Works by Hatfull, Graham F

Results: 71

Control of Phage Bxb1 Excision by a Novel Recombination Directionality Factor.

Published in:

PLoS Biology, 2006, v. 4, n. 6, p. e186, doi. 10.1371/journal.pbio.0040186

By:

Ghosh, Pallavi;
Wasil, Laura R.;
Hatfull, Graham F.

Publication type:

Article

Stabilization mechanism accommodating genome length variation in evolutionarily related viral capsids.

Published in:

Nature Communications, 2025, v. 16, n. 1, p. 1, doi. 10.1038/s41467-025-58298-0

By:

Podgorski, Jennifer M.;
Podgorski, Joshua;
Abad, Lawrence;
Jacobs-Sera, Deborah;
Freeman, Krista G.;
Brown, Colin;
Hatfull, Graham F.;
Luque, Antoni;
White, Simon J.

Publication type:

Article

A Bioinformatic Ecosystem for Bacteriophage Genomics: PhaMMSeqs, Phamerator, pdm_utils, PhagesDB, DEPhT, and PhamClust.

Published in:

Viruses (1999-4915), 2024, v. 16, n. 8, p. 1278, doi. 10.3390/v16081278

By:

Gauthier, Christian H.;
Hatfull, Graham F.

Publication type:

Article

Unlocking the Potential of 46 New Bacteriophages for Biocontrol of Dickeya Solani.

Published in:

Viruses (1999-4915), 2018, v. 10, n. 11, p. 621, doi. 10.3390/v10110621

By:

Carstens, Alexander B.;
Djurhuus, Amaru M.;
Kot, Witold;
Jacobs-Sera, Deborah;
Hatfull, Graham F.;
Hansen, Lars H.

Publication type:

Article

Unusual prophages in Mycobacterium abscessus genomes and strain variations in phage susceptibilities.

Published in:

PLoS ONE, 2023, v. 18, n. 2, p. 1, doi. 10.1371/journal.pone.0281769

By:

Amarh, Elizabeth D.;
Dedrick, Rebekah M.;
Garlena, Rebecca A.;
Russell, Daniel A.;
Gauthier, Christian H.;
Aull, Haley G.;
Abad, Lawrence;
Jacobs-Sera, Deborah;
Akusobi, Chidiebere;
Rubin, Eric J.;
Hatfull, Graham F.

Publication type:

Article

Transcriptional silencing by the mycobacteriophage L5 repressor.

Published in:

EMBO Journal, 1997, v. 16, n. 19, p. 5914, doi. 10.1093/emboj/16.19.5914

By:

Brown, Kelly L.;
Sarkis, Gary J.;
Wadsworth, Curtis;
Hatfull, Graham F.

Publication type:

Article

Mycobacteriophages: From Petri dish to patient.

Published in:

PLoS Pathogens, 2022, v. 18, n. 7, p. 1, doi. 10.1371/journal.ppat.1010602

By:

Hatfull, Graham F.

Publication type:

Article

Recombineering mycobacteria and their phages.

Published in:

Nature Reviews Microbiology, 2008, v. 6, n. 11, p. 851, doi. 10.1038/nrmicro2014

By:

van Kessel, Julia C.;
Marinelli, Laura J.;
Hatfull, Graham F.

Publication type:

Article

pdm_utils: a SEA-PHAGES MySQL phage database management toolkit.

Published in:

Bioinformatics, 2021, v. 37, n. 16, p. 2464, doi. 10.1093/bioinformatics/btaa983

By:

Mavrich, Travis N;
Gauthier, Christian;
Abad, Lawrence;
Bowman, Charles A;
Cresawn, Steven G;
Hatfull, Graham F

Publication type:

Article

Phage Therapy for Nontuberculous Mycobacteria: Challenges and Opportunities.

Published in:

Pulmonary Therapy, 2023, v. 9, n. 1, p. 91, doi. 10.1007/s41030-022-00210-y

By:

Hatfull, Graham F.

Publication type:

Article

The role of iron in Mycobacterium smegmatis biofilm formation: the exochelin siderophore is essential in limiting iron conditions for biofilm formation but not for planktonic growth.

Published in:

Molecular Microbiology, 2007, v. 66, n. 2, p. 468, doi. 10.1111/j.1365-2958.2007.05935.x

By:

Ojha, Anil;
Hatfull, Graham F.

