Works by Hastie, Nicholas D.

Results: 44

Defective mitosis due to a mutation in the gene for a fission yeast 26S protease subunit.

Published in:

Nature, 1993, v. 366, n. 6453, p. 355, doi. 10.1038/366355a0

By:

Gordon, Colin;
McGurk, Gordon;
Dillon, Patrick;
Rosen, Craig;
Hastie, Nicholas D.

Publication type:

Article

Faithful expression of a tagged Fugu WT1 protein from a genomic transgene in zebrafish: efficient splicing of pufferfish genes in zebrafish but not mice.

Published in:

Nucleic Acids Research, 2003, v. 31, n. 11, p. 2795, doi. 10.1093/nar/gkg383

By:

Miles, Colin G.;
Rankin, Lesley;
Smith, Shirley I.;
Niksic, Martina;
Elgar, Greg;
Hastie, Nicholas D.

Publication type:

Article

Genome-Wide Association Study (GWAS) of plasma Aß levels in the dalmatian islands of Vis and korcula

Published in:

2009

By:

Allen, Mariet;
Ansari, Morad;
Younkin, Linda;
Hayward, Caroline;
Vitart, Veronique;
Campbell, Susan;
Huffman, Jennifer;
Morgan, Joanne;
Polasek, Ozren;
Hastie, Nicholas D.;
Rudan 3, Igor;
Campbell, Harry;
Younkin, Steven G.;
Wright, Alan

Publication type:

Abstract

WT1 and kidney failure.

Published in:

Journal of Pathology, 2003, v. 200, n. 5, p. 667

By:

Aswin L Menke;
Annemieke IJpenberg;
Stewart Fleming;
Allyson Ross;
Claire N Medine;
Charles E Patek;
Lee Spraggon;
Jeremy Hughes;
Alan R Clarke;
Nicholas D Hastie

Publication type:

Article

Increased Expression of the 5-HT Transporter Confers a Low-Anxiety Phenotype Linked to Decreased 5-HT Transmission.

Published in:

Journal of Neuroscience, 2006, v. 26, n. 35, p. 8955, doi. 10.1523/JNEUROSCI.5356-05.2006

By:

Jennings, Katie A.;
Loder, Merewyn K.;
Sheward, W. John;
Qi Pei;
Deacon, Robert M. J.;
Benson, Matthew A.;
Olverman, Henry J.;
Hastie, Nicholas D.;
Harmar, Anthony J.;
Sanbing Shen;
Sharp, Trevor

Publication type:

Article

Regulation of the Wilms' tumor gene during spermatogenesis.

Published in:

Developmental Dynamics, 1996, v. 207, n. 4, p. 372, doi. 10.1002/(SICI)1097-0177(199612)207:4<372::AID-AJA2>3.0.CO;2-E

By:

del Rio-Tsonis, Katia;
Covarrubias, Luis;
Kent, Jill;
Hastie, Nicholas D.;
Tsonis, Panagiotis A.

Publication type:

Article

Effects of CreER<sup>T2</sup>, 4-OH Tamoxifen, and Gender on CFU-F Assays.

Published in:

PLoS ONE, 2016, v. 11, n. 2, p. 1, doi. 10.1371/journal.pone.0148105

By:

McHaffie, Sophie L.;
Hastie, Nicholas D.;
Chau, You-Ying

Publication type:

Article

Contribution of consanguinuity to polygenic and multifactorial diseases.

Published in:

2006

By:

Rudan, Igor;
Campbell, Harry;
Carothers, Andrew D.;
Hastie, Nicholas D.;
Wright, Alan F.

Publication type:

Letter

Molecular determinants of WNT9b responsiveness in nephron progenitor cells.

Published in:

PLoS ONE, 2019, v. 14, n. 4, p. 1, doi. 10.1371/journal.pone.0215139

By:

Dickinson, Kyle K.;
Hammond, Leah C.;
Karner, Courtney M.;
Hastie, Nicholas D.;
Carroll, Thomas J.;
Goodyer, Paul

Publication type:

Article

Correction: Pedigree- and SNP-Associated Genetics and Recent Environment are the Major Contributors to Anthropometric and Cardiometabolic Trait Variation.

