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The causal relevance of body mass index in different histological types of lung cancer: A Mendelian randomization study.
Published in:
Scientific Reports, 2016, p. 31121, doi. 10.1038/srep31121
By:
- Carreras-Torres, Robert;
- Haycock, Philip C.;
- Relton, Caroline L.;
- Martin, Richard M.;
- Smith, George Davey;
- Kraft, Peter;
- Gao, Chi;
- Tworoger, Shelley;
- Le Marchand, Loïc;
- Wilkens, Lynne R.;
- Park, Sungshim L.;
- Haiman, Christopher;
- Field, John K.;
- Davies, Michael;
- Marcus, Michael;
- Liu, Geoffrey;
- Caporaso, Neil E.;
- Christiani, David C.;
- Wei, Yongyue;
- Chen, Chu
Publication type:
Article
PhenoSpD: an integrated toolkit for phenotypic correlation estimation and multiple testing correction using GWAS summary statistics.
Published in:
GigaScience, 2018, v. 7, n. 8, p. N.PAG, doi. 10.1093/gigascience/giy090
By:
- Zheng, Jie;
- Richardson, Tom G;
- Millard, Louise A C;
- Hemani, Gibran;
- Elsworth, Benjamin L;
- Raistrick, Christopher A;
- Vilhjalmsson, Bjarni;
- Neale, Benjamin M;
- Haycock, Philip C;
- Smith, George Davey
Publication type:
Article
Identifying drug targets for neurological and psychiatric disease via genetics and the brain transcriptome.
Published in:
PLoS Genetics, 2021, v. 17, n. 1, p. 1, doi. 10.1371/journal.pgen.1009224
By:
- Baird, Denis A.;
- Liu, Jimmy Z.;
- Zheng, Jie;
- Sieberts, Solveig K.;
- Perumal, Thanneer;
- Elsworth, Benjamin;
- Richardson, Tom G.;
- Chen, Chia-Yen;
- Carrasquillo, Minerva M.;
- Allen, Mariet;
- Reddy, Joseph S.;
- De Jager, Philip L.;
- Ertekin-Taner, Nilufer;
- Mangravite, Lara M.;
- Logsdon, Ben;
- Estrada, Karol;
- Haycock, Philip C.;
- Hemani, Gibran;
- Runz, Heiko;
- Smith, George Davey
Publication type:
Article
Role of circulating polyunsaturated fatty acids on cardiovascular diseases risk: analysis using Mendelian randomization and fatty acid genetic association data from over 114,000 UK Biobank participants.
Published in:
BMC Medicine, 2022, v. 20, n. 1, p. 1, doi. 10.1186/s12916-022-02399-w
By:
- Borges, Maria Carolina;
- Haycock, Philip C.;
- Zheng, Jie;
- Hemani, Gibran;
- Holmes, Michael V.;
- Davey Smith, George;
- Hingorani, Aroon D.;
- Lawlor, Deborah A.
Publication type:
Article
Common genetic variations in telomere length genes and lung cancer: a Mendelian randomisation study and its novel application in lung tumour transcriptome.
Published in:
eLife, 2023, p. 1, doi. 10.7554/eLife.83118
By:
- Cardoso Penha, Ricardo Cortez;
- Smith-Byrne, Karl;
- Atkins, Joshua R.;
- Haycock, Philip C.;
- Kar, Siddhartha;
- Codd, Veryan;
- Samani, Nilesh J.;
- Nelson, Christopher;
- Milojevic, Maja;
- Gabriel, Aurélie A. G.;
- Amos, Christopher;
- Brennan, Paul;
- Hung, Rayjean J.;
- Kachuri, Linda;
- Mckay, James D.
Publication type:
Article
Use of Mendelian R andomization for I dentifying R isk F actors for B rain T umors.
Published in:
Frontiers in Genetics, 2018, p. N.PAG, doi. 10.3389/fgene.2018.00525
By:
- Howell, Amy Elizabeth;
- Zheng, Jie;
- Haycock, Philip C.;
- McAleenan, Alexandra;
- Relton, Caroline;
- Martin, Richard M.;
- Kurian, Kathreena M.
