Works by Heine, Holger
Results: 47
Lipid A Mimetics Based on Unnatural Disaccharide Scaffold as Potent TLR4 Agonists for Prospective Immunotherapeutics and Adjuvants.
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- Chemistry - A European Journal, 2022, v. 28, n. 35, p. 1, doi. 10.1002/chem.202200547
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- Article
Nonreducing Sugar Scaffold Enables the Development of Immunomodulatory TLR4‐specific LPS Mimetics with Picomolar Potency.
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- Angewandte Chemie, 2024, v. 136, n. 39, p. 1, doi. 10.1002/ange.202408421
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- Article
Lipophilic Allergens, Different Modes of Allergen-Lipid Interaction and Their Impact on Asthma and Allergy.
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- Frontiers in Immunology, 2019, p. N.PAG, doi. 10.3389/fimmu.2019.00122
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- Article
The Human-Associated Archaeon Methanosphaera stadtmanae Is Recognized through Its RNA and Induces TLR8-Dependent NLRP3 Inflammasome Activation.
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- Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.01535
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- Article
Recurrent Phases of Strict Protein Limitation Inhibit Tumor Growth and Restore Lifespan in A Drosophila Intestinal Cancer Model.
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- Aging & Disease, 2024, v. 15, n. 1, p. 226, doi. 10.14336/AD.2023.0517
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- Article
Accumulation of Inhibitory κB-α as a Mechanism Contributing to the Anti-Inflammatory Effects of Surfactant Protein-A.
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- American Journal of Respiratory Cell & Molecular Biology, 2004, v. 31, n. 6, p. 587, doi. 10.1165/rcmb.2004-0003OC
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- Article
Nonreducing Sugar Scaffold Enables the Development of Immunomodulatory TLR4‐specific LPS Mimetics with Picomolar Potency.
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- Angewandte Chemie International Edition, 2024, v. 63, n. 39, p. 1, doi. 10.1002/anie.202408421
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- Article
The structure of the extracellular teichoic acids from the allergy-protective bacterium Lactococcus lactis G121.
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- Biological Chemistry, 2012, v. 393, n. 8, p. 749, doi. 10.1515/hsz-2012-0142
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- Article
Cytokine-inducing lipoteichoic acids of the allergy-protective bacterium Lactococcus lactis G121 do not activate via Toll-like receptor 2.
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- Glycobiology, 2011, v. 21, n. 12, p. 1588, doi. 10.1093/glycob/cwr071
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- Article
Driver Mutations in Major Lung Cancer Oncogenes Can Be Analyzed in Drosophila Models.
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- Altex, 2021, v. 38, n. 2, p. 235, doi. 10.14573/altex.1912131
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- Article
Role of the Toll-Like Receptor 4 in Neuroinflammation in Alzheimer’s Disease.
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- Cellular Physiology & Biochemistry (Karger AG), 2007, v. 20, n. 6, p. 947, doi. 10.1159/000110455
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- Article
Lipoproteins/peptides are sepsis-inducing toxins from bacteria that can be neutralized by synthetic anti-endotoxin peptides.
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- Scientific Reports, 2015, p. 14292, doi. 10.1038/srep14292
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- Article
Immunogenic properties of the human gut-associated archaeon Methanomassiliicoccus luminyensis and its susceptibility to antimicrobial peptides.
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- PLoS ONE, 2017, v. 12, n. 10, p. 1, doi. 10.1371/journal.pone.0185919
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- Article
Disaccharide‐Based Anionic Amphiphiles as Potent Inhibitors of Lipopolysaccharide‐Induced Inflammation.
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- ChemMedChem, 2018, v. 13, n. 21, p. 2317, doi. 10.1002/cmdc.201800505
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- Article
RNA is taking its Toll: Impact of RNA‐specific Toll‐like receptors on health and disease.
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- Allergy, 2019, v. 74, n. 2, p. 223, doi. 10.1111/all.13680
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- Article
The Lipid A from the Lipopolysaccharide of the Phototrophic Bacterium Rhodomicrobium vannielii ATCC 17100 Revisited.
