Works by Hayashi, Hidetoshi

Results: 131

Efficacy of irreversible EGFR-TKIs for the uncommon secondary resistant EGFR mutations L747S, D761Y, and T854A.

Published in:

2017

By:

Masato Chiba;
Yosuke Togashi;
Eri Bannno;
Yoshihisa Kobayashi;
Yu Nakamura;
Hidetoshi Hayashi;
Masato Terashima;
De Velasco, Marco A.;
Kazuko Sakai;
Yoshihiko Fujita;
Tetsuya Mitsudomi;
Kazuto Nishio;
Chiba, Masato;
Togashi, Yosuke;
Bannno, Eri;
Kobayashi, Yoshihisa;
Nakamura, Yu;
Hayashi, Hidetoshi;
Terashima, Masato;
Sakai, Kazuko

Publication type:

journal article

Prognostic Impact of Minimal Pericardial Effusion in Patients With Advanced Non-small-cell Lung Cancer.

Published in:

2017

By:

Ryoji Kato;
Hidetoshi Hayashi;
Yasutaka Chiba;
Kaoru Tanaka;
Masayuki Takeda;
Kazuhiko Nakagawa;
Kato, Ryoji;
Hayashi, Hidetoshi;
Chiba, Yasutaka;
Tanaka, Kaoru;
Takeda, Masayuki;
Nakagawa, Kazuhiko

Publication type:

journal article

A Randomized Phase II Study Comparing Nivolumab With Carboplatin-Pemetrexed for Patients With EGFR Mutation-Positive Nonsquamous Non-Small-Cell Lung Cancer Who Acquire Resistance to Tyrosine Kinase Inhibitors Not Due to a Secondary T790M Mutation: Rationale and Protocol Design for the WJOG8515L Study.

Published in:

2017

By:

Hidetoshi Hayashi;
Yasutaka Chiba;
Kazuko Sakai;
Tomonobu Fujita;
Fiiroshige Yoshioka;
Daisuke Sakai;
Chiyoe Kitagawa;
Tateaki Naito;
Koji Takeda;
Isamu Okamoto;
Tetsuya Mitsudomi;
Yutaka Kawakami;
Kazuto Nishio;
Shinichiro Nakamura;
Nobuyuki Yamamoto;
Kazuhiko Nakagawa;
Hayashi, Hidetoshi;
Chiba, Yasutaka;
Sakai, Kazuko;
Fujita, Tomonobu

Publication type:

journal article

Progression-Free and Overall Survival of Patients With ALK Rearrangement-Positive Non-Small Cell Lung Cancer Treated Sequentially With Crizotinib and Alectinib.

Published in:

2016

By:

Satomi Watanabe;
Hidetoshi Hayashi;
Kunio Okamoto;
Kimiko Fujiwara;
Yoshikazu Hasegawa;
Hiroyasu Kaneda;
Kaoru Tanaka;
Masayuki Takeda;
Kazuhiko Nakagawa;
Watanabe, Satomi;
Hayashi, Hidetoshi;
Okamoto, Kunio;
Fujiwara, Kimiko;
Hasegawa, Yoshikazu;
Kaneda, Hiroyasu;
Tanaka, Kaoru;
Takeda, Masayuki;
Nakagawa, Kazuhiko

Publication type:

journal article

Exploration of genes related to the development of cancer of unknown primary.

Published in:

Oncology Reports, 2025, v. 53, n. 6, p. N.PAG, doi. 10.3892/or.2025.8905

By:

Fujita, Yoshihiko;
De Velasco, Marco A.;
Hayashi, Hidetoshi;
Nakagawa, Kazuhiko;
Nishio, Kazuto

Publication type:

Article

Alternating Therapy With Osimertinib and Afatinib Blockades EGFR Secondary Mutation in EGFR-Mutant Lung Cancer: A Single-Arm Phase II Trial.

