Works by Heath, William R.

Results: 82

Autoimmune diabetes as a consequence of locally produced interleukin-2.

Published in:

Nature, 1992, v. 359, n. 6395, p. 547, doi. 10.1038/359547a0

By:

Heath, William R.;
Allison, Janette

Publication type:

Article

Cerebral Malaria in Mouse and Man.

Published in:

Frontiers in Immunology, 2018, p. N.PAG, doi. 10.3389/fimmu.2018.02016

By:

Ghazanfari, Nazanin;
Mueller, Scott N.;
Heath, William R.

Publication type:

Article

A role for plasmacytoid dendritic cells in the rapid IL-18-dependent activation of NK cells following HSV-1 infection.

Published in:

European Journal of Immunology, 2007, v. 37, n. 5, p. 1334, doi. 10.1002/eji.200636362

By:

Barr, Daniel P.;
Belz, Gabrielle T.;
Reading, Patrick C.;
Wojtasiak, Magdalena;
Whitney, Paul G.;
Heath, William R.;
Carbone, Francis R.;
Brooks, Andrew G.

Publication type:

Article

Bone marrow-derived cells expand memory CD8.

Published in:

European Journal of Immunology, 2006, v. 36, n. 2, p. 327, doi. 10.1002/eji.200535432

By:

Belz, Gabrielle T.;
Wilson, Nicholas S.;
Smith, Christopher M.;
Mount, Adele M.;
Carbone, Francis R.;
Heath, William R.

Publication type:

Article

Induction of T-cell-mediated skin disease specific for antigen transgenically expressed in keratinocytes.

Published in:

European Journal of Immunology, 2003, v. 33, n. 7, p. 1879, doi. 10.1002/eji.200323630

By:

Azukizawa, Hiroaki;
Kosaka, Hiroshi;
Sano, Shigetoshi;
Heath, William R.;
Takahashi, Isao;
Gao, Xing-Hua;
Sumikawa, Yasuyuki;
Okabe, Masaru;
Yoshikawa, Kunihiko;
Itami, Satoshi

Publication type:

Article

Virus infection expands a biased subset of T cells that bind tetrameric class I peptide complexes.

Published in:

European Journal of Immunology, 2003, v. 33, n. 6, p. 1557, doi. 10.1002/eji.200323715

By:

Coles, Richard M.;
Jones, Claerwen M.;
Brooks, Andrew G.;
Cameron, Paul U.;
Heath, William R.;
Carbone, Francis R.

Publication type:

Article

Constitutive, but not inflammatory, cross-presentation is disabled in the pancreas of young mice.

Published in:

European Journal of Immunology, 2002, v. 32, n. 4, p. 1044, doi. 10.1002/1521-4141(200204)32:4<1044::AID-IMMU1044>3.0.CO;2-B

By:

Mintern, Justine D.;
Sutherland, Robyn M.;
Lew, Andrew M.;
Shortman, Ken;
Carbone, Francis R.;
Heath, William R.

Publication type:

Article

Effect of pre-existing cytotoxic T lymphocytes on therapeutic vaccines.

Published in:

European Journal of Immunology, 2000, v. 30, n. 2, p. 671, doi. 10.1002/1521-4141(200002)30:2<671::AID-IMMU671>3.0.CO;2-H

By:

Sherritt, Martina A.;
Gardner, Joy;
Elliott, Suzanne L.;
Schmidt, Christopher;
Purdie, David;
Deliyannis, Georgia;
Heath, William R.;
Suhrbier, Andreas

Publication type:

Article

The threshold for autoimmune T cell killing is influenced by B7-1.

Published in:

European Journal of Immunology, 1998, v. 28, n. 3, p. 949, doi. 10.1002/(SICI)1521-4141(199803)28:03<949::AID-IMMU949>3.0.CO;2-H

By:

Allison, Janette;
Stephens, Leigh A.;
Kay, Thomas W.;
Kurts, Christian;
Heath, William R.;
Miller, Jacques F. A. P.;
Krummel, Matthew F.