Publication type:
Article
Systematic Mendelian randomization framework elucidates hundreds of CpG sites which may mediate the influence of genetic variants on disease.
Published in:
Human Molecular Genetics, 2018, v. 27, n. 18, p. 3293, doi. 10.1093/hmg/ddy210
By:
- Richardson, Tom G;
- Haycock, Philip C;
- Zheng, Jie;
- Timpson, Nicholas J;
- Gaunt, Tom R;
- Smith, George Davey;
- Relton, Caroline L;
- Hemani, Gibran
Publication type:
Article
Causal relationships between body mass index, smoking and lung cancer: Univariable and multivariable Mendelian randomization.
Published in:
International Journal of Cancer, 2021, v. 148, n. 5, p. 1077, doi. 10.1002/ijc.33292
By:
- Zhou, Wen;
- Liu, Geoffrey;
- Hung, Rayjean J.;
- Haycock, Philip C.;
- Aldrich, Melinda C.;
- Andrew, Angeline S.;
- Arnold, Susanne M.;
- Bickeböller, Heike;
- Bojesen, Stig E.;
- Brennan, Paul;
- Brunnström, Hans;
- Melander, Olle;
- Caporaso, Neil E.;
- Landi, Maria Teresa;
- Chen, Chu;
- Goodman, Gary E.;
- Christiani, David C.;
- Cox, Angela;
- Field, John K.;
- Johansson, Mikael
Publication type:
Article
Exploration of a Polygenic Risk Score for Alcohol Consumption: A Longitudinal Analysis from the ALSPAC Cohort.
Published in:
PLoS ONE, 2016, v. 11, n. 11, p. 1, doi. 10.1371/journal.pone.0167360
By:
- Taylor, Michelle;
- Simpkin, Andrew J.;
- Haycock, Philip C.;
- Dudbridge, Frank;
- Zuccolo, Luisa
Publication type:
Article
Circulating inflammatory cytokines and risk of five cancers: a Mendelian randomization analysis.
Published in:
2022
By:
- Bouras, Emmanouil;
- Karhunen, Ville;
- Gill, Dipender;
- Huang, Jian;
- Haycock, Philip C;
- Gunter, Marc J;
- Johansson, Mattias;
- Brennan, Paul;
- Key, Tim;
- Lewis, Sarah J;
- Martin, Richard M;
- Murphy, Neil;
- Platz, Elizabeth A;
- Travis, Ruth;
- Yarmolinsky, James;
- Zuber, Verena;
- Martin, Paul;
- Katsoulis, Michail;
- Freisling, Heinz;
- Nøst, Therese Haugdahl
Publication type:
journal article
The influence of obesity-related factors in the etiology of renal cell carcinoma-A mendelian randomization study.
Published in:
2019
By:
- Johansson, Mattias;
- Carreras-Torres, Robert;
- Scelo, Ghislaine;
- Purdue, Mark P.;
- Mariosa, Daniela;
- Muller, David C.;
- Timpson, Nicolas J.;
- Haycock, Philip C.;
- Brown, Kevin M.;
- Wang, Zhaoming;
- Ye, Yuanqing;
- Hofmann, Jonathan N.;
- Foll, Matthieu;
- Gaborieau, Valerie;
- Machiela, Mitchell J.;
- Colli, Leandro M.;
- Li, Peng;
- Garnier, Jean-Guillaume;
- Blanche, Helene;
- Boland, Anne
Publication type:
journal article
Estimating the causal influence of body mass index on risk of Parkinson disease: A Mendelian randomisation study.
Published in:
2017
By:
- Noyce, Alastair J.;
- Kia, Demis A.;
- Hemani, Gibran;
- Nicolas, Aude;
- Price, T. Ryan;
- De Pablo-Fernandez, Eduardo;
- Haycock, Philip C.;
- Lewis, Patrick A.;
- Foltynie, Thomas;
- Davey Smith, George;
- null, null;
- Schrag, Anette;
- Lees, Andrew J.;
- Hardy, John;
- Singleton, Andrew;
- Nalls, Mike A.;
- Pearce, Neil;
- Lawlor, Debbie A.;
- Wood, Nicholas W.;
- International Parkinson Disease Genomics Consortium
Publication type:
journal article
Design and quality control of large-scale two-sample Mendelian randomization studies.
