Works matching AU Hayashi, Hidetoshi

Results: 131

Prognostic Impact of Minimal Pericardial Effusion in Patients With Advanced Non-small-cell Lung Cancer.

Published in:

2017

By:

Ryoji Kato;
Hidetoshi Hayashi;
Yasutaka Chiba;
Kaoru Tanaka;
Masayuki Takeda;
Kazuhiko Nakagawa;
Kato, Ryoji;
Hayashi, Hidetoshi;
Chiba, Yasutaka;
Tanaka, Kaoru;
Takeda, Masayuki;
Nakagawa, Kazuhiko

Publication type:

journal article

A Randomized Phase II Study Comparing Nivolumab With Carboplatin-Pemetrexed for Patients With EGFR Mutation-Positive Nonsquamous Non-Small-Cell Lung Cancer Who Acquire Resistance to Tyrosine Kinase Inhibitors Not Due to a Secondary T790M Mutation: Rationale and Protocol Design for the WJOG8515L Study.

Published in:

2017

By:

Hidetoshi Hayashi;
Yasutaka Chiba;
Kazuko Sakai;
Tomonobu Fujita;
Fiiroshige Yoshioka;
Daisuke Sakai;
Chiyoe Kitagawa;
Tateaki Naito;
Koji Takeda;
Isamu Okamoto;
Tetsuya Mitsudomi;
Yutaka Kawakami;
Kazuto Nishio;
Shinichiro Nakamura;
Nobuyuki Yamamoto;
Kazuhiko Nakagawa;
Hayashi, Hidetoshi;
Chiba, Yasutaka;
Sakai, Kazuko;
Fujita, Tomonobu

Publication type:

journal article

Progression-Free and Overall Survival of Patients With ALK Rearrangement-Positive Non-Small Cell Lung Cancer Treated Sequentially With Crizotinib and Alectinib.

Published in:

2016

By:

Satomi Watanabe;
Hidetoshi Hayashi;
Kunio Okamoto;
Kimiko Fujiwara;
Yoshikazu Hasegawa;
Hiroyasu Kaneda;
Kaoru Tanaka;
Masayuki Takeda;
Kazuhiko Nakagawa;
Watanabe, Satomi;
Hayashi, Hidetoshi;
Okamoto, Kunio;
Fujiwara, Kimiko;
Hasegawa, Yoshikazu;
Kaneda, Hiroyasu;
Tanaka, Kaoru;
Takeda, Masayuki;
Nakagawa, Kazuhiko

Publication type:

journal article

Efficacy of irreversible EGFR-TKIs for the uncommon secondary resistant EGFR mutations L747S, D761Y, and T854A.

Published in:

2017

By:

Masato Chiba;
Yosuke Togashi;
Eri Bannno;
Yoshihisa Kobayashi;
Yu Nakamura;
Hidetoshi Hayashi;
Masato Terashima;
De Velasco, Marco A.;
Kazuko Sakai;
Yoshihiko Fujita;
Tetsuya Mitsudomi;
Kazuto Nishio;
Chiba, Masato;
Togashi, Yosuke;
Bannno, Eri;
Kobayashi, Yoshihisa;
Nakamura, Yu;
Hayashi, Hidetoshi;
Terashima, Masato;
Sakai, Kazuko

Publication type:

journal article

High-dose dexamethasone plus antihistamine prevents colorectal cancer patients treated with modified FOLFOX6 from hypersensitivity reactions induced by oxaliplatin.

Published in:

International Journal of Clinical Oncology, 2011, v. 16, n. 3, p. 244, doi. 10.1007/s10147-010-0170-6

By:

Kidera, Yasuhiro;
Satoh, Taroh;
Ueda, Shinya;
Okamoto, Wataru;
Okamoto, Isamu;
Fumita, Soichi;
Yonesaka, Kimio;
Hayashi, Hidetoshi;
Makimura, Chihiro;
Okamoto, Kunio;
Kiyota, Hidemi;
Tsurutani, Junji;
Miyazaki, Masaki;
Yoshinaga, Masahiro;
Fujiwara, Kimiko;
Yamazoe, Yuzuru;
Moriyama, Kenzo;
Tsubaki, Masanobu;
Chiba, Yasutaka;
Nishida, Shozo

Publication type:

Article

Retreatment of recurrent malignant pleural mesothelioma with cisplatin and pemetrexed.

