Works by Hehn, Alain

Results: 39

Fingerprinting and chemotyping approaches reveal a wide genetic and metabolic diversity among wild hops (Humulus lupulus L.).

Published in:

PLoS ONE, 2025, v. 20, n. 5, p. 1, doi. 10.1371/journal.pone.0322330

By:

Ducrocq, Florent;
Piutti, Séverine;
Henychová, Alena;
Villerd, Jean;
Laflotte, Alexandre;
Girardeau, Loïc;
Grosjean, Jérémy;
Patzak, Josef;
Hehn, Alain

Publication type:

Article

A Rapid and Efficient Method for Isolating High Quality DNA from Leaves of Carnivorous Plants from the Drosera Genus.

Published in:

Molecular Biotechnology, 2012, v. 51, n. 3, p. 247, doi. 10.1007/s12033-011-9462-y

By:

Biteau, Flore;
Nisse, Estelle;
Hehn, Alain;
Miguel, Sissi;
Hannewald, Paul;
Bourgaud, Frédéric

Publication type:

Article

Identification and Quantification of Coumarins by UHPLC-MS in Arabidopsis thaliana Natural Populations.

Published in:

Molecules, 2021, v. 26, n. 6, p. 1804, doi. 10.3390/molecules26061804

By:

Perkowska, Izabela;
Siwinska, Joanna;
Olry, Alexandre;
Grosjean, Jérémy;
Hehn, Alain;
Bourgaud, Frédéric;
Lojkowska, Ewa;
Ihnatowicz, Anna;
Matos, Maria João

Publication type:

Article

In vitro plant regeneration and Agrobacterium-mediated genetic transformation of a carnivorous plant, Nepenthes mirabilis.

Published in:

Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-74108-7

By:

Miguel, Sissi;
Michel, Cindy;
Biteau, Flore;
Hehn, Alain;
Bourgaud, Frédéric

Publication type:

Article

A SIMPLE SDS-PAGE PROTEIN PATTERN FROM PITCHER SECRETIONS AS A NEW TOOL TO DISTINGUISH NEPENTHES SPECIES (NEPENTHACEAE).

Published in:

American Journal of Botany, 2013, v. 100, n. 12, p. 2478, doi. 10.3732/ajb.1300145

By:

Biteau, Flore;
Nisse, Estelle;
Miguel, Sissi;
Hannewald, Paul;
Bazile, Vincent;
Gaume, Laurence;
Mignard, Benoit;
Hehn, Alain;
Bourgaud, Frederic

Publication type:

Article

Evolution of substrate recognition sites (SRSs) in cytochromes P450 from Apiaceae exemplified by the CYP71AJ subfamily.

Published in:

BMC Evolutionary Biology, 2015, v. 15, n. 1, p. 1, doi. 10.1186/s12862-015-0396-z

By:

Dueholm, Bjørn;
Krieger, Célia;
Drew, Damian;
Olry, Alexandre;
Tsunashi Kamo;
Taboureau, Olivier;
Weitzel, Corinna;
Bourgaud, Frédéric;
Hehn, Alain;
Toft Simonsen, Henrik

Publication type:

Article

Evolution of substrate recognition sites (SRSs) in cytochromes P450 from Apiaceae exemplified by the CYP71AJ subfamily

Published in:

BMC Evolutionary Biology, 2015, v. 15, n. 1, p. 122, doi. 10.1186/s12862-015-0396-z

By:

Dueholm, Bjørn;
Krieger, Célia;
Drew, Damian;
Olry, Alexandre;
Kamo, Tsunashi;
Taboureau, Olivier;
Weitzel, Corinna;
Bourgaud, Frédéric;
Hehn, Alain;
Simonsen, Henrik Toft

Publication type:

Article

Tropane alkaloid profiling of hydroponic Datura innoxia mill. Plants inoculated with Agrobacterium rhizogenes.

Published in:

Phytochemical Analysis, 2010, v. 21, n. 1, p. 118, doi. 10.1002/pca.1180

By:

Jousse, Cyril;
Vu, Thi Dao;
Le Minh Tran, Thi;
Al Balkhi, Mohamad Houssam;
Molinié, Roland;
Boitel-Conti, Michèle;
Pilard, Serge;
Mathiron, David;
Hehn, Alain;
Bourgaud, Frédéric;
Gontier, Eric

Publication type:

Article

Defence mechanisms of Ficus: pyramiding strategies to cope with pests and pathogens.