Publication type:

Article

A peptidoglycan hydrolase motif within the mycobacteriophage TM4 tape measure protein promotes efficient infection of stationary phase cells.

Published in:

Molecular Microbiology, 2006, v. 62, n. 6, p. 1569, doi. 10.1111/j.1365-2958.2006.05473.x

By:

Piuri, Mariana;
Hatfull, Graham F.

Publication type:

Article

Integration and excision by the large serine recombinaseφRv1 integrase.

Published in:

Molecular Microbiology, 2005, v. 55, n. 6, p. 1896, doi. 10.1111/j.1365-2958.2005.04517.x

By:

Bibb, Lori A.;
Hancox, Maria I.;
Hatfull, Graham F.

Publication type:

Article

Mycobacteriophage Bxb1 integrates into the Mycobacterium smegmatis groEL1 gene.

Published in:

Molecular Microbiology, 2003, v. 50, n. 2, p. 463, doi. 10.1046/j.1365-2958.2003.03723.x

By:

Kim, Amy I.;
Ghosh, Pallavi;
Aaron, Michelle A.;
Bibb, Lori A.;
Jain, Shruti;
Hatfull, Graham F.

Publication type:

Article

Integration and excision of the Mycobacterium tuberculosis prophage-like element, φRv1.

Published in:

Molecular Microbiology, 2002, v. 45, n. 6, p. 1515, doi. 10.1046/j.1365-2958.2002.03130.x

By:

Bibb, Lori A.;
Hatfull, Graham F.

Publication type:

Article

Genome organization and characterization of mycobacteriophage Bxb1.

Published in:

Molecular Microbiology, 2000, v. 38, n. 5, p. 955, doi. 10.1046/j.1365-2958.2000.02183.x

By:

Mediavilla, José;
Jain, Shruti;
Kriakov, Jordon;
Ford, Michael E.;
Duda, Robert L.;
Jacobs, William R.;
Hendrix, Roger W.;
Hatfull, Graham F.

Publication type:

Article

Transcriptional regulation and immunity in mycobacteriophage Bxb1.

Published in:

Molecular Microbiology, 2000, v. 38, n. 5, p. 971, doi. 10.1046/j.1365-2958.2000.02184.x

By:

Jain, Shruti;
Hatfull, Graham F.

Publication type:

Article

Identification and characterization of mycobacteriophage L5 excisionase.

Published in:

Molecular Microbiology, 2000, v. 35, n. 2, p. 350, doi. 10.1046/j.1365-2958.2000.01695.x

By:

Lewis, John A;
Hatfull, Graham F

Publication type:

Article

Mycobacteriophage L5 infection of Mycobacterium bovis BCG: implications for phage genetics in the slow- growing mycobacteria.

Published in:

Molecular Microbiology, 1997, v. 26, n. 4, p. 755, doi. 10.1046/j.1365-2958.1997.6111984.x

By:

Fullner, Karia Jean;
Hatfull, Graham F.

Publication type:

Article

Characterization of a Mycobacterium smegmatis gene that confers resistance to phages L5 and D29 when overexpressed.

Published in:

Molecular Microbiology, 1996, v. 21, n. 1, p. 159, doi. 10.1046/j.1365-2958.1996.6291342.x

By:

Barsom, Elizabeth K.;
Hatfull, Graham F.

Publication type:

Article

Transcriptional regulation of repressor synthesis in mycobacteriophage L5.

Published in:

Molecular Microbiology, 1995, v. 17, n. 6, p. 1045, doi. 10.1111/j.1365-2958.1995.mmi_17061045.x

By:

Nesbit, Chadd E.;
Levin, Margaret E.;
Donnelly-Wu, Mary K.;
Hatfull, Graham F.

Publication type:

Article

L5 luciferase reporter mycobacteriophages: a sensitive tool for the detection and assay of live mycobacteria.

Published in:

Molecular Microbiology, 1995, v. 15, n. 6, p. 1055, doi. 10.1111/j.1365-2958.1995.tb02281.x

By:

Sarkis, Gary J.;
Jacobs, William R.;
Hatfull, Graham F.

Publication type:

Article

Control of directionality in integrase-mediated recombination: examination of recombination directionality factors (RDFs) including Xis and Cox proteins.

Published in:

Nucleic Acids Research, 2001, v. 29, n. 11, p. 2205, doi. 10.1093/nar/29.11.2205

By:

Lewis, John A.;
Hatfull, Graham F.

