Works by Hecht, Stephen S.

Results: 163

Syntheses of anti -7,8,9,10-Tetrahydro-11-, and 12-Methylbenzo[ A ]Pyrene-7,8-DIOL-9, 10-Epoxides: Identification and Comparison of DNA Adduct Formation with Calf-Thymus DNA in vitro.

Published in:

Polycyclic Aromatic Compounds, 2000, v. 17, n. 1-4, p. 63, doi. 10.1080/10406639908020602

By:

Lin, Jyh-ming;
Desai, Dhimant;
Chung, Lehua;
Hecht, Stephen S.;
Amin, Shantu

Publication type:

Article

Tumorigenicity of Fjord Region Diol Epoxides of Polycyclic Aromatic Hydrocarbons.

Published in:

Polycyclic Aromatic Compounds, 1996, v. 11, n. 1-4, p. 365, doi. 10.1080/10406639608544688

By:

Amin, Shantu;
Desai, Dhimant;
El-Bayoumy, Karam;
Rivenson, Abraham;
Hecht, Stephen S.

Publication type:

Article

Detection of Polynuclear Aromatic Hydrocarbon Diol Epoxide-Derived DNA and Globin Adducts in Humans by Gas Chromatography-Mass Spectrometry.

Published in:

Polycyclic Aromatic Compounds, 1996, v. 10, n. 1-4, p. 315, doi. 10.1080/10406639608034712

By:

Melikian, Assieh A.;
Sun, Peng;
Coleman, Stuart;
Murphy, Sharon E.;
Amin, Shantu;
Hecht, Stephen S.

Publication type:

Article

Metabolic Activation of Chrysene by Human Hepatic and Pulmonary Cytochrome P450 Enzymes.

Published in:

Polycyclic Aromatic Compounds, 1996, v. 10, n. 1-4, p. 59, doi. 10.1080/10406639608034680

By:

Koehl, Werner;
Amin, Shantu;
Yamazaki, Hiroshi;
Ueng, Yune-Fang;
Tateishi, Tomonuri;
Guengerich, F. Peter;
Hecht, Stephen S.

Publication type:

Article

Research on cruciferous vegetables, indole-3-carbinol, and cancer prevention: A tribute to Lee W. Wattenberg.

Published in:

Molecular Nutrition & Food Research, 2016, v. 60, n. 6, p. 1228, doi. 10.1002/mnfr.201500889

By:

Fujioka, Naomi;
Fritz, Vincent;
Upadhyaya, Pramod;
Kassie, Fekadu;
Hecht, Stephen S.

Publication type:

Article

Self-reported Tobacco use does not correlate with carcinogen exposure in smokers with head and neck cancer.

Published in:

Laryngoscope, 2015, v. 125, n. 8, p. 1844, doi. 10.1002/lary.25290

By:

Khariwala, Samir S.;
Carmella, Steven G.;
Stepanov, Irina;
Bandyopadhyay, Dipankar;
Nelson, Heather H.;
Yueh, Bevan;
Hatsukami, Dorothy K.;
Hecht, Stephen S.

Publication type:

Article

Lung Tumorigenesis Suppressing Effects of a Commercial Kava Extract and Its Selected Compounds in A/J Mice.

Published in:

2011

By:

Johnson, Thomas E.;
Hermanson, David;
Wang, Lei;
Kassie, Fekadu;
Upadhyaya, Pramod;
O'Sullivan, Michael G.;
Hecht, Stephen S.;
Lu, Junxuan;
Xing, Chengguo

Publication type:

Journal Article

Lung Tumorigenesis Suppressing Effects of a Commercial Kava Extract and Its Selected Compounds in A/J Mice.

Published in:

American Journal of Chinese Medicine, 2011, v. 39, n. 4, p. 727, doi. 10.1142/S0192415X11009202

By:

Johnson, Thomas E.;
Hermanson, David;
Wang, Lei;
Kassie, Fekadu;
Upadhyaya, Pramod;
O'Sullivan, Michael G.;
Hecht, Stephen S.;
Lu, Junxuan;
Xing, Chengguo

Publication type:

Article

An update on the formation in tobacco, toxicity and carcinogenicity of Nʹ-nitrosonornicotine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.

