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Levels of 4-aminobiphenyl-induced somatic H-ras mutation in mouse liver DNA correlate with potential for liver tumor developmentThis article is a US Government work and, as such, is in the public domain in the United States of America.
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- Molecular Carcinogenesis, 2005, v. 42, n. 4, p. 193, doi. 10.1002/mc.20083
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Evaluating the mutagenicity of N-nitrosodimethylamine in 2D and 3D HepaRG cell cultures using error-corrected next generation sequencing.
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- Archives of Toxicology, 2024, v. 98, n. 6, p. 1919, doi. 10.1007/s00204-024-03731-4
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Genotoxicity assessment of eight nitrosamines using 2D and 3D HepaRG cell models.
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- Archives of Toxicology, 2023, v. 97, n. 10, p. 2785, doi. 10.1007/s00204-023-03560-x
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Genotoxicity evaluation of nitrosamine impurities using human TK6 cells transduced with cytochrome P450s.
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- Archives of Toxicology, 2022, v. 96, n. 11, p. 3077, doi. 10.1007/s00204-022-03347-6
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Manifestation and persistence of Pig-a mutant red blood cells in C57BL/6 mice following single and split doses of N-ethyl- N-nitrosourea.
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- Environmental & Molecular Mutagenesis, 2011, v. 52, n. 9, p. 766, doi. 10.1002/em.20682
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Report on stage III Pig-a mutation assays using benzo[ a]pyrene.
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- Environmental & Molecular Mutagenesis, 2011, v. 52, n. 9, p. 731, doi. 10.1002/em.20675
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Report on stage III Pig-a mutation assays using N-ethyl- N-nitrosourea - comparison with other in vivo genotoxicity endpoints.
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- Environmental & Molecular Mutagenesis, 2011, v. 52, n. 9, p. 721, doi. 10.1002/em.20686
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Monitoring humans for somatic mutation in the endogenous pig-a gene using red blood cells.
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- Environmental & Molecular Mutagenesis, 2011, v. 52, n. 9, p. 784, doi. 10.1002/em.20667
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In vivo assessment of Pig-a gene mutation-recent developments and assay validation.
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- Environmental & Molecular Mutagenesis, 2011, v. 52, n. 9, p. 681, doi. 10.1002/em.20685
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Further development of the rat Pig-a mutation assay: Measuring rat Pig-a mutant bone marrow erythroids and a high throughput assay for mutant peripheral blood reticulocytes.
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- Environmental & Molecular Mutagenesis, 2011, v. 52, n. 9, p. 774, doi. 10.1002/em.20677
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Analysis of mutations in the Pig-a gene of spleen T-cells from N-ethyl- N-nitrosourea-treated fisher 344 rats.
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- Environmental & Molecular Mutagenesis, 2011, v. 52, n. 5, p. 419, doi. 10.1002/em.20654
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The In Vivo Pig-a Gene Mutation Assay, A Potential Tool For Regulatory Safety Assessment.
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- Environmental & Molecular Mutagenesis, 2010, v. 51, n. 8/9, p. 825, doi. 10.1002/em.20627
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Differential Mutagenicity of Aflatoxin B<sub>1</sub> in the Liver of Neonatal and Adult Mice.
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- Environmental & Molecular Mutagenesis, 2010, v. 51, n. 2, p. 156, doi. 10.1002/em.20518
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Flow Cytometric Detection of Pig. A Mutant Red Blood Cells Using an Erythroid-Specific Antibody: Application of the Method for Evaluating the In Vivo Genotoxicity of Methylphenidate in Adolescent Rats.
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- Environmental & Molecular Mutagenesis, 2010, v. 51, n. 2, p. 138, doi. 10.1002/em.20519
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Development of an In Vivo Gene Mutation Assay Using the Endogenous Pig-A Gene: II. Selection of Pig-A Mutant Rat Spleen 1-Cells With Proaerolysin and Sequencing Pig-A cDNA From the Mutants.
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- Environmental & Molecular Mutagenesis, 2008, v. 49, n. 8, p. 622, doi. 10.1002/em.20413
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Effect of Chronic Azathioprine Treatment on Germ-Line Transmission of Hprt Mutation in Mice.
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- Environmental & Molecular Mutagenesis, 2007, v. 48, n. 9, p. 744, doi. 10.1002/em.20352
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Frequency of Hprt mutant lymphocytes and micronucleated erythrocytes in p53‐haplodeficient mice treated perinatally with AZT and AZT in combination with 3TCThis article is a US Government work and, as such, is in the public domain in the United States of America.Invited article on the genotoxicity of perinatal NRTI therapy.
