Works by Heckel, Alexander

Results: 104

Immunoengineering eines Photocage‐geschützten 5′‐Triphosphat‐Oligoribonukleotid‐Liganden zur spatiotemporalen Kontrolle der RIG‐I‐Aktivierung bei Tumoren.

Published in:

Angewandte Chemie, 2025, v. 137, n. 21, p. 1, doi. 10.1002/ange.202423321

By:

Lewash, Sandra Anika;
McKenney, Vivien Rose;
Wuebben, Christine;
Ludwig, Janos;
Hosni, Racha;
Radzey, Dirk;
Toma, Marieta I.;
Bartok, Eva;
Schlee, Martin;
Zillinger, Thomas;
Heckel, Alexander;
Hartmann, Gunther

Publication type:

Article

Immunoengineering of a Photocaged 5´‐triphosphate Oligoribonucleotide Ligand for Spatiotemporal Control of RIG‐I Activation in Cancer.

Published in:

Angewandte Chemie International Edition, 2025, v. 64, n. 21, p. 1, doi. 10.1002/anie.202423321

By:

Lewash, Sandra Anika;
McKenney, Vivien Rose;
Wuebben, Christine;
Ludwig, Janos;
Hosni, Racha;
Radzey, Dirk;
Toma, Marieta I.;
Bartok, Eva;
Schlee, Martin;
Zillinger, Thomas;
Heckel, Alexander;
Hartmann, Gunther

Publication type:

Article

Frosted DNA: β‐Galactosidase Control of Oligonucleotide Activity.

Published in:

Chemistry - A European Journal, 2025, v. 31, n. 24, p. 1, doi. 10.1002/chem.202500347

By:

Sinsel, Fabian;
Külp, Marius;
Rieger, Michael A.;
Heckel, Alexander

Publication type:

Article

A Blue Light and Two‐Photon Activatable Rhodamine Fluorophore.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 38, p. 1, doi. 10.1002/chem.202300997

By:

Weber, Rebekka;
Junek, Stephan;
Heckel, Alexander

Publication type:

Article

Extending the Palette of Green Coumarin Photocages – Oligonucleotide Fragmentation and Superior 5'‐Caps.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 30, p. 1, doi. 10.1002/chem.202300390

By:

Kaufmann, Janik;
Wolf, Jonas;
Heckel, Alexander

Publication type:

Article

Rhodamine‐Sensitized Two‐Photon Activation of a Red Light‐Absorbing BODIPY Photocage.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 25, p. 1, doi. 10.1002/chem.202300149

By:

Weber, Rebekka;
Chok, Kerby;
Junek, Stephan;
Glaubitz, Clemens;
Heckel, Alexander

Publication type:

Article

Chromatic Selectivity of Coumarin‐Caged Oligonucleotides.

Published in:

Chemistry - A European Journal, 2023, v. 29, n. 17, p. 1, doi. 10.1002/chem.202204014

By:

Kaufmann, Janik;
Sinsel, Fabian;
Heckel, Alexander

Publication type:

Article

Green‐Light Activatable BODIPY and Coumarin 5'‐Caps for Oligonucleotide Photocaging.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 36, p. 1, doi. 10.1002/chem.202200477

By:

Kaufmann, Janik;
Müller, Patricia;
Andreadou, Eleni;
Heckel, Alexander

Publication type:

Article

Inactivation of Competitive Decay Channels Leads to Enhanced Coumarin Photochemistry.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 35, p. 1, doi. 10.1002/chem.202200647

By:

Klimek, Robin;
Asido, Marvin;
Hermanns, Volker;
Junek, Stephan;
Wachtveitl, Josef;
Heckel, Alexander

Publication type:

Article

Influence of the Absolute Configuration of NPE-Caged Cytosine on DNA Single Base Pair Stability.

Published in:

Angewandte Chemie, 2014, v. 126, n. 4, p. 1090, doi. 10.1002/ange.201307852

By:

Steinert, Hannah S.;
Schäfer, Florian;
Jonker, Hendrik R. A.;
Heckel, Alexander;
Schwalbe, Harald

Publication type:

Article

Regulation der Angiogenese durch lichtinduzierbare AntimiRs.