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- International Journal of Molecular Sciences, 2021, v. 22, n. 1, p. 258, doi. 10.3390/ijms22010258
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- Article
Isolation of Enterococcus faecium NM113, Enterococcus faecium NM213 and Lactobacillus casei NM512 as novel probiotics with immunomodulatory properties.
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- Microbiology & Immunology, 2014, v. 58, n. 10, p. 559, doi. 10.1111/1348-0421.12187
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- Article
Exploring Species-Specificity in TLR4/MD-2 Inhibition with Amphiphilic Lipid A Mimicking Glycolipids.
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- Molecules, 2023, v. 28, n. 16, p. 5948, doi. 10.3390/molecules28165948
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- Article
Therapeutic Targeting of TLR4 for Inflammation, Infection, and Cancer: A Perspective for Disaccharide Lipid A Mimetics.
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- Pharmaceuticals (14248247), 2023, v. 16, n. 1, p. 23, doi. 10.3390/ph16010023
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- Article
Anti-endotoxic activity and structural basis for human MD-2·TLR4 antagonism of tetraacylated lipid A mimetics based on βGlcN(1↔1)αGlcN scaffold.
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- Innate Immunity, 2015, v. 21, n. 5, p. 490, doi. 10.1177/1753425914550426
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- Article
Immunization with an anti-idiotypic antibody against the broadly lipopolysaccharide-reactive antibody WN1 222-5 induces Escherichia coli R3-core-type specific antibodies in rabbits.
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- Innate Immunity, 2012, v. 18, n. 2, p. 279, doi. 10.1177/1753425911401055
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- Article
Investigation on the agonistic and antagonistic biological activities of synthetic Chlamydia lipid A and its use in in vitro enzymatic assays.
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- Innate Immunity, 2007, v. 13, n. 2, p. 126, doi. 10.1177/0968051907079122
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- Article
Structural and biological characterization of highly purified hepta-acyl lipid A present in the lipopolysaccharide of the Salmonella enterica sv. Minnesota Re deep rough mutant strain R595.
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- Innate Immunity, 2002, v. 8, n. 5, p. 343, doi. 10.1177/09680519020080050801
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- Article
Endotoxin-like properties of a rhamnolipid exotoxin from Burkholderia ( Pseudomonas) plantarii: immune cell stimulation and biophysical characterization.
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- Biological Chemistry, 2006, v. 387, n. 3, p. 301, doi. 10.1515/BC.2006.040
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- Article
Investigating pyroptosis as a mechanism of L. major cell‐to‐cell spread in the human BLaER1 infection model.
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- Molecular Microbiology, 2024, v. 121, n. 3, p. 453, doi. 10.1111/mmi.15142
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- Article
Binding of lipopeptide to CD14 induces physical proximity of CD14, TLR2 and TLR1.
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- European Journal of Immunology, 2005, v. 35, n. 3, p. 911, doi. 10.1002/eji.200425336
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- Article
Toll-like receptor 6-independent signaling by diacylated lipopeptides.
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- European Journal of Immunology, 2005, v. 35, n. 1, p. 282, doi. 10.1002/eji.200424955
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- Article
The generalized endotoxic principle.
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- European Journal of Immunology, 2003, v. 33, n. 6, p. 1586, doi. 10.1002/eji.200323649
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- Article
CD55/decay accelerating factor is part of the lipopolysaccharide-induced receptor complex.
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- European Journal of Immunology, 2003, v. 33, n. 5, p. 1399, doi. 10.1002/eji.200323381
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- Article
Lipopolysaccharide and ceramide docking to CD14 provokes ligand-specific receptor clustering in rafts.
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- European Journal of Immunology, 2001, v. 31, n. 11, p. 3153, doi. 10.1002/1521-4141(200111)31:11<3153::AID-IMMU3153>3.0.CO;2-0
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- Article
Neutrophil extracellular trap-associated RNA and LL37 enable self-amplifying inflammation in psoriasis.
