Works by Heinrich, Michael C.


Results: 54
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    Integrated genomic study of quadruple-WT GIST (KIT/PDGFRA/SDH/RAS pathway wild-type GIST).

    Published in:
    BMC Cancer, 2014, v. 14, p. 1, doi. 10.1186/1471-2407-14-685
    By:
    • Nannini, Margherita;
    • Astolfi, Annalisa;
    • Urbini, Milena;
    • Indio, Valentina;
    • Santini, Donatella;
    • Heinrich, Michael C.;
    • Corless, Christopher L.;
    • Ceccarelli, Claudio;
    • Saponara, Maristella;
    • Mandrioli, Anna;
    • Lolli, Cristian;
    • Ercolani, Giorgio;
    • Brandi, Giovanni;
    • Biasco, Guido;
    • Pantaleo, Maria A.
    Publication type:
    Article
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    Differential expression of neural markers in KIT and PDGFRA wild-type gastrointestinal stromal tumours.

    Published in:
    Histopathology, 2011, v. 59, n. 6, p. 1071, doi. 10.1111/j.1365-2559.2011.04071.x
    By:
    • Pantaleo, Maria A;
    • Astolfi, Annalisa;
    • Nannini, Margherita;
    • Ceccarelli, Claudio;
    • Formica, Serena;
    • Santini, Donatella;
    • Heinrich, Michael C;
    • Corless, Christopher;
    • Dei Tos, Angelo Paolo;
    • Paterini, Paola;
    • Catena, Fausto;
    • Maleddu, Alessandra;
    • Saponara, Maristella;
    • Di Battista, Monica;
    • Biasco, Guido
    Publication type:
    Article
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    Survey of Activated FLT3 Signaling in Leukemia.

    Published in:
    PLoS ONE, 2011, v. 6, n. 4, p. 1, doi. 10.1371/journal.pone.0019169
    By:
    • Ting-lei Gu;
    • Nardone, Julie;
    • Yi Wang;
    • Loriaux, Marc;
    • Villén, Judit;
    • Beausoleil, Sean;
    • Tucker, Meghan;
    • Kornhauser, Jon;
    • Jianmin Ren;
    • MacNeill, Joan;
    • Gygi, Steven P.;
    • Druker, Brian J.;
    • Heinrich, Michael C.;
    • Rush, John;
    • Polakiewicz, Roberto D.
    Publication type:
    Article
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    Correlation of KIT and PDGFRA mutational status with clinical benefit in patients with gastrointestinal stromal tumor treated with sunitinib in a worldwide treatment-use trial.

    Published in:
    2016
    By:
    • Reichardt, Peter;
    • Demetri, George D.;
    • Gelderblom, Hans;
    • Rutkowski, Piotr;
    • Im, Seock-Ah;
    • Gupta, Sudeep;
    • Yoon-Koo Kang;
    • Schöffski, Patrick;
    • Schuette, Jochen;
    • Soulières, Denis;
    • Blay, Jean-Yves;
    • Goldstein, David;
    • Fly, Kolette;
    • Xin Huang;
    • Corsaro, Massimo;
    • Lechuga, Maria Jose;
    • Martini, Jean-Francois;
    • Heinrich, Michael C.;
    • Kang, Yoon-Koo;
    • Huang, Xin
    Publication type:
    journal article
    9

    SDHA Loss-of-Function Mutations in KIT–PDGFRA Wild-Type Gastrointestinal Stromal Tumors Identified by Massively Parallel Sequencing.

    Published in:
    JNCI: Journal of the National Cancer Institute, 2011, v. 103, n. 12, p. 983, doi. 10.1093/jnci/djr130
    By:
    • Pantaleo, Maria A.;
    • Astolfi, Annalisa;
    • Indio, Valentina;
    • Moore, Richard;
    • Thiessen, Nina;
    • Heinrich, Michael C.;
    • Gnocchi, Chiara;
    • Santini, Donatella;
    • Catena, Fausto;
    • Formica, Serena;
    • Martelli, Pier Luigi;
    • Casadio, Rita;
    • Pession, Andrea;
    • Biasco, Guido
    Publication type:
    Article
    10

    CML-413: Asciminib Provides Durable Responses and a Favorable Safety Profile in Patients with Chronic Myeloid Leukemia (CML) in Chronic Phase (CP) with the T315I Mutation in a Phase 1 Study.

