Works by Hazawa, Masaharu

Results: 40

Spatiotemporal dynamics of protamine–DNA condensation revealed by high-speed atomic force microscopy Open Access.

Published in:

Nucleic Acids Research, 2025, v. 53, n. 6, p. 1, doi. 10.1093/nar/gkaf152

By:

Nishide, Goro;
Lim, Keesiang;
Kobayashi, Akiko;
Qiu, Yujia;
Hazawa, Masaharu;
Ando, Toshio;
Okada, Yuki;
Wong, Richard W

Publication type:

Article

Spatiotemporal tracking of small extracellular vesicle nanotopology in response to physicochemical stresses revealed by HS‐AFM.

Published in:

Journal of Extracellular Vesicles, 2022, v. 11, n. 11, p. 1, doi. 10.1002/jev2.12275

By:

Sajidah, Elma Sakinatus;
Lim, Keesiang;
Yamano, Tomoyoshi;
Nishide, Goro;
Qiu, Yujia;
Yoshida, Takeshi;
Wang, Hanbo;
Kobayashi, Akiko;
Hazawa, Masaharu;
Dewi, Firli R. P.;
Hanayama, Rikinari;
Ando, Toshio;
Wong, Richard W.

Publication type:

Article

Millisecond dynamic of SARS‐CoV‐2 spike and its interaction with ACE2 receptor and small extracellular vesicles.

Published in:

Journal of Extracellular Vesicles, 2021, v. 10, n. 14, p. 1, doi. 10.1002/jev2.12170

By:

Lim, Keesiang;
Nishide, Goro;
Yoshida, Takeshi;
Watanabe‐Nakayama, Takahiro;
Kobayashi, Akiko;
Hazawa, Masaharu;
Hanayama, Rikinari;
Ando, Toshio;
Wong, Richard W.

Publication type:

Article

Reciprocal inhibition between TP63 and STAT1 regulates anti-tumor immune response through interferon-γ signaling in squamous cancer.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-46785-9

By:

Jiang, Yuan;
Zheng, Yueyuan;
Zhang, Yuan-Wei;
Kong, Shuai;
Dong, Jinxiu;
Wang, Fei;
Ziman, Benjamin;
Gery, Sigal;
Hao, Jia-Jie;
Zhou, Dan;
Zhou, Jianian;
Ho, Allen S.;
Sinha, Uttam K.;
Chen, Jian;
Zhang, Shuo;
Yin, Chuntong;
Wei, Dan-Dan;
Hazawa, Masaharu;
Pan, Huaguang;
Lu, Zhihao

Publication type:

Article

Karyopherin-β1 Regulates Radioresistance and Radiation-Increased Programmed Death-Ligand 1 Expression in Human Head and Neck Squamous Cell Carcinoma Cell Lines.

Published in:

Cancers, 2020, v. 12, n. 4, p. 908, doi. 10.3390/cancers12040908

By:

Hazawa, Masaharu;
Yoshino, Hironori;
Nakagawa, Yuta;
Shimizume, Reina;
Nitta, Keisuke;
Sato, Yoshiaki;
Sato, Mariko;
Wong, Richard W.;
Kashiwakura, Ikuo

Publication type:

Article

Novel function of HATs and HDACs in homologous recombination through acetylation of human RAD52 at double-strand break sites.

Published in:

PLoS Genetics, 2018, v. 14, n. 3, p. 1, doi. 10.1371/journal.pgen.1007277

By:

Yasuda, Takeshi;
Kagawa, Wataru;
Ogi, Tomoo;
Kato, Takamitsu A.;
Suzuki, Takehiro;
Dohmae, Naoshi;
Takizawa, Kazuya;
Nakazawa, Yuka;
Genet, Matthew D.;
Saotome, Mika;
Hama, Michio;
Konishi, Teruaki;
Nakajima, Nakako Izumi;
Hazawa, Masaharu;
Tomita, Masanori;
Koike, Manabu;
Noshiro, Katsuko;
Tomiyama, Kenichi;
Obara, Chizuka;
Gotoh, Takaya

Publication type:

Article

Optimization of Zwitterionic Polymers for Cell Cryopreservation.

