Works by Heinemann, Uwe

Results: 113

Losartan prevents acquired epilepsy via TGF-β signaling suppression.

Published in:

2014

By:

Bar-Klein, Guy;
Cacheaux, Luisa P;
Kamintsky, Lyn;
Prager, Ofer;
Weissberg, Itai;
Schoknecht, Karl;
Cheng, Paul;
Kim, Soo Young;
Wood, Lydia;
Heinemann, Uwe;
Kaufer, Daniela;
Friedman, Alon

Publication type:

journal article

Losartan prevents acquired epilepsy via TGF-β signaling suppression.

Published in:

Annals of Neurology, 2014, v. 75, n. 6, p. 864, doi. 10.1002/ana.24147

By:

Bar‐Klein, Guy;
Cacheaux, Luisa P.;
Kamintsky, Lyn;
Prager, Ofer;
Weissberg, Itai;
Schoknecht, Karl;
Cheng, Paul;
Kim, Soo Young;
Wood, Lydia;
Heinemann, Uwe;
Kaufer, Daniela;
Friedman, Alon

Publication type:

Article

Seizure‐induced microvascular injury is associated with impaired neurovascular coupling and blood–brain barrier dysfunction.

Published in:

Epilepsia (Series 4), 2019, v. 60, n. 2, p. 322, doi. 10.1111/epi.14631

By:

Prager, Ofer;
Kamintsky, Lyna;
Hasam‐Henderson, Luisa A.;
Schoknecht, Karl;
Wuntke, Vera;
Papageorgiou, Ismini;
Swolinsky, Jutta;
Muoio, Valeria;
Bar‐Klein, Guy;
Vazana, Udi;
Heinemann, Uwe;
Friedman, Alon;
Kovács, Richard

Publication type:

Article

Methodological standards for in vitro models of epilepsy and epileptic seizures. A TASK1- WG4 report of the AES/ ILAE Translational Task Force of the ILAE.

Published in:

Epilepsia (Series 4), 2017, v. 58, p. 40, doi. 10.1111/epi.13901

By:

Raimondo, Joseph V.;
Heinemann, Uwe;
Curtis, Marco;
Goodkin, Howard P.;
Dulla, Chris G.;
Janigro, Damir;
Ikeda, Akio;
Lin, Chou‐Ching K.;
Jiruska, Premysl;
Galanopoulou, Aristea S.;
Bernard, Christophe

Publication type:

Article

WONOEP appraisal: Molecular and cellular biomarkers for epilepsy.

Published in:

Epilepsia (Series 4), 2016, v. 57, n. 9, p. 1354, doi. 10.1111/epi.13460

By:

Walker, Lauren E.;
Janigro, Damir;
Heinemann, Uwe;
Riikonen, Raili;
Bernard, Christophe;
Patel, Manisha

Publication type:

Article

Adenosine A1 receptor-mediated suppression of carbamazepine-resistant seizure-like events in human neocortical slices.

Published in:

Epilepsia (Series 4), 2016, v. 57, n. 5, p. 746, doi. 10.1111/epi.13360

By:

Klaft, Zin ‐ Juan;
Hollnagel, Jan ‐ Oliver;
Salar, Seda;
Calişkan, Gürsel;
Schulz, Steffen B.;
Schneider, Ulf C.;
Horn, Peter;
Koch, Arend;
Holtkamp, Martin;
Gabriel, Siegrun;
Gerevich, Zoltan;
Heinemann, Uwe

Publication type:

Article

WONOEP appraisal: Molecular and cellular imaging in epilepsy.

Published in:

Epilepsia (Series 4), 2015, v. 56, n. 4, p. 505, doi. 10.1111/epi.12939

By:

Lillis, Kyle P.;
Dulla, Chris;
Maheshwari, Atul;
Coulter, Douglas;
Mody, Istvan;
Heinemann, Uwe;
Armbruster, Moritz;
Žiburkus, Jokūbas

Publication type:

Article

Blood-brain barrier dysfunction can contribute to pharmacoresistance of seizures.

Published in:

Epilepsia (Series 4), 2014, v. 55, n. 8, p. 1255, doi. 10.1111/epi.12713

By:

Salar, Seda;
Maslarova, Anna;
Lippmann, Kristina;
Nichtweiss, Julia;
Weissberg, Itai;
Sheintuch, Liron;
Kunz, Wolfram S.;
Shorer, Zamir;
Friedman, Alon;
Heinemann, Uwe

Publication type:

Article

Mechanisms underlying blood-brain barrier dysfunction in brain pathology and epileptogenesis: Role of astroglia.

