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The genetic regulation of protein expression in cerebrospinal fluid.
Published in:
EMBO Molecular Medicine, 2023, v. 15, n. 1, p. 1, doi. 10.15252/emmm.202216359
By:
- Hansson, Oskar;
- Kumar, Atul;
- Janelidze, Shorena;
- Stomrud, Erik;
- Insel, Philip S;
- Blennow, Kaj;
- Zetterberg, Henrik;
- Fauman, Eric;
- Hedman, Åsa K;
- Nagle, Michael W;
- Whelan, Christopher D;
- Baird, Denis;
- Mälarstig, Anders;
- Mattsson‐Carlgren, Niklas
Publication type:
Article
Peripheral blood cellular dynamics of rheumatoid arthritis treatment informs about efficacy of response to disease modifying drugs.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-36999-0
By:
- Hedman, Åsa K.;
- Winter, Eitan;
- Yoosuf, Niyaz;
- Benita, Yair;
- Berg, Louise;
- Brynedal, Boel;
- Folkersen, Lasse;
- Klareskog, Lars;
- Maciejewski, Mateusz;
- Sirota-Madi, Alexandra;
- Spector, Yael;
- Ziemek, Daniel;
- Padyukov, Leonid;
- Shen-Orr, Shai S.;
- Jelinsky, Scott A.
Publication type:
Article
Publisher Correction: A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids.
Published in:
2021
By:
- Jhun, Min-A;
- Mendelson, Michael;
- Wilson, Rory;
- Gondalia, Rahul;
- Joehanes, Roby;
- Salfati, Elias;
- Zhao, Xiaoping;
- Braun, Kim Valeska Emilie;
- Do, Anh Nguyet;
- Hedman, Åsa K.;
- Zhang, Tao;
- Carnero-Montoro, Elena;
- Shen, Jincheng;
- Bartz, Traci M.;
- Brody, Jennifer A.;
- Montasser, May E.;
- O'Connell, Jeff R.;
- Yao, Chen;
- Xia, Rui;
- Boerwinkle, Eric
Publication type:
Correction Notice
A multi-ethnic epigenome-wide association study of leukocyte DNA methylation and blood lipids.
Published in:
Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-23899-y
By:
- Jhun, Mina-A;
- Mendelson, Michael;
- Wilson, Rory;
- Gondalia, Rahul;
- Joehanes, Roby;
- Salfati, Elias;
- Zhao, Xiaoping;
- Braun, Kim Valeska Emilie;
- Do, Anh Nguyet;
- Hedman, Åsa K.;
- Zhang, Tao;
- Carnero-Montoro, Elena;
- Shen, Jincheng;
- Bartz, Traci M.;
- Brody, Jennifer A.;
- Montasser, May E.;
- O'Connell, Jeff R.;
- Yao, Chen;
- Xia, Rui;
- Boerwinkle, Eric
Publication type:
Article
Mapping cis- and trans-regulatory effects across multiple tissues in twins.
Published in:
Nature Genetics, 2012, v. 44, n. 10, p. 1084, doi. 10.1038/ng.2394
By:
- Grundberg, Elin;
- Small, Kerrin S;
- Hedman, Åsa K;
- Nica, Alexandra C;
- Buil, Alfonso;
- Keildson, Sarah;
- Bell, Jordana T;
- Yang, Tsun-Po;
- Meduri, Eshwar;
- Barrett, Amy;
- Nisbett, James;
- Sekowska, Magdalena;
- Wilk, Alicja;
- Shin, So-Youn;
- Glass, Daniel;
- Travers, Mary;
- Min, Josine L;
- Ring, Sue;
- Ho, Karen;
- Thorleifsson, Gudmar
Publication type:
Article
Corrigendum: Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes.
Published in:
2011
By:
- Small, Kerrin S;
- Hedman, Åsa K;
- Grundberg, Elin;
- Nica, Alexandra C;
- Thorleifsson, Gudmar;
- Kong, Augustine;
- Thorsteindottir, Unnur;
- Shin, So-Youn;
- Richards, Hannah B;
- Soranzo, Nicole;
- Ahmadi, Kourosh R;
- Lindgren, Cecilia M;
- Stefansson, Kari;
- Dermitzakis, Emmanouil T;
- Deloukas, Panos;
- Spector, Timothy D;
- McCarthy, Mark I
Publication type:
Correction Notice
Identification of an imprinted master trans regulator at the KLF14 locus related to multiple metabolic phenotypes.
