Works by He, Housheng Hansen

Results: 34

FOXA2 rewires AP-1 for transcriptional reprogramming and lineage plasticity in prostate cancer.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-49234-9

By:

Wang, Zifeng;
Townley, Scott L.;
Zhang, Songqi;
Liu, Mingyu;
Li, Muqing;
Labaf, Maryam;
Patalano, Susan;
Venkataramani, Kavita;
Siegfried, Kellee R.;
Macoska, Jill A.;
Han, Dong;
Gao, Shuai;
Risbridger, Gail P.;
Taylor, Renea A.;
Lawrence, Mitchell G.;
He, Housheng Hansen;
Selth, Luke A.;
Cai, Changmeng

Publication type:

Article

Pioneer of prostate cancer: past, present and the future of FOXA1.

Published in:

Protein & Cell, 2021, v. 12, n. 1, p. 29, doi. 10.1007/s13238-020-00786-8

By:

Teng, Mona;
Zhou, Stanley;
Cai, Changmeng;
Lupien, Mathieu;
He, Housheng Hansen

Publication type:

Article

A closer look into DNase I hypersensitivity.

Published in:

2013

By:

Housheng Hansen He;
Meyer, Clifford A.;
Long, Henry;
Liu, X. Shirley;
Brown, Myles

Publication type:

Conference Paper/Materials

Polycomb-independent activity of EZH2 in castration resistant prostate cancer.

Published in:

2013

By:

Kexin Xu;
Wu, Zhenhua Jeremy;
Groner, Anna C.;
Housheng Hansen He;
Changmeng Cai;
Stack, Edward C.;
Loda, Massimo;
Tao Liu;
Morrissey, Colm;
Vessella, Robert L.;
Kantoff, Philip W.;
Balk, Steven P.;
Liu, X. Shirley;
Brown, Myles

Publication type:

Conference Paper/Materials

MEDIPIPE: an automated and comprehensive pipeline for cfMeDIP-seq data quality control and analysis.

Published in:

Bioinformatics, 2023, v. 39, n. 7, p. 1, doi. 10.1093/bioinformatics/btad423

By:

Zeng, Yong;
Ye, Wenbin;
Stutheit-Zhao, Eric Y;
Han, Ming;
Bratman, Scott V;
Pugh, Trevor J;
He, Housheng Hansen

Publication type:

Article

Androgen receptor and MYC equilibration centralizes on developmental super-enhancer.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-27077-y

By:

Guo, Haiyang;
Wu, Yiming;
Nouri, Mannan;
Spisak, Sandor;
Russo, Joshua W.;
Sowalsky, Adam G.;
Pomerantz, Mark M.;
Wei, Zhao;
Korthauer, Keegan;
Seo, Ji-Heui;
Wang, Liyang;
Arai, Seiji;
Freedman, Matthew L.;
He, Housheng Hansen;
Chen, Shaoyong;
Balk, Steven P.

Publication type:

Article

Somatic driver mutation prevalence in 1844 prostate cancers identifies ZNRF3 loss as a predictor of metastatic relapse.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26489-0

By:

Fraser, Michael;
Livingstone, Julie;
Wrana, Jeffrey L.;
Finelli, Antonio;
He, Housheng Hansen;
van der Kwast, Theodorus;
Zlotta, Alexandre R.;
Bristow, Robert G.;
Boutros, Paul C.

Publication type:

Article

SPOP mutation induces DNA methylation via stabilizing GLP/G9a.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25951-3

By:

Zhang, Jianong;
Gao, Kun;
Xie, Hongyan;
Wang, Dejie;
Zhang, Pingzhao;
Wei, Ting;
Yan, Yuqian;
Pan, Yunqian;
Ye, Wenbin;
Chen, Huifen;
Shi, Qing;
Li, Yao;
Zhao, Shi-min;
Hou, Xiaonan;
Weroha, Saravut J.;
Wang, Yuzhuo;
Zhang, Jun;
Karnes, R. Jeffrey;
He, Housheng Hansen;
Wang, Liguo

Publication type:

Article

Nucleosome dynamics define transcriptional enhancers.

