Works by Heguy, Adriana

Results: 81

Rapid progression to glioblastoma in a subset of IDH-mutated astrocytomas: a genome-wide analysis.

Published in:

Journal of Neuro-Oncology, 2017, v. 133, n. 1, p. 183, doi. 10.1007/s11060-017-2431-y

By:

Richardson, Timothy;
Snuderl, Matija;
Serrano, Jonathan;
Karajannis, Matthias;
Heguy, Adriana;
Oliver, Dwight;
Raisanen, Jack;
Maher, Elizabeth;
Pan, Edward;
Barnett, Samuel;
Cai, Chunyu;
Habib, Amyn;
Bachoo, Robert;
Hatanpaa, Kimmo

Publication type:

Article

Breast Cancer Methylomes Establish an Epigenomic Foundation for Metastasis.

Published in:

Science Translational Medicine, 2011, v. 3, n. 75, p. 1, doi. 10.1126/scitranslmed.3001875

By:

Fang Fang;
Turcan, Sevin;
Rimner, Andreas;
Kaufman, Andrew;
Giri, Dilip;
Morris, Luc G. T.;
Ronglai Shen;
Venkatraman Seshan;
Qianxing Mo;
Adriana Heguy;
Baylin, Stephen B.;
Ahuja, Nita;
Viale, Agnes;
Massague, Joan;
Norton, Larry;
Vahdat, Linda T.;
Moynahan, Mary Ellen;
Chan, Timothy A.

Publication type:

Article

Development of a Versatile, Near Full Genome Amplification and Sequencing Approach for a Broad Variety of HIV-1 Group M Variants.

Published in:

Viruses (1999-4915), 2019, v. 11, n. 4, p. 317, doi. 10.3390/v11040317

By:

Banin, Andrew N.;
Tuen, Michael;
Bimela, Jude S.;
Tongo, Marcel;
Zappile, Paul;
Khodadadi-Jamayran, Alireza;
Nanfack, Aubin J.;
Meli, Josephine;
Wang, Xiaohong;
Mbanya, Dora;
Ngogang, Jeanne;
Heguy, Adriana;
Nyambi, Phillipe N.;
Fokunang, Charles;
Duerr, Ralf

Publication type:

Article

Profiling hippocampal neuronal populations reveals unique gene expression mosaics reflective of connectivity-based degeneration in the Ts65Dn mouse model of Down syndrome and Alzheimer's disease.

Published in:

Frontiers in Molecular Neuroscience, 2025, p. 1, doi. 10.3389/fnmol.2025.1546375

By:

Alldred, Melissa J.;
Ibrahim, Kyrillos W.;
Pidikiti, Harshitha;
Lee, Sang Han;
Heguy, Adriana;
Chiosis, Gabriela;
Mufson, Elliott J.;
Stutzmann, Grace E.;
Ginsberg, Stephen D.

Publication type:

Article

Basal forebrain cholinergic neurons are vulnerable in a mouse model of Down syndrome and their molecular fingerprint is rescued by maternal choline supplementation.

Published in:

FASEB Journal, 2023, v. 37, n. 6, p. 1, doi. 10.1096/fj.202202111RR

By:

Alldred, Melissa J.;
Pidikiti, Harshitha;
Heguy, Adriana;
Roussos, Panos;
Ginsberg, Stephen D.

Publication type:

Article

Global DNA Methylation Profiles in Peripheral Blood of WTC-Exposed Community Members with Breast Cancer.

Published in:

International Journal of Environmental Research & Public Health, 2022, v. 19, n. 9, p. 5104, doi. 10.3390/ijerph19095104

By:

Tuminello, Stephanie;
Zhang, Yian;
Yang, Lei;
Durmus, Nedim;
Snuderl, Matija;
Heguy, Adriana;
Zeleniuch-Jacquotte, Anne;
Chen, Yu;
Shao, Yongzhao;
Reibman, Joan;
Arslan, Alan A.

Publication type:

Article

Genome-Wide DNA Methylation Profiles in Community Members Exposed to the World Trade Center Disaster.