Publication type:

Article

Antigen-specific CD8.

Published in:

European Journal of Immunology, 1997, v. 27, n. 9, p. 2310, doi. 10.1002/eji.1830270927

By:

Cose, Stephen C.;
Jones, Claeroen M.;
Wallace, Morgan E.;
Heath, William R.;
Carbone, Francis R.

Publication type:

Article

Peripheral deletion of autoreactive CD8.

Published in:

European Journal of Immunology, 1995, v. 25, n. 7, p. 1932, doi. 10.1002/eji.1830250721

By:

Bertolino, Patrick;
Heath, William R.;
Hardy, Charles L.;
Morahan, Grant;
Miller, Jacques F. A. P.

Publication type:

Article

Expression of two T cell receptor α chains on the surface of normal murine T cells.

Published in:

European Journal of Immunology, 1995, v. 25, n. 6, p. 1617, doi. 10.1002/eji.1830250622

By:

Heath, William R.;
Carbone, Francis R.;
Bertolino, Patrick;
Kelly, Jannice;
Cose, Steve;
Miller, Jacques F. A. P.

Publication type:

Article

Peptide antagonists that promote positive selection are inefficient at T cell activation and thymocyte deletion.

Published in:

European Journal of Immunology, 1994, v. 24, n. 10, p. 2452, doi. 10.1002/eji.1830241029

By:

Barnden, Megan J.;
Heath, William R.;
Rodda, Stuart;
Carbone, Francis R.

Publication type:

Article

Cell-type-specific recognition of allogeneic cells by alloreactive cytotoxic T cells: A consequence of peptide-dependent allorecognition.

Published in:

European Journal of Immunology, 1991, v. 21, n. 1, p. 153, doi. 10.1002/eji.1830210123

By:

Heath, William R.;
Sherman, Linda A.

Publication type:

Article

A hepatic network of dendritic cells mediates CD4 T cell help outside lymphoid organs.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-45612-5

By:

English, Kieran;
Kwan, Rain;
Holz, Lauren E.;
McGuffog, Claire;
Krol, Jelte M. M.;
Kempe, Daryan;
Kaisho, Tsuneyasu;
Heath, William R.;
Lisowski, Leszek;
Biro, Maté;
McCaughan, Geoffrey W.;
Bowen, David G.;
Bertolino, Patrick

Publication type:

Article

Blood-Stage Plasmodium berghei Infection Generates a Potent, Specific CD8+ T-Cell Response Despite Residence Largely in Cells Lacking MHC I Processing Machinery.

Published in:

Journal of Infectious Diseases, 2011, v. 204, n. 12, p. 1989, doi. 10.1093/infdis/jir656

By:

Lau, Lei Shong;
Ruiz, Daniel Fernandez;
Davey, Gayle M.;
de Koning-Ward, Tania F.;
Papenfuss, Anthony T.;
Carbone, Francis R.;
Brooks, Andrew G.;
Crabb, Brendan S.;
Heath, William R.

Publication type:

Article

Reactive murine lymph nodes uniquely permit parenchymal access for T cells that enter via the afferent lymphatics.

Published in:

Journal of Pathology, 2012, v. 226, n. 5, p. 806, doi. 10.1002/path.3975

By:

Eidsmo, Liv;
Stock, Angus T;
Heath, William R;
Bedoui, Sammy;
Carbone, Francis R

Publication type:

Article

Different patterns of peripheral migration by memory CD4+ and CD8+ T cells.

Published in:

Nature, 2011, v. 477, n. 7363, p. 216, doi. 10.1038/nature10339

By:

Gebhardt, Thomas;
Whitney, Paul G.;
Zaid, Ali;
Mackay, Laura K.;
Brooks, Andrew G.;
Heath, William R.;
Carbone, Francis R.;
Mueller, Scott N.