Published in:

Nature Genetics, 2010, v. 42, n. 4, p. 343, doi. 10.1038/ng.545

By:

Housheng Hansen He;
Meyer, Clifford A.;
Hyunjin Shin;
Bailey, Shannon T.;
Gang Wei;
Qianben Wang;
Yong Zhang;
Kexin Xu;
Min Ni;
Lupien, Mathieu;
Mieczkowski, Piotr;
Lieb, Jason D.;
Zhao, Keji;
Brown, Myles;
X. Shirley Liu

Publication type:

Article

SOX9 drives WNT pathway activation in prostate cancer.

Published in:

Journal of Clinical Investigation, 2016, v. 126, n. 5, p. 1745, doi. 10.1172/JCI78815

By:

Fen Ma;
Huihui Ye;
Housheng Hansen He;
Gerrin, Sean J.;
Sen Chen;
Tanenbaum, Benjamin A.;
Changmeng Cai;
Sowalsky, Adam G.;
Lingfeng He;
Hongyun Wang;
Balk, Steven P.;
Xin Yuan

Publication type:

Article

ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer.

Published in:

Journal of Clinical Investigation, 2013, v. 123, n. 3, p. 1109, doi. 10.1172/JCI66666

By:

Changmeng Cai;
Hongyun Wang;
Housheng Hansen He;
Sen Chen;
Lingfeng He;
Fen Ma;
Mucci, Lorelei;
Qianben Wang;
Fiore, Christopher;
Sowalsky, Adam G.;
Loda, Massimo;
Liu, X. Shirley;
Brown, Myles;
Balk, Steven P.;
Xin Yuan

Publication type:

Article

HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.59654

By:

Ho, Jessica S. Y.;
Tullio, Federico Di;
Schwarz, Megan;
Low, Diana;
Incarnato, Danny;
Gay, Florence;
Tabaglio, Tommaso;
JingXian Zhang;
Wollmann, Heike;
Chen, Leilei;
An, Omer;
Man Chan, Tim Hon;
Hickman, Alexander Hall;
Zheng, Simin;
Roudko, Vladimir;
Chen, Sujun;
Karz, Alcida;
Ahmed, Musaddeque;
He, Housheng Hansen;
Greenbaum, Benjamin D.

Publication type:

Article

The Basis and Promise of Programmable RNA Editing and Modification.

Published in:

Frontiers in Genetics, 2022, v. 13, p. 1, doi. 10.3389/fgene.2022.834413

By:

Lo, Nicholas;
Xu, Xin;
Soares, Fraser;
He, Housheng Hansen

Publication type:

Article

MYC reshapes CTCF-mediated chromatin architecture in prostate cancer.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-37544-3

By:

Wei, Zhao;
Wang, Song;
Xu, Yaning;
Wang, Wenzheng;
Soares, Fraser;
Ahmed, Musaddeque;
Su, Ping;
Wang, Tingting;
Orouji, Elias;
Xu, Xin;
Zeng, Yong;
Chen, Sujun;
Liu, Xiaoyu;
Jia, Tianwei;
Liu, Zhaojian;
Du, Lutao;
Wang, Yunshan;
Chen, Shaoyong;
Wang, Chuanxin;
He, Housheng Hansen

Publication type:

Article

Allogeneic DNT cell therapy synergizes with T cells to promote anti-leukemic activities while suppressing GvHD.

Published in:

Journal of Experimental & Clinical Cancer Research (17569966), 2025, v. 44, n. 1, p. 1, doi. 10.1186/s13046-024-03247-w

By:

Lee, Jongbok;
Kang, Hyeonjeong;
Chen, Branson;
Na, Yoosu;
Khatri, Ismat;
Soares, Fraser;
He, Housheng Hansen;
Law, Arjun D.;
Pan, Tianzhong;
Gerbitz, Armin;
Zhu, Xiaoyu;
Minden, Mark D.;
Zhang, Li

Publication type:

Article

Variant Set Enrichment: an R package to identify disease-associated functional genomic regions.