Published in:

International Journal of Environmental Research & Public Health, 2020, v. 17, n. 15, p. 5493, doi. 10.3390/ijerph17155493

By:

Arslan, Alan A.;
Tuminello, Stephanie;
Yang, Lei;
Zhang, Yian;
Durmus, Nedim;
Snuderl, Matija;
Heguy, Adriana;
Zeleniuch-Jacquotte, Anne;
Shao, Yongzhao;
Reibman, Joan

Publication type:

Article

De novo assembly and annotation of the singing mouse genome.

Published in:

BMC Genomics, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s12864-023-09678-7

By:

Smith, Samantha K.;
Frazel, Paul W.;
Khodadadi-Jamayran, Alireza;
Zappile, Paul;
Marier, Christian;
Okhovat, Mariam;
Brown, Stuart;
Long, Michael A.;
Heguy, Adriana;
Phelps, Steven M.

Publication type:

Article

Genome-Based Risk Prediction for Early Stage Breast Cancer.

Published in:

Oncologist, 2014, v. 19, n. 10, p. 1019, doi. 10.1634/theoncologist.2014-0124

By:

Adaniel, Christina;
Jhaveri, Komal;
Heguy, Adriana;
Esteva, Francisco J.

Publication type:

Article

Author Correction: Atrx inactivation drives disease-defining phenotypes in glioma cells of origin through global epigenomic remodeling.

Published in:

2022

By:

Danussi, Carla;
Bose, Promita;
Parthasarathy, Prasanna T.;
Silberman, Pedro C.;
Van Arnam, John S.;
Vitucci, Mark;
Tang, Oliver Y.;
Heguy, Adriana;
Wang, Yuxiang;
Chan, Timothy A.;
Riggins, Gregory J.;
Sulman, Erik P.;
Lang, Frederick F.;
Creighton, Chad J.;
Deneen, Benjamin;
Miller, C. Ryan;
Picketts, David J.;
Kannan, Kasthuri;
Huse, Jason T.

Publication type:

Correction Notice

Transposon insertion profiling by sequencing (TIPseq) for mapping LINE-1 insertions in the human genome.

Published in:

Mobile DNA, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1186/s13100-019-0148-5

By:

Steranka, Jared P.;
Tang, Zuojian;
Grivainis, Mark;
Huang, Cheng Ran Lisa;
Payer, Lindsay M.;
Rego, Fernanda O. R.;
Miller, Thiago Luiz Araujo;
Galante, Pedro A. F.;
Ramaswami, Sitharam;
Heguy, Adriana;
Fenyö, David;
Boeke, Jef D.;
Burns, Kathleen H.

Publication type:

Article

Reply to Yan.

Published in:

2023

By:

Hogan, John I;
Duerr, Ralf;
Heguy, Adriana

Publication type:

Letter to the Editor

Remdesivir Resistance in Transplant Recipients With Persistent Coronavirus Disease 2019.

Published in:

Clinical Infectious Diseases, 2023, v. 76, n. 2, p. 342, doi. 10.1093/cid/ciac769

By:

Hogan, John I;
Duerr, Ralf;
Dimartino, Dacia;
Marier, Christian;
Hochman, Sarah E;
Mehta, Sapna;
Wang, Guiqing;
Heguy, Adriana

Publication type:

Article

Investigation of Global Gene Expression of Human Blastocysts Diagnosed as Mosaic using Next-generation Sequencing.

Published in:

Reproductive Sciences, 2022, v. 29, n. 5, p. 1597, doi. 10.1007/s43032-022-00899-x

By:

Maxwell, Susan M.;
Lhakhang, Tenzin C.;
Lin, Ziyan;
Kramer, Yael G.;
Zhang, Yutong;
Wang, Fang;
Heguy, Adriana;
Tsirigos, Aristotelis;
Grifo, James A.;
Licciardi, Frederick

Publication type:

Article

Evaluation of Histone 3 Lysine 27 Trimethylation ( H3K27me3) and Enhancer of Zest 2 ( EZH2) in Pediatric Glial and Glioneuronal Tumors Shows Decreased H3K27me3 in H3F3A K27M Mutant Glioblastomas.

Published in:

Brain Pathology, 2013, v. 23, n. 5, p. 558, doi. 10.1111/bpa.12042

By:

Venneti, Sriram;
Garimella, Mihir T.;
Sullivan, Lisa M.;
Martinez, Daniel;
Huse, Jason T.;
Heguy, Adriana;
Santi, Mariarita;
Thompson, Craig B.;
Judkins, Alexander R.