Publication type:

Article

Using Full‐Spectrum Flow Cytometry to Phenotype Memory T and NKT Cell Subsets with Optimized Tissue‐Specific Preparation Protocols.

Published in:

Current Protocols, 2022, v. 2, n. 7, p. 1, doi. 10.1002/cpz1.482

By:

Farrand, Kathryn;
Holz, Lauren E.;
Ferrer‐Font, Laura;
Wilson, Michael D.;
Ganley, Mitch;
Minnell, Jordan J.;
Tang, Ching‐Wen;
Painter, Gavin F.;
Heath, William R.;
Hermans, Ian F.;
Burn, Olivia K.

Publication type:

Article

Extrafollicular CD4 T cell-derived IL-10 functions rapidly and transiently to support anti-Plasmodium humoral immunity.

Published in:

PLoS Pathogens, 2021, v. 17, n. 2, p. 1, doi. 10.1371/journal.ppat.1009288

By:

Surette, Fionna A.;
Guthmiller, Jenna J.;
Li, Lei;
Sturtz, Alexandria J.;
Vijay, Rahul;
Pope, Rosemary L.;
McClellan, Brandon L.;
Pack, Angela D.;
Zander, Ryan A.;
Shao, Peng;
Lan, Linda Yu-Ling;
Fernandez-Ruiz, Daniel;
Heath, William R.;
Wilson, Patrick C.;
Butler, Noah S.

Publication type:

Article

Unresponsiveness to inhaled antigen is governed by conventional dendritic cells and overridden during infection by monocytes.

Published in:

Science Immunology, 2020, v. 5, n. 52, p. 1, doi. 10.1126/sciimmunol.abb5439

By:

Bedford, James G.;
Heinlein, Melanie;
Garnham, Alexandra L.;
Nguyen, Thi H. O.;
Loudovaris, Tom;
Ge, Chenghao;
Mannering, Stuart I.;
Elliott, Michael;
Tangye, Stuart G.;
Kedzierska, Katherine;
Gray, Daniel H. D.;
Heath, William R.;
Wakim, Linda M.

Publication type:

Article

Migratory CD11b+ conventional dendritic cells induce T follicular helper cell-dependent antibody responses.

Published in:

Science Immunology, 2017, v. 2, n. 18, p. 1, doi. 10.1126/sciimmunol.aam9169

By:

Krishnaswamy, Jayendra Kumar;
Gowthaman, Uthaman;
Biyan Zhang;
Mattsson, Johan;
Szeponik, Louis;
Dong Liu;
Renee Wu;
White, Theresa;
Calabro, Samuele;
Lan Xu;
Collet, Magalie A.;
Yurieva, Marina;
Alsén, Samuel;
Fogelstrand, Per;
Walter, Anne;
Heath, William R.;
Mueller, Scott N.;
Yrlid, Ulf;
Williams, Adam;
Eisenbarth, Stephanie C.

Publication type:

Article

Resident memory CD8+ T cells in the upper respiratory tract prevent pulmonary influenza virus infection.

Published in:

Science Immunology, 2017, v. 2, n. 12, p. 1, doi. 10.1126/sciimmunol.aam6970

By:

Pizzolla, Angela;
O. Nguyen, Thi H.;
Smith, Jeffrey M.;
Brooks, Andrew G.;
Kedzieska, Katherine;
Heath, William R.;
Reading, Patrick C.;
Wakim, Linda M.

Publication type:

Article

Single-cell RNA-seq and computational analysis using temporal mixture modeling resolves TH1/TFH fate bifurcation in malaria.