Published in:
International Journal of Epidemiology, 2023, v. 52, n. 5, p. 1498, doi. 10.1093/ije/dyad018
By:
- Haycock, Philip C;
- Borges, Maria Carolina;
- Burrows, Kimberley;
- Lemaitre, Rozenn N;
- Harrison, Sean;
- Burgess, Stephen;
- Chang, Xuling;
- Westra, Jason;
- Khankari, Nikhil K;
- Tsilidis, Kostas K;
- Gaunt, Tom;
- Hemani, Gibran;
- Zheng, Jie;
- Truong, Therese;
- O'Mara, Tracy A;
- Spurdle, Amanda B;
- Law, Matthew H;
- Slager, Susan L;
- Birmann, Brenda M;
- Hosnijeh, Fatemeh Saberi
Publication type:
Article
Trans-ethnic Mendelian-randomization study reveals causal relationships between cardiometabolic factors and chronic kidney disease.
Published in:
2021
By:
- Zheng, Jie;
- Zhang, Yuemiao;
- Rasheed, Humaira;
- Walker, Venexia;
- Sugawara, Yuka;
- Li, Jiachen;
- Leng, Yue;
- Elsworth, Benjamin;
- Wootton, Robyn E;
- Fang, Si;
- Yang, Qian;
- Burgess, Stephen;
- Haycock, Philip C;
- Borges, Maria Carolina;
- Cho, Yoonsu;
- Carnegie, Rebecca;
- Howell, Amy;
- Robinson, Jamie;
- Thomas, Laurent F;
- Brumpton, Ben Michael
Publication type:
journal article
Appraising the causal relevance of DNA methylation for risk of lung cancer.
Published in:
2019
By:
- Battram, Thomas;
- Richmond, Rebecca C;
- Baglietto, Laura;
- Haycock, Philip C;
- Perduca, Vittorio;
- Bojesen, Stig E;
- Gaunt, Tom R;
- Hemani, Gibran;
- Guida, Florence;
- Carreras-Torres, Robert;
- Hung, Rayjean;
- Amos, Christopher I;
- Freeman, Joshua R;
- Sandanger, Torkjel M;
- Nøst, Therese H;
- Nordestgaard, Børge G;
- Teschendorff, Andrew E;
- Polidoro, Silvia;
- Vineis, Paolo;
- Severi, Gianluca
Publication type:
journal article
Circulating vitamin D concentrations and risk of breast and prostate cancer: a Mendelian randomization study.
Published in:
2019
By:
- Jiang, Xia;
- Dimou, Niki L;
- Al-Dabhani, Kawthar;
- Lewis, Sarah J;
- Martin, Richard M;
- Haycock, Philip C;
- Gunter, Marc J;
- Key, Timothy J;
- Eeles, Rosalind A;
- Muir, Kenneth;
- Neal, David;
- Giles, Graham G;
- Giovannucci, Edward L;
- Stampfer, Meir;
- Pierce, Brandon L;
- Schildkraut, Joellen M;
- Andersen, Shaneda Warren;
- Thompson, Deborah;
- Zheng, Wei;
- Kraft, Peter
Publication type:
journal article
Sex hormone binding globulin and risk of breast cancer: a Mendelian randomization study.
Published in:
2019
By:
- Dimou, Niki L;
- Papadimitriou, Nikos;
- Gill, Dipender;
- Christakoudi, Sofia;
- Murphy, Neil;
- Gunter, Marc J;
- Travis, Ruth C;
- Key, Tim J;
- Fortner, Renee T;
- Haycock, Philip C;
- Lewis, Sarah J;
- Muir, Kenneth;
- Martin, Richard M;
- Tsilidis, Konstantinos K
Publication type:
journal article
Epigenetics.