Publication type:

Article

Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis.

Published in:

Nature Genetics, 2012, v. 44, n. 11, p. 1179, doi. 10.1038/ng.2413

By:

Busque, Lambert;
Patel, Jay P;
Figueroa, Maria E;
Vasanthakumar, Aparna;
Provost, Sylvie;
Hamilou, Zineb;
Mollica, Luigina;
Li, Juan;
Viale, Agnes;
Heguy, Adriana;
Hassimi, Maryam;
Socci, Nicholas;
Bhatt, Parva K;
Gonen, Mithat;
Mason, Christopher E;
Melnick, Ari;
Godley, Lucy A;
Brennan, Cameron W;
Abdel-Wahab, Omar;
Levine, Ross L

Publication type:

Article

Somatic mutations of the Parkinson's disease–associated gene PARK2 in glioblastoma and other human malignancies.

Published in:

Nature Genetics, 2010, v. 42, n. 1, p. 77, doi. 10.1038/ng.491

By:

Veeriah, Selvaraju;
Taylor, Barry S.;
Meng, Shasha;
Fang Fang;
Yilmaz, Emrullah;
Vivanco, Igor;
Janakiraman, Manickam;
Schultz, Nikolaus;
Hanrahan, Aphrothiti J.;
Pao, William;
Ladanyi, Marc;
Sander, Chris;
Heguy, Adriana;
Holland, Eric C.;
Paty, Philip B.;
Mischel, Paul S.;
Liau, Linda;
Cloughesy, Timothy F.;
Mellinghoff, Ingo K.;
Solit, David B.

Publication type:

Article

A germline JAK2 SNP is associated with predisposition to the development of JAK2<sup>V617F</sup>-positive myeloproliferative neoplasms.

Published in:

Nature Genetics, 2009, v. 41, n. 4, p. 455, doi. 10.1038/ng.342

By:

Kilpivaara, Outi;
Mukherjee, Semanti;
Schram, Alison M.;
Wadleigh, Martha;
Mullally, Ann;
Ebert, Benjamin L.;
Bass, Adam;
Marubayashi, Sachie;
Heguy, Adriana;
Garcia-Manero, Guillermo;
Kantarjian, Hagop;
Offit, Kenneth;
Stone, Richard M.;
Gilliland, D Gary;
Klein, Robert J.;
Levine, Ross L.

Publication type:

Article

Variability of Antioxidant-Related Gene Expression in the Airway Epithelium of Cigarette Smokers.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2003, v. 29, n. 3, p. 331, doi. 10.1165/rcmb.2002-0321OC

By:

Hackett, Neil R.;
Heguy, Adriana;
Harvey, Ben-Gary;
O'Connor, Timothy P.;
Luettich, Karsta;
Flieder, Douglas B.;
Kaplan, Rana;
Crystal, Ronald G.

Publication type:

Article

Evidence for Environmental-Human Microbiota Transfer at a Manufacturing Facility with Novel Work-related Respiratory Disease.

Published in:

2020

By:

Wu, Benjamin G.;
Kapoor, Bianca;
Cummings, Kristin J.;
Stanton, Marcia L.;
Nett, Randall J.;
Kreiss, Kathleen;
Abraham, Jerrold L.;
Colby, Thomas V.;
Franko, Angela D.;
Green, Francis H. Y.;
Sanyal, Soma;
Clemente, Jose C.;
Gao, Zhan;
Coffre, Maryaline;
Meyn, Peter;
Heguy, Adriana;
Li, Yonghua;
Sulaiman, Imran;
Borbet, Timothy C.;
Koralov, Sergei B.

Publication type:

journal article

Airway Microbiota Is Associated with Upregulation of the PI3K Pathway in Lung Cancer.

Published in:

2018

By:

Tsay, Jun-Chieh J;
Wu, Benjamin G;
Badri, Michelle H;
Clemente, Jose C;
Shen, Nan;
Meyn, Peter;
Li, Yonghua;
Yie, Ting-An;
Lhakhang, Tenzin;
Olsen, Evan;
Murthy, Vivek;
Michaud, Gaetane;
Sulaiman, Imran;
Tsirigos, Aristotelis;
Heguy, Adriana;
Pass, Harvey;
Weiden, Michael D;
Rom, William N;
Sterman, Daniel H;
Bonneau, Richard

Publication type:

journal article

Identification of kinase fusion oncogenes in post-Chernobyl radiation-induced thyroid cancers.