Published in:

Macromolecular Bioscience, 2024, v. 24, n. 7, p. 1, doi. 10.1002/mabi.202470016

By:

Kato, Yui;
Uto, Takuya;
Ishizaki, Takeru;
Tanaka, Daisuke;
Ishibashi, Kojiro;
Matsuda, Yuya;
Onoda, Issei;
Kobayashi, Akiko;
Hazawa, Masaharu;
Wong, Richard W.;
Takahashi, Kenji;
Hirata, Eishu;
Kuroda, Kosuke

Publication type:

Article

Optimization of Zwitterionic Polymers for Cell Cryopreservation.

Published in:

Macromolecular Bioscience, 2024, v. 24, n. 7, p. 1, doi. 10.1002/mabi.202300499

By:

Kato, Yui;
Uto, Takuya;
Ishizaki, Takeru;
Tanaka, Daisuke;
Ishibashi, Kojiro;
Matsuda, Yuya;
Onoda, Issei;
Kobayashi, Akiko;
Hazawa, Masaharu;
Wong, Richard W.;
Takahashi, Kenji;
Hirata, Eishu;
Kuroda, Kosuke

Publication type:

Article

Caspase-independent apoptosis induction of quorum-sensing autoinducer analogs against chronic myeloid leukemia K562.

Published in:

Investigational New Drugs, 2012, v. 30, n. 3, p. 862, doi. 10.1007/s10637-010-9623-z

By:

Hazawa, Masaharu;
Kudo, Michiko;
Iwata, Toshihiro;
Saito, Kazuki;
Takahashi, Kenji;
Igarashi, Jun;
Suga, Hiroaki;
Kashiwakura, Ikuo

Publication type:

Article

Functional properties of synthetic N-acyl-L-homoserine lactone analogs of quorum-sensing gram-negative bacteria on the growth of human oral squamous carcinoma cells.

Published in:

Investigational New Drugs, 2012, v. 30, n. 1, p. 157, doi. 10.1007/s10637-010-9544-x

By:

Chai, Hongbo;
Hazawa, Masaharu;
Shirai, Naoko;
Igarashi, Jun;
Takahashi, Kenji;
Hosokawa, Yoichiro;
Suga, Hiroaki;
Kashiwakura, Ikuo

Publication type:

Article

Liquid crystal-related compound-induced cell growth suppression and apoptosis in the chronic myelogenous leukemia K562 cell line.

Published in:

Investigational New Drugs, 2011, v. 29, n. 5, p. 827, doi. 10.1007/s10637-010-9430-6

By:

Fukushi, Yukako;
Hazawa, Masaharu;
Takahashi, Kenji;
Yoshizawa, Atsushi;
Kashiwakura, Ikuo

Publication type:

Article

Suppressive effects of liquid crystal compounds on the growth of the A549 human lung cancer cell line.

Published in:

Investigational New Drugs, 2011, v. 29, n. 4, p. 659, doi. 10.1007/s10637-010-9411-9

By:

Takahashi, Yuuka;
Hazawa, Masaharu;
Takahashi, Kenji;
Nishizawa, Ayumi;
Yoshizawa, Atsushi;
Kashiwakura, Ikuo

Publication type:

Article

Structure-activity relationships between the Aconitum C20-diterpenoid alkaloid derivatives and the growth suppressive activities of Non-Hodgkin's lymphoma Raji cells and human hematopoietic stem/progenitor cells.

Published in:

2011

By:

Hazawa, Masaharu;
Takahashi, Kenji;
Wada, Koji;
Mori, Takao;
Kawahara, Norio;
Kashiwakura, Ikua

Publication type:

Journal Article

Structure-activity relationships between the Aconitum C-diterpenoid alkaloid derivatives and the growth suppressive activities of Non-Hodgkin's lymphoma Raji cells and human hematopoietic stem/progenitor cells.