Publication type:

Article

Bacteriophage treatment of disseminated cutaneous Mycobacterium chelonae infection.

Published in:

2022

By:

Little, Jessica S.;
Dedrick, Rebekah M.;
Freeman, Krista G.;
Cristinziano, Madison;
Smith, Bailey E.;
Benson, Constance A.;
Jhaveri, Tulip A.;
Baden, Lindsey R.;
Solomon, Daniel A.;
Hatfull, Graham F.

Publication type:

Case Study

Characterization of mycobacteria and mycobacteriophages isolated from compost at the São Paulo Zoo Park Foundation in Brazil and creation of the new mycobacteriophage Cluster U.

Published in:

BMC Microbiology, 2016, v. 16, p. 1, doi. 10.1186/s12866-016-0734-3

By:

Daltro Lima-Junior, James;
Viana-Niero, Cristina;
Conde Oliveira, Daniel V.;
Esquitini Machado, Gabriel;
da Silva Rabello, Michelle Cristiane;
Martins-Junior, Joaquim;
Farage Martins, Layla;
Digiampietri, Luciano Antonio;
da Silva, Aline Maria;
Setubal, João Carlos;
Russell, Daniel A.;
Jacobs-Sera, Deborah;
Pope, Welkin H.;
Hatfull, Graham F.;
Cardoso Leão, Sylvia

Publication type:

Article

Staphylococci phages display vast genomic diversity and evolutionary relationships.

Published in:

BMC Genomics, 2019, v. 20, n. 1, p. N.PAG, doi. 10.1186/s12864-019-5647-8

By:

Oliveira, Hugo;
Sampaio, Marta;
Melo, Luís D. R.;
Dias, Oscar;
Pope, Welkin H.;
Hatfull, Graham F.;
Azeredo, Joana

Publication type:

Article

Attachment Site Selection and Identity in Bxb1 Serine Integrase-Mediated Site-Specific Recombination

Published in:

PLoS Genetics, 2013, v. 9, n. 5, p. 1, doi. 10.1371/journal.pgen.1003490

By:

Singh, Shweta;
Ghosh, Pallavi;
Hatfull, Graham F.

Publication type:

Article

Exploring the Mycobacteriophage Metaproteome: Phage Genomics as an Educational Platform.

Published in:

PLoS Genetics, 2006, v. 2, n. 6, p. e92, doi. 10.1371/journal.pgen.0020092

By:

Hatfull, Graham F.;
Pedulla, Marisa L.;
Jacobs-Sera, Deborah;
Cichon, Pauline M.;
Foley, Amy;
Ford, Michael E.;
Gonda, Rebecca M.;
Houtz, Jennifer M.;
Hryckowian, Andrew J.;
Kelchner, Vanessa A.;
Namburi, Swathi;
Pajcini, Kostandin V.;
Popovich, Mark G.;
Schleicher, Donald T.;
Simanek, Brian Z.;
Smith, Alexis L.;
Zdanowicz, Gina M.;
Kumar, Vanaja;
Peebles, Craig L.;
Jacobs Jr., William R.

Publication type:

Article

Mycobacteriophages to Treat Tuberculosis: Dream or Delusion?

Published in:

Respiration, 2022, v. 101, n. 1, p. 1, doi. 10.1159/000519870

By:

Diacon, Andreas H.;
Guerrero-Bustamante, Carlos A.;
Rosenkranz, Bernd;
Rubio Pomar, Francisco J.;
Vanker, Naadira;
Hatfull, Graham F.

Publication type:

Article

Genomic and structural analysis of Syn9, a cyanophage infecting marine Prochlorococcus and Synechococcus.

Published in:

Environmental Microbiology, 2007, v. 9, n. 7, p. 1675, doi. 10.1111/j.1462-2920.2007.01285.x

By:

Weigele, Peter R.;
Pope, Welkin H.;
Pedulla, Marisa L.;
Houtz, Jennifer M.;
Smith, Alexis L.;
Conway, James F.;
King, Jonathan;
Hatfull, Graham F.;
Lawrence, Jeffrey G.;
Hendrix, Roger W.

Publication type:

Article

Characterization of mycobacteriophage Adephagia cytotoxic proteins.