Published in:

Journal of Clinical Investigation, 2013, v. 123, n. 11, p. 4935, doi. 10.1172/JCI69766

By:

Ricarte-Filho, Julio C.;
Sheng Li;
Garcia-Rendueles, Maria E. R.;
Montero-Conde, Cristina;
Voza, Francesca;
Knauf, Jeffrey A.;
Heguy, Adriana;
Viale, Agnes;
Bogdanova, Tetyana;
Thomas, Geraldine A.;
Mason, Christopher E.;
Fagin, James A.

Publication type:

Article

A Dramatic Difference in Global Gene Expression between TCDD-Treated Atlantic Tomcod Larvae from the Resistant Hudson River and a Nearby Sensitive Population.

Published in:

Genome Biology & Evolution, 2017, v. 9, n. 9, p. 2251, doi. 10.1093/gbe/evx159

By:

Brown, Stuart M.;
Heguy, Adriana;
Zappile, Paul;
Hao Chen;
Goradia, Aayush;
Yilan Wang;
Yuhan Hao;
Roy, Nirmal K.;
Vitale, Kristy;
Chambers, R. Christopher;
Wirgin, Isaac

Publication type:

Article

Distinct Transcriptomic Profiles in the Dorsal Hippocampus and Prelimbic Cortex Are Transiently Regulated following Episodic Learning.

Published in:

Journal of Neuroscience, 2021, v. 41, n. 12, p. 2601, doi. 10.1523/JNEUROSCI.1557-20.2021

By:

Katzman, Aaron;
Khodadadi-Jamayran, Alireza;
Kapeller-Libermann, Dana;
Xiaojing Ye;
Tsirigos, Aristotelis;
Heguy, Adriana;
Alberini, Cristina M.

Publication type:

Article

The integrated landscape of driver genomic alterations in glioblastoma.

Published in:

Nature Genetics, 2013, v. 45, n. 10, p. 1141, doi. 10.1038/ng.2734

By:

Frattini, Veronique;
Trifonov, Vladimir;
Chan, Joseph Minhow;
Castano, Angelica;
Lia, Marie;
Abate, Francesco;
Keir, Stephen T;
Ji, Alan X;
Zoppoli, Pietro;
Niola, Francesco;
Danussi, Carla;
Dolgalev, Igor;
Porrati, Paola;
Pellegatta, Serena;
Heguy, Adriana;
Gupta, Gaurav;
Pisapia, David J;
Canoll, Peter;
Bruce, Jeffrey N;
McLendon, Roger E

Publication type:

Article

The mutational landscape of adenoid cystic carcinoma.

Published in:

Nature Genetics, 2013, v. 45, n. 7, p. 791, doi. 10.1038/ng.2643

By:

Ho, Allen S;
Kannan, Kasthuri;
Roy, David M;
Morris, Luc G T;
Ganly, Ian;
Katabi, Nora;
Ramaswami, Deepa;
Walsh, Logan A;
Eng, Stephanie;
Huse, Jason T;
Zhang, Jianan;
Dolgalev, Igor;
Huberman, Kety;
Heguy, Adriana;
Viale, Agnes;
Drobnjak, Marija;
Leversha, Margaret A;
Rice, Christine E;
Singh, Bhuvanesh;
Iyer, N Gopalakrishna

Publication type:

Article

Interleukin‐17 Inhibition in Spondyloarthritis Is Associated With Subclinical Gut Microbiome Perturbations and a Distinctive Interleukin‐25–Driven Intestinal Inflammation.

Published in:

Arthritis & Rheumatology, 2020, v. 72, n. 4, p. 645, doi. 10.1002/art.41169

By:

Manasson, Julia;
Wallach, David S.;
Guggino, Giuliana;
Stapylton, Matthew;
Badri, Michelle H.;
Solomon, Gary;
Reddy, Soumya M.;
Coras, Roxana;
Aksenov, Alexander A.;
Jones, Drew R.;
Girija, Parvathy V.;
Neimann, Andrea L.;
Heguy, Adriana;
Segal, Leopoldo N.;
Dorrestein, Pieter C.;
Bonneau, Richard;
Guma, Monica;
Ciccia, Francesco;
Ubeda, Carles;
Clemente, Jose C.