Published in:

Investigational New Drugs, 2011, v. 29, n. 1, p. 1, doi. 10.1007/s10637-009-9327-4

By:

Hazawa, Masaharu;
Takahashi, Kenji;
Wada, Koji;
Mori, Takao;
Kawahara, Norio;
Kashiwakura, Ikuo

Publication type:

Article

Suppressive effects of novel derivatives prepared from Aconitum alkaloids on tumor growth.

Published in:

Investigational New Drugs, 2009, v. 27, n. 2, p. 111, doi. 10.1007/s10637-008-9141-4

By:

Hazawa, Masaharu;
Wada, Koji;
Takahashi, Kenji;
Mori, Takao;
Kawahara, Norio;
Kashiwakura, Ikuo

Publication type:

Article

Co-activation of super-enhancer-driven CCAT1 by TP63 and SOX2 promotes squamous cancer progression.

Published in:

Nature Communications, 2018, p. 1, doi. 10.1038/s41467-018-06081-9

By:

Yuan Jiang;
Yan-Yi Jiang;
Jian-Jun Xie;
Mayakonda, Anand;
Hazawa, Masaharu;
Li Chen;
Jin-Fen Xiao;
Chun-Quan Li;
Mo-Li Huang;
Ling-Wen Ding;
Qiao-Yang Sun;
Liang Xu;
Kanojia, Deepika;
Maya Jeitany;
Jian-Wen Deng;
Lian-Di Liao;
Soukiasian, Harmik J.;
Berman, Benjamin P.;
Jia-Jie Hao;
Li-Yan Xu

Publication type:

Article

Maternal and Neonatal Factors Associated with the High Yield of Mononuclear Low-Density/CD34<sup>+</sup> Cells from Placental/Umbilical Cord Blood.

Published in:

Tohoku Journal of Experimental Medicine, 2008, v. 215, n. 1, p. 23, doi. 10.1620/tjem.215.23

By:

Omori, Atsuko;
Takahashi, Kenji;
Hazawa, Masaharu;
Misaki, Naoko;
Ohba, Hisateru;
Manabe, Mami;
Sato, Haruo;
Kudo, Kaori;
Takahashi, Tsuneo A.;
Kashiwakura, Ikuo

Publication type:

Article

ROCK‐dependent phosphorylation of NUP62 regulates p63 nuclear transport and squamous cell carcinoma proliferation.

Published in:

EMBO Reports, 2018, v. 19, n. 1, p. 73, doi. 10.15252/embr.201744523

By:

Hazawa, Masaharu;
Lin, De‐Chen;
Kobayashi, Akiko;
Jiang, Yan‐Yi;
Xu, Liang;
Dewi, Firli Rahmah Primula;
Mohamed, Mahmoud Shaaban;
Hartono;
Nakada, Mitsutoshi;
Meguro‐Horike, Makiko;
Horike, Shin‐ichi;
Koeffler, H. Phillip;
Wong, Richard W.

Publication type:

Article

Vitronectin improves cell survival after radiation injury in human umbilical vein endothelial cells

Published in:

FEBS Open Bio, 2012, v. 2, p. 334, doi. 10.1016/j.fob.2012.10.002

By:

Hazawa, Masaharu;
Yasuda, Takeshi;
Noshiro, Katsuko;
Saotome-Nakamura, Ai;
Fukuzaki, Tomoko;
Michikawa, Yuichi;
Gotoh, Takaya;
Tajima, Katsushi

Publication type:

Article

Vitronectin improves cell survival after radiation injury in human umbilical vein endothelial cells.

Published in:

FEBS Open Bio, 2012, v. 2, n. 1, p. 334, doi. 10.1016/j.fob.2012.10.002

By:

Hazawa, Masaharu;
Yasuda, Takeshi;
Noshiro, Katsuko;
Saotome-Nakamura, Ai;
Fukuzaki, Tomoko;
Michikawa, Yuichi;
Gotoh, Takaya;
Tajima, Katsushi

Publication type:

Article

Structure-activity relationships and the cytotoxic effects of novel diterpenoid alkaloid derivatives against A549 human lung carcinoma cells.