Published in:

Clinical Lung Cancer, 2023, v. 24, n. 6, p. 519, doi. 10.1016/j.cllc.2023.05.008

By:

Kimio Yonesaka;
Hidetoshi Hayashi;
Atsushi Nakamura;
Yuki Sato;
Koichi Azuma;
Shinya Sakata;
Motoko Tachihara;
Satoshi Ikeda;
Toshihide Yokoyama;
Kentaro Ito;
Yukihiro Yano;
Hirotaka Matsumoto;
Haruko Daga;
Akito Hata;
Kazuko Sakai;
Yasutaka Chiba;
Kazuto Nishio;
Nobuyuki Yamamoto;
Kazuhiko Nakagawal

Publication type:

Article

Phase I study of cediranib in combination with cisplatin plus fluoropyrimidine (S-1 or capecitabine) in Japanese patients with previously untreated advanced gastric cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 2, p. 439, doi. 10.1007/s00280-011-1723-8

By:

Satoh, Taroh;
Yamada, Yasuhide;
Muro, Kei;
Hayashi, Hidetoshi;
Shimada, Yasuhiro;
Takahari, Daisuke;
Taku, Keisei;
Nakajima, Takako;
Shi, Xiaojin;
Brown, Kathryn;
Boku, Narikazu

Publication type:

Article

Progression from early to advanced stage of immune‐related cholangitis.

Published in:

Hepatology Research, 2022, v. 52, n. 10, p. 888, doi. 10.1111/hepr.13817

By:

Hagiwara, Satoru;
Yoshida, Takeshi;
Nishida, Naoshi;
Ida, Hiroshi;
Ueshima, Kazuomi;
Minami, Yasunori;
Takita, Masahiro;
Aoki, Tomoko;
Morita, Masahiro;
Cishina, Hirokazu;
Komeda, Yoriaki;
Yoshida, Akihiro;
Hayashi, Hidetoshi;
Nakagawa, Kazuhiko;
Kudo, Masatoshi

Publication type:

Article

Clinical implication of immune checkpoint inhibitor on the chronic hepatitis B virus infection.

Published in:

Hepatology Research, 2022, v. 52, n. 9, p. 754, doi. 10.1111/hepr.13798

By:

Hagiwara, Satoru;
Nishida, Naoshi;
Ida, Hiroshi;
Ueshima, Kazuomi;
Minami, Yasunori;
Takita, Masahiro;
Aoki, Tomoko;
Morita, Masahiro;
Chishina, Hirokazu;
Komeda, Yoriaki;
Yoshida, Akihiro;
Hayashi, Hidetoshi;
Nakagawa, Kazuhiko;
Kudo, Masatoshi

Publication type:

Article

Patritumab Deruxtecan (HER3-DXd) in EGFR-Mutated NSCLC Following EGFR TKI and Platinum-Based Chemotherapy: HERTHENA-Lung01.

Published in:

Journal of Oncology Navigation & Survivorship, 2023, v. 14, n. 11, p. 362

By:

Yu, Helena A.;
Yasushi Goto;
Hidetoshi Hayashi;
Felip, Enriqueta

Publication type:

Article

Interleukin-1 up-regulates transcription of its own receptor in a human fibroblast cell line TIG-1: role of endogenous PGE.

Published in:

European Journal of Immunology, 1992, v. 22, n. 5, p. 1221, doi. 10.1002/eji.1830220517

By:

Takii, Takemasa;
Akahoshi, Tohru;
Kato, Koichi;
Hayashi, Hidetoshi;
Marunouchi, Tohru;
Onozaki, Kikuo

Publication type:

Article

Phase I/II study of intermitted erlotinib in combination with docetaxel in patients with recurrent non-small cell lung cancer (WJOG4708L).

Published in:

Japanese Journal of Clinical Oncology, 2019, v. 49, n. 10, p. 947, doi. 10.1093/jjco/hyz088

By:

Kimura, Tatsuo;
Kawaguchi, Tomoya;
Chiba, Yasutaka;
Yoshioka, Hiroshige;
Watanabe, Katsuya;
Kijima, Takashi;
Kogure, Yoshihito;
Oguri, Tetsuya;
Yoshimura, Naruo;
Niwa, Takashi;
Kasai, Takashi;
Hayashi, Hidetoshi;
Ono, Akira;
Asai, Kazuhisa;
Tanaka, Hiroshi;
Yano, Seiji;
Yamamoto, Nobuyuki;
Nakanishi, Yoichi;
Nakagawa, Kazuhiko

Publication type:

Article

The Combination of ATM and Chk1 Inhibitors Induces Synthetic Lethality in Colorectal Cancer Cells.