Published in:

BioData Mining, 2017, v. 10, p. 1, doi. 10.1186/s13040-017-0129-5

By:

Ahmed, Musaddeque;
Sallari, Richard C.;
Guo, Haiyang;
Moore, Jason H.;
Housheng Hansen He;
Lupien, Mathieu

Publication type:

Article

K48-linked KLF4 ubiquitination by E3 ligase Mule controls T-cell proliferation and cell cycle progression.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 14003, doi. 10.1038/ncomms14003

By:

Hao, Zhenyue;
Sheng, Yi;
Duncan, Gordon S.;
Li, Wanda Y.;
Dominguez, Carmen;
Sylvester, Jennifer;
Su, Yu-Wen;
Lin, Gloria H.Y.;
Snow, Bryan E.;
Brenner, Dirk;
You-Ten, Annick;
Haight, Jillian;
Inoue, Satoshi;
Wakeham, Andrew;
Elford, Alisha;
Hamilton, Sara;
Liang, Yi;
Zúñiga-Pflücker, Juan C.;
He, Housheng Hansen;
Ohashi, Pamela S.

Publication type:

Article

High-dimensional genomic data bias correction and data integration using MANCIE.

Published in:

Nature Communications, 2016, v. 7, n. 4, p. 11305, doi. 10.1038/ncomms11305

By:

Zang, Chongzhi;
Wang, Tao;
Deng, Ke;
Li, Bo;
Hu, Sheng'en;
Qin, Qian;
Xiao, Tengfei;
Zhang, Shihua;
Meyer, Clifford A.;
He, Housheng Hansen;
Brown, Myles;
Liu, Jun S.;
Xie, Yang;
Liu, X. Shirley

Publication type:

Article

Refined RIP-seq protocol for epitranscriptome analysis with low input materials.

Published in:

PLoS Biology, 2018, v. 16, n. 9, p. 1, doi. 10.1371/journal.pbio.2006092

By:

Zeng, Yong;
Wang, Shiyan;
Soares, Fraser;
Ahmed, Musadeqque;
Guo, Haiyang;
Wang, Miranda;
Hua, Junjie Tony;
He, Housheng Hansen;
Guan, Jiansheng;
Moran, Michael F.;
Tsao, Ming Sound;
Gao, Shanshan

Publication type:

Article

Hepatic fibroblast growth factor 21 is required for curcumin or resveratrol in exerting their metabolic beneficial effect in male mice.

Published in:

Nutrition & Diabetes, 2025, v. 15, n. 1, p. 1, doi. 10.1038/s41387-025-00363-0

By:

Feng, Jia Nuo;
Shao, Weijuan;
Yang, Lin;
Pang, Juan;
Ling, Wenhua;
Liu, Dinghui;
Wheeler, Michael B.;
He, Housheng Hansen;
Jin, Tianru

Publication type:

Article

Excessive transcription-replication conflicts are a vulnerability of BRCA1-mutant cancers.

Published in:

Nucleic Acids Research, 2023, v. 51, n. 9, p. 4341, doi. 10.1093/nar/gkad172

By:

Patel, Parasvi S;
Algouneh, Arash;
Krishnan, Rehna;
Reynolds, John J;
Nixon, Kevin C J;
Hao, Jun;
Lee, Jihoon;
Feng, Yue;
Fozil, Chehronai;
Stanic, Mia;
Yerlici, Talya;
Su, Peiran;
Soares, Fraser;
Liedtke, Elisabeth;
Prive, Gil;
Baider, Gary D;
Pujana, Miquel Angel;
Mekhail, Karim;
He, Housheng Hansen;
Hakem, Anne

Publication type:

Article

Refined DNase-seq protocol and data analysis reveals intrinsic bias in transcription factor footprint identification.

Published in:

Nature Methods, 2014, v. 11, n. 1, p. 73, doi. 10.1038/nmeth.2762

By:

He, Housheng Hansen;
Meyer, Clifford A;
Hu, Sheng'en Shawn;
Chen, Mei-Wei;
Zang, Chongzhi;
Liu, Yin;
Rao, Prakash K;
Fei, Teng;
Xu, Han;
Long, Henry;
Liu, X Shirley;
Brown, Myles

Publication type:

Article

Systematic evaluation of factors influencing ChIP-seq fidelity.

