antoinette R.;
- Means-Powell, Julie;
- Werner, Theresa L.;
- Becerra, Carlos;
- Wang, Chenxi;
- Leonowens, Cathrine;
- Kalyana-Sundaram, Shanker;
- Kleha, Joseph F.;
- Gauvin, Jennifer;
- D'Amelio, Anthony M.;
- Ellis, Catherine;
- Ibrahim, Nageatte;
- Yan, Li;
- D'Amelio, Anthony M Jr
Publication type:
journal article
Phase 1 study of epacadostat in combination with atezolizumab for patients with previously treated advanced nonsmall cell lung cancer.
Published in:
International Journal of Cancer, 2020, v. 147, n. 7, p. 1963, doi. 10.1002/ijc.32951
By:
- Hellmann, Matthew D.;
- Gettinger, Scott;
- Chow, Laura Q. M.;
- Gordon, Michael;
- Awad, Mark M.;
- Cha, Edward;
- Gong, Xiaohua;
- Zhou, Gongfu;
- Walker, Chris;
- Leopold, Lance;
- Heist, Rebecca S.
Publication type:
Article
Single nucleotide polymorphisms in the matrix metalloproteinase gene family and the frequency and duration of gastroesophageal reflux disease influence the risk of esophageal adenocarcinoma.
Published in:
International Journal of Cancer, 2012, v. 131, n. 11, p. 2478, doi. 10.1002/ijc.27541
By:
- Cheung, Winson Y.;
- Zhai, Rihong;
- Bradbury, Penny;
- Hopkins, Jessica;
- Kulke, Matthew H.;
- Heist, Rebecca S.;
- Asomaning, Kofi;
- Ma, Clement;
- Xu, Wei;
- Wang, Zhaoxi;
- Hooshmand, Suzanne;
- Su, Li;
- Christiani, David C.;
- Liu, Geoffrey
Publication type:
Article
Genotypic and Histological Evolution of Lung Cancers Acquiring Resistance to EGFR Inhibitors.
Published in:
Science Translational Medicine, 2011, v. 3, n. 75, p. 1, doi. 10.1126/scitranslmed.3002003
By:
- Sequist, Lecia V.;
- Waltman, Belinda A.;
- Dias-Santagata, Dora;
- Digumarthy, Subba;
- Turke, Alexa B.;
- Fidias, Panos;
- Bergethon, Kristin;
- Shaw, Alice T.;
- Gettinger, Scott;
- Cosper, Arjola K.;
- Akhavanfard, Sara;
- Heist, Rebecca S.;
- Temel, Jennifer;
- Christensen, James G.;
- Wain, John C.;
- Lynch, Thomas J.;
- Vernovsky, Kathy;
- Mark, Eugene J.;
- Lanuti, Michael;
- Iafrate, A. John
Publication type:
Article
A single-nucleotide polymorphism in the methylene tetrahydrofolate reductase (MTHFR) gene is associated with risk of radiation pneumonitis in lung cancer patients treated with thoracic radiation therapy.
Published in:
2012
By:
- Mak RH;
- Alexander BM;
- Asomaning K;
- Heist RS;
- Liu CY;
- Su L;
- Zhai R;
- Ancukiewicz M;
- Napolitano B;
- Niemierko A;
- Willers H;
- Choi NC;
- Christiani DC;
- Mak, Raymond H;
- Alexander, Brian M;
- Asomaning, Kofi;
- Heist, Rebecca S;
- Liu, Chen-yu;
- Su, Li;
- Zhai, Rihong
Publication type:
journal article
A single-nucleotide polymorphism in the methylene tetrahydrofolate reductase ( MTHFR) gene is associated with risk of radiation pneumonitis in lung cancer patients treated with thoracic radiation therapy.
Published in:
Cancer (0008543X), 2012, v. 118, n. 14, p. 3654, doi. 10.1002/cncr.26667
By:
- Mak, Raymond H.;
- Alexander, Brian M.;
- Asomaning, Kofi;
- Heist, Rebecca S.;
- Liu, Chen-yu;
- Su, Li;
- Zhai, Rihong;
- Ancukiewicz, Marek;
- Napolitano, Brian;
- Niemierko, Andrzej;
- Willers, Henning;
- Choi, Noah C.;
- Christiani, David C.
Publication type:
Article
Interactions between environmental factors and polymorphisms in angiogenesis pathway genes in esophageal adenocarcinoma risk: A case-only study.
Published in:
Cancer (0008543X), 2012, v. 118, n. 3, p. 804, doi. 10.1002/cncr.26325
By:
- Zhai, Rihong;
- Zhao, Yang;
- Liu, Geoffrey;
- Ter-Minassian, Monica;
- Wu, I.-Chen;
- Wang, Zhaoxi;
- Su, Li;
- Asomaning, Kofi;
- Chen, Feng;
- Kulke, Matthew H.;
- Lin, Xihong;
- Heist, Rebecca S.;
- Wain, John C.;
- Christiani, David C.
Publication type:
Article
Implementation and Clinical Adoption of Precision Oncology Workflows Across a Healthcare Network.