Published in:

Planta: An International Journal of Plant Biology, 2019, v. 249, n. 3, p. 617, doi. 10.1007/s00425-019-03098-2

By:

Villard, Cloé;
Larbat, Romain;
Munakata, Ryosuke;
Hehn, Alain

Publication type:

Article

Beet western yellows virus infects the carnivorous plant Nepenthes mirabilis.

Published in:

2016

By:

Miguel, Sissi;
Biteau, Flore;
Mignard, Benoit;
Marais, Armelle;
Candresse, Thierry;
Theil, Sébastien;
Bourgaud, Frédéric;
Hehn, Alain

Publication type:

Report

Assessing Carnivorous Plants for the Production of Recombinant Proteins.

Published in:

Frontiers in Plant Science, 2019, p. N.PAG, doi. 10.3389/fpls.2019.00793

By:

Miguel, Sissi;
Nisse, Estelle;
Biteau, Flore;
Rottloff, Sandy;
Mignard, Benoit;
Gontier, Eric;
Hehn, Alain;
Bourgaud, Frédéric

Publication type:

Article

The CYP71AZ P450 Subfamily: A Driving Factor for the Diversification of Coumarin Biosynthesis in Apiaceous Plants.

Published in:

Frontiers in Plant Science, 2018, p. N.PAG, doi. 10.3389/fpls.2018.00820

By:

Krieger, Célia;
Roselli, Sandro;
Kellner-Thielmann, Sandra;
Galati, Gianni;
Schneider, Bernd;
Grosjean, Jérémy;
Olry, Alexandre;
Ritchie, David;
Matern, Ulrich;
Bourgaud, Frédéric;
Hehn, Alain

Publication type:

Article

Catalytic mechanism underlying the regiospecificity of coumarin-substrate transmembrane prenyltransferases in Apiaceae.

Published in:

Plant & Cell Physiology, 2025, v. 66, n. 1, p. 1, doi. 10.1093/pcp/pcae134

By:

Han, Junwen;
Munakata, Ryosuke;
Takahashi, Hironobu;
Koeduka, Takao;
Kubota, Mayumi;
Moriyoshi, Eiko;
Hehn, Alain;
Sugiyama, Akifumi;
Yazaki, Kazufumi

Publication type:

Article

Lineage‐specific patterns in the Moraceae family allow identification of convergent P450 enzymes involved in furanocoumarin biosynthesis.

Published in:

New Phytologist, 2025, v. 245, n. 5, p. 2085, doi. 10.1111/nph.20381

By:

Bouillé, Alexandre;
Larbat, Romain;
Kumari, Rashmi;
Olry, Alexandre;
Charles, Clément;
Nelson, David R.;
Thornton, Janet;
Villard, Cloé;
Hehn, Alain

Publication type:

Article

Proteome analysis of digestive fluids in Nepenthes pitchers.

Published in:

Annals of Botany, 2016, v. 117, n. 3, p. 479, doi. 10.1093/aob/mcw001

By:

Rottloff, Sandy;
Miguel, Sissi;
Biteau, Flore;
Nisse, Estelle;
Hammann, Philippe;
Kuhn, Lauriane;
Chicher, Johana;
Bazile, Vincent;
Gaume, Laurence;
Mignard, Benoit;
Hehn, Alain;
Bourgaud, Frédéric

Publication type:

Article

Hop Extract Anti-Inflammatory Effect on Human Chondrocytes Is Potentiated When Encapsulated in Rapeseed Lecithin Nanoliposomes.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 20, p. 12423, doi. 10.3390/ijms232012423

By:

Velot, Émilie;
Ducrocq, Florent;
Girardeau, Loïc;
Hehn, Alain;
Piutti, Séverine;
Kahn, Cyril;
Linder, Michel;
Bianchi, Arnaud;
Arab-Tehrany, Elmira

Publication type:

Article

Molecular Identification of Endophytic Bacteria in Leucojum aestivum In Vitro Culture, NMR-Based Metabolomics Study and LC-MS Analysis Leading to Potential Amaryllidaceae Alkaloid Production.