Published in:

International Journal of Clinical Oncology, 2010, v. 15, n. 5, p. 497, doi. 10.1007/s10147-010-0064-7

By:

Hayashi, Hidetoshi;
Okamoto, Isamu;
Ichikawa, Yasuko;
Miyazaki, Masaki;
Yoshioka, Hiroshige;
Kunimasa, Kei;
Nakagawa, Kazuhiko

Publication type:

Article

Targeting ErbB and tankyrase1/2 prevent the emergence of drug-tolerant persister cells in ALK-positive lung cancer.

Published in:

NPJ Precision Oncology, 2024, v. 8, n. 1, p. 1, doi. 10.1038/s41698-024-00757-w

By:

Fujimura, Takaaki;
Furugaki, Koh;
Mizuta, Hayato;
Muraoka, Satoshi;
Nishio, Makoto;
Adachi, Jun;
Uchibori, Ken;
Miyauchi, Eisaku;
Hayashi, Hidetoshi;
Katayama, Ryohei;
Yoshiura, Shigeki

Publication type:

Article

Alternating Therapy With Osimertinib and Afatinib Blockades EGFR Secondary Mutation in EGFR-Mutant Lung Cancer: A Single-Arm Phase II Trial.

Published in:

Clinical Lung Cancer, 2023, v. 24, n. 6, p. 519, doi. 10.1016/j.cllc.2023.05.008

By:

Kimio Yonesaka;
Hidetoshi Hayashi;
Atsushi Nakamura;
Yuki Sato;
Koichi Azuma;
Shinya Sakata;
Motoko Tachihara;
Satoshi Ikeda;
Toshihide Yokoyama;
Kentaro Ito;
Yukihiro Yano;
Hirotaka Matsumoto;
Haruko Daga;
Akito Hata;
Kazuko Sakai;
Yasutaka Chiba;
Kazuto Nishio;
Nobuyuki Yamamoto;
Kazuhiko Nakagawal

Publication type:

Article

Overall Treatment Strategy for Patients With Metastatic NSCLC With Activating EGFR Mutations.

Published in:

Clinical Lung Cancer, 2022, v. 23, n. 1, p. e69, doi. 10.1016/j.cllc.2021.10.009

By:

Hayashi, Hidetoshi;
Nadal, Ernest;
Gray, Jhanelle E.;
Ardizzoni, Andrea;
Caria, Nicola;
Puri, Tarun;
Grohe, Christian

Publication type:

Article

Treatment Rationale and Design for APPLE (WJOG11218L): A Multicenter, Open-Label, Randomized Phase 3 Study of Atezolizumab and Platinum/Pemetrexed With or Without Bevacizumab for Patients With Advanced Nonsquamous Non-Small-Cell Lung Cancer.

Published in:

2020

By:

Shiraishi, Yoshimasa;
Kishimoto, Junji;
Tanaka, Kentaro;
Sugawara, Shunichi;
Daga, Haruko;
Hirano, Katsuya;
Azuma, Koichi;
Hataji, Osamu;
Hayashi, Hidetoshi;
Tachihara, Motoko;
Mitsudomi, Tetsuya;
Seto, Takashi;
Nakagawa, Kazuhiko;
Yamamoto, Nobuyuki;
Okamoto, Isamu

Publication type:

journal article

Subgroup Analysis of Japanese Patients in a Phase III Study of Atezolizumab in Extensive-stage Small-cell Lung Cancer (IMpower133).

Published in:

2019

By:

Nishio, Makoto;
Sugawara, Shunichi;
Atagi, Shinji;
Akamatsu, Hiroaki;
Sakai, Hiroshi;
Okamoto, Isamu;
Takayama, Koichi;
Hayashi, Hidetoshi;
Nakagawa, Yuki;
Kawakami, Tomohisa

Publication type:

journal article

Postprogression survival in patients with advanced non-small-cell lung cancer who receive second-line or third-line chemotherapy.