    Published in:
    Clinical Lymphoma, Myeloma & Leukemia, 2021, v. 21, p. S335, doi. 10.1016/S2152-2650(21)01784-5
    By:
    • Cortes, Jorge E.;
    • Hughes, Timothy P.;
    • Mauro, Michael J.;
    • Hochhaus, Andreas;
    • Réa, Delphine;
    • Goh, Yeow-Tee;
    • Janssen, J.J.W.M.;
    • Heinrich, Michael C.;
    • Talpaz, Moshe;
    • Etienne, Gabriel;
    • Breccia, Massimo;
    • Deininger, Michael;
    • le Coutre, Philipp;
    • Lang, Fabian;
    • Polydoros, Fotis;
    • Cacciatore, Silvia;
    • Stenson, Laura;
    • Dong-Wook Kim
    Publication type:
    Article
    11

    Poster: CML-413: Asciminib Provides Durable Responses and a Favorable Safety Profile in Patients with Chronic Myeloid Leukemia (CML) in Chronic Phase (CP) with the T315I Mutation in a Phase 1 Study.

    Published in:
    Clinical Lymphoma, Myeloma & Leukemia, 2021, v. 21, p. S224, doi. 10.1016/S2152-2650(21)01409-9
    By:
    • Cortes, Jorge E.;
    • Hughes, Timothy P.;
    • Mauro, Michael J.;
    • Hochhaus, Andreas;
    • Réa, Delphine;
    • Yeow-Tee Goh;
    • Janssen, J.J.W.M.;
    • Heinrich, Michael C.;
    • Talpaz, Moshe;
    • Etienne, Gabriel;
    • Breccia, Massimo;
    • Deininger, Michael;
    • le Coutre, Philipp;
    • Lang, Fabian;
    • Polydoros, Fotis;
    • Cacciatore, Silvia;
    • Stenson, Laura;
    • Dong-Wook Kim
    Publication type:
    Article
    12

    Primary Adenoid Cystic Carcinoma of the Lung.

    Published in:
    Cancer (0008543X), 2007, v. 110, n. 11, p. 2507, doi. 10.1002/cncr.23075
    By:
    • Aubry, Marie-Christine;
    • Heinrich, Michael C.;
    • Molina, Julian;
    • Lewis, Jean E.;
    • Ping Yang;
    • Cassivi, Stephen D.;
    • Corless, Christopher L.
    Publication type:
    Article
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    FGFR1 and NTRK3 actionable alterations in "Wild-Type" gastrointestinal stromal tumors.

    Published in:
    Journal of Translational Medicine, 2016, v. 14, p. 1, doi. 10.1186/s12967-016-1075-6
    By:
    • Shi, Eileen;
    • Chmielecki, Juliann;
    • Chih-Min Tang;
    • Kai Wang;
    • Heinrich, Michael C.;
    • Corless, Christopher L.;
    • Hong, David;
    • Fero, Katherine E.;
    • Murphy, James D.;
    • Fanta, Paul T.;
    • Ali, Siraj M.;
    • De Siena, Martina;
    • Burgoyne, Adam M.;
    • Movva, Sujana;
    • Madlensky, Lisa;
    • Heestand, Gregory M.;
    • Trent, Jonathan C.;
    • Kurzrock, Razelle;
    • Morosini, Deborah;
    • Ross, Jeffrey S.
    Publication type:
    Article
    15

    Patient-reported outcomes in individuals with advanced gastrointestinal stromal tumor treated with ripretinib in the fourth-line setting: analysis from the phase 3 INVICTUS trial.

    Published in:
    BMC Cancer, 2022, v. 22, n. 1, p. 1, doi. 10.1186/s12885-022-10379-9
    By:
    • Schöffski, Patrick;
    • George, Suzanne;
    • Heinrich, Michael C.;
    • Zalcberg, John R.;
    • Bauer, Sebastian;
    • Gelderblom, Hans;
    • Serrano, César;
    • Jones, Robin L.;
    • Attia, Steven;
    • D'Amato, Gina;
    • Chi, Ping;
    • Reichardt, Peter;
    • Becker, Claus;
    • Shi, Kelvin;
    • Meade, Julie;
    • Ruiz-Soto, Rodrigo;
    • Blay, Jean-Yves;
    • von Mehren, Margaret
    Publication type:
    Article
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    Outcomes of Late-Line Systemic Treatment in GIST: Does Sequence Matter?