Published in:
Nature Genetics, 2011, v. 43, n. 6, p. 561, doi. 10.1038/ng.833
By:
- Small, Kerrin S.;
- Hedman, Åsa K.;
- Grundberg, Elin;
- Nica, Alexandra C.;
- Thorleifsson, Gudmar;
- Kong, Augustine;
- Thorsteindottir, Unnur;
- So-Youn Shin;
- Richards, Hannah B.;
- Soranzo, Nicole;
- Ahmadi, Kourosh R.;
- Lindgren, Cecilia M.;
- Stefansson, Kari;
- Dermitzakis, Emmanouil T.;
- Deloukas, Panos;
- Spector, Timothy D.;
- McCarthy, Mark I.
Publication type:
Article
Evaluation of circulating plasma proteins in breast cancer using Mendelian randomisation.
Published in:
Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-43485-8
By:
- Mälarstig, Anders;
- Grassmann, Felix;
- Dahl, Leo;
- Dimitriou, Marios;
- McLeod, Dianna;
- Gabrielson, Marike;
- Smith-Byrne, Karl;
- Thomas, Cecilia E.;
- Huang, Tzu-Hsuan;
- Forsberg, Simon K. G.;
- Eriksson, Per;
- Ulfstedt, Mikael;
- Johansson, Mattias;
- Sokolov, Aleksandr V.;
- Schiöth, Helgi B.;
- Hall, Per;
- Schwenk, Jochen M.;
- Czene, Kamila;
- Hedman, Åsa K.
Publication type:
Article
The Presence of Methylation Quantitative Trait Loci Indicates a Direct Genetic Influence on the Level of DNA Methylation in Adipose Tissue.
Published in:
PLoS ONE, 2013, v. 8, n. 2, p. 1, doi. 10.1371/journal.pone.0055923
By:
- Drong, Alexander W.;
- Nicholson, George;
- Hedman, Åsa K.;
- Meduri, Eshwar;
- Grundberg, Elin;
- Small, Kerrin S.;
- Shin, So-Youn;
- Bell, Jordana T.;
- Karpe, Fredrik;
- Soranzo, Nicole;
- Spector, Tim D.;
- McCarthy, Mark I.;
- Deloukas, Panos;
- Rantalainen, Mattias;
- Lindgren, Cecilia M.
Publication type:
Article
Dissecting features of epigenetic variants underlying cardiometabolic risk using full-resolution epigenome profiling in regulatory elements.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. 1, doi. 10.1038/s41467-019-09184-z
By:
- Allum, Fiona;
- Hedman, Åsa K.;
- Shao, Xiaojian;
- Cheung, Warren A.;
- Vijay, Jinchu;
- Guénard, Frédéric;
- Kwan, Tony;
- Simon, Marie-Michelle;
- Ge, Bing;
- Moura, Cristiano;
- Boulier, Elodie;
- Rönnblom, Lars;
- Bernatsky, Sasha;
- Lathrop, Mark;
- McCarthy, Mark I.;
- Deloukas, Panos;
- Tchernof, André;
- Pastinen, Tomi;
- Vohl, Marie-Claude;
- Grundberg, Elin
Publication type:
Article
IEA EBC Annex83 Positive Energy Districts.
Published in:
Buildings (2075-5309), 2021, v. 11, n. 3, p. 130, doi. 10.3390/buildings11030130
By:
- Hedman, Åsa;
- Rehman, Hassam Ur;
- Gabaldón, Andrea;
- Bisello, Adriano;
- Albert-Seifried, Vicky;
- Zhang, Xingxing;
- Guarino, Francesco;
- Grynning, Steinar;
- Eicker, Ursula;
- Neumann, Hans-Martin;
- Tuominen, Pekka;
- Reda, Francesco;
- Santamouris, Matheos;
- Dodoo, Ambrose;
- Srinivasan, Ravi;
- Santos, Paulo
Publication type:
Article
SW-ARRAY: a dynamic programming solution for the identification of copy-number changes in genomic DNA using array comparative genome hybridization data.
Published in:
Nucleic Acids Research, 2005, v. 33, n. 11, p. 3455, doi. 10.1093/nar/gki643
By:
- Price, Thomas S.;
- Regan, Regina;
- Mott, Richard;
- Hedman, Åsa;
- Honey, Ben;
- Daniels, Rachael J.;
- Smith, Lee;
- Greenfield, Andy;
- Tiganescu, Ana;
- Buckle, Veronica;
- Ventress, Nicki;
- Ayyub, Helena;
- Salhan, Anita;
- Pedraza-Diaz, Susana;
- Broxholme, John;
- Ragoussis, Jiannis;
- Higgs, Douglas R.;
- Flint, Jonathan;
- Knight, Samantha J. L.