Published in:

2013

By:

Hayashi, Hidetoshi;
Okamoto, Isamu;
Taguri, Masataka;
Morita, Satoshi;
Nakagawa, Kazuhiko

Publication type:

Journal Article

Postprogression Survival in Patients With Advanced Non-Small-Cell Lung Cancer Who Receive Second-Line or Third-Line Chemotherapy.

Published in:

Clinical Lung Cancer, 2013, v. 14, n. 3, p. 261, doi. 10.1016/j.cllc.2012.09.006

By:

Hidetoshi Hayashi;
Isamu Okamoto;
Masataka Taguri;
Satoshi Morita;
Kazuhiko Nakagawa

Publication type:

Article

Novel single nucleotide polymorphism biomarkers to predict opioid effects for cancer pain.

Published in:

Oncology Letters, 2023, v. 26, n. 2, p. 1, doi. 10.3892/ol.2023.13941

By:

YOSHIHIKO FUJITA;
HIROMICHI MATSUOKA;
YASUTAKA CHIBA;
JUNJI TSURUTANI;
TAKESHI YOSHIDA;
KIYOHIRO SAKAI;
MIKI NAKURA;
RYO SAKAMOTO;
CHIHIRO MAKIMURA;
YOICHI OHTAKE;
KAORU TANAKA;
HIDETOSHI HAYASHI;
MASAYUKI TAKEDA;
TATSUYA OKUNO;
NAOKI TAKEGAWA;
KOJI HARATANI;
TAKAYUKI TAKAHAMA;
JUNKO TANIZAKI;
ATSUKO KOYAMA;
KAZUTO NISHIO

Publication type:

Article

Dual single‑nucleotide polymorphism biomarker combination for opioid selection to treat cancer pain.

Published in:

Molecular & Clinical Oncology, 2025, v. 22, n. 2, p. N.PAG, doi. 10.3892/mco.2024.2809

By:

Fujita, Yoshihiko;
Matsuoka, Hiromichi;
Chiba, Yasutaka;
Tsurutani, Junji;
Yoshida, Takeshi;
Sakai, Kiyohiro;
Nakura, Miki;
Sakamoto, Ryo;
Makimura, Chihiro;
Ohtake, Yoichi;
Tanaka, Kaoru;
Hayashi, Hidetoshi;
Takahama, Takayuki;
Tanizaki, Junko;
Koyama, Atsuko;
Nishio, Kazuto;
Nakagawa, Kazuhiko

Publication type:

Article

Resistance to IL-1 anti-proliferative effect, accompanied by characteristics of advanced melanoma, permits invasion of human melanoma cells in vitro, but not metastasis in the nude mouse.

Published in:

International Journal of Cancer, 1997, v. 71, n. 3, p. 416, doi. 10.1002/(SICI)1097-0215(19970502)71:3<416::AID-IJC19>3.0.CO;2-D

By:

Hayashi, Hidetoshi;
Shimizu, Reiko;
Fujii, Kaori;
Itoh, Saotomo;
Yang, De;
Onozaki, Kikuo

Publication type:

Article

Interleukin 1 (IL-1) production is not essential for acquired resistance of human A375 melanoma cells to anti-proliferative effect of IL-1.

Published in:

International Journal of Cancer, 1996, v. 65, n. 6, p. 805, doi. 10.1002/(SICI)1097-0215(19960315)65:6<805::AID-IJC17>3.0.CO;2-2

By:

Itoh, Saotomo;
Hayashi, Hidetoshi;
Watanabe, Naoko;
Kobayashi, Yoshiro;
Takii, Takemasa;
Onozaki, Kikuo

Publication type:

Article

Resistance to the anti-proliferative effect of IL-1 on human melanoma cell line is associated with endogenous production of IL-1 and IL-6.

Published in:

International Journal of Cancer, 1994, v. 56, n. 2, p. 275, doi. 10.1002/ijc.2910560222

By:

Araki, Makoto;
Yano, Taishi;
Hayashi, Hidetoshi;
Takii, Takemasa;
Suzuki, Katsuya;
Onozaki, Kikuo

Publication type:

Article

Phase I/II study of intermitted erlotinib in combination with docetaxel in patients with recurrent non-small cell lung cancer (WJOG4708L).