Published in:

Carcinogenesis, 2024, v. 45, n. 5, p. 275, doi. 10.1093/carcin/bgae018

By:

Peterson, Lisa A;
Stanfill, Stephen B;
Hecht, Stephen S

Publication type:

Article

Increased acrolein–DNA adducts in buccal brushings of e-cigarette users.

Published in:

Carcinogenesis, 2022, v. 43, n. 5, p. 437, doi. 10.1093/carcin/bgac026

By:

Cheng, Guang;
Guo, Jiehong;
Carmella, Steven G;
Lindgren, Bruce;
Ikuemonisan, Joshua;
Niesen, Brittany;
Jensen, Joni;
Hatsukami, Dorothy K;
Balbo, Silvia;
Hecht, Stephen S

Publication type:

Article

Characterization of adductomic totality of NNK, (R)-NNAL and (S)-NNAL in A/J mice, and their correlations with distinct lung carcinogenicity.

Published in:

Carcinogenesis, 2022, v. 43, n. 2, p. 170, doi. 10.1093/carcin/bgab113

By:

Hu, Qi;
Upadhyaya, Pramod;
Hecht, Stephen S;
Aly, F Zahra;
Huo, Zhiguang;
Xing, Chengguo

Publication type:

Article

Cigarette smoking enhances the metabolic activation of the polycyclic aromatic hydrocarbon phenanthrene in humans.

Published in:

Carcinogenesis, 2021, v. 42, n. 4, p. 570, doi. 10.1093/carcin/bgaa137

By:

Luo, Kai;
Luo, Xianghua;
Cao, Wenhao;
Hochalter, J Bradley;
Paiano, Viviana;
Sipe, Christopher J;
Carmella, Steven G;
Murphy, Sharon E;
Jensen, Joni;
Lam, Stephen;
Golin, Andrew P;
Bergstrom, Lori;
Midthun, David;
Fujioka, Naomi;
Hatsukami, Dorothy;
Hecht, Stephen S

Publication type:

Article

Methyl DNA phosphate adduct formation in lung tumor tissue and adjacent normal tissue of lung cancer patients.

Published in:

Carcinogenesis, 2019, v. 40, n. 11, p. 1387, doi. 10.1093/carcin/bgz053

By:

Ma, Bin;
Villalta, Peter W;
Hochalter, J Bradley;
Stepanov, Irina;
Hecht, Stephen S

Publication type:

Article

Prediagnostic levels of urinary 8-epi-prostaglandin F2α and prostaglandin E2 metabolite, biomarkers of oxidative damage and inflammation, and risk of hepatocellular carcinoma.

Published in:

Carcinogenesis, 2019, v. 40, n. 8, p. 989, doi. 10.1093/carcin/bgy180

By:

Yuan, Jian-Min;
Grouls, Menno;
Carmella, Steven G;
Wang, Renwei;
Heskin, Alisa;
Jiang, Yang;
Tan, Yu-Ting;
Adams-Haduch, Jennifer;
Gao, Yu-Tang;
Hecht, Stephen S

Publication type:

Article

Relationship of the oxidative damage biomarker 8-epiprostaglandin F2 to risk of lung cancer development in the Shanghai Cohort Study.

Published in:

Carcinogenesis, 2018, v. 39, n. 7, p. 948, doi. 10.1093/carcin/bgy060

By:

Yuan, Jian-Min;
Carmella, Steven G;
Wang, Renwei;
Tan, Yu-Ting;
Adams-Haduch, Jennifer;
Gao, Yu-Tang;
Hecht, Stephen S

Publication type:

Article

Identification of more than 100 structurally unique DNA-phosphate adducts formed during rat lung carcinogenesis by the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone.

Published in:

Carcinogenesis, 2018, v. 39, n. 2, p. 232, doi. 10.1093/carcin/bgx135

By:

Bin Ma;
Zarth, Adam T.;
Carlson, Erik S.;
Villalta, Peter W.;
Upadhyaya, Pramod;
Stepanov, Irina;
Hecht, Stephen S.

Publication type:

Article

CYP2A6 genetic polymorphisms and biomarkers of tobacco smoke constituents in relation to risk of lung cancer in the Singapore Chinese Health Study.