Published in:

International Journal of Molecular Sciences, 2021, v. 22, n. 4, p. 1773, doi. 10.3390/ijms22041773

By:

Spina, Rosella;
Saliba, Sahar;
Dupire, François;
Ptak, Agata;
Hehn, Alain;
Piutti, Séverine;
Poinsignon, Sophie;
Leclerc, Sebastien;
Bouguet-Bonnet, Sabine;
Laurain-Mattar, Dominique;
Arraez-Roman, David

Publication type:

Article

Genes to specialized metabolites: accumulation of scopoletin, umbelliferone and their glycosides in natural populations of Arabidopsis thaliana.

Published in:

BMC Plant Biology, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12870-024-05491-w

By:

Ihnatowicz, Anna;
Siwinska, Joanna;
Perkowska, Izabela;
Grosjean, Jeremy;
Hehn, Alain;
Bourgaud, Frederic;
Lojkowska, Ewa;
Olry, Alexandre

Publication type:

Article

Untargeted Metabolomics Approach Reveals Diverse Responses of Pastinaca Sativa to Ozone and Wounding Stresses.

Published in:

Metabolites (2218-1989), 2019, v. 9, n. 7, p. 153, doi. 10.3390/metabo9070153

By:

Galati, Gianni;
Gandin, Anthony;
Jolivet, Yves;
Larbat, Romain;
Hehn, Alain

Publication type:

Article

Scopoletin 8-hydroxylase: a novel enzyme involved in coumarin biosynthesis and iron-deficiency responses in Arabidopsis.

Published in:

Journal of Experimental Botany, 2018, v. 69, n. 7, p. 1735, doi. 10.1093/jxb/ery005

By:

Siwinska, Joanna;
Siatkowska, Kinga;
Olry, Alexandre;
Grosjean, Jeremy;
Hehn, Alain;
Bourgaud, Frederic;
Meharg, Andrew A.;
Carey, Manus;
Lojkowska, Ewa;
Ihnatowicz, Anna

Publication type:

Article

Molecular Cloning and Characterization of a Geranyl Diphosphate-Specific Aromatic Prenyltransferase from Lemon.

Published in:

Plant Physiology, 2014, v. 166, n. 1, p. 80, doi. 10.1104/pp.114.246892

By:

Ryosuke Munakata;
Tsuyoshi Inoue;
Takao Koeduka;
Fazeelat Karamat;
Olry, Alexandre;
Akifumi Sugiyama;
Kojiro Takanashi;
Dugrand, Audray;
Froelicher, Yann;
Ryo Tanaka;
Yoshihiro Uto;
Hitoshi Hori;
Jun-Ichi Azuma;
Hehn, Alain;
Bourgaud, Frédéric;
Kazufumi Yazaki

Publication type:

Article

Author Correction: A GDSL lipase-like from Ipomoea batatas catalyzes efficient production of 3,5-diCQA when expressed in Pichia pastoris.

Published in:

2020

By:

Miguel, Sissi;
Legrand, Guillaume;
Duriot, Léonor;
Delporte, Marianne;
Menin, Barbara;
Michel, Cindy;
Olry, Alexandre;
Chataigné, Gabrielle;
Salwinski, Aleksander;
Bygdell, Joakim;
Vercaigne, Dominique;
Wingsle, Gunnar;
Hilbert, Jean Louis;
Bourgaud, Frédéric;
Hehn, Alain;
Gagneul, David

Publication type:

Correction Notice

A GDSL lipase-like from Ipomoea batatas catalyzes efficient production of 3,5-diCQA when expressed in Pichia pastoris.

Published in:

Communications Biology, 2020, v. 3, n. 1, p. 1, doi. 10.1038/s42003-020-01387-1

By:

Miguel, Sissi;
Legrand, Guillaume;
Duriot, Léonor;
Delporte, Marianne;
Menin, Barbara;
Michel, Cindy;
Olry, Alexandre;
Chataigné, Gabrielle;
Salwinski, Aleksander;
Bygdell, Joakim;
Vercaigne, Dominique;
Wingsle, Gunnar;
Hilbert, Jean Louis;
Bourgaud, Frédéric;
Hehn, Alain;
Gagneul, David

Publication type:

Article

Isolation of Artemisia capillaris membrane-bound di-prenyltransferase for phenylpropanoids and redesign of artepillin C in yeast.