    Published in:
    Cancers, 2024, v. 16, n. 5, p. 904, doi. 10.3390/cancers16050904
    By:
    • Thirasastr, Prapassorn;
    • Sutton, Thomas L.;
    • Joseph, Cissimol P.;
    • Lin, Heather;
    • Amini, Behrang;
    • Mayo, Skye C.;
    • Araujo, Dejka;
    • Benjamin, Robert S.;
    • Conley, Anthony P.;
    • Livingston, John A.;
    • Ludwig, Joseph;
    • Patel, Shreyaskumar;
    • Ratan, Ravin;
    • Ravi, Vinod;
    • Zarzour, Maria A.;
    • Nassif Haddad, Elise F.;
    • Nakazawa, Michael S.;
    • Zhou, Xiao;
    • Heinrich, Michael C.;
    • Somaiah, Neeta
    Publication type:
    Article
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    Clinical Benefit of Ripretinib Dose Escalation After Disease Progression in Advanced Gastrointestinal Stromal Tumor: An Analysis of the INVICTUS Study.

    Published in:
    Oncologist, 2021, v. 26, n. 11, p. e2053, doi. 10.1002/onco.13917
    By:
    • Zalcberg, John R.;
    • Heinrich, Michael C.;
    • George, Suzanne;
    • Bauer, Sebastian;
    • Schöffski, Patrick;
    • Serrano, César;
    • Gelderblom, Hans;
    • Jones, Robin L.;
    • Attia, Steven;
    • D'Amato, Gina;
    • Chi, Ping;
    • Reichardt, Peter;
    • Somaiah, Neeta;
    • Meade, Julie;
    • Reichert, Vienna;
    • Shi, Kelvin;
    • Sherman, Matthew L.;
    • Ruiz‐Soto, Rodrigo;
    • von Mehren, Margaret;
    • Blay, Jean‐Yves
    Publication type:
    Article
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    Gastrointestinal stromal tumors (GISTs) with KIT and PDGFRA mutations have distinct gene expression profiles.

    Published in:
    Oncogene, 2004, v. 23, n. 47, p. 7780, doi. 10.1038/sj.onc.1208056
    By:
    • Subramanian, Subbaya;
    • West, Robert B;
    • Corless, Christopher L;
    • Ou, Wenbin;
    • Rubin, Brian P;
    • Kent-Man Chu;
    • Suet Yi Leung;
    • Siu Tsan Yuen;
    • Zhu, Shirley;
    • Hernandez-Boussard, Tina;
    • Montgomery, Kelli;
    • Nielsen, Torsten O;
    • Patel, Rajiv M;
    • Goldblum, John R;
    • Heinrich, Michael C;
    • Fletcher, Jonathan A;
    • van de Rijn, Matt
    Publication type:
    Article
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    A precision therapy against cancers driven by KIT/PDGFRA mutations.

    Published in:
    Science Translational Medicine, 2017, v. 9, n. 414, p. 1, doi. 10.1126/scitranslmed.aao1690
    By:
    • Evans, Erica K.;
    • Gardino, Alexandra K.;
    • Kim, Joseph L.;
    • Hodous, Brian L.;
    • Shutes, Adam;
    • Davis, Alison;
    • Xing Julia Zhu;
    • Schmidt-Kittler, Oleg;
    • Wilson, Doug;
    • Wilson, Kevin;
    • DiPietro, Lucian;
    • Yulian Zhang;
    • Brooijmans, Natasja;
    • LaBranche, Timothy P.;
    • Wozniak, Agnieszka;
    • Gebreyohannes, Yemarshet K.;
    • Schöffski, Patrick;
    • Heinrich, Michael C.;
    • DeAngelo, Daniel J.;
    • Miller, Stephen
    Publication type:
    Article
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    Correction: Complementary activity of tyrosine kinase inhibitors against secondary kit mutations in imatinib-resistant gastrointestinal stromal tumours.

    Published in:
    2019
    By:
    • Serrano, César;
    • Mariño-Enríquez, Adrián;
    • Tao, Derrick L.;
    • Ketzer, Julia;
    • Eilers, Grant;
    • Zhu, Meijun;
    • Yu, Channing;
    • Mannan, Aristotle M.;
    • Rubin, Brian P.;
    • Demetri, George D.;
    • Raut, Chandrajit P.;
    • Presnell, Ajia;
    • McKinley, Arin;
    • Heinrich, Michael C.;
    • Czaplinski, Jeffrey T.;
    • Sicinska, Ewa;
    • Bauer, Sebastian;
    • George, Suzanne;
    • Fletcher, Jonathan A.
    Publication type:
    corrected article
    42

    Complementary activity of tyrosine kinase inhibitors against secondary kit mutations in imatinib-resistant gastrointestinal stromal tumours.