Publication type:
Article
DNA methylation patterns associated with oxidative stress in an ageing population.
Published in:
BMC Medical Genomics, 2016, v. 9, p. 1, doi. 10.1186/s12920-016-0235-0
By:
- Hedman, Åsa K.;
- Zilmer, Mihkel;
- Sundström, Johan;
- Lind, Lars;
- Ingelsson, Erik
Publication type:
Article
Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels.
Published in:
Nature Communications, 2016, v. 7, n. 2, p. 10494, doi. 10.1038/ncomms10494
By:
- Kilpeläinen, Tuomas O.;
- Carli, Jayne F. Martin;
- Skowronski, Alicja A.;
- Sun, Qi;
- Kriebel, Jennifer;
- Feitosa, Mary F;
- Hedman, Åsa K.;
- Drong, Alexander W.;
- Hayes, James E.;
- Zhao, Jinghua;
- Pers, Tune H.;
- Schick, Ursula;
- Grarup, Niels;
- Kutalik, Zoltán;
- Trompet, Stella;
- Mangino, Massimo;
- Kristiansson, Kati;
- Beekman, Marian;
- Lyytikäinen, Leo-Pekka;
- Eriksson, Joel
Publication type:
Article
New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk.
Published in:
Nature Communications, 2016, v. 7, n. 2, p. 10495, doi. 10.1038/ncomms10495
By:
- Lu, Yingchang;
- Day, Felix R.;
- Gustafsson, Stefan;
- Buchkovich, Martin L.;
- Na, Jianbo;
- Bataille, Veronique;
- Cousminer, Diana L.;
- Dastani, Zari;
- Drong, Alexander W.;
- Esko, Tõnu;
- Evans, David M.;
- Falchi, Mario;
- Feitosa, Mary F.;
- Ferreira, Teresa;
- Hedman, Åsa K.;
- Haring, Robin;
- Hysi, Pirro G.;
- Iles, Mark M.;
- Justice, Anne E.;
- Kanoni, Stavroula
Publication type:
Article
Erratum: Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants.
Published in:
Nature Communications, 2015, v. 6, n. 7, p. 8016, doi. 10.1038/ncomms9016
By:
- Allum, Fiona;
- Shao, Xiaojian;
- Guénard, Frédéric;
- Simon, Marie-Michelle;
- Busche, Stephan;
- Caron, Maxime;
- Lambourne, John;
- Lessard, Julie;
- Tandre, Karolina;
- Hedman, Åsa K;
- Kwan, Tony;
- Ge, Bing;
- Rönnblom, Lars;
- McCarthy, Mark I;
- Deloukas, Panos;
- Richmond, Todd;
- Burgess, Daniel;
- Spector, Timothy D;
- Tchernof, André;
- Marceau, Simon
Publication type:
Article
Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants.
Published in:
Nature Communications, 2015, v. 6, n. 5, p. 7211, doi. 10.1038/ncomms8211
By:
- Allum, Fiona;
- Shao, Xiaojian;
- Guénard, Frédéric;
- Simon, Marie-Michelle;
- Busche, Stephan;
- Caron, Maxime;
- Lambourne, John;
- Lessard, Julie;
- Tandre, Karolina;
- Hedman, Åsa K.;
- Kwan, Tony;
- Ge, Bing;
- Rönnblom, Lars;
- McCarthy, Mark I.;
- Deloukas, Panos;
- Richmond, Todd;
- Burgess, Daniel;
- Spector, Timothy D.;
- Tchernof, André;
- Marceau, Simon
Publication type:
Article
Gene expression changes with age in skin, adipose tissue, blood and brain.
Published in:
Genome Biology, 2013, v. 14, n. 7, p. R75, doi. 10.1186/gb-2013-14-7-r75
By:
- Glass, Daniel;
- Viñuela, Ana;
- Davies, Matthew N;
- Ramasamy, Adaikalavan;
- Parts, Leopold;
- Knowles, David;
- Brown, Andrew A;
- Hedman, Åsa K;
- Small, Kerrin S;
- Buil, Alfonso;
- Grundberg, Elin;
- Nica, Alexandra C;
- Nestle, Frank O;
- Ryten, Mina;
- the UK Brain Expression consortium;
- the MuTHER consortium;
- Durbin, Richard;
- McCarthy, Mark I;
- Deloukas, Panagiotis;
- Dermitzakis, Emmanouil T
Publication type:
Article
Tea and coffee consumption in relation to DNA methylation in four European cohorts.