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- Environmental & Molecular Mutagenesis, 2007, v. 48, n. 3/4, p. 270, doi. 10.1002/em.20280
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Transplacental drug transfer and frequency of Tk and Hprt lymphocyte mutants and peripheral blood micronuclei in mice treated transplacentally with zidovudine and lamivudineInvited article on the genotoxicity of perinatal NRTI therapy.The views expressed in this article do not necessarily reflect those of the Food and Drug Administration.This article is a US Government work and, as such, is in the public domain in the United States of America.
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- Environmental & Molecular Mutagenesis, 2007, v. 48, n. 3/4, p. 258, doi. 10.1002/em.20237
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Special section: The 25th anniversary of Environmental and Molecular Mutagenesis.
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- Environmental & Molecular Mutagenesis, 2004, v. 44, n. 5, p. 351
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The Journal celebrates an anniversary.
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- Environmental & Molecular Mutagenesis, 2004, v. 43, n. 1, p. 1
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Editorial.
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- Environmental & Molecular Mutagenesis, 2002, v. 39, n. 4, p. 281, doi. 10.1002/em.10081
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Mutagenicity of γ-radiation, mitomycin C, and etoposide in the Hprt and Tk genes of Tk<sup> +/−</sup> mice†.
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- Environmental & Molecular Mutagenesis, 2002, v. 39, n. 4, p. 342, doi. 10.1002/em.10074
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Editorial.
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- Environmental & Molecular Mutagenesis, 2002, v. 39, n. 1, p. 1, doi. 10.1002/em.10044
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Comparison of hprt and lacI mutant frequency with DNA adduct formation in N-hydroxy-2-acetylaminofluorene-treated Big Blue® rats†.
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- Environmental & Molecular Mutagenesis, 2001, v. 37, n. 3, p. 195, doi. 10.1002/em.1028
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Gene- and tissue-specificity of mutation in Big Blue® rats treated with the hepatocarcinogen N-hydroxy-2-acetylaminofluorene†.
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- Environmental & Molecular Mutagenesis, 2001, v. 37, n. 3, p. 203, doi. 10.1002/em.1029
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7,12-dimethylbenz[ a]anthracene-induced mutation in the Tk gene of Tk<sup> +/−</sup> mice: Automated scoring of lymphocyte clones using a fluorescent viability indicator.
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- Environmental & Molecular Mutagenesis, 2000, v. 36, n. 4, p. 283, doi. 10.1002/1098-2280(2000)36:4<283::AID-EM4>3.0.CO;2-8
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Molecular analysis of in vivo mutations induced by N-ethyl- N-nitrosourea in the autosomal Tk and the X-linked Hprt genes of mouse lymphocytes.
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- Environmental & Molecular Mutagenesis, 1999, v. 34, n. 1, p. 30, doi. 10.1002/(SICI)1098-2280(1999)34:1<30::AID-EM5>3.0.CO;2-R
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Sensitivity of the ΦX174 am3 allele in relation to the endogenous Hprt gene for detecting mutation in transgenic mice.
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- Environmental & Molecular Mutagenesis, 1998, v. 32, n. 3, p. 229, doi. 10.1002/(SICI)1098-2280(1998)32:3<229::AID-EM5>3.0.CO;2-0
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Detection of basepair substitution mutation at a frequency of 1 × 10<sup>−7</sup> by combining two genotypic selection methods, MutEx enrichment and allele-specific competitive blocker PCR.
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- Environmental & Molecular Mutagenesis, 1998, v. 32, n. 3, p. 200, doi. 10.1002/(SICI)1098-2280(1998)32:3<200::AID-EM2>3.0.CO;2-O
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Mutational response at the splenic T-Lymphocyte hprt locus in mice treated as neonates: Contrasting effects of the carcinogens N-ethyl- N-nitrosourea, dimethylnitrosamine, and 2-amino-1-methyl-6-phenylimidazo[4,5- b]pyridine.
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- Environmental & Molecular Mutagenesis, 1998, v. 31, n. 3, p. 243, doi. 10.1002/(SICI)1098-2280(1998)31:3<243::AID-EM5>3.0.CO;2-L
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Comparison of the types of mutations induced by 7,12-dimethylbenz[ a]anthracene in the lacI and hprt genes of Big Blue® rats.
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- Environmental & Molecular Mutagenesis, 1998, v. 31, n. 2, p. 149, doi. 10.1002/(SICI)1098-2280(1998)31:2<149::AID-EM6>3.0.CO;2-H
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Molecular characterization of hprt mutations from chinese hamster ovary cells treated with 1-, 3-, and 6-Nitrosobenz[ a]pyrene.
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- Environmental & Molecular Mutagenesis, 1998, v. 31, n. 1, p. 60, doi. 10.1002/(SICI)1098-2280(1998)31:1<60::AID-EM9>3.0.CO;2-F
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Expansion of rat 6-thioguanine-resistant T-lymphocyte clones by stimulation with ionomycin and a phorbol ester.