Published in:

Japanese Journal of Clinical Oncology, 2019, v. 49, n. 10, p. 947, doi. 10.1093/jjco/hyz088

By:

Kimura, Tatsuo;
Kawaguchi, Tomoya;
Chiba, Yasutaka;
Yoshioka, Hiroshige;
Watanabe, Katsuya;
Kijima, Takashi;
Kogure, Yoshihito;
Oguri, Tetsuya;
Yoshimura, Naruo;
Niwa, Takashi;
Kasai, Takashi;
Hayashi, Hidetoshi;
Ono, Akira;
Asai, Kazuhisa;
Tanaka, Hiroshi;
Yano, Seiji;
Yamamoto, Nobuyuki;
Nakanishi, Yoichi;
Nakagawa, Kazuhiko

Publication type:

Article

Clinical implications of bronchoscopy for immune checkpoint inhibitor-related pneumonitis in patients with non-small cell lung cancer.

Published in:

2021

By:

Nishiyama, Osamu;
Shimizu, Shigeki;
Haratani, Koji;
Isomoto, Kosuke;
Tanizaki, Junko;
Hayashi, Hidetoshi;
Yamazaki, Ryo;
Oomori, Takashi;
Nishikawa, Yusaku;
Sano, Akiko;
Nakagawa, Kazuhiko;
Tohda, Yuji

Publication type:

journal article

Synthesis of glycosylated human tumor necrosis factor α coupled with N-acetylneuraminic acid.

Published in:

Cancer Immunology, Immunotherapy, 2007, v. 56, n. 4, p. 545, doi. 10.1007/s00262-006-0209-8

By:

Hayashi, Akiko;
Chiba, Taku;
Hayashi, Hidetoshi;
Sasayama, Satoshi;
Ishiguro, Toshiyuki;
Onozaki, Kikuo

Publication type:

Article

N-acetylneuraminic acid coupled human recombinant TNFα exhibits enhanced anti-tumor activity against Meth-A fibrosarcoma and reduced toxicity.

Published in:

Cancer Immunology, Immunotherapy, 2007, v. 56, n. 4, p. 555, doi. 10.1007/s00262-006-0210-2

By:

Hayashi, Akiko;
Hayashi, Hidetoshi;
Chiba, Taku;
Sasayama, Satoshi;
Onozaki, Kikuo

Publication type:

Article

Transcriptional Coactivator TAZ Negatively Regulates Tumor Suppressor p53 Activity and Cellular Senescence.

Published in:

Cells (2073-4409), 2020, v. 9, n. 1, p. 1, doi. 10.3390/cells9010171

By:

Chiharu Miyajima;
Yuki Kawarada;
Yasumichi Inoue;
Chiaki Suzuki;
Kana Mitamura;
Daisuke Morishita;
Nobumichi Ohoka;
Takeshi Imamura;
Hidetoshi Hayashi

Publication type:

Article

Melanoma Transition Is Frequently Accompanied by a Loss of Cytoglobin Expression in Melanocytes: A Novel Expression Site of Cytoglobin.

Published in:

PLoS ONE, 2014, v. 9, n. 4, p. 1, doi. 10.1371/journal.pone.0094772

By:

Fujita, Yoshihiko;
Koinuma, Satoshi;
De Velasco, Marco A.;
Bolz, Jan;
Togashi, Yosuke;
Terashima, Masato;
Hayashi, Hidetoshi;
Matsuo, Takuya;
Nishio, Kazuto

Publication type:

Article

Phase II study of bi-weekly irinotecan for patients with previously treated HER2-negative metastatic breast cancer: KMBOG0610B.