Published in:

Science Immunology, 2017, v. 2, n. 9, p. 1, doi. 10.1126/sciimmunol.aal2192

By:

Lönnberg, Tapio;
Svensson, Valentine;
James, Kylie R.;
Fernandez-Ruiz, Daniel;
Sebina, Ismail;
Montandon, Ruddy;
Soon, Megan S. F.;
Fogg, Lily G.;
Nair, Arya Sheela;
Liligeto, Urijah N.;
Stubbington, Michael J. T.;
Lam-Ha Ly;
Bagger, Frederik Otzen;
Zwiessele, Max;
Lawrence, Neil D.;
Souza-Fonseca-Guimaraes, Fernando;
Bunn, Patrick T.;
Engwerda, Christian R.;
Heath, William R.;
Billker, Oliver

Publication type:

Article

The liver contains distinct interconnected networks of CX3CR1+ macrophages, XCR1+ type 1 and CD301a+ type 2 conventional dendritic cells embedded within portal tracts.

Published in:

Immunology & Cell Biology, 2022, v. 100, n. 6, p. 394, doi. 10.1111/imcb.12559

By:

English, Kieran;
Tan, Sioh Yang;
Kwan, Rain;
Holz, Lauren E;
Sierro, Frederic;
McGuffog, Claire;
Kaisho, Tsuneyasu;
Heath, William R;
MacDonald, Kelli PA;
McCaughan, Geoffrey W;
Bowen, David G;
Bertolino, Patrick

Publication type:

Article

Rapid recruitment and activation of CD8+ T cells after herpes simplex virus type 1 skin infection.

Published in:

Immunology & Cell Biology, 2011, v. 89, n. 1, p. 143, doi. 10.1038/icb.2010.66

By:

Stock, Angus T;
Jones, Claerwen M;
Heath, William R;
Carbone, Francis R

Publication type:

Article

Equivalent stimulation of naive and memory CD8 T cells by DNA vaccination: a dendritic cell-dependent process.

Published in:

Immunology & Cell Biology, 2009, v. 87, n. 3, p. 255, doi. 10.1038/icb.2008.105

By:

Bedoui, Sammy;
Davey, Gayle M.;
Lew, Andrew M.;
Heath, William R.

Publication type:

Article

Equivalent stimulation of naive and memory CD8 T cells by DNA vaccination: a dendritic cell‐dependent process.

Published in:

Immunology & Cell Biology, 2009, v. 87, n. 3, p. 255, doi. 10.1038/icb.2008.105

By:

Bedoui, Sammy;
Davey, Gayle M;
Lew, Andrew M;
Heath, William R

Publication type:

Article

Normal proportion and expression of maturation markers in migratory dendritic cells in the absence of germs or Toll-like receptor signaling.

Published in:

Immunology & Cell Biology, 2008, v. 86, n. 2, p. 200, doi. 10.1038/sj.icb.7100125

By:

Wilson, Nicholas S.;
Young, Louise J.;
Kupresanin, Fiona;
Naik, Shalin H.;
Vremec, David;
Heath, William R.;
Akira, Shizuo;
Shortman, Ken;
Boyle, Jeff;
Maraskovsky, Eugene;
Belz, Gabrielle T.;
Villadangos, José A.

Publication type:

Article

Too dangerous to ignore: self-tolerance and the control of ignorant autoreactive T cells.

Published in:

Immunology & Cell Biology, 2008, v. 86, n. 2, p. 146, doi. 10.1038/sj.icb.7100161

By:

Parish, Ian A.;
Heath, William R.

Publication type:

Article

Optimization of TCR transgenic T cells for in vivo tracking of immune responses.

Published in:

Immunology & Cell Biology, 2007, v. 85, n. 5, p. 394, doi. 10.1038/sj.icb.7100076

By:

Stock, Angus T.;
Mueller, Scott N.;
Kleinert, Lauren M.;
Heath, William R.;
Carbone, Francis R.;
Jones, Claerwen M.

Publication type:

Article

CTL response compensation for the loss of an immunodominant class I-restricted HSV-1 determinant.

Published in:

Immunology & Cell Biology, 2006, v. 84, n. 6, p. 543, doi. 10.1111/j.1440-1711.2006.01469.x

By:

STOCK, ANGUS T.;
JONES, CLAERWEN M.;
HEATH, WILLIAM R.;
CARBONE, FRANCIS R.

Publication type:

Article

Special Feature Helper T cells, dendritic cells and CTL Immunity.

