Works by Hastings, P. J.

Results: 38

Adaptive Amplification and Point Mutation Are Independent Mechanisms: Evidence for Various Stress-Inducible Mutation Mechanisms.

Published in:

PLoS Biology, 2004, v. 2, n. 12, p. 2220, doi. 10.1371/journal.pbio.0020399

By:

Hastings, P. J.;
Slack, Andrew;
Petrosino, Joseph F.;
Rosenberg, Susan M.

Publication type:

Article

Adaptive Amplification and Point Mutation Are Independent Mechanisms: Evidence for Various Stress-Inducible Mutation Mechanisms.

Published in:

PLoS Biology, 2004, v. 2, n. 11, p. 1, doi. 10.1371/journal.pbio.0020399

By:

Hastings, P. J;
Slack, Andrew;
Petrosino, Joseph F;
Rosenberg, Susan M

Publication type:

Article

Oxygen and RNA in stress-induced mutation.

Published in:

Current Genetics, 2018, v. 64, n. 4, p. 769, doi. 10.1007/s00294-017-0801-9

By:

Correa, Raul;
Thornton, Philip C.;
Hastings, P. J.;
Rosenberg, Susan M.

Publication type:

Article

Yeast EndoG prevents genome instability by degrading extranuclear DNA species.

Published in:

Nature Communications, 2024, v. 15, n. 1, p. 1, doi. 10.1038/s41467-024-52147-2

By:

Yu, Yang;
Wang, Xin;
Fox, Jordan;
Yu, Ruofan;
Thakre, Pilendra;
McCauley, Brenna;
Nikoloutsos, Nicolas;
Li, Qian;
Hastings, P. J.;
Dang, Weiwei;
Chen, Kaifu;
Ira, Grzegorz

Publication type:

Article

Recombination in the eukaryotic nucleus.

Published in:

BioEssays, 1988, v. 9, n. 2/3, p. 61, doi. 10.1002/bies.950090206

By:

Hastings, P. J.

Publication type:

Article

Genomes: Worming into genetic instability.

Published in:

Nature, 2004, v. 430, n. 7000, p. 625, doi. 10.1038/430625a

By:

Rosenberg, Susan M.;
Hastings, P. J.

Publication type:

Article

GENE CONVERSION AND INTRAGENIC RECOMBINATION AT AT THE SUP6 LOCUS AND THE SURROUNDING REGION IN SACCHAROMYCES CEREVISIAE.

Published in:

Genetics, 1976, v. 84, n. 4, p. 697

By:

DICAPRIO, LAURA;
HASTINGS, P. J.

Publication type:

Article

PRE-MEIOTIC DNA SYNTHESIS AND RECOMBINATION IN CHLAMYDOMONAS REINHARDI.

Published in:

Genetics, 1973, v. 73, n. 1, p. 29

By:

CHIU, s. M.;
HASTINGS, P. J.

Publication type:

Article

A possible source of primary nucleotide chain breaks in recombinant structures in eukaryotes.

Published in:

Genetics Research, 1972, v. 20, n. 2, p. 253, doi. 10.1017/S0016672300013756

By:

Hastings, P. J.

Publication type:

Article

The analysis of genetic recombination on the polaron hybrid DNA model.

Published in:

Genetics Research, 1965, v. 6, n. 1, p. 27, doi. 10.1017/S0016672300003955

By:

Whitehouse, H. L. K.;
Hastings, P. J.

Publication type:

Article

A role for topoisomerase III in a recombination pathway alternative to RuvABC.

Published in:

Molecular Microbiology, 2005, v. 58, n. 1, p. 80, doi. 10.1111/j.1365-2958.2005.04812.x

By:

Lopez, Christopher R.;
Yang, Shirley;
Deibler, Richard W.;
Ray, Starlight A.;
Pennington, Jeanine M.;
DiGate, Russell J.;
Hastings, P. J.;
Rosenberg, Susan M.;
Zechiedrich, E. Lynn

Publication type:

Article

Hypoxia and miscoupling between reduced energy efficiency and signaling to cell proliferation drive cancer to grow increasingly faster.