Published in:

Breast Cancer (13406868), 2013, v. 20, n. 2, p. 131, doi. 10.1007/s12282-011-0316-z

By:

Hayashi, Hidetoshi;
Tsurutani, Junji;
Satoh, Taro;
Masuda, Norikazu;
Okamoto, Wataru;
Morinaga, Ryotaro;
Terashima, Masaaki;
Miyazaki, Masaki;
Okamoto, Isamu;
Nishida, Yukihiro;
Tominaga, Shusei;
Tokunaga, Yukihiko;
Yamaguchi, Masahide;
Sakamoto, Junichi;
Nakayama, Takahiro;
Nakagawa, Kazuhiko

Publication type:

Article

Bevacizumab beyond disease progression after first-line treatment with bevacizumab plus chemotherapy in advanced nonsquamous non-small cell lung cancer (West Japan Oncology Group 5910L): An open-label, randomized, phase 2 trial.

Published in:

2016

By:

Takeda, Masayuki;
Yamanaka, Takeharu;
Seto, Takashi;
Hayashi, Hidetoshi;
Azuma, Koichi;
Okada, Morihito;
Sugawara, Shunichi;
Daga, Haruko;
Hirashima, Tomonori;
Yonesaka, Kimio;
Urata, Yoshiko;
Murakami, Haruyasu;
Saito, Haruhiro;
Kubo, Akihito;
Sawa, Toshiyuki;
Miyahara, Eiji;
Nogami, Naoyuki;
Nakagawa, Kazuhiko;
Nakanishi, Yoichi;
Okamoto, Isamu

Publication type:

journal article

Clinicopathological and genetic differences between low-grade and high-grade colorectal mucinous adenocarcinomas.

Published in:

2015

By:

Yoshioka, Yasumasa;
Togashi, Yosuke;
Chikugo, Takaaki;
Kogita, Akihiro;
Taguri, Masataka;
Terashima, Masato;
Mizukami, Takuro;
Hayashi, Hidetoshi;
Sakai, Kazuko;
de Velasco, Marco A.;
Tomida, Shuta;
Fujita, Yoshihiko;
Tokoro, Tadao;
Ito, Akihiko;
Okuno, Kiyotaka;
Nishio, Kazuto

Publication type:

journal article

TRAF6-NF-κB pathway is essential for interleukin-1-induced TLR2 expression and its functional response to TLR2 ligand in murine hepatocytes.

Published in:

Immunology, 2003, v. 109, n. 1, p. 127, doi. 10.1046/j.1365-2567.2003.01627.x

By:

Matsumura, Takayuki;
Degawa, Takahiro;
Takii, Takemasa;
Hayashi, Hidetoshi;
Okamoto, Takashi;
Inoue, Jun-ichiro;
Onozaki, Kikuo

Publication type:

Article

Progression from early to advanced stage of immune‐related cholangitis.

Published in:

Hepatology Research, 2022, v. 52, n. 10, p. 888, doi. 10.1111/hepr.13817

By:

Hagiwara, Satoru;
Yoshida, Takeshi;
Nishida, Naoshi;
Ida, Hiroshi;
Ueshima, Kazuomi;
Minami, Yasunori;
Takita, Masahiro;
Aoki, Tomoko;
Morita, Masahiro;
Cishina, Hirokazu;
Komeda, Yoriaki;
Yoshida, Akihiro;
Hayashi, Hidetoshi;
Nakagawa, Kazuhiko;
Kudo, Masatoshi

Publication type:

Article

Clinical implication of immune checkpoint inhibitor on the chronic hepatitis B virus infection.

Published in:

Hepatology Research, 2022, v. 52, n. 9, p. 754, doi. 10.1111/hepr.13798

By:

Hagiwara, Satoru;
Nishida, Naoshi;
Ida, Hiroshi;
Ueshima, Kazuomi;
Minami, Yasunori;
Takita, Masahiro;
Aoki, Tomoko;
Morita, Masahiro;
Chishina, Hirokazu;
Komeda, Yoriaki;
Yoshida, Akihiro;
Hayashi, Hidetoshi;
Nakagawa, Kazuhiko;
Kudo, Masatoshi

Publication type:

Article

Overexpression of heparan sulfate 6-O-sulfotransferase-2 in colorectal cancer.