Published in:

G3: Genes | Genomes | Genetics, 2024, v. 14, n. 9, p. 1, doi. 10.1093/g3journal/jkae166

By:

Freeman, Krista G;
Lauer, Michael J;
Jiang, Danny;
Roscher, Jennifer;
Sandler, Sterling;
Mercado, Nicholas;
Fryberger, Robert;
Kovalski, Julia;
Lutz, Abigail R;
Hughes, Lee E;
VanDemark, Andrew P;
Hatfull, Graham F

Publication type:

Article

PhaMMseqs: a new pipeline for constructing phage gene phamilies using MMseqs2.

Published in:

G3: Genes | Genomes | Genetics, 2022, v. 12, n. 11, p. 1, doi. 10.1093/g3journal/jkac233

By:

Gauthier, Christian H.;
Cresawn, Steven G.;
Hatfull, Graham F.

Publication type:

Article

Genome analysis of Salmonella enterica serovar Typhimurium bacteriophage L, indicator for StySA (StyLT2III) restriction-modification system action .

Published in:

G3: Genes | Genomes | Genetics, 2021, v. 11, n. 1, p. 1, doi. 10.1093/g3journal/jkaa037

By:

Zaworski, Julie;
McClung, Colleen;
Ruse, Cristian;
Weigele, Peter R.;
Hendrix, RogerW.;
Ko, Ching-Chung;
Edgar, Robert;
Hatfull, Graham F.;
Casjens, Sherwood R.;
Raleigh, Elisabeth A.

Publication type:

Article

Uncoupling of the recombination and topoisomerase activities of the γδ resolvase by a mutation at the crossover point.

Published in:

Nature, 1988, v. 332, n. 6167, p. 861, doi. 10.1038/332861a0

By:

Falvey, Eileen;
Hatfull, Graham F.;
Grindley, Nigel D. F.

Publication type:

Article

Complete genomic sequences of <italic>Propionibacterium freudenreichii</italic> phages from Swiss cheese reveal greater diversity than <italic>Cutibacterium</italic> (formerly <italic>Propionibacterium) acnes</italic> phages.

Published in:

BMC Microbiology, 2018, v. 18, p. 1, doi. 10.1186/s12866-018-1159-y

By:

Cheng, Lucy;
Marinelli, Laura J.;
Grosset, Noël;
Fitz-Gibbon, Sorel T.;
Bowman, Charles A.;
Dang, Brian Q.;
Russell, Daniel A.;
Jacobs-Sera, Deborah;
Shi, Baochen;
Pellegrini, Matteo;
Miller, Jeff F.;
Gautier, Michel;
Hatfull, Graham F.;
Modlin, Robert L.

Publication type:

Article

Expression and evolutionary patterns of mycobacteriophage D29 and its temperate close relatives.

Published in:

BMC Microbiology, 2017, v. 17, p. 1, doi. 10.1186/s12866-017-1131-2

By:

Dedrick, Rebekah M.;
Mavrich, Travis N.;
Ng, Wei L.;
Hatfull, Graham F.

Publication type:

Article

PhagesDB: the actinobacteriophage database.

Published in:

Bioinformatics, 2017, v. 33, n. 5, p. 784, doi. 10.1093/bioinformatics/btw711

By:

Russell, Daniel A.;
Hatfull, Graham F.

Publication type:

Article

Nebulized Bacteriophage in a Patient With Refractory Mycobacterium abscessus Lung Disease.

Published in:

Open Forum Infectious Diseases, 2022, v. 9, n. 7, p. 1, doi. 10.1093/ofid/ofac194

By:

Dedrick, Rebekah M;
Freeman, Krista G;
Nguyen, Jan A;
Bahadirli-Talbott, Asli;
Cardin, Mitchell E;
Cristinziano, Madison;
Smith, Bailey E;
Jeong, Soowan;
Ignatius, Elisa H;
Lin, Cheng Ting;
Cohen, Keira A;
Hatfull, Graham F

Publication type:

Article

The role of supercoiling in mycobacteriophage L5 integrative recombination.

Published in:

Nucleic Acids Research, 1998, v. 26, n. 17, p. 4012, doi. 10.1093/nar/26.17.4012

By:

Peña, Carol E. A.;
Kahlenberg, J. Michelle;
Hatfull, Graham F.

Publication type:

Article

Mycobacteriophages: Windows into Tuberculosis.

Published in:

PLoS Pathogens, 2014, v. 10, n. 3, p. 1, doi. 10.1371/journal.ppat.1003953

By:

Hatfull, Graham F.