Published in:

Epilepsia (Series 4), 2012, v. 53, p. 53, doi. 10.1111/j.1528-1167.2012.03703.x

By:

Kovács, Richard;
Heinemann, Uwe;
Steinhäuser, Christian

Publication type:

Article

Primary afterdischarge in organotypic hippocampal slice cultures: Effects of standard antiepileptic drugs.

Published in:

Epilepsia (Series 4), 2012, v. 53, n. 11, p. 1928, doi. 10.1111/j.1528-1167.2012.03597.x

By:

Albus, Klaus;
Wahab, Abdul;
Heinemann, Uwe

Publication type:

Article

Extracellular ATP differentially affects epileptiform activity via purinergic P2X7 and adenosine A1 receptors in naive and chronic epileptic rats.

Published in:

Epilepsia (Series 4), 2012, v. 53, n. 11, p. 1978, doi. 10.1111/j.1528-1167.2012.03724.x

By:

Klaft, Zin-Juan;
Schulz, Steffen B.;
Maslarova, Anna;
Gabriel, Siegrun;
Heinemann, Uwe;
Gerevich, Zoltan

Publication type:

Article

RNA editing of Kv1.1 channels may account for reduced ictogenic potential of 4-aminopyridine in chronic epileptic rats.

Published in:

Epilepsia (Series 4), 2011, v. 52, n. 3, p. 645, doi. 10.1111/j.1528-1167.2011.02986.x

By:

Streit, Anne Kathrin;
Derst, Christian;
Wegner, Sven;
Heinemann, Uwe;
Zahn, Robert K.;
Decher, Niels

Publication type:

Article

Age- and region-specific effects of anticonvulsants and bumetanide on 4-aminopyridine-induced seizure-like events in immature rat hippocampal-entorhinal cortex slices.

Published in:

Epilepsia (Series 4), 2011, v. 52, n. 1, p. 94, doi. 10.1111/j.1528-1167.2010.02722.x

By:

Wahab, Abdul;
Albus, Klaus;
Heinemann, Uwe

Publication type:

Article

Role of blood-brain barrier injury in epileptogenesis.

Published in:

Epilepsia (Series 4), 2010, v. 51, p. 34, doi. 10.1111/j.1528-1167.2010.02820.x

By:

Friedman, Alon;
Heinemann, Uwe

Publication type:

Article

In search of models of pharmacoresistant epilepsy.

Published in:

Epilepsia (Series 4), 2010, v. 51, p. 154, doi. 10.1111/j.1528-1167.2010.02632.x

By:

Wahab, Abdul;
Albus, Klaus;
Gabriel, Siegrun;
Heinemann, Uwe

Publication type:

Article

Glutamine induces epileptiform discharges in superficial layers of the medial entorhinal cortex from pilocarpine-treated chronic epileptic rats in vitro.

Published in:

Epilepsia (Series 4), 2009, v. 50, n. 4, p. 849, doi. 10.1111/j.1528-1167.2008.01973.x

By:

Sandow, Nora;
Zahn, Robert K.;
Gabriel, Siegrun;
Heinemann, Uwe;
Lehmann, Thomas-Nicolas

Publication type:

Article

Cholinergic Dysfunction in Temporal Lobe Epilepsy.

Published in:

Epilepsia (Series 4), 2007, v. 48, p. 126, doi. 10.1111/j.1528-1167.2007.01300.x

By:

Friedman, Alon;
Behrens, Christoph J.;
Heinemann, Uwe

Publication type:

Article

The Subiculum: A Potential Site of Ictogenesis in Human Temporal Lobe Epilepsy.

Published in:

Epilepsia (Series 4), 2005, v. 46, p. 17, doi. 10.1111/j.1528-1167.2005.01066.x

By:

Wozny, Christian;
Knopp, Andreas;
Lehmann, Thomas-Nicolas;
Heinemann, Uwe;
Behr, Joachim

Publication type:

Article

Electrical and Chemical Long-term Depression Do Not Attenuate Low-Mg2+–induced Epileptiform Activity in the Entorhinal Cortex.

Published in:

Epilepsia (Series 4), 2005, v. 46, n. 4, p. 509, doi. 10.1111/j.0013-9580.2005.41204.x

By:

Solger, Jörg;
Heinemann, Uwe;
Behr, Joachim

Publication type:

Article

Persistent increase in ventral hippocampal long‐term potentiation by juvenile stress: A role for astrocytic glutamine synthetase.