Publication type:

Article

Gut Microbiota Perturbations in Reactive Arthritis and Postinfectious Spondyloarthritis.

Published in:

Arthritis & Rheumatology, 2018, v. 70, n. 2, p. 242, doi. 10.1002/art.40359

By:

Manasson, Julia;
Scher, Jose U.;
Shen, Nan;
Clemente, Jose C.;
Garcia Ferrer, Helga R.;
Iraheta, Isa;
Garcia Kutzbach, Abraham;
Ubeda, Carles;
Heguy, Adriana;
Segal, Leopoldo N.;
Von Feldt, Joan M.;
Ogdie, Alexis;
Espinoza, Luis R.

Publication type:

Article

Apolipoprotein E2 Expression Alters Endosomal Pathways in a Mouse Model With Increased Brain Exosome Levels During Aging.

Published in:

Traffic, 2024, v. 25, n. 5, p. 1, doi. 10.1111/tra.12937

By:

Peng, Katherine Y.;
Liemisa, Braison;
Pasato, Jonathan;
D'Acunzo, Pasquale;
Pawlik, Monika;
Heguy, Adriana;
Penikalapati, Sai C.;
Labuza, Amanda;
Pidikiti, Harshitha;
Alldred, Melissa J.;
Ginsberg, Stephen D.;
Levy, Efrat;
Mathews, Paul M.

Publication type:

Article

Single-cell RNA sequencing reveals the effects of chemotherapy on human pancreatic adenocarcinoma and its tumor microenvironment.

Published in:

Nature Communications, 2023, n. 1, p. 1, doi. 10.1038/s41467-023-36296-4

By:

Werba, Gregor;
Weissinger, Daniel;
Kawaler, Emily A.;
Zhao, Ende;
Kalfakakou, Despoina;
Dhara, Surajit;
Wang, Lidong;
Lim, Heather B.;
Oh, Grace;
Jing, Xiaohong;
Beri, Nina;
Khanna, Lauren;
Gonda, Tamas;
Oberstein, Paul;
Hajdu, Cristina;
Loomis, Cynthia;
Heguy, Adriana;
Sherman, Mara H.;
Lund, Amanda W.;
Welling, Theodore H.

Publication type:

Article

Generation of quality-controlled SARS-CoV-2 variant stocks.

Published in:

Nature Protocols, 2023, v. 18, n. 12, p. 3821, doi. 10.1038/s41596-023-00897-6

By:

de Vries, Maren;
Ciabattoni, Grace O.;
Rodriguez-Rodriguez, Bruno A.;
Crosse, Keaton M.;
Papandrea, Dominick;
Samanovic, Marie I.;
Dimartino, Dacia;
Marier, Christian;
Mulligan, Mark J.;
Heguy, Adriana;
Desvignes, Ludovic;
Duerr, Ralf;
Dittmann, Meike

Publication type:

Article

Apolipoprotein L1 risk variants associate with prevalent atherosclerotic disease in African American systemic lupus erythematosus patients.

Published in:

PLoS ONE, 2017, v. 12, n. 8, p. 1, doi. 10.1371/journal.pone.0182483

By:

Blazer, Ashira;
Wang, Binhuan;
Simpson, Danny;
Kirchhoff, Tomas;
Heffron, Sean;
Clancy, Robert M.;
Heguy, Adriana;
Ray, Karina;
Snuderl, Matija;
Buyon, Jill P.

Publication type:

Article

Down-regulation of the notch pathway in human airway epithelium in association with smoking and chronic obstructive pulmonary disease.

Published in:

2009

By:

Tilley AE;
Harvey BG;
Heguy A;
Hackett NR;
Wang R;
O'Connor TP;
Crystal RG;
Tilley, Ann E;
Harvey, Ben-Gary;
Heguy, Adriana;
Hackett, Neil R;
Wang, Rui;
O'Connor, Timothy P;
Crystal, Ronald G

Publication type:

journal article

PIK3CA mutations rarely demonstrate genotypic intratumoral heterogeneity and are selected for in breast cancer progression.