Published in:

Journal of Molecular Cell Biology, 2012, v. 4, n. 3, p. 174, doi. 10.1093/jmcb/mjs017

By:

Cui, Juan;
Mao, Xizeng;
Olman, Victor;
Hastings, P. J.;
Xu, Ying

Publication type:

Article

Inverted genomic segments and complex triplication rearrangements are mediated by inverted repeats in the human genome.

Published in:

Nature Genetics, 2011, v. 43, n. 11, p. 1074, doi. 10.1038/ng.944

By:

Carvalho, Claudia M B;
Ramocki, Melissa B;
Pehlivan, Davut;
Franco, Luis M;
Gonzaga-Jauregui, Claudia;
Fang, Ping;
McCall, Alanna;
Pivnick, Eniko Karman;
Hines-Dowell, Stacy;
Seaver, Laurie H;
Friehling, Linda;
Lee, Sansan;
Smith, Rosemarie;
del Gaudio, Daniela;
Withers, Marjorie;
Liu, Pengfei;
Cheung, Sau Wai;
Belmont, John W;
Zoghbi, Huda Y;
Hastings, P J

Publication type:

Article

Global Chromosomal Structural Instability in a Subpopulation of Starving Escherichia coli Cells.

Published in:

PLoS Genetics, 2011, v. 7, n. 8, p. 1, doi. 10.1371/journal.pgen.1002223

By:

Lin, Dongxu;
Gibson, Ian B.;
Moore, Jessica M.;
Thornton, P. C.;
Leal, Suzanne M.;
Hastings, P. J.

Publication type:

Article

Role of RecA and the SOS Response in Thymineless Death in Escherichia coli.

Published in:

PLoS Genetics, 2010, v. 6, n. 3, p. 1, doi. 10.1371/journal.pgen.1000865

By:

Fonville, Natalie C.;
Bates, David;
Hastings, P. J.;
Hanawalt, Philip C.;
Rosenberg, Susan M.

Publication type:

Article

A Microhomology-Mediated Break-Induced Replication Model for the Origin of Human Copy Number Variation.

Published in:

PLoS Genetics, 2009, v. 5, n. 1, p. 1, doi. 10.1371/journal.pgen.1000327

By:

Hastings, P. J.;
Ira, Grzegorz;
Lupski, James R.

Publication type:

Article

Mutability and Importance of a Hypermutable Cell Subpopulation that Produces Stress-Induced Mutants in Escherichia coli.

Published in:

PLoS Genetics, 2008, v. 4, n. 10, p. 1, doi. 10.1371/journal.pgen.1000208

By:

Gonzalez, Caleb;
Hadany, Lilach;
Ponder, Rebecca G.;
Price, Mellanie;
Hastings, P. J.;
Rosenberg, Susan M.

Publication type:

Article

On the Mechanism of Gene Amplification<br /> Induced under Stress in Escherichia coli.

Published in:

PLoS Genetics, 2006, v. 2, n. 4, p. e48, doi. 10.1371/journal.pgen.0020048

By:

Slack, Andrew;
Thornton, P. C.;
Magner, Daniel B.;
Rosenberg, Susan M.;
Hastings, P. J.

Publication type:

Article

Spontaneous mutation by mutagenic repair of spontaneous lesions in DNA.

Published in:

Nature, 1976, v. 264, n. 5588, p. 719, doi. 10.1038/264719a0

By:

Hastings, P. J.;
Quah, Siew-Keen;
von Borstel, R. C.

Publication type:

Article

Replicative mechanisms for CNV formation are error prone.