Published in:

Angewandte Chemie, 2013, v. 125, n. 51, p. 13801, doi. 10.1002/ange.201307502

By:

Schäfer, Florian;
Wagner, Jasmin;
Knau, Andrea;
Dimmeler, Stefanie;
Heckel, Alexander

Publication type:

Article

Aptamerbasiertes Caging zur selektiven Maskierung von Proteindomänen.

Published in:

Angewandte Chemie, 2013, v. 125, n. 45, p. 12129, doi. 10.1002/ange.201306686

By:

Rohrbach, Falk;
Schäfer, Florian;
Fichte, Manuela A. H.;
Pfeiffer, Franziska;
Müller, Jens;
Pötzsch, Bernd;
Heckel, Alexander;
Mayer, Günter

Publication type:

Article

Innenrücktitelbild: Aptamerbasiertes Caging zur selektiven Maskierung von Proteindomänen (Angew. Chem. 45/2013).

Published in:

Angewandte Chemie, 2013, v. 125, n. 45, p. 12159, doi. 10.1002/ange.201308371

By:

Rohrbach, Falk;
Schäfer, Florian;
Fichte, Manuela A. H.;
Pfeiffer, Franziska;
Müller, Jens;
Pötzsch, Bernd;
Heckel, Alexander;
Mayer, Günter

Publication type:

Article

Lichtgesteuerte Werkzeuge.

Published in:

Angewandte Chemie, 2012, v. 124, n. 34, p. 8572, doi. 10.1002/ange.201202134

By:

Brieke, Clara;
Rohrbach, Falk;
Gottschalk, Alexander;
Mayer, Günter;
Heckel, Alexander

Publication type:

Article

Innentitelbild: Photoaktivierbares Glutathion - lichtgesteuerte Proteinwechselwirkung (Angew. Chem. 16/2012).

Published in:

Angewandte Chemie, 2012, v. 124, n. 16, p. 3788, doi. 10.1002/ange.201201327

By:

Gatterdam, Volker;
Stoess, Tatjana;
Menge, Clara;
Heckel, Alexander;
Tampé, Robert

Publication type:

Article

Photoaktivierbares Glutathion - lichtgesteuerte Proteinwechselwirkung.

Published in:

Angewandte Chemie, 2012, v. 124, n. 16, p. 4027, doi. 10.1002/ange.201108073

By:

Gatterdam, Volker;
Stoess, Tatjana;
Menge, Clara;
Heckel, Alexander;
Tampé, Robert

Publication type:

Article

Ein Antikoagulans mit photoaktivierbarer AntidotaktivitätDiese Arbeit wurde durch Drittmittel des Verbandes der Chemischen Industrie (für A.H. und G.M.) sowie ein Emmy Noether-Stipendium (DFG) für A.H. ermöglicht. Wir danken...

Published in:

Angewandte Chemie, 2006, v. 118, n. 40, p. 6900, doi. 10.1002/ange.200602346

By:

Alexander Heckel;
Maximilian C. R. Buff;
Marie-Sophie L. Raddatz;
Jens Müller;
Bernd Pötzsch;
Günter Mayer

Publication type:

Article

Biologisch aktive Moleküle mit "Lichtschalter".

Published in:

Angewandte Chemie, 2006, v. 118, n. 30, p. 5020, doi. 10.1002/ange.200600387

By:

Günter Mayer;
Alexander Heckel

Publication type:

Article

The ribosome assembly factor Nep1 responsible for Bowen–Conradi syndrome is a pseudouridine-N1-specific methyltransferase.

Published in:

Nucleic Acids Research, 2010, v. 38, n. 7, p. 2387, doi. 10.1093/nar/gkp1189

By:

Wurm, Jan Philip;
Meyer, Britta;
Bahr, Ute;
Held, Martin;
Frolow, Olga;
Kötter, Peter;
Engels, Joachim W.;
Heckel, Alexander;
Karas, Michael;
Entian, Karl-Dieter;
Wöhnert, Jens

Publication type:

Article

Dependence of aptamer activity on opposed terminal extensions: improvement of light-regulation efficiency.

Published in:

Nucleic Acids Research, 2010, v. 38, n. 6, p. 2111, doi. 10.1093/nar/gkp1148

By:

Buff, Maximilian C. R.;
Schäfer, Florian;
Wulffen, Bernhard;
Müller, Jens;
Pötzsch, Bernd;
Heckel, Alexander;
Mayer, Günter

Publication type:

Article

Influence of structural variation on nuclear localization of DNA‐binding polyamide‐fluorophore conjugates.