Published in:

Molecular & Clinical Oncology, 2013, v. 1, n. 5, p. 845, doi. 10.3892/mco.2013.151

By:

SHIGERU HATABE;
HIDEHARU KIMURA;
TOKUZO ARAO;
HIROAKI KATO;
HIDETOSHI HAYASHI;
TOMOYUKI NAGAI;
KAZUKO MATSUMOTO;
DE VELASCO, MARCO;
YOSHIHIKO FUJITA;
GO YAMANOUCHI;
MASAO FUKUSHIMA;
YASUHIDE YAMADA;
AKIHIKO ITO;
KIYOTAKA OKUNO;
KAZUTO NISHIO

Publication type:

Article

Clinical utility of erlotinib for the treatment of non-small-cell lung cancer in Japanese patients: current evidence.

Published in:

Drug Design, Development & Therapy, 2014, v. 8, p. 1037, doi. 10.2147/DDDT.S50358

By:

Yosuke Togashi;
Hidetoshi Hayashi;
Kazuhiko Nakagawa;
Kazuto Nishio

Publication type:

Article

Two Mechanistically and Temporally Distinct NF-kB Activation Pathways in IL-1 Signaling.

Published in:

Science Signaling, 2009, v. 2, n. 93, p. 1, doi. 10.1126/scisignal.2000387

By:

Yamazaki, Kohsuke;
Gohda, Jin;
Kanayama, Atsuhiro;
Miyamoto, Yusei;
Sakurai, Hiroaki;
Yamamoto, Masahiro;
Akira, Shizuo;
Hayashi, Hidetoshi;
Su, Bing;
Inoue, Jun-ichiro

Publication type:

Article

Identification of a Novel Growth-Promoting Factor with a Wide Target Cell Spectrum from Various Tumor Cells as Catalase1.

Published in:

Journal of Biochemistry, 1996, v. 120, n. 4, p. 725, doi. 10.1093/oxfordjournals.jbchem.a021471

By:

Miyamoto, Tomomi;
Hayashi, Masaru;
Takeuchi, Akihiko;
Okamoto, Takayuki;
kawashima, Sachiko;
Takii, Takemasa;
Hayashi, Hidetoshi;
Onozaki, Kikuo

Publication type:

Article

Association of immune-related adverse events with immune checkpoint inhibitor efficacy: real or imaginary?

Published in:

2020

By:

Haratani, Koji;
Hayashi, Hidetoshi;
Nakagawa, Kazuhiko

Publication type:

Letter

Predictive value of EGFR mutation in non–small‐cell lung cancer patients treated with platinum doublet postoperative chemotherapy.

Published in:

Cancer Science, 2022, v. 113, n. 1, p. 287, doi. 10.1111/cas.15171

By:

Takahashi, Toshiaki;
Sakai, Kazuko;
Kenmotsu, Hirotsugu;
Yoh, Kiyotaka;
Daga, Haruko;
Ohira, Tatsuo;
Ueno, Tsuyoshi;
Aoki, Tadashi;
Hayashi, Hidetoshi;
Yamazaki, Koji;
Hosomi, Yukio;
Chen‐Yoshikawa, Toyofumi F.;
Okumura, Norihito;
Takiguchi, Yuichi;
Sekine, Akimasa;
Haruki, Tomohiro;
Yamamoto, Hiromasa;
Sato, Yuki;
Akamatsu, Hiroaki;
Seto, Takashi

Publication type:

Article

Lorlatinib in previously treated anaplastic lymphoma kinase‐rearranged non–small cell lung cancer: Japanese subgroup analysis of a global study.

Published in:

Cancer Science, 2020, v. 111, n. 10, p. 3726, doi. 10.1111/cas.14576

By:

Seto, Takashi;
Hayashi, Hidetoshi;
Satouchi, Miyako;
Goto, Yasushi;
Niho, Seiji;
Nogami, Naoyuki;
Hida, Toyoaki;
Takahashi, Toshiaki;
Sakakibara‐Konishi, Jun;
Morise, Masahiro;
Nagasawa, Takashi;
Suzuki, Mie;
Ohkura, Masayuki;
Fukuhara, Kei;
Thurm, Holger;
Peltz, Gerson;
Nishio, Makoto

Publication type:

Article

Mutational activation of the epidermal growth factor receptor down‐regulates major histocompatibility complex class I expression via the extracellular signal‐regulated kinase in non–small cell lung cancer.