Published in:

Immunology & Cell Biology, 2004, v. 82, n. 1, p. 84, doi. 10.1111/j.1440-1711.2004.01211.x

By:

Behrens, Georg;
Li, Ming;
Smith, Christopher M.;
Belz, Gabrielle T.;
Mintern, Justine;
Carbone, Francis R.;
Heath, William R.

Publication type:

Article

Differential location of NKT and MAIT cells within lymphoid tissue.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-07704-4

By:

Johnson, Darryl N.;
Ruan, Zheng;
Petley, Emma V.;
Devi, Sapna;
Holz, Lauren E.;
Uldrich, Adam P.;
Mak, Jeffrey Y. W.;
Hor, Jyh Liang;
Mueller, Scott N.;
McCluskey, James;
Fairlie, David P.;
Darcy, Phillip K.;
Beavis, Paul A.;
Heath, William R.;
Godfrey, Dale I.

Publication type:

Article

Type I interferon production elicits differential CD4+ T-cell responses in mice infected with Plasmodium berghei ANKA and P. chabaudi.

Published in:

International Immunology, 2022, v. 34, n. 1, p. 21, doi. 10.1093/intimm/dxab090

By:

Ntita, Mbaya;
Inoue, Shin-Ichi;
Jian, Jiun-Yu;
Bayarsaikhan, Ganchimeg;
Kimura, Kazumi;
Kimura, Daisuke;
Miyakoda, Mana;
Nozaki, Eriko;
Sakurai, Takuya;
Fernandez-Ruiz, Daniel;
Heath, William R;
Yui, Katsuyuki

Publication type:

Article

CD49d marks Th1 and Tfh-like antigen-specific CD4+ T cells during Plasmodium chabaudi infection.

Published in:

International Immunology, 2021, v. 33, n. 8, p. 409, doi. 10.1093/intimm/dxab020

By:

Jian, Jiun-Yu;
Inoue, Shin-Ichi;
Bayarsaikhan, Ganchimeg;
Miyakoda, Mana;
Kimura, Daisuke;
Kimura, Kazumi;
Nozaki, Eriko;
Sakurai, Takuya;
Fernandez-Ruiz, Daniel;
Heath, William R;
Yui, Katsuyuki

Publication type:

Article

Resident Memory T Cells and Their Role within the Liver.

Published in:

International Journal of Molecular Sciences, 2020, v. 21, n. 22, p. 8565, doi. 10.3390/ijms21228565

By:

Ghilas, Sonia;
Valencia-Hernandez, Ana-Maria;
Enders, Matthias H.;
Heath, William R.;
Fernandez-Ruiz, Daniel

Publication type:

Article

Immunology: Education and promiscuity.

Published in:

Nature, 2002, v. 420, n. 6915, p. 468, doi. 10.1038/420468a

By:

Heath, William R.;
Scott, Hamish S.

Publication type:

Article

Signalling through CD30 protects against autoimmune diabetes mediated by CD8 Tcells.

Published in:

Nature, 1999, v. 398, n. 6725, p. 341, doi. 10.1038/18692

By:

Kurts, Christian;
Carbone, Francis R.;
Krummel, Matthew F.;
Koch, Karl M.;
Miller, Jacques F. A. P.;
Heath, William R.

Publication type:

Article

Help for cytotoxic-T-cell responses is mediated by CD40 signalling.

Published in:

Nature, 1998, v. 393, n. 6684, p. 478, doi. 10.1038/30996

By:

Bennett, Sally R.M.;
Carbone, Francis R.;
Karamalis, Freda;
Flavell, Richard A.;
Miller, Jacques F. A. P.;
Heath, William R.

Publication type:

Article

Oral Administration of Antigen can Lead to the Onset of Autoimmune Disease.

Published in:

International Reviews of Immunology, 1999, v. 18, n. 3, p. 217, doi. 10.3109/08830189909043026

By:

Blanas, Effrossini;
Heath, William R.