Published in:

Nucleic Acids Research, 2004, v. 32, n. 9, p. 2802, doi. 10.1093/nar/gkh609

By:

Edelson, Benjamin S.;
Best, Timothy P.;
Olenyuk, Bogdan;
Nickols, Nicholas G.;
Doss, Raymond M.;
Foister, Shane;
Heckel, Alexander;
Dervan, Peter B.

Publication type:

Article

Iminothioindoxyl Donors with Exceptionally High Cross Section for Protein Vibrational Energy Transfer.

Published in:

Angewandte Chemie International Edition, 2024, v. 63, n. 9, p. 1, doi. 10.1002/anie.202317047

By:

Feid, Carolin;
Luma, Larita;
Fischer, Tobias;
Löffler, Jan Gerrit;
Grebenovsky, Nikolai;
Wachtveitl, Josef;
Heckel, Alexander;
Bredenbeck, Jens

Publication type:

Article

Iminothioindoxyl Donors with Exceptionally High Cross Section for Protein Vibrational Energy Transfer.

Published in:

Angewandte Chemie International Edition, 2024, v. 63, n. 9, p. 1, doi. 10.1002/anie.202317047

By:

Feid, Carolin;
Luma, Larita;
Fischer, Tobias;
Löffler, Jan Gerrit;
Grebenovsky, Nikolai;
Wachtveitl, Josef;
Heckel, Alexander;
Bredenbeck, Jens

Publication type:

Article

Solid‐Phase‐Supported Chemoenzymatic Synthesis of a Light‐Activatable tRNA Derivative.

Published in:

Angewandte Chemie International Edition, 2022, v. 61, n. 1, p. 1, doi. 10.1002/anie.202111613

By:

Blümler, Anja;
Schwalbe, Harald;
Heckel, Alexander

Publication type:

Article

Controlling Coagulation in Blood with Red Light.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 41, p. 22441, doi. 10.1002/anie.202108468

By:

Müller, Patricia;
Sahlbach, Marlen;
Gasper, Simone;
Mayer, Günter;
Müller, Jens;
Pötzsch, Bernd;
Heckel, Alexander

Publication type:

Article

Lichtinduzierte Transkription mit vorübergehend fehlgepaarten OligonucleotidenDiese Arbeit wurde durch ein Liebig-Stipendium des Verbandes der Chemischen Industrie für A.H. unterstützt.

Published in:

Angewandte Chemie, 2005, v. 117, n. 3, p. 475, doi. 10.1002/ange.200461779

By:

Lenz Kröck;
Alexander Heckel

Publication type:

Article

Electronic Circular Dichroism Unravels Atropisomers of a Broadly Absorbing Fulgide Derivative.

Published in:

ChemPhotoChem, 2022, v. 6, n. 9, p. 1, doi. 10.1002/cptc.202200057

By:

Hermanns, Volker;
Scheurer, Maximilian;
Dreuw, Andreas;
Wachtveitl, Josef;
Braun, Markus;
Heckel, Alexander

Publication type:

Article

Photoswitchable 2‐Phenyldiazenyl‐Purines and their Influence on DNA Hybridization.

Published in:

ChemPhotoChem, 2020, v. 4, n. 11, p. 5245, doi. 10.1002/cptc.202000162

By:

Grebenovsky, Nikolai;
Hermanns, Volker;
Heckel, Alexander

Publication type:

Article

Coumarin‐4‐ylmethyl‐ and p‐Hydroxyphenacyl‐Based Photoacid Generators with High Solubility in Aqueous Media: Synthesis, Stability and Photolysis.

Published in:

ChemPhotoChem, 2020, v. 4, n. 3, p. 207, doi. 10.1002/cptc.201900258

By:

Adatia, Karishma K.;
Halbritter, Thomas;
Reinfelds, Matiss;
Michele, Andre;
Tran, Michael;
Laschat, Sabine;
Heckel, Alexander;
Tovar, Günter E. M.;
Southan, Alexander

Publication type:

Article

A Robust, Broadly Absorbing Fulgide Derivative as a Universal Chemical Actinometer for the UV to NIR Region.