Published in:

Cancer Science, 2019, v. 110, n. 1, p. 52, doi. 10.1111/cas.13860

By:

Watanabe, Satomi;
Hayashi, Hidetoshi;
Haratani, Koji;
Shimizu, Shigeki;
Tanizaki, Junko;
Sakai, Kazuko;
Kawakami, Hisato;
Yonesaka, Kimio;
Tsurutani, Junji;
Togashi, Yosuke;
Nishio, Kazuto;
Ito, Akihiko;
Nakagawa, Kazuhiko

Publication type:

Article

Clinical activity of ASP8273 in Asian patients with non‐small‐cell lung cancer with EGFR activating and T790M mutations.

Published in:

Cancer Science, 2018, v. 109, n. 9, p. 2852, doi. 10.1111/cas.13724

By:

Murakami, Haruyasu;
Nokihara, Hiroshi;
Hayashi, Hidetoshi;
Seto, Takashi;
Park, Keunchil;
Azuma, Koichi;
Tsai, Chun‐Ming;
Yang, James Chih‐Hsin;
Nishio, Makoto;
Kim, Sang‐We;
Kiura, Katsuyuki;
Inoue, Akira;
Takeda, Koji;
Kang, Jin‐Hyoung;
Nakagawa, Tomoki;
Takeda, Kentaro;
Akazawa, Rio;
Kaneko, Yuichiro;
Shimazaki, Masashi;
Morita, Satoshi

Publication type:

Article

ASP8273 tolerability and antitumor activity in tyrosine kinase inhibitor‐naïve Japanese patients with EGFR mutation‐positive non‐small‐cell lung cancer.

Published in:

Cancer Science, 2018, v. 109, n. 8, p. 2532, doi. 10.1111/cas.13651

By:

Azuma, Koichi;
Nishio, Makoto;
Hayashi, Hidetoshi;
Kiura, Katsuyuki;
Satouchi, Miyako;
Sugawara, Shunichi;
Hida, Toyoaki;
Iwamoto, Yasuo;
Inoue, Akira;
Takeda, Koji;
Ikeda, Satoshi;
Nakagawa, Tomoki;
Takeda, Kentaro;
Asahina, Seitaro;
Komatsu, Kanji;
Morita, Satoshi;
Fukuoka, Masahiro;
Nakagawa, Kazuhiko

Publication type:

Article

Sensitivities to various epidermal growth factor receptor-tyrosine kinase inhibitors of uncommon epidermal growth factor receptor mutations L861Q and S768I: What is the optimal epidermal growth factor receptor-tyrosine kinase inhibitor?

Published in:

Cancer Science, 2016, v. 107, n. 8, p. 1134, doi. 10.1111/cas.12980

By:

Banno, Eri;
Togashi, Yosuke;
Nakamura, Yu;
Chiba, Masato;
Kobayashi, Yoshihisa;
Hayashi, Hidetoshi;
Terashima, Masato;
Velasco, Marco A.;
Sakai, Kazuko;
Fujita, Yoshihiko;
Mitsudomi, Tetsuya;
Nishio, Kazuto

Publication type:

Article

Phase I trial of OTS11101, an anti-angiogenic vaccine targeting vascular endothelial growth factor receptor 1 in solid tumor.

Published in:

Cancer Science, 2013, v. 104, n. 1, p. 98, doi. 10.1111/cas.12034

By:

Hayashi, Hidetoshi;
Kurata, Takayasu;
Fujisaka, Yasuhito;
Kawakami, Hisato;
Tanaka, Kaoru;
Okabe, Takafumi;
Takeda, Masayuki;
Satoh, Taroh;
Yoshida, Koji;
Tsunoda, Takuya;
Arao, Tokuzo;
Nishio, Kazuto;
Nakagawa, Kazuhiko

Publication type:

Article

Synthesis and biological activities in vitro and in vivo of glycosylated human interleukin-1α, neoglyco IL-1α, coupled with N-acetylneuraminyl-galactose.