Publication type:

Article

Characterization and induction of prophages in human gut-associated Bifidobacterium hosts.

Published in:

Scientific Reports, 2018, v. 8, n. 1, p. 1, doi. 10.1038/s41598-018-31181-3

By:

Mavrich, Travis N.;
Casey, Eoghan;
Oliveira, Joana;
Bottacini, Francesca;
James, Kieran;
Franz, Charles M. A. P.;
Lugli, Gabriele Andrea;
Neve, Horst;
Ventura, Marco;
Hatfull, Graham F.;
Mahony, Jennifer;
van Sinderen, Douwe

Publication type:

Article

Mycobacteriophage Fruitloop gp52 inactivates Wag31 (DivIVA) to prevent heterotypic superinfection.

Published in:

Molecular Microbiology, 2018, v. 108, n. 4, p. 443, doi. 10.1111/mmi.13946

By:

Ko, Ching‐Chung;
Hatfull, Graham F.

Publication type:

Article

Function, expression, specificity, diversity and incompatibility of actinobacteriophage parABS systems.

Published in:

Molecular Microbiology, 2016, v. 101, n. 4, p. 625, doi. 10.1111/mmi.13414

By:

Dedrick, Rebekah M.;
Mavrich, Travis N.;
Ng, Wei L.;
Cervantes Reyes, Juan C.;
Olm, Matthew R.;
Rush, Rachael E.;
Jacobs‐Sera, Deborah;
Russell, Daniel A.;
Hatfull, Graham F.

Publication type:

Article

Functional requirements for bacteriophage growth: gene essentiality and expression in mycobacteriophage Giles.

Published in:

Molecular Microbiology, 2013, v. 88, n. 3, p. 577, doi. 10.1111/mmi.12210

By:

Dedrick, Rebekah M.;
Marinelli, Laura J.;
Newton, Gerald L.;
Pogliano, Kit;
Pogliano, Joseph;
Hatfull, Graham F.

Publication type:

Article

Mycobacteriophage Lysin B is a novel mycolylarabinogalactan esterase.

Published in:

Molecular Microbiology, 2009, v. 73, n. 3, p. 367, doi. 10.1111/j.1365-2958.2009.06775.x

By:

Payne, Kimberly;
Sun, Qingan;
Sacchettini, James;
Hatfull, Graham F.

Publication type:

Article

Growth of Mycobacterium tuberculosis biofilms containing free mycolic acids and harbouring drug-tolerant bacteria.

Published in:

Molecular Microbiology, 2008, v. 69, n. 1, p. 164, doi. 10.1111/j.1365-2958.2008.06274.x

By:

Ojha, Anil K.;
Baughn, Anthony D.;
Sambandan, Dhinakaran;
Tsungda Hsu;
Trivelli, Xavier;
Guerardel, Yann;
Alahari, Anuradha;
Kremer, Laurent;
Jacobs Jr, William R.;
Hatfull, Graham F.

Publication type:

Article

Efficient point mutagenesis in mycobacteria using single-stranded DNA recombineering: characterization of antimycobacterial drug targets.

Published in:

Molecular Microbiology, 2008, v. 67, n. 5, p. 1094, doi. 10.1111/j.1365-2958.2008.06109.x

By:

Van Kessel, Julia C.;
Hatfull, Graham F.

Publication type:

Article

DEPhT: a novel approach for efficient prophage discovery and precise extraction.

Published in:

Nucleic Acids Research, 2022, v. 50, n. 13, p. e75, doi. 10.1093/nar/gkac273

By:

Gauthier, Christian H;
Abad, Lawrence;
Venbakkam, Ananya K;
Malnak, Julia;
Russell, Daniel A;
Hatfull, Graham F

Publication type:

Article

Crossover-site sequence and DNA torsional stress control strand interchanges by the Bxb1 site-specific serine recombinase.

Published in:

Nucleic Acids Research, 2016, v. 44, n. 18, p. 8921, doi. 10.1093/nar/gkw724

By:

Keenholtz, Ross A.;
Grindley, Nigel D. F.;
Hatfull, Graham F.;
Marko, John F.

Publication type:

Article

Recombineering in Mycobacterium tuberculosis.

Published in:

Nature Methods, 2007, v. 4, n. 2, p. 147, doi. 10.1038/nmeth996

By:

van Kessel, Julia C;
Hatfull, Graham F

Publication type:

Article