Published in:

Nature Genetics, 2013, v. 45, n. 11, p. 1319, doi. 10.1038/ng.2768

By:

Carvalho, Claudia M B;
Pehlivan, Davut;
Ramocki, Melissa B;
Fang, Ping;
Alleva, Benjamin;
Franco, Luis M;
Belmont, John W;
Hastings, P J;
Lupski, James R

Publication type:

Article

The multiple de novo copy number variant (MdnCNV) phenomenon presents with peri-zygotic DNA mutational signatures and multilocus pathogenic variation.

Published in:

Genome Medicine, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13073-022-01123-w

By:

Du, Haowei;
Jolly, Angad;
Grochowski, Christopher M.;
Yuan, Bo;
Dawood, Moez;
Jhangiani, Shalini N.;
Li, He;
Muzny, Donna;
Fatih, Jawid M.;
Coban-Akdemir, Zeynep;
Carlin, Mary Esther;
Scheuerle, Angela E.;
Witzl, Karin;
Posey, Jennifer E.;
Pendleton, Matthew;
Harrington, Eoghan;
Juul, Sissel;
Hastings, P. J.;
Bi, Weimin;
Gibbs, Richard A.

Publication type:

Article

A Polaron Model of Genetic Recombination by the Formation of Hybrid Deoxyribonucleic Acid.

Published in:

Nature, 1964, v. 201, n. 4923, p. 1052, doi. 10.1038/2011052b0

By:

HASTINGS, P. J.;
WHITEHOUSE, H. L. K.

Publication type:

Article

Mechanisms of change in gene copy number.

Published in:

2009

By:

Hastings, P. J.;
Lupski, James R.;
Rosenberg, Susan M.;
Ira, Grzegorz

Publication type:

journal article

Stress-induced mutation via DNA breaks in Escherichia coli: A molecular mechanism with implications for evolution and medicine.

Published in:

BioEssays, 2012, v. 34, n. 10, p. 885, doi. 10.1002/bies.201200050

By:

Rosenberg, Susan M.;
Shee, Chandan;
Frisch, Ryan L.;
Hastings, P. J.

Publication type:

Article

The σ<sup>E</sup> stress response is required for stress-induced mutation and amplification in Escherichia coli.

Published in:

Molecular Microbiology, 2010, v. 77, n. 2, p. 415, doi. 10.1111/j.1365-2958.2010.07213.x

By:

Gibson, Janet L.;
Lombardo, Mary-Jane;
Thornton, Philip C.;
Hu, Kenneth H.;
Galhardo, Rodrigo S.;
Beadle, Bernadette;
Habib, Anand;
Magner, Daniel B.;
Frost, Laura S.;
Herman, Christophe;
Hastings, P. J.;
Rosenberg, Susan M.

Publication type:

Article

Corrigendum: R-loops and nicks initiate DNA breakage and genome instability in non-growing Escherichia coli.

Published in:

Nature Communications, 2014, v. 5, n. 1, p. 2762, doi. 10.1038/ncomms3762

By:

Wimberly, Hallie;
Shee, Chandan;
Thornton, P. C.;
Sivaramakrishnan, Priya;
Rosenberg, Susan M.;
Hastings, P. J.

Publication type:

Article

R-loops and nicks initiate DNA breakage and genome instability in non-growing Escherichia coli.

Published in:

Nature Communications, 2013, v. 4, n. 7, p. 2115, doi. 10.1038/ncomms3115

By:

Wimberly, Hallie;
Shee, Chandan;
Thornton, P. C.;
Sivaramakrishnan, Priya;
Rosenberg, Susan M.;
Hastings, P. J.

Publication type:

Article

RPA and Rad27 limit templated and inverted insertions at DNA breaks.

Published in:

Nucleic Acids Research, 2025, v. 53, n. 1, p. 1, doi. 10.1093/nar/gkae1159

By:

Yu, Yang;
Wang, Xin;
Fox, Jordan;
Li, Qian;
Hastings, P J;
Chen, Kaifu;
Ira, Grzegorz

Publication type:

Article

An ultra-dense library resource for rapid deconvolution of mutations that cause phenotypes in Escherichia coli.