Published in:

Glia (0894-1491), 2019, v. 67, n. 12, p. 2279, doi. 10.1002/glia.23683

By:

Ivens, Sebastian;
Çalışkan, Gürsel;
Papageorgiou, Ismini;
Cesetti, Tiziana;
Malich, Ansgar;
Kann, Oliver;
Heinemann, Uwe;
Stork, Oliver;
Albrecht, Anne

Publication type:

Article

Astrocytic glutamine synthetase is expressed in the neuronal somatic layers and down‐regulated proportionally to neuronal loss in the human epileptic hippocampus.

Published in:

Glia (0894-1491), 2018, v. 66, n. 5, p. 920, doi. 10.1002/glia.23292

By:

Papageorgiou, Ismini E.;
Valous, Nektarios A.;
Lahrmann, Bernd;
Janova, Hana;
Klaft, Zin‐Juan;
Koch, Arend;
Schneider, Ulf C.;
Vajkoczy, Peter;
Heppner, Frank L.;
Grabe, Niels;
Halama, Niels;
Heinemann, Uwe;
Kann, Oliver

Publication type:

Article

Shifts in excitatory/inhibitory balance by juvenile stress: A role for neuron-astrocyte interaction in the dentate gyrus.

Published in:

Glia (0894-1491), 2016, v. 64, n. 6, p. 911, doi. 10.1002/glia.22970

By:

Albrecht, Anne;
Ivens, Sebastian;
Papageorgiou, Ismini E.;
Çalışkan, Gürsel;
Saiepour, Nasrin;
Brück, Wolfgang;
Richter‐Levin, Gal;
Heinemann, Uwe;
Stork, Oliver

Publication type:

Article

Blood-brain barrier dysfunction, TGFβ signaling, and astrocyte dysfunction in epilepsy.

Published in:

Glia (0894-1491), 2012, v. 60, n. 8, p. 1251, doi. 10.1002/glia.22311

By:

Heinemann, Uwe;
Kaufer, Daniela;
Friedman, Alon

Publication type:

Article

Redistribution of astrocytic glutamine synthetase in the hippocampus of chronic epileptic rats.

Published in:

Glia (0894-1491), 2011, v. 59, n. 11, p. 1706, doi. 10.1002/glia.21217

By:

Papageorgiou, Ismini E.;
Gabriel, Siegrun;
Fetani, Andriani F.;
Kann, Oliver;
Heinemann, Uwe

Publication type:

Article

Impact of aquaporin-4 channels on K.

Published in:

Glia (0894-1491), 2011, v. 59, n. 6, p. 973, doi. 10.1002/glia.21169

By:

Strohschein, Susan;
Hüttmann, Kerstin;
Gabriel, Siegrun;
Binder, Devin K.;
Heinemann, Uwe;
Steinhäuser, Christian

Publication type:

Article

Low-frequency stimulation of the temporoammonic pathway induces heterosynaptic disinhibition in the subiculum.

Published in:

Hippocampus, 2011, v. 21, n. 7, p. 733, doi. 10.1002/hipo.20791

By:

Fidzinski, Pawel;
Wawra, Matthias;
Dugladze, Tamar;
Gloveli, Tengis;
Heinemann, Uwe;
Behr, Joachim

Publication type:

Article

Monoamines block kainate- and carbachol-induced γ-oscillations but augment stimulus-induced γ-oscillations in rat hippocampus in vitro.

Published in:

Hippocampus, 2009, v. 19, n. 3, p. 273, doi. 10.1002/hipo.20508

By:

Wójtowicz, Anna Maria;
van den Boom, Leander;
Chakrabarty, Arnab;
Maggio, Nicola;
Haq, Rizwan ul;
Behrens, Christoph J.;
Heinemann, Uwe

Publication type:

Article

A single application of MK801 causes symptoms of acute psychosis, deficits in spatial memory, and impairment of synaptic plasticity in rats.

Published in:

Hippocampus, 2008, v. 18, n. 2, p. 125, doi. 10.1002/hipo.20367

By:

Manahan-Vaughan, Denise;
von Haebler, Dorothea;
Winter, Christine;
Juckel, Georg;
Heinemann, Uwe

Publication type:

Article

Intrinsic theta-frequency membrane potential oscillations in layer III/V perirhinal cortex neurons of the rat.

Published in:

Hippocampus, 1999, v. 9, n. 5, p. 510, doi. 10.1002/(SICI)1098-1063(1999)9:5<510::AID-HIPO4>3.0.CO;2-9

By:

Bilkey, David K.;
Heinemann, Uwe

Publication type:

Article

Perforant path connections to area CA1 are predominantly inhibitory in the rat hippocampal-entorhinal cortex combined slice preparation.