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- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-019-13756-4
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- Article
Regulators of G-protein signalling are modulated by bacterial lipopeptides and lipopolysaccharide.
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- FEBS Journal, 2009, v. 276, n. 3, p. 649, doi. 10.1111/j.1742-4658.2008.06813.x
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- Article
Lipopeptide structure determines TLR2 dependent cell activation level.
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- FEBS Journal, 2005, v. 272, n. 24, p. 6354, doi. 10.1111/j.1742-4658.2005.05029.x
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- Article
Total Synthesis of Five Lipoteichoic acids of Clostridium difficile.
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- Chemistry - A European Journal, 2014, v. 20, n. 42, p. 13511, doi. 10.1002/chem.201404336
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- Article
Allergy protection by cowshed bacteria - recent findings and future prospects.
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- Pediatric Allergy & Immunology, 2016, v. 27, n. 4, p. 340, doi. 10.1111/pai.12559
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- Article
TLR4-mediated inflammatory activation of human coronary artery endothelial cells by LPS
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- Cardiovascular Research, 2002, v. 56, n. 1, p. 126, doi. 10.1016/S0008-6363(02)00512-6
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- Article
Structural and Immunochemical Analysis of the Lipopolysaccharide from Acinetobacter lwoffii F78 Located Outside Chlamydiaceae with a Chlamydia-Specific Lipopolysaccharide Epitope.
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- Chemistry - A European Journal, 2008, v. 14, n. 33, p. 10251, doi. 10.1002/chem.200800958
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- Article
Tailored Modulation of Cellular Pro-inflammatory Responses With Disaccharide Lipid A Mimetics.
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- Frontiers in Immunology, 2021, v. 11, p. N.PAG, doi. 10.3389/fimmu.2021.631797
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- Article
Corrigendum: Lipopolysaccharide Recognition in the Crossroads of TLR4 and Caspase-4/11 Mediated Inflammatory Pathways.
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- 2021
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- Correction Notice
Lipopolysaccharide Recognition in the Crossroads of TLR4 and Caspase-4/11 Mediated Inflammatory Pathways.
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- Frontiers in Immunology, 2020, v. 11, p. N.PAG, doi. 10.3389/fimmu.2020.585146
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- Article
Salmonella enterica serovar Typhimurium ΔmsbB Triggers Exacerbated Inflammation in Nod2 Deficient Mice.
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- PLoS ONE, 2014, v. 9, n. 11, p. 1, doi. 10.1371/journal.pone.0113645
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- Article
The Intestinal Archaea <i>Methanosphaera stadtmanae</i> and <i>Methanobrevibacter smithii</i> Activate Human Dendritic Cells.
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- PLoS ONE, 2014, v. 9, n. 6, p. 1, doi. 10.1371/journal.pone.0099411
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- Article
Histone Deacetylase (HDAC) 1 Controls the Expression of Beta Defensin 1 in Human Lung Epithelial Cells.
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- PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0050000
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- Article
Increased Expression of Beta-Defensin 1 (DEFB1) in Chronic Obstructive Pulmonary Disease.
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- PLoS ONE, 2011, v. 6, n. 7, p. 1, doi. 10.1371/journal.pone.0021898
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- Article
Dynamic Fluctuations of Protein-Carbohydrate Interactions Promote Protein Aggregation.
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- PLoS ONE, 2009, v. 4, n. 12, p. 1, doi. 10.1371/journal.pone.0008425
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- Article
Biological effects of carbon black nanoparticles are changed by surface coating with polycyclic aromatic hydrocarbons.
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- Particle & Fibre Toxicology, 2017, v. 14, p. 1, doi. 10.1186/s12989-017-0189-1
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- Article
S100A7/psoriasin expression in the human lung: unchanged in patients with COPD, but upregulated upon positive S. aureus detection.
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- BMC Pulmonary Medicine, 2011, v. 11, n. 1, p. 10, doi. 10.1186/1471-2466-11-10
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- Article