    Published in:
    2019
    By:
    • Serrano, César;
    • Mariño-Enríquez, Adrián;
    • Tao, Derrick L.;
    • Ketzer, Julia;
    • Eilers, Grant;
    • Zhu, Meijun;
    • Yu, Channing;
    • Mannan, Aristotle M.;
    • Rubin, Brian P.;
    • Demetri, George D.;
    • Raut, Chandrajit P.;
    • Presnell, Ajia;
    • McKinley, Arin;
    • Heinrich, Michael C.;
    • Czaplinski, Jeffrey T.;
    • Sicinska, Ewa;
    • Bauer, Sebastian;
    • George, Suzanne;
    • Fletcher, Jonathan A.
    Publication type:
    journal article
    43

    Integrated Molecular Characterization of Gastrointestinal Stromal Tumors (GIST) Harboring the Rare D842V Mutation in PDGFRA Gene.

    Published in:
    International Journal of Molecular Sciences, 2018, v. 19, n. 3, p. 732, doi. 10.3390/ijms19030732
    By:
    • Indio, Valentina;
    • Astolfi, Annalisa;
    • Tarantino, Giuseppe;
    • Urbini, Milena;
    • Patterson, Janice;
    • Nannini, Margherita;
    • Saponara, Maristella;
    • Gatto, Lidia;
    • Santini, Donatella;
    • do Valle, Italo F.;
    • Castellani, Gastone;
    • Remondini, Daniel;
    • Fiorentino, Michelangelo;
    • von Mehren, Margaret;
    • Brandi, Giovanni;
    • Biasco, Guido;
    • Heinrich, Michael C.;
    • Pantaleo, Maria Abbondanza
    Publication type:
    Article
    44

    A Functional Genomics Approach to Kaposi's Sarcoma.

    Published in:
    Annals of the New York Academy of Sciences, 2002, v. 975, n. 1, p. 180, doi. 10.1111/j.1749-6632.2002.tb05951.x
    By:
    • MOSES, ASHLEE V.;
    • JARVIS, MICHAEL A.;
    • RAGGO, CAMILO;
    • BELL, YOLANDA C.;
    • RUHL, REBECCA;
    • LUUKKONEN, B.G. MATTIAS;
    • GRIFFITH, DIANA J.;
    • WAIT, CECILY L.;
    • DRUKER, BRIAN J.;
    • HEINRICH, MICHAEL C.;
    • NELSON, JAY A.;
    • FRÜH, KLAUS
    Publication type:
    Article
    45
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    The contemporary management of cancers of the sinonasal tract in adults.

    Published in:
    CA: A Cancer Journal for Clinicians, 2023, v. 73, n. 1, p. 72, doi. 10.3322/caac.21752
    By:
    • Thawani, Rajat;
    • Kim, Myung Sun;
    • Arastu, Asad;
    • Feng, Zizhen;
    • West, Malinda T.;
    • Taflin, Nicholas F.;
    • Thein, Kyaw Zin;
    • Li, Ryan;
    • Geltzeiler, Mathew;
    • Lee, Nancy;
    • Fuller, Clifton David;
    • Grandis, Jennifer R.;
    • Floudas, Charalampos S.;
    • Heinrich, Michael C.;
    • Hanna, Ehab;
    • Chandra, Ravi A.
    Publication type:
    Article
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    A multicenter, dose-finding, phase 1b study of imatinib in combination with alpelisib as third-line treatment in patients with advanced gastrointestinal stromal tumor.

    Published in:
    BMC Cancer, 2022, v. 22, n. 1, p. 1, doi. 10.1186/s12885-022-09610-4
    By:
    • Pantaleo, Maria A.;
    • Heinrich, Michael C.;
    • Italiano, Antoine;
    • Valverde, Claudia;
    • Schöffski, Patrick;
    • Grignani, Giovanni;
    • Reyners, Anna K. L.;
    • Bauer, Sebastian;
    • Reichardt, Peter;
    • Stark, Daniel;
    • Berhanu, Ghimja;
    • Brandt, Ulrike;
    • Stefanelli, Tommaso;
    • Gelderblom, Hans
    Publication type:
    Article
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    Cancer: Oncogenes in context.

    Published in:
    Nature, 2010, v. 467, n. 7317, p. 796, doi. 10.1038/467796a
    By:
    • Heinrich, Michael C.;
    • Corless, Christopher L .
    Publication type:
    Article