Published in:

2017

By:

Xia, Charley;
Amador, Carmen;
Huffman, Jennifer;
Trochet, Holly;
Campbell, Archie;
Porteous, David;
Scotland, Generation;
Hastie, Nicholas D.;
Hayward, Caroline;
Vitart, Veronique;
Navarro, Pau;
Haley, Chris S.

Publication type:

Correction Notice

Exome Sequencing to Detect Rare Variants Associated With General Cognitive Ability: A Pilot Study.

Published in:

Twin Research & Human Genetics, 2015, v. 18, n. 2, p. 117, doi. 10.1017/thg.2015.10

By:

Luciano, Michelle;
Svinti, Victoria;
Campbell, Archie;
Marioni, Riccardo E.;
Hayward, Caroline;
Wright, Alan F.;
Taylor, Martin S.;
Porteous, David J.;
Thomson, Pippa;
Prendergast, James G.D.;
Hastie, Nicholas D.;
Farrington, Susan M.;
Scotland, Generation;
Dunlop, Malcolm G.;
Deary, Ian J.

Publication type:

Article

Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants.

Published in:

Genome Medicine, 2017, v. 9, p. 1, doi. 10.1186/s13073-017-0414-4

By:

Nagy, Reka;
Boutin, Thibaud S.;
Marten, Jonathan;
Huffman, Jennifer E.;
Kerr, Shona M.;
Campbell, Archie;
Evenden, Louise;
Gibson, Jude;
Amador, Carmen;
Howard, David M.;
Navarro, Pau;
Morris, Andrew;
Deary, Ian J.;
Hocking, Lynne J.;
Padmanabhan, Sandosh;
Smith, Blair H.;
Joshi, Peter;
Wilson, James F.;
Hastie, Nicholas D.;
Wright, Alan F.

Publication type:

Article

Plasma protease inhibitors in mouse and man: divergence within the reactive centre regions.

Published in:

Nature, 1984, v. 311, n. 5982, p. 175, doi. 10.1038/311175a0

By:

Hill, Robert E.;
Shaw, Phillip H.;
Boyd, Patricia A.;
Baumann, Heinz;
Hastie, Nicholas D.

Publication type:

Article

Expression of the wilms' tumor gene WT1 in human malignant mesothelioma cell lines and relationship to platelet-derived growth factor A and insulin-like growth factor 2 expression.

Published in:

Genes, Chromosomes & Cancer, 1995, v. 12, n. 2, p. 87, doi. 10.1002/gcc.2870120203

By:

Langerak, Anthonie W.;
Williamson, Kathleen A.;
Miyagawa, Kiyoshi;
Hagemeijer, Anne;
Versnel, Marjan A.;
Hastie, Nicholas D.

Publication type:

Article

The Wilms' tumour suppressor Wt1 is a major regulator of tumour angiogenesis and progression.

Published in:

Nature Communications, 2014, v. 5, n. 12, p. 5852, doi. 10.1038/ncomms6852

By:

Wagner, Kay-Dietrich;
Cherfils-Vicini, Julien;
Hosen, Naoki;
Hohenstein, Peter;
Gilson, Eric;
Hastie, Nicholas D.;
Michiels, Jean-François;
Wagner, Nicole

Publication type:

Article

Genome-wide analysis of epistasis in body mass index using multiple human populations.

Published in:

European Journal of Human Genetics, 2012, v. 20, n. 8, p. 857, doi. 10.1038/ejhg.2012.17

By:

Wei, Wen-Hua;
Hemani, Gib;
Gyenesei, Attila;
Vitart, Veronique;
Navarro, Pau;
Hayward, Caroline;
Cabrera, Claudia P;
Huffman, Jennifer E;
Knott, Sara A;
Hicks, Andrew A;
Rudan, Igor;
Pramstaller, Peter P;
Wild, Sarah H;
Wilson, James F;
Campbell, Harry;
Hastie, Nicholas D;
Wright, Alan F;
Haley, Chris S

Publication type:

Article

WT1 expression in breast cancer disrupts the epithelial/mesenchymal balance of tumour cells and correlates with the metabolic response to docetaxel.