Published in:

Carcinogenesis, 2017, v. 38, n. 4, p. 411, doi. 10.1093/carcin/bgx012

By:

Jian-Min Yuan;
Nelson, Heather H.;
Carmella, Steven G.;
Renwei Wang;
Kuriger-Laber, Jacquelyn;
Aizhen Jin;
Adams-Haduch, Jennifer;
Hecht, Stephen S.;
Woon-Puay Koh;
Murphy, Sharon E.

Publication type:

Article

Carcinogenicity and DNA adduct formation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in F-344 rats.

Published in:

Carcinogenesis, 2014, v. 35, n. 12, p. 2798, doi. 10.1093/carcin/bgu204

By:

Balbo, Silvia;
Johnson, Charles S.;
Kovi, Ramesh C.;
James-Yi, Sandra A.;
O’Sullivan, M. Gerard;
Wang, Mingyao;
Le, Chap T.;
Khariwala, Samir S.;
Upadhyaya, Pramod;
Hecht, Stephen S.

Publication type:

Article

Dihydromethysticin from kava blocks tobacco carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis and differentially reduces DNA damage in A/J mice.

Published in:

Carcinogenesis, 2014, v. 35, n. 10, p. 2365, doi. 10.1093/carcin/bgu149

By:

Narayanapillai, Sreekanth C.;
Balbo, Silvia;
Leitzman, Pablo;
Grill, Alex E.;
Upadhyaya, Pramod;
Shaik, Ahmad Ali;
Zhou, Bo;
O’Sullivan, M. Gerard;
Peterson, Lisa A.;
Lu, Junxuan;
Hecht, Stephen S.;
Xing, Chengguo

Publication type:

Article

Urinary metabolites of a polycyclic aromatic hydrocarbon and volatile organic compounds in relation to lung cancer development in lifelong never smokers in the Shanghai Cohort Study.

Published in:

Carcinogenesis, 2014, v. 35, n. 2, p. 339, doi. 10.1093/carcin/bgt352

By:

Yuan, Jian-Min;
Butler, Lesley M.;
Gao, Yu-Tang;
Murphy, Sharon E.;
Carmella, Steven G.;
Wang, Renwei;
Nelson, Heather H.;
Hecht, Stephen S.

Publication type:

Article

(S)-N′-Nitrosonornicotine, a constituent of smokeless tobacco, is a powerful oral cavity carcinogen in rats.

Published in:

Carcinogenesis, 2013, v. 34, n. 9, p. 2178, doi. 10.1093/carcin/bgt162

By:

Balbo, Silvia;
James-Yi, Sandra;
Johnson, Charles S.;
O’Sullivan, Michael G.;
Stepanov, Irina;
Wang, Mingyao;
Bandyopadhyay, Dipankar;
Kassie, Fekadu;
Carmella, Steven;
Upadhyaya, Pramod;
Hecht, Stephen S.

Publication type:

Article

Urinary levels of volatile organic carcinogen and toxicant biomarkers in relation to lung cancer development in smokers.

Published in:

Carcinogenesis, 2012, v. 33, n. 4, p. 804, doi. 10.1093/carcin/bgs026

By:

Yuan, Jian-Min;
Gao, Yu-Tang;
Wang, Renwei;
Chen, Menglan;
Carmella, Steven G.;
Hecht, Stephen S.

Publication type:

Article

Modulation of the metabolism of airborne pollutants by glucoraphanin-rich and sulforaphane-rich broccoli sprout beverages in Qidong, China.

Published in:

Carcinogenesis, 2012, v. 33, n. 1, p. 101, doi. 10.1093/carcin/bgr229

By:

Kensler, Thomas W.;
Ng, Derek;
Carmella, Steven G.;
Chen, Menglan;
Jacobson, Lisa P.;
Muñoz, Alvaro;
Egner, Patricia A.;
Chen, Jian Guo;
Qian, Geng Sun;
Chen, Tao Yang;
Fahey, Jed W.;
Talalay, Paul;
Groopman, John D.;
Yuan, Jian-Min;
Hecht, Stephen S.