Publication type:

Article

Peptide-induced deletion of CD8 T cells in vivo occurs via apoptosis in situ.

Published in:

International Immunology, 1997, v. 9, n. 10, p. 1601, doi. 10.1093/intimm/9.10.1601

By:

Koniaras, Christina;
McK. Bennett, Sally R.;
Carbone, Francis R.;
Heath, William R.;
Lew, Andrew M.

Publication type:

Article

Skin CD4+ memory T cells exhibit combined cluster-mediated retention and equilibration with the circulation.

Published in:

Nature Communications, 2016, v. 7, n. 5, p. 11514, doi. 10.1038/ncomms11514

By:

Collins, Nicholas;
Jiang, Xiaodong;
Zaid, Ali;
Macleod, Bethany L.;
Li, Jane;
Park, Chang Ook;
Haque, Ashraful;
Bedoui, Sammy;
Heath, William R.;
Mueller, Scott N.;
Kupper, Thomas S.;
Gebhardt, Thomas;
Carbone, Francis R.

Publication type:

Article

Distinct APC Subtypes Drive Spatially Segregated CD4+ and CD8+ T-Cell Effector Activity during Skin Infection with HSV-1.

Published in:

PLoS Pathogens, 2014, v. 10, n. 8, p. 1, doi. 10.1371/journal.ppat.1004303

By:

Macleod, Bethany L.;
Bedoui, Sammy;
Hor, Jyh Liang;
Mueller, Scott N.;
Russell, Tiffany A.;
Hollett, Natasha A.;
Heath, William R.;
Tscharke, David C.;
Brooks, Andrew G.;
Gebhardt, Thomas

Publication type:

Article

IP-10-Mediated T Cell Homing Promotes Cerebral Inflammation over Splenic Immunity to Malaria Infection.

Published in:

PLoS Pathogens, 2009, v. 5, n. 4, p. 1, doi. 10.1371/journal.ppat.1000369

By:

Nie, Catherine Q.;
Bernard, Nicholas J.;
Norman, M. Ursula;
Amante, Fiona H.;
Lundie, Rachel J.;
Crabb, Brendan S.;
Heath, William R.;
Engwerda, Christian R.;
Hickey, Michael J.;
Schofield, Louis;
Hansen, Diana S.

Publication type:

Article

Coupling and cross-presentation.

Published in:

Nature, 2005, v. 434, n. 7029, p. 27, doi. 10.1038/434027a

By:

Heath, William R.;
Carbone, Francis R.

Publication type:

Article

Immunology: Dangerous liaisons.

Published in:

Nature, 2003, v. 425, n. 6957, p. 460, doi. 10.1038/425460a

By:

Heath, William R.;
Carbone, Francis R.

Publication type:

Article

Neutrophils are dispensable in the modulation of T cell immunity against cutaneous HSV-1 infection.

Published in:

Scientific Reports, 2017, p. 41091, doi. 10.1038/srep41091

By:

Hor, Jyh Liang;
Heath, William R.;
Mueller, Scott N.

Publication type:

Article

Multiple Dendritic Cell Populations Activate CD4+ T Cells after Viral Stimulation.

Published in:

PLoS ONE, 2008, v. 3, n. 2, p. 1, doi. 10.1371/journal.pone.0001691

By:

Mount, Adele M.;
Smith, Christopher M.;
Kupresanin, Fiona;
Stoermer, Kristina;
Heath, William R.;
Belz, Gabrielle T.

Publication type:

Article

Kidney protection against autoreactive CD8+ T cells distinct from immunoprivilege and sequestration.

Published in:

Kidney International, 2001, v. 60, n. 2, p. 664, doi. 10.1046/j.1523-1755.2001.060002664.x

By:

Kurts, Christian;
Klebba, Ina;
Davey, Gayle M.;
Koch, Karl M.;
Miller, Jacques F.A.P.;
Heath, William R.;
Floege, Jürgen

Publication type:

Article