Published in:

Cancers, 2023, v. 15, n. 3, p. 735, doi. 10.3390/cancers15030735

By:

Tozaki, Yuri;
Aoki, Hiromasa;
Kato, Rina;
Toriuchi, Kohki;
Arame, Saki;
Inoue, Yasumichi;
Hayashi, Hidetoshi;
Kubota, Eiji;
Kataoka, Hiromi;
Aoyama, Mineyoshi

Publication type:

Article

Two Mechanistically and Temporally Distinct NF-kB Activation Pathways in IL-1 Signaling.

Published in:

Science Signaling, 2009, v. 2, n. 93, p. 1, doi. 10.1126/scisignal.2000387

By:

Yamazaki, Kohsuke;
Gohda, Jin;
Kanayama, Atsuhiro;
Miyamoto, Yusei;
Sakurai, Hiroaki;
Yamamoto, Masahiro;
Akira, Shizuo;
Hayashi, Hidetoshi;
Su, Bing;
Inoue, Jun-ichiro

Publication type:

Article

Hypothermia Attenuates Neurotoxic Microglial Activation via TRPV4.

Published in:

Neurochemical Research, 2024, v. 49, n. 3, p. 800, doi. 10.1007/s11064-023-04075-8

By:

Fukuda, Naoya;
Toriuchi, Kohki;
Mimoto, Rina;
Aoki, Hiromasa;
Kakita, Hiroki;
Suzuki, Yoshiaki;
Takeshita, Satoru;
Tamura, Tetsuya;
Yamamura, Hisao;
Inoue, Yasumichi;
Hayashi, Hidetoshi;
Yamada, Yasumasa;
Aoyama, Mineyoshi

Publication type:

Article

Combined blockade of GPX4 and activated EGFR/HER3 bypass pathways inhibits the development of ALK‐inhibitor‐induced tolerant persister cells in ALK‐fusion‐positive lung cancer.

Published in:

Molecular Oncology, 2025, v. 19, n. 2, p. 519, doi. 10.1002/1878-0261.13746

By:

Furugaki, Koh;
Fujimura, Takaaki;
Sakaguchi, Narumi;
Watanabe, Yasutaka;
Uchibori, Ken;
Miyauchi, Eisaku;
Hayashi, Hidetoshi;
Katayama, Ryohei;
Yoshiura, Shigeki

Publication type:

Article

NOTCH1 and CREBBP co‐mutations negatively affect the benefit of adjuvant therapy in completely resected EGFR‐mutated NSCLC: translational research of phase III IMPACT study.

Published in:

Molecular Oncology, 2024, v. 18, n. 2, p. 305, doi. 10.1002/1878-0261.13542

By:

Ikeda, Satoshi;
Tsuboi, Masahiro;
Sakai, Kazuko;
Misumi, Toshihiro;
Akamatsu, Hiroaki;
Shoda, Hiroyasu;
Sakakura, Noriaki;
Nakamura, Atsushi;
Ohde, Yasuhisa;
Hayashi, Hidetoshi;
Okishio, Kyoichi;
Okada, Morihito;
Yoshino, Ichiro;
Okami, Jiro;
Takahashi, Kazuhisa;
Ikeda, Norihiko;
Tanahashi, Masayuki;
Tambo, Yuichi;
Saito, Haruhiro;
Toyooka, Shinichi

Publication type:

Article

Nintedanib promotes antitumour immunity and shows antitumour activity in combination with PD-1 blockade in mice: potential role of cancer-associated fibroblasts.