Published in:

Hippocampus, 1995, v. 5, n. 2, p. 104, doi. 10.1002/hipo.450050203

By:

Empson, Ruth M.;
Heinemann, Uwe

Publication type:

Article

Effects of anticonvulsant drugs on hippocampal neurons.

Published in:

Hippocampus, 1994, v. 4, n. 3, p. 291, doi. 10.1002/hipo.450040312

By:

Heinemann, Uwe;
Dreier, Jens;
Leschinger, Andreas;
Stabel, Jasmine;
Draguhn, Andreas;
Zhang, Chuanli

Publication type:

Article

Entorhinal cortex-hippocampal interactions in normal and epileptic temporal lobe.

Published in:

Hippocampus, 1993, v. 3, p. 89, doi. 10.1002/hipo.1993.4500030712

By:

Heinemann, Uwe;
Li Zhang, Chuan;
Eder, Claudia

Publication type:

Article

Structural correlates and cellular mechanisms in entorhinal-hippocampal dysfunction.

Published in:

Hippocampus, 1993, v. 3, p. 293, doi. 10.1002/hipo.1993.4500030732

By:

Arne Schousboe;
Bachevalier, Jocelyne;
Braak, Heiko;
Heinemann, Uwe;
Nitsch, Robert;
Schröder, Hannsjörg;
Wetmore, Cynthia

Publication type:

Article

Tracing of axonal connections by rhodamine-dextran-amine in the rat hippocampal-entorhinal cortex slice preparation.

Published in:

Hippocampus, 1992, v. 2, n. 2, p. 99, doi. 10.1002/hipo.450020203

By:

Boulton, Carolyn L.;
v. Haebler, Dorothea;
Heinemann, Uwe

Publication type:

Article

Early adenosine release contributes to hypoxia-induced disruption of stimulus-induced sharp wave-ripple complexes in rat hippocampal area CA3.

Published in:

European Journal of Neuroscience, 2015, v. 42, n. 2, p. 1808, doi. 10.1111/ejn.12941

By:

Jarosch, Marlene S.;
Gebhardt, Christine;
Fano, Silvia;
Huchzermeyer, Christine;
ul Haq, Rizwan;
Behrens, Christoph J.;
Heinemann, Uwe

Publication type:

Article

Corticosterone and corticotropin-releasing factor acutely facilitate gamma oscillations in the hippocampus in vitro.

Published in:

European Journal of Neuroscience, 2015, v. 41, n. 1, p. 31, doi. 10.1111/ejn.12750

By:

Çalışkan, Gürsel;
Schulz, Steffen B.;
Gruber, David;
Behr, Joachim;
Heinemann, Uwe;
Gerevich, Zoltan

Publication type:

Article

Differential effects of blockade of ERG channels on gamma oscillations and excitability in rat hippocampal slices.

Published in:

European Journal of Neuroscience, 2012, v. 36, n. 12, p. 3628, doi. 10.1111/ejn.12015

By:

Fano, Silvia;
Çalışkan, Gürsel;
Heinemann, Uwe

Publication type:

Article

Fluoxetine induces vasodilatation of cerebral arterioles by co-modulating NO/muscarinic signalling.

Published in:

Journal of Cellular & Molecular Medicine, 2012, v. 16, n. 11, p. 2736, doi. 10.1111/j.1582-4934.2012.01596.x

By:

Ofek, Keren;
Schoknecht, Karl;
Melamed-Book, Naomi;
Heinemann, Uwe;
Friedman, Alon;
Soreq, Hermona

Publication type:

Article

The Impact of Astrocytic Gap Junctional Coupling on Potassium Buffering in the Hippocampus.

Published in:

Journal of Neuroscience, 2006, v. 26, n. 20, p. 5438, doi. 10.1523/JNEUROSCI.0037-06.2006

By:

Wallraff, Anke;
Köhling, Rüdiger;
Heinemann, Uwe;
Theis, Martin;
Willecke, Klaus;
Steinhäuser, Christian

Publication type:

Article

Mitochondrial Calcium Ion and Membrane Potential Transients Follow the Pattern of Epileptiform Discharges in Hippocampal Slice Cultures.