Publication type:

Article

Urinary levels of the tobacco-specific carcinogen N′-nitrosonornicotine and its glucuronide are strongly associated with esophageal cancer risk in smokers.

Published in:

Carcinogenesis, 2011, v. 32, n. 9, p. 1366, doi. 10.1093/carcin/bgr125

By:

Yuan, Jian-Min;
Knezevich, Aleksandar D.;
Wang, Renwei;
Gao, Yu-Tang;
Hecht, Stephen S.;
Stepanov, Irina

Publication type:

Article

Inhibition of lung carcinogenesis and critical cancer-related signaling pathways by N-acetyl-S-(N-2-phenethylthiocarbamoyl)-l-cysteine, indole-3-carbinol and myo-inositol, alone and in combination.

Published in:

Carcinogenesis, 2010, v. 31, n. 9, p. 1634, doi. 10.1093/carcin/bgq139

By:

Kassie, Fekadu;
Melkamu, Tamene;
Endalew, Abaineh;
Upadhyaya, Pramod;
Xianghua Luo;
Hecht, Stephen S.

Publication type:

Article

Inhibition of vinyl carbamate-induced pulmonary adenocarcinoma by indole-3-carbinol and myo-inositol in A/J mice.

Published in:

Carcinogenesis, 2010, v. 31, n. 2, p. 239, doi. 10.1093/carcin/bgp174

By:

Kassie, Fekadu;
Kalscheuer, Stephen;
Matise, Ilze;
Ma, Linan;
Melkamu, Tamene;
Upadhyaya, Pramod;
Hecht, Stephen S.

Publication type:

Article

Analysis of phenanthrene diol epoxide mercapturic acid detoxification products in human urine: relevance to molecular epidemiology studies of glutathione S-transferase polymorphisms.

Published in:

Carcinogenesis, 2008, v. 29, n. 5, p. 937, doi. 10.1093/carcin/bgn015

By:

Stephen S. Hecht;
Peter W. Villalta;
J.Bradley Hochalter

Publication type:

Article

Chemopreventive agents modulate the protein expression profile of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone plus benzo[a]pyrene-induced lung tumors in A/J mice.

Published in:

Carcinogenesis, 2008, v. 29, n. 3, p. 610

By:

Fekadu Kassie;
Lorraine B. Anderson;
LeeAnn Higgins;
Yunqian Pan;
Ilze Matise;
Mesfin Negia;
Pramod Upadhyaya;
Mingyao Wang;
Stephen S. Hecht

Publication type:

Article

Carcinogenicity studies of inhaled cigarette smoke in laboratory animals: old and new.

Published in:

Carcinogenesis, 2005, v. 26, n. 9, p. 1488, doi. 10.1093/carcin/bgi148

By:

Stephen S. Hecht

Publication type:

Article

DNA damage in human oral cells induced by use of e‐cigarettes.

Published in:

Drug Testing & Analysis, 2023, v. 15, n. 10, p. 1189, doi. 10.1002/dta.3375

By:

Guo, Jiehong;
Hecht, Stephen S.

Publication type:

Article

Key Characteristics of Carcinogens as a Basis for Organizing Data on Mechanisms of Carcinogenesis.

Published in:

Environmental Health Perspectives, 2016, v. 124, n. 6, p. 713, doi. 10.1289/ehp.1509912

By:

Smith, Martyn T.;
Guyton, Kathryn Z.;
Gibbons, Catherine F.;
Fritz, Jason M.;
Portier, Christopher J.;
Rusyn, Ivan;
DeMarini, David M.;
Caldwell, Jane C.;
Kavlock, Robert J.;
Lambert, Paul F.;
Hecht, Stephen S.;
Bucher, John R.;
Stewart, Bernard W.;
Baan, Robert A.;
Cogliano, Vincent J.;
Straif, Kurt

Publication type:

Article

Children's Exposure to Environmental Tobacco Smoke: Using Diverse Exposure Metrics to Document Ethnic/Racial Differences.