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- Environmental & Molecular Mutagenesis, 1998, v. 31, n. 1, p. 97, doi. 10.1002/(SICI)1098-2280(1998)31:1<97::AID-EM13>3.0.CO;2-K
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Other transgenic mutation assays: Development of a novel mouse tk<sup>+/−</sup> embryonic stem cell line for use in mutagenicity studies.
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- Environmental & Molecular Mutagenesis, 1996, v. 28, n. 4, p. 483, doi. 10.1002/(SICI)1098-2280(1996)28:4<483::AID-EM26>3.0.CO;2-A
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DNA sequence analysis of hprt mutations in lymphocytes from Sprague-Dawley rats treated with 7,12-dimethylbenz[a]anthracene.
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- Environmental & Molecular Mutagenesis, 1996, v. 28, n. 1, p. 5, doi. 10.1002/(SICI)1098-2280(1996)28:1<5::AID-EM3>3.0.CO;2-G
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Molecular characterization of mutation and comparison of mutation profiles in the hprt gene of Chinese hamster ovary cells treated with benzo[ a]pyrene trans-7,8-diol- anti-9,10-epoxide, 1-nitrobenzo[ a]pyrene trans-7,8-diol- anti-9,10-epoxide, and 3-nitrobenzo[ a]pyrene trans-7,8-diol- anti-9,10-epoxide
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- Environmental & Molecular Mutagenesis, 1996, v. 27, n. 1, p. 19, doi. 10.1002/(SICI)1098-2280(1996)27:1<19::AID-EM3>3.0.CO;2-9
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Analysis of in vivo mutation induced by N-ethyl- N-nitrosourea in the hprt gene of rat lymphocytes.
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- Environmental & Molecular Mutagenesis, 1995, v. 26, n. 4, p. 261, doi. 10.1002/em.2850260402
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Genomic DNA sequencing of mRNA splicing mutants in the hprt gene of chinese hamster ovary cells.
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- Environmental & Molecular Mutagenesis, 1995, v. 25, n. 2, p. 85, doi. 10.1002/em.2850250202
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Analysis of solvent control and 1-Nitrosopyrene-induced chinese hamster ovary cell mutants by southern and northern blots and the polymerase chain reaction.
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- Environmental & Molecular Mutagenesis, 1992, v. 19, n. 2, p. 147, doi. 10.1002/em.2850190209
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Induction of 6-thioguanine-resistant lymphocytes in fischer 344 rats following in vivo exposure to n-ethyl-n-nitrosourea and cyclophosphamide.
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- Environmental & Molecular Mutagenesis, 1991, v. 17, n. 3, p. 141, doi. 10.1002/em.2850170302
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Nitro group orientation, reduction potential, and direct-acting mutagenicity of nitro-polycyclic aromatic hydrocarbons.
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- Environmental & Molecular Mutagenesis, 1991, v. 17, n. 3, p. 169, doi. 10.1002/em.2850170306
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Role of nitroreduction in the synergistic mutational response induced by mixtures of 1- and 3- nitrobenzo[a]pyrene in Salmonella typhimurium.
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- Environmental & Molecular Mutagenesis, 1989, v. 13, n. 3, p. 203, doi. 10.1002/em.2850130303
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Metabolism of 2-acetylaminofluorene in the chinese hamster ovary cell mutation assay.
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- Environmental & Molecular Mutagenesis, 1988, v. 11, n. 2, p. 167, doi. 10.1002/em.2850110203
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Effect of life stage and target tissue on dose–response assessment of ethyl methane sulfonate‐induced genotoxicity.
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- Environmental & Molecular Mutagenesis, 2021, v. 62, n. 9, p. 482, doi. 10.1002/em.22465
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Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing DNA damage with the CometChip and mutagenesis by Duplex Sequencing.
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- Environmental & Molecular Mutagenesis, 2021, v. 62, n. 5, p. 306, doi. 10.1002/em.22444
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Pig‐a gene mutations in bone marrow granulocytes of procarbazine‐treated F344 rats.
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- Environmental & Molecular Mutagenesis, 2021, v. 62, n. 4, p. 265, doi. 10.1002/em.22430
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Recommendations for conducting the rodent erythrocyte Pig‐a assay: A report from the HESI GTTCPig‐a Workgroup.
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- Environmental & Molecular Mutagenesis, 2021, v. 62, n. 3, p. 227, doi. 10.1002/em.22427
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Celebrating 50 Years of EMGS: A Visionary Idea Continues.
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- Environmental & Molecular Mutagenesis, 2020, v. 61, n. 1, p. 5, doi. 10.1002/em.22350
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Mutation as a Toxicological Endpoint for Regulatory Decision‐Making.
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- Environmental & Molecular Mutagenesis, 2020, v. 61, n. 1, p. 34, doi. 10.1002/em.22338
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Pig‐a gene mutation database.
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- Environmental & Molecular Mutagenesis, 2019, v. 60, n. 8, p. 759, doi. 10.1002/em.22298
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