Published in:

2011

By:

Kalinsky, Kevin;
Heguy, Adriana;
Bhanot, Umeshkumar;
Patil, Sujata;
Moynahan, Mary

Publication type:

Report

Cardiac arrhythmia and neuroexcitability gene variants in resected brain tissue from patients with sudden unexpected death in epilepsy (SUDEP).

Published in:

NPJ Genomic Medicine, 2018, v. 3, n. 1, p. N.PAG, doi. 10.1038/s41525-018-0048-5

By:

Friedman, Daniel;
Kannan, Kasthuri;
Faustin, Arline;
Shroff, Seema;
Thomas, Cheddhi;
Heguy, Adriana;
Serrano, Jonathan;
Snuderl, Matija;
Devinsky, Orrin

Publication type:

Article

Author Correction: Single-cell RNA sequencing reveals the effects of chemotherapy on human pancreatic adenocarcinoma and its tumor microenvironment.

Published in:

2023

By:

Werba, Gregor;
Weissinger, Daniel;
Kawaler, Emily A.;
Zhao, Ende;
Kalfakakou, Despoina;
Dhara, Surajit;
Wang, Lidong;
Lim, Heather B.;
Oh, Grace;
Jing, Xiaohong;
Beri, Nina;
Khanna, Lauren;
Gonda, Tamas;
Oberstein, Paul;
Hajdu, Cristina;
Loomis, Cynthia;
Heguy, Adriana;
Sherman, Mara H.;
Lund, Amanda W.;
Welling, Theodore H.

Publication type:

Correction Notice

Association of Age at Diagnosis and Genetic Mutations in Patients With Neuroblastoma.

Published in:

JAMA: Journal of the American Medical Association, 2012, v. 307, n. 10, p. 1062, doi. 10.1001/jama.2012.228

By:

Cheung, Nai-Kong V.;
Jinghui Zhang;
Lu, Charles;
Parker, Matthew;
Bahrami, Armita;
Tickoo, Satish K.;
Heguy, Adriana;
Pappo, Alberto S.;
Federico, Sara;
Dalton, James;
Cheung, Irene Y.;
Li Ding;
Fulton, Bobert;
Jianmin Wang;
Xiang Chen;
Becksfort, Jared;
Jianrong Wu;
Billups, Catherine A.;
Ellison, David;
Mardis, Elaine R.

Publication type:

Article

The protein tyrosine phosphatase receptor D, a broadly inactivated tumor suppressor regulating STAT function.

Published in:

Cell Cycle, 2009, v. 8, n. 19, p. 3063, doi. 10.4161/cc.8.19.9455

By:

Chan, Timothy A.;
Heguy, Adriana

Publication type:

Article

Modification of gene expression of the small airway epithelium in response to cigarette smoking.

Published in:

Journal of Molecular Medicine, 2007, v. 85, n. 1, p. 39, doi. 10.1007/s00109-006-0103-z

By:

Harvey, Ben-Gary;
Heguy, Adriana;
Leopold, Philip L.;
Carolan, Brendan J.;
Ferris, Barbara;
Crystal, Ronald G.

Publication type:

Article

Gene expression profiling of human alveolar macrophages of phenotypically normal smokers and nonsmokers reveals a previously unrecognized subset of genes modulated by cigarette smoking.

Published in:

Journal of Molecular Medicine, 2006, v. 84, n. 4, p. 318, doi. 10.1007/s00109-005-0008-2

By:

Heguy, Adriana;
O'Connor, Timothy P.;
Luettich, Karsta;
Worgall, Stefan;
Cieciuch, Adam;
Harvey, Ben-Gary;
Hackett, Neil R.;
Crystal, Ronald G.

Publication type:

Article

779. Genetic Delivery of an Anti-RSV Antibody Protects Against Pulmonary Infection with RSV in Mice.

Published in:

Molecular Therapy, 2006, v. 13, p. S301, doi. 10.1016/j.ymthe.2006.08.866

By:

Traube, Chani;
Heguy, Adriana;
De, Bishnu;
Krause, Anja;
Wilson, James M.;
Crystal, Ronald G.;
Worgall, Stefan

Publication type:

Article

High Levels of Persistent Expression of α1-Antitrypsin Mediated by the Nonhuman Primate Serotype rh.10 Adeno-associated Virus Despite Preexisting Immunity to Common Human Adeno-associated Viruses.