Published in:

Communications Biology, 2019, v. 2, n. 1, p. N.PAG, doi. 10.1038/s42003-019-0630-0

By:

Munakata, Ryosuke;
Takemura, Tomoya;
Tatsumi, Kanade;
Moriyoshi, Eiko;
Yanagihara, Koki;
Sugiyama, Akifumi;
Suzuki, Hideyuki;
Seki, Hikaru;
Muranaka, Toshiya;
Kawano, Noriaki;
Yoshimatsu, Kayo;
Kawahara, Nobuo;
Yamaura, Takao;
Grosjean, Jérémy;
Bourgaud, Frédéric;
Hehn, Alain;
Yazaki, Kazufumi

Publication type:

Article

Screening of Endophytic Bacteria of Leucojum aestivum 'Gravety Giant' as a Potential Source of Alkaloids and as Antagonist to Some Plant Fungal Pathogens.

Published in:

Microorganisms, 2022, v. 10, n. 10, p. 2089, doi. 10.3390/microorganisms10102089

By:

Munakata, Yuka;
Spina, Rosella;
Slezack-Deschaumes, Sophie;
Genestier, Julie;
Hehn, Alain;
Laurain-Mattar, Dominique

Publication type:

Article

Screening of Antimicrobial Activities and Lipopeptide Production of Endophytic Bacteria Isolated from Vetiver Roots.

Published in:

Microorganisms, 2022, v. 10, n. 2, p. N.PAG, doi. 10.3390/microorganisms10020209

By:

Munakata, Yuka;
Heuson, Egon;
Daboudet, Théo;
Deracinois, Barbara;
Duban, Matthieu;
Hehn, Alain;
Coutte, François;
Slezack-Deschaumes, Sophie

Publication type:

Article

The Distribution of Coumarins and Furanocoumarins in Citrus Species Closely Matches Citrus Phylogeny and Reflects the Organization of Biosynthetic Pathways.

Published in:

PLoS ONE, 2015, v. 10, n. 10, p. 1, doi. 10.1371/journal.pone.0142757

By:

Dugrand-Judek, Audray;
Olry, Alexandre;
Hehn, Alain;
Costantino, Gilles;
Ollitrault, Patrick;
Froelicher, Yann;
Bourgaud, Frédéric

Publication type:

Article

Coexpression of CPR from Various Origins Enhances Biotransformation Activity of Human CYPs in S. pombe.

Published in:

Applied Biochemistry & Biotechnology, 2013, v. 170, n. 7, p. 1751, doi. 10.1007/s12010-013-0303-2

By:

Neunzig, Ina;
Widjaja, Maria;
Peters, Frank;
Maurer, Hans;
Hehn, Alain;
Bourgaud, Frédéric;
Bureik, Matthias

Publication type:

Article

A new P450 involved in the furanocoumarin pathway underlies a recent case of convergent evolution.

Published in:

New Phytologist, 2021, v. 231, n. 5, p. 1923, doi. 10.1111/nph.17458

By:

Villard, Cloé;
Munakata, Ryosuke;
Kitajima, Sakihito;
van Velzen, Robin;
Schranz, Michael Eric;
Larbat, Romain;
Hehn, Alain

Publication type:

Article

Convergent evolution of the UbiA prenyltransferase family underlies the independent acquisition of furanocoumarins in plants.

Published in:

New Phytologist, 2020, v. 225, n. 5, p. 2166, doi. 10.1111/nph.16277

By:

Munakata, Ryosuke;
Kitajima, Sakihito;
Nuttens, Andréïna;
Tatsumi, Kanade;
Takemura, Tomoya;
Ichino, Takuji;
Galati, Gianni;
Vautrin, Sonia;
Bergès, Hélène;
Grosjean, Jérémy;
Bourgaud, Frédéric;
Sugiyama, Akifumi;
Hehn, Alain;
Yazaki, Kazufumi

Publication type:

Article

Molecular evolution of parsnip ( Pastinaca sativa) membrane-bound prenyltransferases for linear and/or angular furanocoumarin biosynthesis.

Published in:

New Phytologist, 2016, v. 211, n. 1, p. 332, doi. 10.1111/nph.13899

By:

Munakata, Ryosuke;
Olry, Alexandre;
Karamat, Fazeelat;
Courdavault, Vincent;
Sugiyama, Akifumi;
Date, Yoshiaki;
Krieger, Célia;
Silie, Prisca;
Foureau, Emilien;
Papon, Nicolas;
Grosjean, Jérémy;
Yazaki, Kazufumi;
Bourgaud, Frédéric;
Hehn, Alain

Publication type:

Article

A bacterial artificial chromosome ( BAC) genomic approach reveals partial clustering of the furanocoumarin pathway genes in parsnip.