Published in:
Human Molecular Genetics, 2017, v. 26, n. 16, p. 3221, doi. 10.1093/hmg/ddx194
By:
- Ek, Weronica E.;
- Tobi, Elmar W.;
- Ahsan, Muhammad;
- Lampa, Erik;
- Ponzi, Erica;
- Kyrtopoulos, Soterios A.;
- Georgiadis, Panagiotis;
- Lumey, L. H.;
- Heijmans, Bastiaan T.;
- Botsivali, Maria;
- Bergdahl, Ingvar A.;
- Karlsson, Torgny;
- Rask-Andersen, Mathias;
- Palli, Domenico;
- Ingelsson, Erik;
- Hedman, Åsa K.;
- Nilsson, Lena M.;
- Vineis, Paolo;
- Lind, Lars;
- Flanagan, James M.
Publication type:
Article
Genome-wide DNA methylation study identifies genes associated with the cardiovascular biomarker GDF-15.
Published in:
Human Molecular Genetics, 2016, v. 25, n. 4, p. 817, doi. 10.1093/hmg/ddv511
By:
- Ek, Weronica E.;
- Hedman, Åsa K.;
- Enroth, Stefan;
- Morris, Andrew P.;
- Lindgren, Cecilia M.;
- Mahajan, Anubha;
- Gustafsson, Stefan;
- Gyllensten, Ulf;
- Lind, Lars;
- Johansson, Åsa
Publication type:
Article
Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci.
Published in:
Human Molecular Genetics, 2015, v. 24, n. 15, p. 4464, doi. 10.1093/hmg/ddv161
By:
- Demerath, Ellen W.;
- Guan, Weihua;
- Grove, Megan L.;
- Aslibekyan, Stella;
- Mendelson, Michael;
- Yi-Hui Zhou;
- Hedman, Åsa K.;
- Sandling, Johanna K.;
- Li-An Li;
- Irvin, Marguerite R.;
- Degui Zhi;
- Deloukas, Panos;
- Liming Liang;
- Chunyu Liu;
- Bressler, Jan;
- Spector, Tim D.;
- North, Kari;
- Yun Li;
- Absher, Devin M.;
- Levy, Daniel
Publication type:
Article
Genome-wide enrichment analysis between endometriosis and obesity-related traits reveals novel susceptibility loci.
Published in:
Human Molecular Genetics, 2015, v. 24, n. 4, p. 1185, doi. 10.1093/hmg/ddu516
By:
- Rahmioglu, Nilufer;
- Macgregor, Stuart;
- Drong, Alexander W.;
- Hedman, Åsa K.;
- Harris, Holly R.;
- Randall, Joshua C.;
- Prokopenko, Inga;
- Nyholt, Dale R.;
- Morris, Andrew P.;
- Montgomery, Grant W.;
- Missmer, Stacey A.;
- Lindgren, Cecilia M.;
- Zondervan, Krina T.
Publication type:
Article
Comprehensive longitudinal study of epigenetic mutations in aging.
Published in:
Clinical Epigenetics, 2019, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13148-019-0788-9
By:
- Wang, Yunzhang;
- Karlsson, Robert;
- Jylhävä, Juulia;
- Hedman, Åsa K.;
- Almqvist, Catarina;
- Karlsson, Ida K.;
- Pedersen, Nancy L.;
- Almgren, Malin;
- Hägg, Sara
Publication type:
Article
The impact of circulating protein levels identified by affinity proteomics on short-term, overall breast cancer risk.
Published in:
British Journal of Cancer, 2024, v. 130, n. 4, p. 620, doi. 10.1038/s41416-023-02541-2
By:
- Grassmann, Felix;
- Mälarstig, Anders;
- Dahl, Leo;
- Bendes, Annika;
- Dale, Matilda;
- Thomas, Cecilia Engel;
- Gabrielsson, Marike;
- Hedman, Åsa K.;
- Eriksson, Mikael;
- Margolin, Sara;
- Huang, Tzu-Hsuan;
- Ulfstedt, Mikael;
- Forsberg, Simon;
- Eriksson, Per;
- Johansson, Mattias;
- Hall, Per;
- Schwenk, Jochen M.;
- Czene, Kamila
Publication type:
Article
Large-scale Metabolomic Profiling Identifies Novel Biomarkers for Incident Coronary Heart Disease.