Published in:
2015
By:
- Haycock, Philip C.
Publication type:
Book Review
Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator.
Published in:
Genetic Epidemiology, 2016, v. 40, n. 4, p. 304, doi. 10.1002/gepi.21965
By:
- Bowden, Jack;
- Davey Smith, George;
- Haycock, Philip C.;
- Burgess, Stephen
Publication type:
Article
LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis.
Published in:
Bioinformatics, 2017, v. 33, n. 2, p. 272, doi. 10.1093/bioinformatics/btw613
By:
- Jie Zheng;
- Erzurumluoglu, A. Mesut;
- Elsworth, Benjamin L.;
- Kemp, John P.;
- Howe, Laurence;
- Haycock, Philip C.;
- Hemani, Gibran;
- Tansey, Katherine;
- Laurin, Charles;
- Pourcain, Beate St.;
- Warrington, Nicole M.;
- Finucane, Hilary K.;
- Price, Alkes L.;
- Bulik-Sullivan, Brendan K.;
- Anttila, Verneri;
- Paternoster, Lavinia;
- Gaunt, Tom R.;
- Evans, David M.;
- Neale, Benjamin M.
Publication type:
Article
Circulating Selenium and Prostate Cancer Risk: A Mendelian Randomization Analysis.
Published in:
2018
By:
- Yarmolinsky, James;
- Bonilla, Carolina;
- Haycock, Philip C;
- Langdon, Ryan J Q;
- Lotta, Luca A;
- Langenberg, Claudia;
- Relton, Caroline L;
- Lewis, Sarah J;
- Evans, David M;
- Consortium, PRACTICAL;
- PRACTICAL Consortium;
- Davey Smith, George;
- Martin, Richard M
Publication type:
journal article
The Role of Obesity, Type 2 Diabetes, and Metabolic Factors in Pancreatic Cancer: A Mendelian Randomization Study.
Published in:
2017
By:
- Carreras-Torres, Robert;
- Johansson, Mattias;
- Gaborieau, Valerie;
- Haycock, Philip C;
- Wade, Kaitlin H;
- Relton, Caroline L;
- Martin, Richard M;
- Davey Smith, George;
- Brennan, Paul
Publication type:
journal article
Exploiting horizontal pleiotropy to search for causal pathways within a Mendelian randomization framework.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-14452-4
By:
- Cho, Yoonsu;
- Haycock, Philip C.;
- Sanderson, Eleanor;
- Gaunt, Tom R.;
- Zheng, Jie;
- Morris, Andrew P.;
- Davey Smith, George;
- Hemani, Gibran
Publication type:
Article
Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study.
Published in:
PLoS ONE, 2017, v. 12, n. 6, p. 1, doi. 10.1371/journal.pone.0177875
By:
- Carreras-Torres, Robert;
- Johansson, Mattias;
- Haycock, Philip C.;
- Wade, Kaitlin H.;
- Relton, Caroline L.;
- Martin, Richard M.;
- Davey Smith, George;
- Albanes, Demetrius;
- Aldrich, Melinda C.;
- Andrew, Angeline;
- Arnold, Susanne M.;
- Bickeböller, Heike;
- Bojesen, Stig E.;
- Brunnström, Hans;
- Manjer, Jonas;
- Brüske, Irene;
- Caporaso, Neil E.;
- Chen, Chu;
- Christiani, David C.;
- Christian, W. Jay
Publication type:
Article
The Association Between Circulating Lipoprotein(a) and Type 2 Diabetes: Is It Causal?
Published in:
Diabetes, 2014, v. 63, n. 1, p. 332, doi. 10.2337/db13-1144
By:
- Zheng Ye;
- Haycock, Philip C.;
- Gurdasani, Deepti;
- Pomilla, Cristina;
- Boekholdt, S. Matthijs;
- Tsimikas, Sotirios;
- Kay-Tee Khaw;
- Wareham, Nicholas J.;
- Sandhu, Manjinder S.;
- Forouhi, Nita G.
Publication type:
Article

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