Published in:

Journal of Neuroscience, 2005, v. 25, n. 17, p. 4260, doi. 10.1523/JNEUROSCI.4000-04.2005

By:

Kovács, Richard;
Kardos, Julianna;
Heinemann, Uwe;
Kann, Oliver

Publication type:

Article

Stimulus and Potassium-Induced Epileptiform Activity in the Human Dentate Gyrus from Patients with and without Hippocampal Sclerosis.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 46, p. 10416, doi. 10.1523/JNEUROSCI.2074-04.2004

By:

Gabriel, Siegrun;
Njunting, Marleisje;
Pomper, Joern K.;
Eilers, Alexander;
Kivi, Anatol;
Zeller, Melanie;
Heinemann, Uwe;
Merschhemke, Martin;
Meencke, Heinz-Joachim;
Sanabria, Emilio R.G.;
Cavalheiro, Esper A.;
Lehmann, Thomas-Nicolas

Publication type:

Article

Lasting Blood-Brain Barrier Disruption Induces Epileptic Focus in the Rat Somatosensory Cortex.

Published in:

Journal of Neuroscience, 2004, v. 24, n. 36, p. 7829, doi. 10.1523/JNEUROSCI.1751-04.2004

By:

Seiffert, Ernst;
Dreier, Jens P.;
Ivens, Sebastian;
Bechmann, Ingo;
Tomkins, Oren;
Heinemann, Uwe;
Friedman, Alon

Publication type:

Article

Accelerated Hippocampal Spreading Depression and Enhanced Locomotory Activity in Mice With Astrocyte-Directed Inactivation of Connexin43.

Published in:

Journal of Neuroscience, 2003, v. 23, n. 3, p. 766, doi. 10.1523/JNEUROSCI.23-03-00766.2003

By:

Theis, Martin;
Jauch, Regina;
Lang Zhuo;
Speidel, Dina;
Wallraff, Anke;
Doring, Britta;
Frisch, Christian;
Sohl, Goran;
Teubner, Barbara;
Euwens, Carsten;
Huston, Joseph;
Steinhauser, Christian;
Messing, Albee;
Heinemann, Uwe;
Willecke, Klaus

Publication type:

Article

A novel mechanism underlying drug resistance in chronic epilepsy.

Published in:

Annals of Neurology, 2003, v. 53, n. 4, p. 469

By:

Stefan Remy;
Siegrun Gabriel;
Bernd W. Urban;
Dirk Dietrich;
Thomas N. Lehmann;
Christian E. Elger;
Uwe Heinemann;
Heinz Beck

Publication type:

Article

Persistent BBB disruption may underlie alpha interferon-induced seizures.

Published in:

Journal of Neurology, 2005, v. 252, n. 1, p. 42, doi. 10.1007/s00415-005-0596-3

By:

Pavlovsky, Lev;
Seiffert, Ernst;
Heinemann, Uwe;
Korn, Akiva;
Golan, Haim;
Friedman, Alon

Publication type:

Article

Long-Lasting Increase of Corticosterone After Fear Memory Reactivation: Anxiolytic Effects and Network Activity Modulation in the Ventral Hippocampus.

Published in:

Neuropsychopharmacology, 2013, v. 38, n. 3, p. 386, doi. 10.1038/npp.2012.192

By:

Albrecht, Anne;
Çalışkan, Gürsel;
Oitzl, Melly S;
Heinemann, Uwe;
Stork, Oliver

Publication type:

Article

Blood-Brain Barrier Dysfunction in Epileptogenesis of the Temporal Lobe.

Published in:

Epilepsy Research & Treatment, 2011, p. 1, doi. 10.1155/2011/143908

By:

Weissberg, Itai;
Reichert, Aljoscha;
Heinemann, Uwe;
Friedman, Alon

Publication type:

Article

New dangers of anesthesia: isoflurane induced opening of the blood–brain barrier (Commentary on Tétrault et al.).

Published in:

European Journal of Neuroscience, 2008, v. 28, n. 7, p. 1329, doi. 10.1111/j.1460-9568.2008.06500.x

By:

Heinemann, Uwe

Publication type:

Article

Acetylcholine-induced seizure-like activity and modified cholinergic gene expression in chronically epileptic rats.

Published in:

2008

By:

Zimmerman, Gabriel;
Njunting, Marleisje;
Ivens, Sebastian;
Tolner, Else A.;
Behrens, Christoph J.;
Gross, Miriam;
Soreq, Hermona;
Heinemann, Uwe;
Friedman, Alon

Publication type:

Correction Notice

Acetylcholine-induced seizure-like activity and modified cholinergic gene expression in chronically epileptic rats.

Published in:

European Journal of Neuroscience, 2008, v. 27, n. 4, p. 965, doi. 10.1111/j.1460-9568.2008.06070.x

By:

Zimmerman, Gabriel;
Njunting, Marleisje;
Ivens, Sebastian;
Tolner, Elsa;
Behrens, Christoph J.;
Gross, Miriam;
Soreq, Hermona;
Heinemann, Uwe;
Friedman, Alon

Publication type:

Article