Published in:

Nature Methods, 2012, v. 9, n. 6, p. 609, doi. 10.1038/nmeth.1985

By:

Chen, Yiwen;
Negre, Nicolas;
Li, Qunhua;
Mieczkowska, Joanna O;
Slattery, Matthew;
Liu, Tao;
Zhang, Yong;
Kim, Tae-Kyung;
He, Housheng Hansen;
Zieba, Jennifer;
Ruan, Yijun;
Bickel, Peter J;
Myers, Richard M;
Wold, Barbara J;
White, Kevin P;
Lieb, Jason D;
Liu, X Shirley

Publication type:

Article

Early-life programming of mesenteric lymph node stromal cell identity by the lymphotoxin pathway regulates adult mucosal immunity.

Published in:

Science Immunology, 2019, v. 4, n. 42, p. 1, doi. 10.1126/sciimmunol.aax1027

By:

Li, Conglei;
Lam, Evelyn;
Perez-Shibayama, Christian;
Ward, Lesley A.;
Zhang, Jianbo;
Lee, Dennis;
Nguyen, Albert;
Ahmed, Musaddeque;
Brownlie, Emma;
Korneev, Kirill V.;
Rojas, Olga;
Sun, Tian;
Navarre, William;
He, Housheng Hansen;
Shan Liao;
Martin, Alberto;
Ludewig, Burkhard;
Gommerman, Jennifer L.

Publication type:

Article

m6Am Methyltransferase PCIF1 Promotes LPP3 Mediated Phosphatidic Acid Metabolism and Renal Cell Carcinoma Progression.

Published in:

Advanced Science, 2024, v. 11, n. 46, p. 1, doi. 10.1002/advs.202404033

By:

Luo, Wenqin;
Xu, Zhehao;
Li, Fan;
Ding, Lifeng;
Wang, Ruyue;
Lin, Yudong;
Mao, Xudong;
Chen, Xianjiong;
Li, Yang;
Lu, Zeyi;
Xie, Haiyun;
Wang, Huan;
Zhu, Ziwei;
Lu, Yi;
Guo, Luying;
Yu, Xiaojing;
Xia, Liqun;
He, Housheng Hansen;
Li, Gonghui

Publication type:

Article

Human Helicase DDX: Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation (Adv. Sci. 14/2020).

Published in:

Advanced Science, 2020, v. 7, n. 14, p. 1, doi. 10.1002/advs.202070077

By:

Chen, Zijun;
Li, Zhengyang;
Hu, Xiaojian;
Xie, Feiyan;
Kuang, Siyun;
Zhan, Bowen;
Gao, Wenqing;
Chen, Xiangjun;
Gao, Siqi;
Li, Yang;
Wang, Yongming;
Qian, Feng;
Ding, Chen;
Gan, Jianhua;
Ji, Chaoneng;
Xu, Xue‐Wei;
Zhou, Zheng;
Huang, Jinqing;
He, Housheng Hansen;
Li, Jixi

Publication type:

Article

Structural Basis of Human Helicase DDX21 in RNA Binding, Unwinding, and Antiviral Signal Activation.

Published in:

Advanced Science, 2020, v. 7, n. 14, p. 1, doi. 10.1002/advs.202000532

By:

Chen, Zijun;
Li, Zhengyang;
Hu, Xiaojian;
Xie, Feiyan;
Kuang, Siyun;
Zhan, Bowen;
Gao, Wenqing;
Chen, Xiangjun;
Gao, Siqi;
Li, Yang;
Wang, Yongming;
Qian, Feng;
Ding, Chen;
Gan, Jianhua;
Ji, Chaoneng;
Xu, Xue‐Wei;
Zhou, Zheng;
Huang, Jinqing;
He, Housheng Hansen;
Li, Jixi

Publication type:

Article

Haploinsufficiency of RREB1 causes a Noonan-like RASopathy via epigenetic reprogramming of RAS-MAPK pathway genes.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-18483-9