Published in:
PLoS Genetics, 2014, v. 10, n. 12, p. 1, doi. 10.1371/journal.pgen.1004801
By:
- Ganna, Andrea;
- Salihovic, Samira;
- Sundström, Johan;
- Broeckling, Corey D.;
- Hedman, Åsa K.;
- Magnusson, Patrik K. E.;
- Pedersen, Nancy L.;
- Larsson, Anders;
- Siegbahn, Agneta;
- Zilmer, Mihkel;
- Prenni, Jessica;
- Ärnlöv, Johan;
- Lind, Lars;
- Fall, Tove;
- Ingelsson, Erik
Publication type:
Article
Extent, Causes, and Consequences of Small RNA Expression Variation in Human Adipose Tissue.
Published in:
PLoS Genetics, 2012, v. 8, n. 5, p. 1, doi. 10.1371/journal.pgen.1002704
By:
- Parts, Leopold;
- Hedman, Åsa K.;
- Keildson, Sarah;
- Knights, Andrew J.;
- Abreu-Goodger, Cei;
- Van De Bunt, Martijn;
- Guerra-Assunção, José Afonso;
- Bartonicek, Nenad;
- van Dongen, Stijn;
- Mägi, Reedik;
- Nisbet, James;
- Barrett, Amy;
- Rantalainen, Mattias;
- Nica, Alexandra C.;
- Quail, Michael A.;
- Small, Kerrin S.;
- Glass, Daniel;
- Enright, Anton J.;
- Winn, John;
- Deloukas, Panos
Publication type:
Article
Association of Body Mass Index with DNA Methylation and Gene Expression in Blood Cells and Relations to Cardiometabolic Disease: A Mendelian Randomization Approach.
Published in:
2017
By:
- Mendelson, Michael M.;
- Marioni, Riccardo E.;
- Joehanes, Roby;
- Liu, Chunyu;
- Hedman, Åsa K.;
- Aslibekyan, Stella;
- Demerath, Ellen W.;
- Guan, Weihua;
- Zhi, Degui;
- Yao, Chen;
- Huan, Tianxiao;
- Willinger, Christine;
- Chen, Brian;
- Courchesne, Paul;
- Multhaup, Michael;
- Irvin, Marguerite R.;
- Cohain, Ariella;
- Schadt, Eric E.;
- Grove, Megan L.;
- Bressler, Jan
Publication type:
journal article
Identifying therapeutic targets for cancer among 2074 circulating proteins and risk of nine cancers.
Published in:
Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46834-3
By:
- Smith-Byrne, Karl;
- Hedman, Åsa;
- Dimitriou, Marios;
- Desai, Trishna;
- Sokolov, Alexandr V.;
- Schioth, Helgi B.;
- Koprulu, Mine;
- Pietzner, Maik;
- Langenberg, Claudia;
- Atkins, Joshua;
- Penha, Ricardo Cortez;
- McKay, James;
- Brennan, Paul;
- Sirui Zhou;
- Richards, Brent J.;
- Yarmolinsky, James;
- Martin, Richard M.;
- Borlido, Joana;
- Mu, Xinmeng J.;
- Butterworth, Adam
Publication type:
Article
Genome-wide association and Mendelian randomisation analysis provide insights into the pathogenesis of heart failure.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-019-13690-5
By:
- Shah, Sonia;
- Henry, Albert;
- Roselli, Carolina;
- Lin, Honghuang;
- Sveinbjörnsson, Garðar;
- Fatemifar, Ghazaleh;
- Hedman, Åsa K.;
- Wilk, Jemma B.;
- Morley, Michael P.;
- Chaffin, Mark D.;
- Helgadottir, Anna;
- Verweij, Niek;
- Dehghan, Abbas;
- Almgren, Peter;
- Andersson, Charlotte;
- Aragam, Krishna G.;
- Ärnlöv, Johan;
- Backman, Joshua D.;
- Biggs, Mary L.;
- Bloom, Heather L.
Publication type:
Article
Expression of Phosphofructokinase in Skeletal Muscle Is Influenced by Genetic Variation and Associated With Insulin Sensitivity.
Published in:
Diabetes, 2014, v. 63, n. 3, p. 1154, doi. 10.2337/db13-1301
By:
- Keildson, Sarah;
- Fadista, Joao;
- Ladenvall, Claes;
- Hedman, Åsa K.;
- Elgzyri, Targ;
- Small, Kerrin S.;
- Grundberg, Elin;
- Nica, Alexandra C.;
- Glass, Daniel;
- Richards, J. Brent;
- Barrett, Amy;
- Nisbet, James;
- Hou-Feng Zheng;
- Rönn, Tina;
- Ström, Kristoffer;
- Eriksson, Karl-Fredrik;
- Prokopenko, Inga;
- Spector, Timothy D.;
- Dermitzakis, Emmanouil T.;
- Deloukas, Panos
Publication type:
Article

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