Published in:

2021

By:

Kato, Ryoji;
Haratani, Koji;
Hayashi, Hidetoshi;
Sakai, Kazuko;
Sakai, Hitomi;
Kawakami, Hisato;
Tanaka, Kaoru;
Takeda, Masayuki;
Yonesaka, Kimio;
Nishio, Kazuto;
Nakagawa, Kazuhiko

Publication type:

journal article

Real-World Data About Treatment Outcomes for Patients with EGFR-Mutated NSCLC Resistance to Osimertinib and Platinum-Based Chemotherapy.

Published in:

Advances in Therapy, 2023, v. 40, n. 10, p. 4545, doi. 10.1007/s12325-023-02616-9

By:

Hayashi, Hidetoshi;
Nishio, Makoto;
Takahashi, Michiko;
Tsuchiya, Hiroaki;
Kasahara-Kiritani, Mami

Publication type:

Article

TRB3, a novel ER stress-inducible gene, is induced via ATF4-CHOP pathway and is involved in cell death.

Published in:

EMBO Journal, 2005, v. 24, n. 6, p. 1243, doi. 10.1038/sj.emboj.7600596

By:

Ohoka, Nobumichi;
Yoshii, Satoshi;
Hattori, Takayuki;
Onozaki, Kikuo;
Hayashi, Hidetoshi

Publication type:

Article

Perirenal hematoma associated with bevacizumab treatment.

Published in:

2012

By:

Hayashi, Hidetoshi;
Okamoto, Isamu;
Nakagawa, Kazuhiko

Publication type:

Report

Retrospective study of unplanned hospital admission for metastatic cancer patients visiting the emergency department.

Published in:

2017

By:

Tanaka, Tae;
Taguri, Masataka;
Fumita, Soichi;
Okamoto, Kunio;
Matsuo, Yoshio;
Hayashi, Hidetoshi

Publication type:

journal article

Kurarinone from Sophora Flavescens Roots Triggers ATF4 Activation and Cytostatic Effects Through PERK Phosphorylation.

Published in:

Molecules, 2019, v. 24, n. 17, p. 3110, doi. 10.3390/molecules24173110

By:

Nishikawa, Sakiko;
Itoh, Yuka;
Tokugawa, Muneshige;
Inoue, Yasumichi;
Nakashima, Ken-ichi;
Hori, Yuka;
Miyajima, Chiharu;
Yoshida, Kou;
Morishita, Daisuke;
Ohoka, Nobumichi;
Inoue, Makoto;
Mizukami, Hajime;
Makino, Toshiaki;
Hayashi, Hidetoshi;
Xuan, Tran Dang

Publication type:

Article

Anti-Tumorigenic Activity of Chrysin from Oroxylum indicum via Non-Genotoxic p53 Activation through the ATM-Chk2 Pathway.

Published in:

Molecules, 2018, v. 23, n. 6, p. 1394, doi. 10.3390/molecules23061394

By:

Nagasaka, Mai;
Hashimoto, Ryoko;
Inoue, Yasumichi;
Ishiuchi, Kan’ichiro;
Matsuno, Michiyo;
Itoh, Yuka;
Tokugawa, Muneshige;
Ohoka, Nobumichi;
Morishita, Daisuke;
Mizukami, Hajime;
Makino, Toshiaki;
Hayashi, Hidetoshi

Publication type:

Article

Periplocin and cardiac glycosides suppress the unfolded protein response.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-89074-x

By:

Tokugawa, Muneshige;
Inoue, Yasumichi;
Ishiuchi, Kan'ichiro;
Kujirai, Chisane;
Matsuno, Michiyo;
Ri, Masaki;
Itoh, Yuka;
Miyajima, Chiharu;
Morishita, Daisuke;
Ohoka, Nobumichi;
Iida, Shinsuke;
Mizukami, Hajime;
Makino, Toshiaki;
Hayashi, Hidetoshi

Publication type:

Article

Clinicopathological analysis of hepatic immune-related adverse events in comparison with autoimmune hepatitis and graft-versus host disease.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-88824-1

By:

Hagiwara, Satoru;
Watanabe, Tomohiro;
Kudo, Masatoshi;
Minaga, Kosuke;
Komeda, Yoriaki;
Kamata, Ken;
Kimura, Masatomo;
Hayashi, Hidetoshi;
Nakagawa, Kazuhiko;
Ueshima, Kazuomi;
Minami, Yasunori;
Aoki, Tomoko;
Takita, Masahiro;
Morita, Masahiro;
Cishina, Hirokazu;
Ida, Hiroshi;
Park, Ah-Mee;
Nishida, Naoshi

Publication type:

Article

Docetaxel plus cisplatin in recurrent and/or metastatic non-squamous-cell head and neck cancer: a multicenter phase II trial.

Published in:

2021

By:

Imamura, Yoshinori;
Tanaka, Kaoru;
Kiyota, Naomi;
Hayashi, Hidetoshi;
Ota, Ichiro;
Arai, Akihito;
Iwae, Shigemichi;
Minami, Shujiro;
Yane, Katsunari;
Yamazaki, Tomoko;
Nagatani, Yoshiaki;
Toyoda, Masanori;
Takahama, Takayuki;
Sakai, Kazuko;
Nishio, Kazuto;
Otsuki, Naoki;
Nibu, Ken-ichi;
Minami, Hironobu

Publication type:

journal article

A Case of Pulmonary Tumor Thrombotic Microangiopathy Suggested by the Presence of Tumor Cells in Peripheral Blood.

Published in:

Case Reports in Oncology, 2020, v. 13, n. 2, p. 843, doi. 10.1159/000508362

By:

Kawanaka, Yusuke;
Kawakami, Hisato;
Shimizu, Shigeki;
Yoshida, Takeshi;
Hayashi, Hidetoshi;
Nishio, Kazuto;
Satou, Takao;
Nakagawa, Kazuhiko

Publication type:

Article

Dual blockade of EGFR tyrosine kinase using osimertinib and afatinib eradicates EGFR-mutant Ba/F3 cells.

Published in:

Oncology Reports, 2019, v. 41, n. 2, p. 1059

By:

Yonesaka, Kimio;
Kobayashi, Yoshihisa;
Hayashi, Hidetoshi;
Chiba, Yasutaka;
Mitsudomi, Tetsuya;
Nakagawa, Kazuhiko

Publication type:

Article

Antitumor activity of synthetic alkylphospholipids with or without PAF activity.

Published in:

Lipids, 1987, v. 22, n. 11, p. 862, doi. 10.1007/BF02535545

By:

Kudo, Ichiro;
Nojima, Shoshichi;
Chang, Hyeun;
Yanoshita, Ryohei;
Hayashi, Hidetoshi;
Kondo, Eri;
Nomura, Hiroaki;
Inoue, Keizo

Publication type:

Article

Homozygous deletion of the activin A receptor, type IB gene is associated with an aggressive cancer phenotype in pancreatic cancer.

Published in:

Molecular Cancer, 2014, v. 13, n. 1, p. 1, doi. 10.1186/1476-4598-13-126

By:

Togashi, Yosuke;
Sakamoto, Hiroki;
Hayashi, Hidetoshi;
Terashima, Masato;
de Velasco, Marco A.;
Fujita, Yoshihiko;
Kodera, Yasuo;
Sakai, Kazuko;
Tomida, Shuta;
Kitano, Masayuki;
Ito, Akihiko;
Kudo, Masatoshi;
Nishio, Kazuto

Publication type:

Article

A machine learning-based method for feature reduction of methylation data for the classification of cancer tissue origin.

Published in:

International Journal of Clinical Oncology, 2024, v. 29, n. 12, p. 1795, doi. 10.1007/s10147-024-02617-w

By:

De Velasco, Marco A.;
Sakai, Kazuko;
Mitani, Seiichiro;
Kura, Yurie;
Minamoto, Shuji;
Haeno, Takahiro;
Hayashi, Hidetoshi;
Nishio, Kazuto

Publication type:

Article

A phase 2 study of mobocertinib as first-line treatment in Japanese patients with non-small cell lung cancer harboring EGFR exon 20 insertion mutations.