Published in:

Journal of Natural Medicines, 2011, v. 65, n. 1, p. 43, doi. 10.1007/s11418-010-0452-3

By:

Wada, Koji;
Hazawa, Masaharu;
Takahashi, Kenji;
Mori, Takao;
Kawahara, Norio;
Kashiwakura, Ikuo

Publication type:

Article

Biological Activity of Some Cyanobiphenyl Derivatives.

Published in:

Chemistry Letters, 2009, v. 38, n. 6, p. 8, doi. 10.1246/cl.2009.530

By:

Yoshizawa, Atsushi;
Takahashi, Yuuka;
Nishizawa, Ayumi;
Takeuchi, Kazuhito;
Sagisaka, Masanobu;
Takahashi, Kenji;
Hazawa, Masaharu;
Kashiwakura, Ikuo

Publication type:

Article

Liquid Crystallinity and Biological Activity of a Novel Amphiphilic Compound.

Published in:

Chemistry Letters, 2009, v. 38, n. 4, p. 1, doi. 10.1246/cl.2009.310

By:

Yoshizawa, Atsushi;
Takahashi, Yuuka;
Terasawa, Rie;
Chiba, Shota;
Takahashi, Kenji;
Hazawa, Masaharu;
Kashiwakura, Ikuo

Publication type:

Article

Aconitum C<sub>20</sub>-diterpenoid Alkaloid Derivatives Regulate the Growth and Differentiation of Cord Blood Derived Human Hematopoietic Stem/Progenitor Cells.

Published in:

Phytotherapy Research, 2012, v. 26, n. 8, p. 1262, doi. 10.1002/ptr.3718

By:

Hazawa, Masaharu;
Wada, Koji;
Kashiwakura, Ikuo

Publication type:

Article

Nanoscopic Profiling of Small Extracellular Vesicles via High‐Speed Atomic Force Microscopy (HS‐AFM) Videography.

Published in:

Journal of Extracellular Vesicles, 2025, v. 14, n. 4, p. 1, doi. 10.1002/jev2.70050

By:

Sandira, Muhammad Isman;
Lim, Keesiang;
Yoshida, Takeshi;
Sajidah, Elma Sakinatus;
Narimatsu, Shinnosuke;
Imakawa, Reon;
Yoshimura, Kota;
Nishide, Goro;
Qiu, Yujia;
Taoka, Azuma;
Hazawa, Masaharu;
Ando, Toshio;
Hanayama, Rikinari;
Wong, Richard W.

Publication type:

Article

Nucleoporin Nup58 localizes to centrosomes and mid-bodies during mitosis.

Published in:

Cell Division, 2019, v. 14, n. 1, p. N.PAG, doi. 10.1186/s13008-019-0050-z

By:

Hartono;
Hazawa, Masaharu;
Lim, Kee Siang;
Dewi, Firli R. P.;
Kobayashi, Akiko;
Wong, Richard W.

Publication type:

Article

Unlocking the Gateway: The Spatio-Temporal Dynamics of the p53 Family Driven by the Nuclear Pores and Its Implication for the Therapeutic Approach in Cancer.

Published in:

International Journal of Molecular Sciences, 2024, v. 25, n. 13, p. 7465, doi. 10.3390/ijms25137465

By:

Ikliptikawati, Dini Kurnia;
Makiyama, Kei;
Hazawa, Masaharu;
Wong, Richard W.

Publication type:

Article

Cell-compatible isotonic freezing media enabled by thermo-responsive osmolyte-adsorption/exclusion polymer matrices.