By:

Kent, Oliver A.;
Saha, Manipa;
Coyaud, Etienne;
Burston, Helen E.;
Law, Napoleon;
Dadson, Keith;
Chen, Sujun;
Laurent, Estelle M.;
St-Germain, Jonathan;
Sun, Ren X.;
Matsumoto, Yoshinori;
Cowen, Justin;
Montgomery-Song, Aaryn;
Brown, Kevin R.;
Ishak, Charles;
Rose, Jose La;
De Carvalho, Daniel D.;
He, Housheng Hansen;
Raught, Brian;
Billia, Filio

Publication type:

Article

Digital Quantification of Gene Expression in Sequential Breast Cancer Biopsies Reveals Activation of an Immune Response

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0064225

By:

Jeselsohn, Rinath M.;
Werner, Lillian;
Regan, Meredith M.;
Fatima, Aquila;
Gilmore, Lauren;
Collins, Laura C.;
Beck, Andrew H.;
Bailey, Shannon T.;
He, Housheng Hansen;
Buchwalter, Gilles;
Brown, Myles;
Iglehart, J. Dirk;
Richardson, Andrea;
Come, Steven E.

Publication type:

Article

GlcNAcylation of histone H2B facilitates its monoubiquitination.

Published in:

Nature, 2011, v. 480, n. 7378, p. 557, doi. 10.1038/nature10656

By:

Fujiki, Ryoji;
Hashiba, Waka;
Sekine, Hiroki;
Yokoyama, Atsushi;
Chikanishi, Toshihiro;
Ito, Saya;
Imai, Yuuki;
Kim, Jaehoon;
He, Housheng Hansen;
Igarashi, Katsuhide;
Kanno, Jun;
Ohtake, Fumiaki;
Kitagawa, Hirochika;
Roeder, Robert G.;
Brown, Myles;
Kato, Shigeaki

Publication type:

Article

Genome-wide studies in prostate cancer poised liquid biopsy as a molecular discovery tool.

Published in:

Frontiers in Oncology, 2023, p. 1, doi. 10.3389/fonc.2023.1185013

By:

Lo, Nicholas;
Housheng Hansen He;
Sujun Chen

Publication type:

Article

N<sup>6</sup>-methyladenosine mRNA marking promotes selective translation of regulons required for human erythropoiesis.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-12518-6

By:

Kuppers, Daniel A.;
Arora, Sonali;
Lim, Yiting;
Lim, Andrea R.;
Carter, Lucas M.;
Corrin, Philip D.;
Plaisier, Christopher L.;
Basom, Ryan;
Delrow, Jeffrey J.;
Wang, Shiyan;
Hansen He, Housheng;
Torok-Storb, Beverly;
Hsieh, Andrew C.;
Paddison, Patrick J.

Publication type:

Article

DNA methylation modulated genetic variant effect on gene transcriptional regulation.

Published in:

Genome Biology, 2023, v. 24, n. 1, p. 1, doi. 10.1186/s13059-023-03130-5

By:

Zeng, Yong;
Jain, Rahi;
Lam, Magnus;
Ahmed, Musaddeque;
Guo, Haiyang;
Xu, Wenjie;
Zhong, Yuan;
Wei, Gong-Hong;
Xu, Wei;
He, Housheng Hansen

Publication type:

Article

Oral pimonidazole unveils clinicopathologic and epigenetic features of hypoxic tumour aggressiveness in localized prostate cancer.

Published in:

BMC Cancer, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12885-024-12505-1

By:

Ci, Xinpei;
Chen, Sujun;
Zhu, Rui;
Zarif, Mojgan;
Jain, Rahi;
Guo, Wangyuan;
Ramotar, Matthew;
Gong, Linsey;
Xu, Wenjie;
Singh, Olivia;
Mansouri, Sheila;
Zadeh, Gelareh;
Wei, Gong-Hong;
Xu, Wei;
Bristow, Robert;
Berlin, Alejandro;
Koritzinsky, Marianne;
van der Kwast, Theodorus;
He, Housheng Hansen

Publication type:

Article