Published in:

ChemPhotoChem, 2019, v. 3, n. 6, p. 441, doi. 10.1002/cptc.201900010

By:

Reinfelds, Matiss;
Hermanns, Volker;
Halbritter, Thomas;
Wachtveitl, Josef;
Braun, Markus;
Slanina, Tomáš;
Heckel, Alexander

Publication type:

Article

Life times of metastable states guide regulatory signaling in transcriptional riboswitches.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03375-w

By:

Helmling, Christina;
Klötzner, Dean-Paulos;
Sochor, Florian;
Mooney, Rachel Anne;
Wacker, Anna;
Landick, Robert;
Fürtig, Boris;
Heckel, Alexander;
Schwalbe, Harald

Publication type:

Article

Photolabile Protecting Groups for Nitroxide Spin Labels.

Published in:

European Journal of Organic Chemistry, 2014, v. 2014, n. 19, p. 4037, doi. 10.1002/ejoc.201301692

By:

Seven, Ibrahim;
Weinrich, Timo;
Gränz, Markus;
Grünewald, Christian;
Brüß, Silke;
Krstić, Ivan;
Prisner, Thomas F.;
Heckel, Alexander;
Göbel, Michael W.

Publication type:

Article

Prion Protein Amyloid Formation Involves Structural Rearrangements in the C-Terminal Domain.

Published in:

ChemBioChem, 2010, v. 11, n. 9, p. 1208, doi. 10.1002/cbic.201000076

By:

Kumar, Jitendra;
Sreeramulu, Sridhar;
Schmidt, Thorsten L.;
Richter, Christian;
Vonck, Janet;
Heckel, Alexander;
Glaubitz, Clemens;
Schwalbe, Harald

Publication type:

Article

Differential Regulation of Protein Subdomain Activity with Caged Bivalent Ligands.

Published in:

ChemBioChem, 2009, v. 10, n. 4, p. 654, doi. 10.1002/cbic.200800814

By:

Mayer, Günter;
Müller, Jens;
Mack, Timo;
Freitag, Daniel F.;
Höver, Thomas;
Pötzsch, Bernd;
Heckel, Alexander

Publication type:

Article

Light-Stimulated Patterning of Cells.

Published in:

ChemBioChem, 2007, v. 8, n. 8, p. 857, doi. 10.1002/cbic.200700093

By:

Mayer, Günter;
Heckel, Alexander

Publication type:

Article

Cover Picture: Light-Induced Formation of G-Quadruplex DNA Secondary Structures (ChemBioChem 11/2005).

Published in:

ChemBioChem, 2005, v. 6, n. 11, p. 1913, doi. 10.1002/cbic.200590036

By:

Günter Mayer;
Lenz Kröck;
Vera Mikat;
Marianne Engeser;
Alexander Heckel

Publication type:

Article

Light-Induced Formation of G-Quadruplex DNA Secondary Structures.

Published in:

ChemBioChem, 2005, v. 6, n. 11, p. 1966, doi. 10.1002/cbic.200500198

By:

Günter Mayer;
Lenz Kröck;
Vera Mikat;
Marianne Engeser;
Alexander Heckel

Publication type:

Article

A New DNA Analogue with Expanded Size and Scope.

Published in:

ChemBioChem, 2004, v. 5, n. 6, p. 765, doi. 10.1002/cbic.200400001

By:

Alexander Heckel

Publication type:

Article

Chemo‐Enzymatic Synthesis of Position‐Specifically Modified RNA for Biophysical Studies including Light Control and NMR Spectroscopy.

Published in:

Angewandte Chemie International Edition, 2018, v. 57, n. 37, p. 12017, doi. 10.1002/anie.201807125

By:

Keyhani, Sara;
Goldau, Thomas;
Blümler, Anja;
Heckel, Alexander;
Schwalbe, Harald

Publication type:

Article

Photo-Tethers for the (Multi-)Cyclic, Conformational Caging of Long Oligonucleotides.

Published in:

Angewandte Chemie International Edition, 2017, v. 56, n. 1, p. 359, doi. 10.1002/anie.201610025

By:

Seyfried, Patrick;
Eiden, Laura;
Grebenovsky, Nikolai;
Mayer, Günter;
Heckel, Alexander

Publication type:

Article

Three-Dimensional Control of DNA Hybridization by Orthogonal Two-Color Two-Photon Uncaging.