Published in:

Molecular Therapy, 2006, v. 13, n. 1, p. 67, doi. 10.1016/j.ymthe.2005.09.003

By:

De, Bishnu P.;
Heguy, Adriana;
Hackett, Neil R.;
Ferris, Barbara;
Leopold, Philip L.;
Lee, John;
Pierre, Lorraine;
Gao, Guangping;
Wilson, James M.;
Crystal, Ronald G.

Publication type:

Article

814. Adenovirus-Mediated Gene Transfer Demonstrates That Pirin, a Transcription Factor Up-Regulated in the Bronchial Epithelium by Cigarette Smoke, Mediates Bronchial Epithelial Cell Apoptosis

Published in:

2005

By:

Gelbman, Brian D.;
Heguy, Adriana;
O'Connor, Timothy P.;
Zabner, Joseph;
Crystal, Ronald G.

Publication type:

Abstract

812. Non-Human Primate Serotype rh.10 AAV Directed Therapeutic Serum Levels of α1-antitrypsin Following Intrapleural Administration in Mice with Pre-Existing Immunity to AAV

Published in:

2005

By:

De, Bishnu P.;
Heguy, Adriana;
Hackett, Neil R.;
Lee, John;
Gao, Guangping;
Wilson, James M.;
Crystal, Ronald G.

Publication type:

Abstract

508. Impact of Sex on Serum α1-Antitrypsin Levels Following Intrapleural and Intravenous Administration of AAVrh.10 Vectors to Mice

Published in:

2005

By:

De, Bishnu P.;
Heguy, Adriana;
Hackett, Neil R.;
Gao, Guangping;
Wilson, James M.;
Crystal, Ronald G.

Publication type:

Abstract

367. Safety and Immunological Responses Following Intrapleural Administration of an AAV5 Vector Encoding Human α1-Antitrypsin to Non-Human Primates

Published in:

2005

By:

Harvey, Ben-Gary;
De, Bishnu P.;
Ayala, John P.;
Hackett, Neil R.;
Heguy, Adriana;
Crystal, Ronald

Publication type:

Abstract

Intrapleural administration of a serotype 5 adeno-associated virus coding for α1-antitrypsin mediates persistent, high lung and serum levels of α1-antitrypsin

Published in:

Molecular Therapy, 2004, v. 10, n. 6, p. 1003, doi. 10.1016/j.ymthe.2004.08.022

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De, Bishnu;
Heguy, Adriana;
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Hackett, Neil R.;
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Article

Human blastocysts of normal and abnormal karyotypes display distinct transcriptome profiles.

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Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-33279-0

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Licciardi, Frederick;
Lhakhang, Tenzin;
Kramer, Yael G.;
Zhang, Yutong;
Heguy, Adriana;
Tsirigos, Aristotelis

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Article

Plakophilin-2 is required for transcription of genes that control calcium cycling and cardiac rhythm.

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Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-00127-0

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Cerrone, Marina;
Montnach, Jerome;
Xianming Lin;
Yan-Ting Zhao;
Mingliang Zhang;
Agullo-Pascual, Esperanza;
Leo-Macias, Alejandra;
Alvarado, Francisco J.;
Dolgalev, Igor;
Karathanos, Thomas V.;
Malkani, Kabir;
Van Opbergen, Chantal J. M.;
van Bavel, Joanne J. A.;
Hua-Qian Yang;
Vasquez, Carolina;
Tester, David;
Fowler, Steven;
Fengxia Liang;
Rothenberg, Eli;
Heguy, Adriana

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Article

Apolipoprotein E4 Effects a Distinct Transcriptomic Profile and Dendritic Arbor Characteristics in Hippocampal Neurons Cultured in vitro.

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Frontiers in Aging Neuroscience, 2022, v. 14, p. 1, doi. 10.3389/fnagi.2022.845291

By:

Diaz, Jenny R.;
Martá-Ariza, Mitchell;
Khodadadi-Jamayran, Alireza;
Heguy, Adriana;
Tsirigos, Aristotelis;
Pankiewicz, Joanna E.;
Sullivan, Patrick M.;
Sadowski, Martin J.

Publication type:

Article