Published in:

Communications Chemistry, 2023, v. 6, n. 1, p. 1, doi. 10.1038/s42004-023-01061-7

By:

Kato, Yui;
Matsuda, Yuya;
Uto, Takuya;
Tanaka, Daisuke;
Ishibashi, Kojiro;
Ishizaki, Takeru;
Ohta, Akio;
Kobayashi, Akiko;
Hazawa, Masaharu;
Wong, Richard W.;
Ninomiya, Kazuaki;
Takahashi, Kenji;
Hirata, Eishu;
Kuroda, Kosuke

Publication type:

Article

Activation of bivalent factor DLX5 cooperates with master regulator TP63 to promote squamous cell carcinoma.

Published in:

Nucleic Acids Research, 2021, v. 49, n. 16, p. 9246, doi. 10.1093/nar/gkab679

By:

Huang, Yongsheng;
Yang, Qian;
Zheng, Yueyuan;
Lin, Lehang;
Xu, Xin;
Xu, Xiu-E;
Silva, Tiago C;
Hazawa, Masaharu;
Peng, Li;
Cao, Haotian;
Ding, Yanbing;
Lu, Daning;
Berman, Benjamin P;
Xu, Li-Yan;
Li, En-Min;
Yin, Dong

Publication type:

Article

Sulfation of keratan sulfate proteoglycan reduces radiation-induced apoptosis in human Burkitt’s lymphoma cell lines

Published in:

FEBS Letters, 2013, v. 587, n. 2, p. 231, doi. 10.1016/j.febslet.2012.12.002

By:

Nakayama, Fumiaki;
Umeda, Sachiko;
Ichimiya, Tomomi;
Kamiyama, Shin;
Hazawa, Masaharu;
Yasuda, Takeshi;
Nishihara, Shoko;
Imai, Takashi

Publication type:

Article

Phase-separated super-enhancers confer an innate radioresistance on genomic DNA.

Published in:

Journal of Radiation Research, 2024, v. 65, n. 4, p. 482, doi. 10.1093/jrr/rrae044

By:

Matsumoto, Koki;
Ikliptikawati, Dini Kurnia;
Makiyama, Kei;
Mochizuki, Kako;
Tobita, Maho;
Kobayashi, Isao;
Voon, Dominic Chih-Cheng;
Lim, Keesiang;
Ogawa, Kazuma;
Kashiwakura, Ikuo;
Suzuki, Hiroshi I;
Yoshino, Hironori;
Wong, Richard W;
Hazawa, Masaharu

Publication type:

Article

Strategies for the Viral Exploitation of Nuclear Pore Transport Pathways.

Published in:

2025

By:

Zhang, Xin;
Lim, Keesiang;
Qiu, Yujia;
Hazawa, Masaharu;
Wong, Richard W.

Publication type:

Literature Review

Synthetic zwitterions as efficient non-permeable cryoprotectants.

Published in:

Communications Chemistry, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42004-021-00588-x

By:

Kato, Yui;
Uto, Takuya;
Tanaka, Daisuke;
Ishibashi, Kojiro;
Kobayashi, Akiko;
Hazawa, Masaharu;
Wong, Richard W.;
Ninomiya, Kazuaki;
Takahashi, Kenji;
Hirata, Eishu;
Kuroda, Kosuke

Publication type:

Article

An Efficient Method for Isolating and Purifying Nuclei from Mice Brain for Single-Molecule Imaging Using High-Speed Atomic Force Microscopy.

Published in:

Cells (2073-4409), 2024, v. 13, n. 3, p. 279, doi. 10.3390/cells13030279

By:

Qiu, Yujia;
Sajidah, Elma Sakinatus;
Kondo, Sota;
Narimatsu, Shinnosuke;
Sandira, Muhammad Isman;
Higashiguchi, Yoshiki;
Nishide, Goro;
Taoka, Azuma;
Hazawa, Masaharu;
Inaba, Yuka;
Inoue, Hiroshi;
Matsushima, Ayami;
Okada, Yuki;
Nakada, Mitsutoshi;
Ando, Toshio;
Lim, Keesiang;
Wong, Richard W.