Published in:

Angewandte Chemie International Edition, 2016, v. 55, n. 31, p. 8948, doi. 10.1002/anie.201603281

By:

Fichte, Manuela A. H.;
Weyel, Xenia M. M.;
Junek, Stephan;
Schäfer, Florian;
Herbivo, Cyril;
Goeldner, Maurice;
Specht, Alexandre;
Wachtveitl, Josef;
Heckel, Alexander

Publication type:

Article

Photoresponsive Formation of an Intermolecular Minimal G-Quadruplex Motif.

Published in:

Angewandte Chemie International Edition, 2016, v. 55, n. 8, p. 2738, doi. 10.1002/anie.201510269

By:

Thevarpadam, Julie;
Bessi, Irene;
Binas, Oliver;
Gonçalves, Diana P. N.;
Slavov, Chavdar;
Jonker, Hendrik R. A.;
Richter, Christian;
Wachtveitl, Josef;
Schwalbe, Harald;
Heckel, Alexander

Publication type:

Article

Three-Dimensional Protein Networks Assembled by Two-Photon Activation.

Published in:

Angewandte Chemie International Edition, 2014, v. 53, n. 22, p. 5680, doi. 10.1002/anie.201309930

By:

Gatterdam, Volker;
Ramadass, Radhan;
Stoess, Tatjana;
Fichte, Manuela A. H.;
Wachtveitl, Josef;
Heckel, Alexander;
Tampé, Robert

Publication type:

Article

Back Cover: Three-Dimensional Protein Networks Assembled by Two-Photon Activation (Angew. Chem. Int. Ed. 22/2014).

Published in:

Angewandte Chemie International Edition, 2014, v. 53, n. 22, p. 5712, doi. 10.1002/anie.201401149

By:

Gatterdam, Volker;
Ramadass, Radhan;
Stoess, Tatjana;
Fichte, Manuela A. H.;
Wachtveitl, Josef;
Heckel, Alexander;
Tampé, Robert

Publication type:

Article

Influence of the Absolute Configuration of NPE-Caged Cytosine on DNA Single Base Pair Stability.

Published in:

Angewandte Chemie International Edition, 2014, v. 53, n. 4, p. 1072, doi. 10.1002/anie.201307852

By:

Steinert, Hannah S.;
Schäfer, Florian;
Jonker, Hendrik R. A.;
Heckel, Alexander;
Schwalbe, Harald

Publication type:

Article

Regulating Angiogenesis with Light-Inducible AntimiRs.

Published in:

Angewandte Chemie International Edition, 2013, v. 52, n. 51, p. 13558, doi. 10.1002/anie.201307502

By:

Schäfer, Florian;
Wagner, Jasmin;
Knau, Andrea;
Dimmeler, Stefanie;
Heckel, Alexander

Publication type:

Article

Aptamer-Guided Caging for Selective Masking of Protein Domains.

Published in:

Angewandte Chemie International Edition, 2013, v. 52, n. 45, p. 11912, doi. 10.1002/anie.201306686

By:

Rohrbach, Falk;
Schäfer, Florian;
Fichte, Manuela A. H.;
Pfeiffer, Franziska;
Müller, Jens;
Pötzsch, Bernd;
Heckel, Alexander;
Mayer, Günter

Publication type:

Article

Inside Back Cover: Aptamer-Guided Caging for Selective Masking of Protein Domains (Angew. Chem. Int. Ed. 45/2013).

Published in:

Angewandte Chemie International Edition, 2013, v. 52, n. 45, p. 11941, doi. 10.1002/anie.201308371

By:

Rohrbach, Falk;
Schäfer, Florian;
Fichte, Manuela A. H.;
Pfeiffer, Franziska;
Müller, Jens;
Pötzsch, Bernd;
Heckel, Alexander;
Mayer, Günter

Publication type:

Article

Comparison of the duplex-destabilizing effects of nucleobase-caged oligonucleotides.

Published in:

Analytical & Bioanalytical Chemistry, 2011, v. 399, n. 1, p. 441, doi. 10.1007/s00216-010-4274-7

By:

Rodrigues-Correia, Alexandre;
Koeppel, Martin B.;
Schäfer, Florian;
Joshi, K. B.;
Mack, Timo;
Heckel, Alexander

Publication type:

Article

Photon Cascade with Clip-On Fluorophores.

Published in:

ChemPhysChem, 2011, v. 12, n. 11, p. 2073, doi. 10.1002/cphc.201100295

By:

Friedrich, Felix;
Heckel, Alexander

Publication type:

Article