Published in:

International Journal of Clinical Oncology, 2024, v. 29, n. 10, p. 1461, doi. 10.1007/s10147-024-02588-y

By:

Yoh, Kiyotaka;
Azuma, Koichi;
Hayashi, Hidetoshi;
Nishio, Makoto;
Chikamori, Kenichi;
Ichihara, Eiki;
Watanabe, Yasutaka;
Asato, Takayuki;
Kitagawa, Tadayuki;
Fram, Robert J.;
Ohe, Yuichiro

Publication type:

Article

Correction to: First-line nivolumab plus ipilimumab in metastatic non-small cell lung cancer: 5-year outcomes in Japanese patients from CheckMate 227 Part 1.

Published in:

2023

By:

Nishio, Makoto;
Ohe, Yuichiro;
Ikeda, Satoshi;
Yokoyama, Toshihide;
Hayashi, Hidetoshi;
Fukuhara, Tatsuro;
Sato, Yuki;
Tanaka, Hiroshi;
Hotta, Katsuyuki;
Sugawara, Shunichi;
Daga, Haruko;
Okamoto, Isamu;
Kasahara, Kazuo;
Naito, Tateaki;
Li, Li;
Gupta, Ravi G.;
Bushong, Judith;
Mizutani, Hideaki

Publication type:

Correction Notice

First-line nivolumab plus ipilimumab in metastatic non-small cell lung cancer: 5-year outcomes in Japanese patients from CheckMate 227 Part 1.

Published in:

International Journal of Clinical Oncology, 2023, v. 28, n. 10, p. 1354, doi. 10.1007/s10147-023-02390-2

By:

Nishio, Makoto;
Ohe, Yuichiro;
Ikeda, Satoshi;
Yokoyama, Toshihide;
Hayashi, Hidetoshi;
Fukuhara, Tatsuro;
Sato, Yuki;
Tanaka, Hiroshi;
Hotta, Katsuyuki;
Sugawara, Shunichi;
Daga, Haruko;
Okamoto, Isamu;
Kasahara, Kazuo;
Naito, Tateaki;
Li, Li;
Gupta, Ravi G.;
Bushong, Judith;
Mizutani, Hideaki

Publication type:

Article

CAPP-seq analysis of circulating tumor DNA from patients with EGFR T790M–positive lung cancer after osimertinib.

Published in:

International Journal of Clinical Oncology, 2021, v. 26, n. 9, p. 1628, doi. 10.1007/s10147-021-01947-3

By:

Kato, Ryoji;
Hayashi, Hidetoshi;
Sakai, Kazuko;
Suzuki, Shinichiro;
Haratani, Koji;
Takahama, Takayuki;
Tanizaki, Junko;
Nonagase, Yoshikane;
Tanaka, Kaoru;
Yoshida, Takeshi;
Takeda, Masayuki;
Yonesaka, Kimio;
Kaneda, Hiroyasu;
Nishio, Kazuto;
Nakagawa, Kazuhiko

Publication type:

Article

First-line durvalumab plus platinum-etoposide in extensive-stage small-cell lung cancer: CASPIAN Japan subgroup analysis.

Published in:

International Journal of Clinical Oncology, 2021, v. 26, n. 6, p. 1073, doi. 10.1007/s10147-021-01899-8

By:

Hotta, Katsuyuki;
Nishio, Makoto;
Saito, Haruhiro;
Okamoto, Isamu;
Nakahara, Yasuharu;
Hayashi, Hidetoshi;
Hayama, Manabu;
Laud, Peter;
Jiang, Haiyi;
Paz-Ares, Luis;
Azuma, Koichi

Publication type:

Article

Combination therapy with PD-1 or PD-L1 inhibitors for cancer.

Published in:

International Journal of Clinical Oncology, 2020, v. 25, n. 5, p. 818, doi. 10.1007/s10147-019-01548-1

By:

Hayashi, Hidetoshi;
Nakagawa, Kazuhiko

Publication type:

Article

High-dose dexamethasone plus antihistamine prevents colorectal cancer patients treated with modified FOLFOX6 from hypersensitivity reactions induced by oxaliplatin.