Published in:

Environmental Health Perspectives, 2004, v. 112, n. 3, p. 392, doi. 10.1289/ehp.6473

By:

Sexton, Ken;
Adgate, John L.;
Church, Timothy R.;
Hecht, Stephen S.;
Ramachandran, Gurumurthy;
Greaves, Ian A.;
Fredrickson, Ann L.;
Ryan, Andrew D.;
Carmella, Steven G.;
Geisser, Mindy S.

Publication type:

Article

Perspective: Tackling the real issues.

Published in:

2011

By:

Hecht, Stephen S.

Publication type:

Opinion

Clues to the etiology of childhood brain cancer: N-nitroso compounds, polyomaviruses, and other factors of interest.

Published in:

2001

By:

Gurney, James G.;
Smith, Malcolm A.;
Olshan, Andrew F.;
Hecht, Stephen S.;
Kasum, Christine M.;
Gurney, J G;
Smith, M A;
Olshan, A F;
Hecht, S S;
Kasum, C M

Publication type:

journal article

Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers.

Published in:

Oncogene, 2002, v. 21, n. 48, p. 7435, doi. 10.1038/sj.onc.1205803

By:

Pfeifer, Gerd P.;
Denissenko, Mikhail F.;
Olivier, Magali;
Tretyakova, Natalia;
Hecht, Stephen S.;
Hainaut, Pierre

Publication type:

Article

Tobacco-specific nitrosamines in smokeless tobacco products marketed in India.

Published in:

International Journal of Cancer, 2005, v. 116, n. 1, p. 16, doi. 10.1002/ijc.20966

By:

Stepanov, Irina;
Hecht, Stephen S.;
Ramakrishnan, Sreevidya;
Gupta, Prakash C.

Publication type:

Article

Metabolites of the Polycyclic Aromatic Hydrocarbon Phenanthrene in the Urine of Cigarette Smokers from Five Ethnic Groups with Differing Risks for Lung Cancer.

Published in:

PLoS ONE, 2016, v. 11, n. 6, p. 1, doi. 10.1371/journal.pone.0156203

By:

Patel, Yesha M.;
Park, Sungshim L.;
Carmella, Steven G.;
Paiano, Viviana;
Olvera, Natalie;
Stram, Daniel O.;
Haiman, Christopher A.;
Le Marchand, Loic;
Hecht, Stephen S.

Publication type:

Article

Benzene Uptake and Glutathione S-transferase T1 Status as Determinants of S-Phenylmercapturic Acid in Cigarette Smokers in the Multiethnic Cohort.

Published in:

PLoS ONE, 2016, v. 11, n. 3, p. 1, doi. 10.1371/journal.pone.0150641

By:

Haiman, Christopher A.;
Patel, Yesha M.;
Stram, Daniel O.;
Carmella, Steven G.;
Chen, Menglan;
Wilkens, Lynne R.;
Le Marchand, Loic;
Hecht, Stephen S.

Publication type:

Article

Elevated levels of 1-hydroxypyrene and N′-nitrosonornicotine in smokers with head and neck cancer: A matched control study.

Published in:

Head & Neck, 2013, v. 35, n. 8, p. 1096, doi. 10.1002/hed.23085

By:

Khariwala, Samir S.;
Carmella, Steven G.;
Stepanov, Irina;
Fernandes, Patricia;
Lassig, Amy Anne;
Yueh, Bevan;
Hatsukami, Dorothy;
Hecht, Stephen S.

Publication type:

Article

Tobacco carcinogen metabolites and DNA adducts as biomarkers in Head and Neck cancer: Potential screening tools and prognostic indicators.

Published in:

Head & Neck, 2012, v. 34, n. 3, p. 441, doi. 10.1002/hed.21705

By:

Khariwala, Samir S.;
Hatsukami, Dorothy;
Hecht, Stephen S.;
Myers, Jeffrey N.

Publication type:

Article

Metastasis to the F344 Rat Pancreas from Lung Cancer Induced by 4-(Methylnitrosamino)- 1-(3-pyridyl)-1-butanone and Enantiomers of Its Metabolite 4-(Methylnitrosamino)-1-(3-pyridyl)- 1-butanol, Constituents of Tobacco Products.