Published in:

Plant Journal, 2017, v. 89, n. 6, p. 1119, doi. 10.1111/tpj.13450

By:

Roselli, Sandro;
Olry, Alexandre;
Vautrin, Sonia;
Coriton, Olivier;
Ritchie, Dave;
Galati, Gianni;
Navrot, Nicolas;
Krieger, Célia;
Vialart, Guilhem;
Bergès, Hélène;
Bourgaud, Frédéric;
Hehn, Alain

Publication type:

Article

A coumarin-specific prenyltransferase catalyzes the crucial biosynthetic reaction for furanocoumarin formation in parsley.

Published in:

Plant Journal, 2014, v. 77, n. 4, p. 627, doi. 10.1111/tpj.12409

By:

Karamat, Fazeelat;
Olry, Alexandre;
Munakata, Ryosuke;
Koeduka, Takao;
Sugiyama, Akifumi;
Paris, Cedric;
Hehn, Alain;
Bourgaud, Frédéric;
Yazaki, Kazufumi

Publication type:

Article

A 2-oxoglutarate-dependent dioxygenase from Ruta graveolens L. exhibits p-coumaroyl CoA 2′-hydroxylase activity (C2′H): a missing step in the synthesis of umbelliferone in plants.

Published in:

Plant Journal, 2012, v. 70, n. 3, p. 460, doi. 10.1111/j.1365-313X.2011.04879.x

By:

Vialart, Guilhem;
Hehn, Alain;
Olry, Alexandre;
Ito, Kyoko;
Krieger, Celia;
Larbat, Romain;
Paris, Cedric;
Shimizu, Bun-ichi;
Sugimoto, Yukihiro;
Mizutani, Masaharu;
Bourgaud, Frederic

Publication type:

Article

Comparative study of the production of coumarins and furanocoumarins in three Ruteae species.

Published in:

Indian Journal of Natural Products & Resources, 2019, v. 10, n. 2, p. 137

By:

Bergheul, Saida;
Limones-Méndez, Mariana;
Grosjean, Jérémy;
Hehn, Alain;
Olry, Alexandre;
Berkani, Abdellah

Publication type:

Article

CYP98A22, a phenolic ester 3′-hydroxylase specialized in the synthesis of chlorogenic acid, as a new tool for enhancing the furanocoumarin concentration in Ruta graveolens.

Published in:

BMC Plant Biology, 2012, v. 12, n. 1, p. 152, doi. 10.1186/1471-2229-12-152

By:

Karamat, Fazeelat;
Olry, Alexandre;
Doerper, S‚bastien;
Vialart, Guilhem;
Ullmann, Pascaline;
Werck-Reichhart, DaniŠle;
Bourgaud, Fr‚d‚ric;
Hehn, Alain

Publication type:

Article

Identification and characterisation of CYP75A31, a new flavonoid 3′5′-hydroxylase, isolated from Solanum lycopersicum.

Published in:

BMC Plant Biology, 2010, v. 10, p. 1, doi. 10.1186/1471-2229-10-21

By:

Olsen, Kristine M.;
Hehn, Alain;
Jugdé, Hélène;
Slimestad, Rune;
Larbat, Romain;
Bourgaud, Frédéric;
Lillo, Cathrine

Publication type:

Article

The isolation and mapping of a novel hydroxycinnamoyltransferase in the globe artichoke chlorogenic acid pathway.

Published in:

BMC Plant Biology, 2009, v. 9, p. 1, doi. 10.1186/1471-2229-9-30

By:

Comino, Cinzia;
Hehn, Alain;
Moglia, Andrea;
Menin, Barbara;
Bourgaud, Frédéric;
Lanteri, Sergio;
Portis, Ezio

Publication type:

Article

Conservation and diversity of gene families explored using the CODEHOP strategy in higher plants.

Published in:

BMC Plant Biology, 2002, v. 2, p. 7, doi. 10.1186/1471-2229-2-7

By:

Morant, Marc;
Hehn, Alain;
Werck-Reichhart, Danièle

Publication type:

Article