Published in:

International Journal of Clinical Oncology, 2011, v. 16, n. 3, p. 244, doi. 10.1007/s10147-010-0170-6

By:

Kidera, Yasuhiro;
Satoh, Taroh;
Ueda, Shinya;
Okamoto, Wataru;
Okamoto, Isamu;
Fumita, Soichi;
Yonesaka, Kimio;
Hayashi, Hidetoshi;
Makimura, Chihiro;
Okamoto, Kunio;
Kiyota, Hidemi;
Tsurutani, Junji;
Miyazaki, Masaki;
Yoshinaga, Masahiro;
Fujiwara, Kimiko;
Yamazoe, Yuzuru;
Moriyama, Kenzo;
Tsubaki, Masanobu;
Chiba, Yasutaka;
Nishida, Shozo

Publication type:

Article

Retreatment of recurrent malignant pleural mesothelioma with cisplatin and pemetrexed.

Published in:

International Journal of Clinical Oncology, 2010, v. 15, n. 5, p. 497, doi. 10.1007/s10147-010-0064-7

By:

Hayashi, Hidetoshi;
Okamoto, Isamu;
Ichikawa, Yasuko;
Miyazaki, Masaki;
Yoshioka, Hiroshige;
Kunimasa, Kei;
Nakagawa, Kazuhiko

Publication type:

Article

Synthesis of glycosylated human tumor necrosis factor α coupled with N-acetylneuraminic acid.

Published in:

Cancer Immunology, Immunotherapy, 2007, v. 56, n. 4, p. 545, doi. 10.1007/s00262-006-0209-8

By:

Hayashi, Akiko;
Chiba, Taku;
Hayashi, Hidetoshi;
Sasayama, Satoshi;
Ishiguro, Toshiyuki;
Onozaki, Kikuo

Publication type:

Article

N-acetylneuraminic acid coupled human recombinant TNFα exhibits enhanced anti-tumor activity against Meth-A fibrosarcoma and reduced toxicity.

Published in:

Cancer Immunology, Immunotherapy, 2007, v. 56, n. 4, p. 555, doi. 10.1007/s00262-006-0210-2

By:

Hayashi, Akiko;
Hayashi, Hidetoshi;
Chiba, Taku;
Sasayama, Satoshi;
Onozaki, Kikuo

Publication type:

Article

MEK inhibitors against MET-amplified non-small cell lung cancer.

Published in:

International Journal of Oncology, 2016, v. 49, n. 6, p. 2236, doi. 10.3892/ijo.2016.3736

By:

MASATO CHIBA;
YOSUKE TOGASHI;
SHUTA TOMIDA;
HIROSHI MIZUUCHI;
YU NAKAMURA;
ERI BANNO;
HIDETOSHI HAYASHI;
MASATO TERASHIMA;
DE VELASCO, MARCO A.;
KAZUKO SAKAI;
YOSHIHIKO FUJITA;
TETSUYA MITSUDOMI;
KAZUTO NISHIO

Publication type:

Article

Activated MET acts as a salvage signal after treatment with alectinib, a selective ALK inhibitor, in ALK-positive non-small cell lung cancer.

Published in:

International Journal of Oncology, 2015, v. 46, n. 3, p. 1025, doi. 10.3892/ijo.2014.2797

By:

AKIHIRO KOGITA;
YOSUKE TOGASHI;
HIDETOSHI HAYASHI;
ERI BANNO;
MASATO TERASHIMA;
DE VELASCO, MARCO A.;
KAZUKO SAKAI;
YOSHIHIKO FUJITA;
SHUTA TOMIDA;
YOSHIFUMI TAKEYAMA;
KIYOTAKA OKUNO;
KAZUHIKO NAKAGAWA;
KAZUTO NISHIO

Publication type:

Article

Hypoxia induces resistance to ALK inhibitors in the H3122 non-small cell lung cancer cell line with an ALK rearrangement via epithelial-mesenchymal transition.