Published in:

Nucleic Acids Research, 2016, v. 44, n. 5, p. 1, doi. 10.1093/nar/gkv1131

By:

Nehring, Ralf B.;
Gu, Franklin;
Hsin-Yu Lin;
Gibson, Janet L.;
Blythe, Martin J.;
Wilson, Ray;
Bravo Núñez, María Angélica;
Hastings, P. J.;
Louis, Edward J.;
Frisch, Ryan L.;
Hu, James C.;
Rosenberg, Susan M.

Publication type:

Article

Analysis of the Mechanism for Reversion of a Disrupted Gene.

Published in:

Genetics, 1988, v. 119, n. 2, p. 237

By:

Schiestl, Robert H.;
Igarashi, Sack;
Hastings, P. J.

Publication type:

Article

THE ORIGIN OF SPONTANEOUS MUTATION IN SACCHAROMYCES CEREVISIAE.

Published in:

Genetics, 1980, v. 96, n. 4, p. 819

By:

SIEW-KEEN QUAH;
VON BORSTEL, R. C.;
HASTINGS, P. J.

Publication type:

Article

Competition of Escherichia coli DNA Polymerases I, II and III with DNA Pol IV in Stressed Cells.

Published in:

PLoS ONE, 2010, v. 5, n. 5, p. 1, doi. 10.1371/journal.pone.0010862

By:

Hastings, P. J.;
Hersh, Megan N.;
Thornton, P. C.;
Fonville, Natalie C.;
Slack, Andrew;
Frisch, Ryan L.;
Ray, Mellanie P.;
Harris, Reuben S.;
Leal, Suzanne M.;
Rosenberg, Susan M.

Publication type:

Article

Roles of Nucleoid-Associated Proteins in Stress-Induced Mutagenic Break Repair in Starving Escherichia coli.

Published in:

Genetics, 2015, v. 201, n. 4, p. 1349, doi. 10.1534/genetics.115.178970

By:

Moore, Jessica M.;
Magnan, David;
Mojica, Ana K.;
Núñez, María Angélica Bravo;
Bates, David;
Rosenberg, Susan M.;
Hastings, P. J.

Publication type:

Article

Pathways of Resistance to Thymineless Death in Escherichia coli and the Function of UvrD.

Published in:

Genetics, 2011, v. 189, n. 1, p. 23, doi. 10.1534/genetics.111.130161

By:

Fonville, Natalie C.;
Vaksman, Zalman;
DeNapoli, Jessica;
Hastings, P. J.;
Rosenberg, Susan M.

Publication type:

Article

DinB Upregulation Is the Sole Role of the SOS Response in Stress-Induced Mutagenesis in Escherichia coli.

Published in:

Genetics, 2009, v. 182, n. 1, p. 55, doi. 10.1534/genetics.109.100735

By:

Galhardo, Rodrigo S.;
Do, Robert;
Yamada, Masami;
Friedberg, Errol C.;
Hastings, P. J.;
Nohmi, Takehiko;
Rosenberg, Susan M.

Publication type:

Article

Mutation as a Stress Response and the Regulation of Evolvability.

Published in:

Critical Reviews in Biochemistry & Molecular Biology, 2007, v. 42, n. 5, p. 399, doi. 10.1080/10409230701648502

By:

Galhardo, Rodrigo S.;
Hastings, P. J.;
Rosenberg, Susan M.

Publication type:

Article

Adaptive Amplification.

Published in:

Critical Reviews in Biochemistry & Molecular Biology, 2007, v. 42, n. 4, p. 271, doi. 10.1080/10409230701507757

By:

Hastings, P. J.

Publication type:

Article

Persistent damaged bases in DNA allow mutagenic break repair in Escherichia coli.

Published in:

PLoS Genetics, 2017, v. 13, n. 7, p. 1, doi. 10.1371/journal.pgen.1006733

By:

Moore, Jessica M.;
Correa, Raul;
Rosenberg, Susan M.;
Hastings, P. J.

Publication type:

Article