Publication type:

Article

Discovery of a Novel Aminocyclopropenone Compound That Inhibits BRD4-Driven Nucleoporin NUP210 Expression and Attenuates Colorectal Cancer Growth.

Published in:

Cells (2073-4409), 2022, v. 11, n. 3, p. 317, doi. 10.3390/cells11030317

By:

Kondo, Hiroya;
Mishiro, Kenji;
Iwashima, Yuki;
Qiu, Yujia;
Kobayashi, Akiko;
Lim, Keesiang;
Domoto, Takahiro;
Minamoto, Toshinari;
Ogawa, Kazuma;
Kunishima, Munetaka;
Hazawa, Masaharu;
Wong, Richard W.

Publication type:

Article

Nucleoporin TPR (translocated promoter region, nuclear basket protein) upregulation alters MTOR-HSF1 trails and suppresses autophagy induction in ependymoma.

Published in:

Autophagy, 2021, v. 17, n. 4, p. 1001, doi. 10.1080/15548627.2020.1741318

By:

Dewi, Firli Rahmah Primula;
Jiapaer, Shabierjiang;
Kobayashi, Akiko;
Hazawa, Masaharu;
Ikliptikawati, Dini Kurnia;
Hartono;
Sabit, Hemragul;
Nakada, Mitsutoshi;
Wong, Richard W.

Publication type:

Article

Inhibition of Canonical Wnt Signaling Promotes Ex Vivo Maintenance and Proliferation of Hematopoietic Stem Cells in Zebrafish.

Published in:

Stem Cells, 2022, v. 40, n. 9, p. 831, doi. 10.1093/stmcls/sxac044

By:

Kimura, Koki;
Yamamori, Shiori;
Hazawa, Masaharu;
Kobayashi-Sun, Jingjing;
Kondo, Mao;
Wong, Richard W;
Kobayashi, Isao

Publication type:

Article

The genomic landscape of nasopharyngeal carcinoma.

Published in:

Nature Genetics, 2014, v. 46, n. 8, p. 866, doi. 10.1038/ng.3006

By:

Lin, De-Chen;
Meng, Xuan;
Hazawa, Masaharu;
Nagata, Yasunobu;
Varela, Ana Maria;
Xu, Liang;
Sato, Yusuke;
Liu, Li-Zhen;
Ding, Ling-Wen;
Sharma, Arjun;
Goh, Boon Cher;
Lee, Soo Chin;
Petersson, Bengt Fredrik;
Yu, Feng Gang;
Macary, Paul;
Oo, Min Zin;
Ha, Chan Soh;
Yang, Henry;
Ogawa, Seishi;
Loh, Kwok Seng

Publication type:

Article

Interplay and cooperation between SREBF1 and master transcription factors regulate lipid metabolism and tumor-promoting pathways in squamous cancer.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24656-x

By:

Li, Li-Yan;
Yang, Qian;
Jiang, Yan-Yi;
Yang, Wei;
Jiang, Yuan;
Li, Xiang;
Hazawa, Masaharu;
Zhou, Bo;
Huang, Guo-Wei;
Xu, Xiu-E;
Gery, Sigal;
Zhang, Ying;
Ding, Ling-Wen;
Ho, Allen S.;
Zumsteg, Zachary S.;
Wang, Ming-Rong;
Fullwood, Melissa J.;
Freedland, Stephen J.;
Meltzer, Stephen J.;
Xu, Li-Yan

Publication type:

Article

Differentiation and Molecular Properties of Mesenchymal Stem Cells Derived from Murine Induced Pluripotent Stem Cells Derived on Gelatin or Collagen.

Published in:

Stem Cells International, 2016, p. 1, doi. 10.1155/2016/9013089

By:

Obara, Chizuka;
Takizawa, Kazuya;
Tomiyama, Kenichi;
Hazawa, Masaharu;
Saotome-Nakamura, Ai;
Gotoh, Takaya;
Yasuda, Takeshi;
Tajima, Katsushi

Publication type:

Article