Published in:

International Journal of Oncology, 2014, v. 45, n. 4, p. 1430, doi. 10.3892/ijo.2014.2574

By:

AKIHIRO KOGITA;
YOSUKE TOGASHI;
HIDETOSHI HAYASHI;
SHUNSUKE SOGABE;
MASATO TERASHIMA;
DE VELASCO, MARCO A.;
KAZUKO SAKAI;
YOSHIHIKO FUJITA;
SHUTA TOMIDA;
YOSHIFUMI TAKEYAMA;
KIYOTAKA OKUNO;
KAZUHIKO NAKAGAWA;
KAZUTO NISHIO

Publication type:

Article

C/EBP family transcription factors are degraded by the proteasome but stabilized by forming dimer.

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Oncogene, 2003, v. 22, n. 9, p. 1273, doi. 10.1038/sj.onc.1206204

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Hattori, Takayuki;
Ohoka, Nobumichi;
Inoue, Yasumichi;
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Onozaki, Kikuo

Publication type:

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Detection of Overlooked Rare EGFR Mutations in Non‐small Cell Lung Cancer Using Multigene Testing.

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Thoracic Cancer, 2025, v. 16, n. 3, p. 1, doi. 10.1111/1759-7714.70007

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Shiraishi, Naoki;
Takahama, Takayuki;
Sakai, Kazuko;
Tanaka, Kaoru;
Nakagawa, Yuzuki;
Kanemura, Hiroaki;
Nakayama, Tomohiro;
Kawanaka, Yusuke;
Kurosaki, Takashi;
Suzuki, Shinichiro;
Iwasa, Tsutomu;
Tanizaki, Junko;
Inagaki, Chiaki;
Yonesaka, Kimio;
Fukuoka, Kazuya;
Mitsudomi, Tetsuya;
Nishio, Kazuto;
Hayashi, Hidetoshi;
Nakagawa, Kazuhiko

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Article

Tumor tissue and plasma levels of AXL and GAS6 before and after tyrosine kinase inhibitor treatment in EGFR‐mutated non–small cell lung cancer.

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Thoracic Cancer, 2019, v. 10, n. 10, p. 1928, doi. 10.1111/1759-7714.13166

By:

Nonagase, Yoshikane;
Takeda, Masayuki;
Azuma, Koichi;
Hayashi, Hidetoshi;
Haratani, Koji;
Tanaka, Kaoru;
Yonesaka, Kimio;
Ishii, Hidenobu;
Hoshino, Tomoaki;
Nakagawa, Kazuhiko

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Clinical outcome of node-negative oligometastatic non-small cell lung cancer.

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Thoracic Cancer, 2016, v. 7, n. 6, p. 670, doi. 10.1111/1759-7714.12386

By:

Sakai, Kiyohiro;
Takeda, Masayuki;
Hayashi, Hidetoshi;
Tanaka, Kaoru;
Okuda, Takeshi;
Kato, Amami;
Nishimura, Yasumasa;
Mitsudomi, Tetsuya;
Koyama, Atsuko;
Nakagawa, Kazuhiko

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Article

Rationale and Design for a Multicenter, Phase II Study of Durvalumab Plus Concurrent Radiation Therapy in Locally Advanced Non-Small Cell Lung Cancer: The DOLPHIN Study (WJOG11619L).

Published in:

Cancer Management & Research, 2021, v. 13, p. 9167, doi. 10.2147/CMAR.S336262

By:

Tachihara, Motoko;
Tsujino, Kayoko;
Ishihara, Takeaki;
Hayashi, Hidetoshi;
Sato, Yuki;
Kurata, Takayasu;
Sugawara, Shunichi;
Okamoto, Isamu;
Teraoka, Shunsuke;
Azuma, Koichi;
Daga, Haruko;
Yamaguchi, Masafumi;
Kodaira, Takeshi;
Satouchi, Miyako;
Shimokawa, Mototsugu;
Yamamoto, Nobuyuki;
Nakagawa, Kazuhiko

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Article