Published in:

Toxicologic Pathology, 2018, v. 46, n. 2, p. 184, doi. 10.1177/0192623317751573

By:

Kovi, Ramesh C.;
Johnson, Charles S.;
Balbo, Silvia;
Hecht, Stephen S.;
O’Sullivan, M. Gerard

Publication type:

Article

Tobacco biomarkers and genetic/epigenetic analysis to investigate ethnic/racial differences in lung cancer risk among smokers.

Published in:

NPJ Precision Oncology, 2018, v. 2, n. 1, p. N.PAG, doi. 10.1038/s41698-018-0057-y

By:

Murphy, Sharon E.;
Park, Sungshim Lani;
Balbo, Silvia;
Haiman, Christopher A.;
Hatsukami, Dorothy K.;
Patel, Yesha;
Peterson, Lisa A.;
Stepanov, Irina;
Stram, Daniel O.;
Tretyakova, Natalia;
Hecht, Stephen S.;
Le Marchand, Loïc

Publication type:

Article

Chemoprevention of lung carcinogenesis in addicted smokers and ex-smokers.

Published in:

2009

By:

Hecht, Stephen S.;
Kassie, Fekadu;
Hatsukami, Dorothy K.

Publication type:

journal article

TOBACCO CARCINOGENS, THEIR BIOMARKERS AND TOBACCO-INDUCED CANCER.

Published in:

2004

By:

Hecht, Stephen S.

Publication type:

Correction Notice

TOBACCO CARCINOGENS, THEIR BIOMARKERS AND TOBACCO-INDUCED CANCER.

Published in:

Nature Reviews Cancer, 2003, v. 3, n. 10, p. 733, doi. 10.1038/nrc1190

By:

Hecht, Stephen S.

Publication type:

Article

Deguelin as a Chemopreventive Agent in Mouse Lung Tumorigenesis Induced by Tobacco Smoke Carcinogens.

Published in:

2005

By:

Hecht, Stephen S.

Publication type:

Editorial

Polycyclic Aromatic Hydrocarbons and Pancreatic Cancer: An Analysis of the Blood Biomarker, r -1, t -2,3, c -4-Tetrahydroxy-1,2,3,4-tetrahydrophenanthrene and Selected Metabolism Gene SNPs.

Published in:

Nutrients, 2024, v. 16, n. 5, p. 688, doi. 10.3390/nu16050688

By:

Nguyen, Sierra;
Carlson, Heather;
Yoder, Andrea;
Bamlet, William R.;
Oberg, Ann L.;
Petersen, Gloria M.;
Carmella, Steven G.;
Hecht, Stephen S.;
Jansen, Rick J.

Publication type:

Article

Reduced nicotine content cigarettes and use of alternative nicotine products: exploratory trial.

Published in:

Addiction, 2017, v. 112, n. 1, p. 156, doi. 10.1111/add.13603

By:

Hatsukami, Dorothy K.;
Luo, Xianghua;
Dick, Laura;
Kangkum, Margarita;
Allen, Sharon S.;
Murphy, Sharon E.;
Hecht, Stephen S.;
Shields, Peter G.;
al'Absi, Mustafa

Publication type:

Article

Reduced nicotine content cigarettes: effects on toxicant exposure, dependence and cessation.

Published in:

Addiction, 2010, v. 105, n. 2, p. 343, doi. 10.1111/j.1360-0443.2009.02780.x

By:

Hatsukami, Dorothy K.;
Kotlyar, Michael;
Hertsgaard, Louise A.;
Zhang, Yan;
Carmella, Steven G.;
Jensen, Joni A.;
Allen, Sharon S.;
Shields, Peter G.;
Murphy, Sharon E.;
Stepanov, Irina;
Hecht, Stephen S.

Publication type:

Article

Effects of cessation of cigarette smoking on eicosanoid biomarkers of inflammation and oxidative damage.

Published in:

PLoS ONE, 2019, v. 14, n. 6, p. 1, doi. 10.1371/journal.pone.0218386

By:

McElroy, Joseph P.;
Carmella, Steven G.;
Heskin, Alisa K.;
Tang, Mei Kuen;
Murphy, Sharon E.;
Reisinger, Sarah A.;
Jensen, Joni A.;
Hatsukami, Dorothy K.;
Hecht, Stephen S.;
Shields, Peter G.

Publication type:

Article