Published in:

Glycoconjugate Journal, 2003, v. 20, n. 2, p. 119, doi. 10.1023/B:GLYC.0000018586.52083.2a

By:

Ootsubo, Masaaki;
Chiba, Taku;
Kobayashi, Yutaka;
Hayashi, Hidetoshi;
Hayashi, Akiko;
Onozaki, Kikuo

Publication type:

Article

Glycosylated human interleukin-1α, neoglyco IL-1α, coupled with N-acetylneuraminic acid exhibits selective activities in vivo and altered tissue distribution.

Published in:

Glycoconjugate Journal, 2000, v. 17, n. 6, p. 353, doi. 10.1023/A:1007181929405

By:

Sasayama, Satoshi;
Moriya, Kayoko;
Chiba, Taku;
Matsumura, Takayuki;
Hayashi, Hidetoshi;
Hayashi, Akiko;
Onozaki, Kikuo

Publication type:

Article

In vitro biological activities of glycosylated human interleukin-1α, neoglyco IL-1α, coupled with N-acetylneuraminic acid.

Published in:

Glycoconjugate Journal, 1999, v. 16, n. 9, p. 563, doi. 10.1023/A:1007082207188

By:

Moriya, Kayoko;
Chiba, Taku;
Nabeshima, Sachi;
Hayashi, Hidetoshi;
Onozaki, Kikuo

Publication type:

Article

Synthesis of glycosylated human interleukin-1α, neoglyco IL-1α, coupled with N-acetylneuraminic acid.

Published in:

Glycoconjugate Journal, 1999, v. 16, n. 9, p. 499, doi. 10.1023/A:1007017920392

By:

Chiba, Taku;
Moriya, Kayoko;
Nabeshima, Sachi;
Hayashi, Hidetoshi;
Kobayashi, Yutaka;
Sasayama, Satoshi;
Onozaki, Kikuo

Publication type:

Article

Phase 1 study of new formulation of patritumab (U3-1287) Process 2, a fully human anti-HER3 monoclonal antibody in combination with erlotinib in Japanese patients with advanced non-small cell lung cancer.

Published in:

2017

By:

Shimizu, Toshio;
Yonesaka, Kimio;
Hayashi, Hidetoshi;
Iwasa, Tsutomu;
Haratani, Koji;
Yamada, Hironori;
Ohwada, Shoichi;
Kamiyama, Emi;
Nakagawa, Kazuhiko

Publication type:

journal article

Phase I and pharmacokinetic study of gefitinib and S-1 combination therapy for advanced adenocarcinoma of the lung.

Published in:

Cancer Chemotherapy & Pharmacology, 2013, v. 71, n. 4, p. 859, doi. 10.1007/s00280-013-2077-1

By:

Kiyota, Hidemi;
Okamoto, Isamu;
Takeda, Masayuki;
Daga, Haruko;
Naito, Tateaki;
Miyazaki, Masaki;
Okada, Hideaki;
Hayashi, Hidetoshi;
Tanaka, Kaoru;
Terashima, Masaaki;
Azuma, Koichi;
Murakami, Haruyasu;
Takeda, Koji;
Yamamoto, Nobuyuki;
Nakagawa, Kazuhiko

Publication type:

Article

Phase I study of cediranib in combination with cisplatin plus fluoropyrimidine (S-1 or capecitabine) in Japanese patients with previously untreated advanced gastric cancer.

Published in:

Cancer Chemotherapy & Pharmacology, 2012, v. 69, n. 2, p. 439, doi. 10.1007/s00280-011-1723-8

By:

Satoh, Taroh;
Yamada, Yasuhide;
Muro, Kei;
Hayashi, Hidetoshi;
Shimada, Yasuhiro;
Takahari, Daisuke;
Taku, Keisei;
Nakajima, Takako;
Shi, Xiaojin;
Brown, Kathryn;
Boku, Narikazu

Publication type:

Article

TGF-β induces p53/Smads complex formation in the PAI-1 promoter to activate transcription.

Published in:

Scientific Reports, 2016, p. 35483, doi. 10.1038/srep35483

By:

Kawarada, Yuki;
Inoue, Yasumichi;
Kawasaki, Fumihiro;
Fukuura, Keishi;
Sato, Koichi;
Tanaka, Takahito;
Itoh, Yuka;
Hayashi, Hidetoshi

Publication type:

Article