Published in:
Oncologist, 2022, v. 27, n. 11, p. 930, doi. 10.1093/oncolo/oyac134
By:
- Dias-Santagata, Dora;
- Heist, Rebecca S;
- Bard, Adam Z;
- Silva, Annacarolina F L da;
- Dagogo-Jack, Ibiayi;
- Nardi, Valentina;
- Ritterhouse, Lauren L;
- Spring, Laura M;
- Jessop, Nicholas;
- Farahani, Alexander A;
- Mino-Kenudson, Mari;
- Allen, Jill;
- Goyal, Lipika;
- Parikh, Aparna;
- Misdraji, Joseph;
- Shankar, Ganesh;
- Jordan, Justin T;
- Martinez-Lage, Maria;
- Frosch, Matthew;
- Graubert, Timothy
Publication type:
Article
Phase II Study of Cabozantinib in Patients With Bone Metastasis.
Published in:
Oncologist, 2022, v. 27, n. 7, p. 600, doi. 10.1093/oncolo/oyac083
By:
- Choy, Edwin;
- Cote, Gregory M;
- Michaelson, M Dror;
- Wirth, Lori;
- Gainor, Justin F;
- Muzikansky, Alona;
- Sequist, Lecia V;
- Sullivan, Ryan J;
- Fidias, Panagiotis M;
- Shaw, Alice;
- Heist, Rebecca S
Publication type:
Article
Revisiting MET: Clinical Characteristics and Treatment Outcomes of Patients with Locally Advanced or Metastatic, MET‐Amplified Esophagogastric Cancers.
Published in:
Oncologist, 2020, v. 25, n. 11, p. e1691, doi. 10.1634/theoncologist.2020-0274
By:
- Chaudhary, Surendra Pal;
- Kwak, Eunice L.;
- Hwang, Katie L.;
- Lennerz, Jochen K.;
- Corcoran, Ryan B.;
- Heist, Rebecca S.;
- Russo, Andrea L.;
- Parikh, Aparna;
- Borger, Darrell R.;
- Blaszkowsky, Lawrence S.;
- Faris, Jason E.;
- Murphy, Janet E.;
- Azzoli, Christopher G.;
- Roeland, Eric J.;
- Goyal, Lipika;
- Allen, Jill;
- Mullen, John T.;
- Ryan, David P.;
- Iafrate, A. John;
- Klempner, Samuel J.
Publication type:
Article
MET Exon 14 Skipping in Non-Small Cell Lung Cancer.
Published in:
Oncologist, 2016, v. 21, n. 4, p. 481, doi. 10.1634/theoncologist.2015-0510
By:
- Heist, Rebecca S.;
- Shim, Hyo Sup;
- Gingipally, Shalini;
- Mino‐Kenudson, Mari;
- Le, Long;
- Gainor, Justin F.;
- Zheng, Zongli;
- Aryee, Martin;
- Xia, Junfeng;
- Jia, Peilin;
- Jin, Hailing;
- Zhao, Zhongming;
- Pao, William;
- Engelman, Jeffrey A.;
- Iafrate, A. John
Publication type:
Article
End-of-Life Care in Patients with Metastatic Lung Cancer Harboring Epidermal Growth Factor Receptor Mutations.
Published in:
Journal of Palliative Medicine, 2016, v. 19, n. 12, p. 1316, doi. 10.1089/jpm.2016.0180
By:
- Bauman, Jessica R.;
- Piotrowska, Zofia;
- Muzikansky, Alona;
- Gallagher, Emily;
- Scribner, Emily;
- Temel, Brandon;
- Sequist, Lecia V.;
- Heist, Rebecca S.;
- Temel, Jennifer S.
Publication type:
Article
Leveraging Epidemiology and Clinical Studies of Cancer Outcomes: Recommendations and Opportunities for Translational Research.
Published in:
JNCI: Journal of the National Cancer Institute, 2013, v. 105, n. 2, p. 85, doi. 10.1093/jnci/djs473
By:
- Elena, Joanne W.;
- Travis, Lois B.;
- Simonds, Naoko I.;
- Ambrosone, Christine B.;
- Ballard-Barbash, Rachel;
- Bhatia, Smita;
- Cerhan, James R.;
- Hartge, Patricia;
- Heist, Rebecca S.;
- Kushi, Lawrence H.;
- Lash, Timothy L.;
- Morton, Lindsay M.;
- Onel, Kenan;
- Pierce, John P.;
- Robison, Leslie L.;
- Rowland, Julia H.;
- Schrag, Deborah;
- Sellers, Thomas A.;
- Seminara, Daniela;
- Shu, Xiao Ou
Publication type:
Article
Association of MDM2 T309 G and p53 Arg72 Pro polymorphisms and gastroesophageal reflux disease with survival in esophageal adenocarcinoma.
Published in:
Journal of Gastroenterology & Hepatology, 2013, v. 28, n. 9, p. 1482, doi. 10.1111/jgh.12286
By:
- Renouf, Daniel J;
- Zhai, Rihong;
- Sun, Bin;
- Xu, Wei;
- Cheung, Winson Y;
- Heist, Rebecca S;
- Kulke, Matthew H;
- Cescon, David;
- Asomaning, Kofi;
- Marshall, Ariella L;
- Li, Su;
- Christiani, David C;
- Liu, Geoffrey
Publication type:
Article

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