Published in:

Scientific Reports, 2017, p. 45255, doi. 10.1038/srep45255

By:

Artibani, Mara;
Sims, Andrew H.;
Slight, Joan;
Aitken, Stuart;
Thornburn, Anna;
Muir, Morwenna;
Brunton, Valerie G.;
Del-Pozo, Jorge;
Morrison, Linda R.;
Katz, Elad;
Hastie, Nicholas D.;
Hohenstein, Peter

Publication type:

Article

Homozygous loss-of-function variants in European cosmopolitan and isolate populations.

Published in:

Human Molecular Genetics, 2015, v. 24, n. 19, p. 5464, doi. 10.1093/hmg/ddv272

By:

Kaiser, Vera B.;
Svinti, Victoria;
Prendergast, James G.;
You-Ying Chau;
Campbell, Archie;
Patarcic, Inga;
Barroso, Inês;
Joshi, Peter K.;
Hastie, Nicholas D.;
Miljkovic, Ana;
Taylor, Martin S.;
Scotland, Generation;
Enroth, Stefan;
Memari, Yasin;
Kolb-Kokocinski, Anja;
Wright, Alan F.;
Gyllensten, Ulf;
Durbin, Richard;
Rudan, Igor;
Campbell, Harry

Publication type:

Article

WT1 regulates the expression of inhibitory chemokines during heart development.

Published in:

Human Molecular Genetics, 2013, v. 22, n. 25, p. 5083, doi. 10.1093/hmg/ddt358

By:

Velecela, Victor;
Lettice, Laura A.;
Chau, You-Ying;
Slight, Joan;
Berry, Rachel L.;
Thornburn, Anna;
Gunst, Quinn D.;
van den Hoff, Maurice;
Reina, Manuel;
Martínez, Fernando O.;
Hastie, Nicholas D.;
Martínez-Estrada, Ofelia M.

Publication type:

Article

Polymorphisms in B3GAT1, SLC9A9 and MGAT5 are associated with variation within the human plasma N-glycome of 3533 European adults.

Published in:

Human Molecular Genetics, 2011, v. 20, n. 24, p. 5000, doi. 10.1093/hmg/ddr414

By:

Huffman, Jennifer E.;
Knežević, Ana;
Vitart, Veronique;
Kattla, Jayesh;
Adamczyk, Barbara;
Novokmet, Mislav;
Igl, Wilmar;
Pučić, Maja;
Zgaga, Lina;
Johannson, Åsa;
Redžić, Irma;
Gornik, Olga;
Zemunik, Tatijana;
Polašek, Ozren;
Kolčić, Ivana;
Pehlić, Marina;
Koeleman, Carolien A.M.;
Campbell, Susan;
Wild, Sarah H.;
Hastie, Nicholas D.

Publication type:

Article

Esrrg functions in early branch generation of the ureteric bud and is essential for normal development of the renal papilla.

Published in:

Human Molecular Genetics, 2011, v. 20, n. 5, p. 917, doi. 10.1093/hmg/ddq530

By:

Berry, Rachel;
Harewood, Louise;
Pei, Liming;
Fisher, Malcolm;
Brownstein, David;
Ross, Allyson;
Alaynick, William A.;
Moss, Julie;
Hastie, Nicholas D.;
Hohenstein, Peter;
Davies, Jamie A.;
Evans, Ronald M.;
FitzPatrick, David R.

Publication type:

Article

New loci associated with central cornea thickness include COL5A1, AKAP13 and AVGR8.

Published in:

Human Molecular Genetics, 2010, v. 19, n. 21, p. 4304, doi. 10.1093/hmg/ddq349

By:

Vitart, Veronique;
Benčić, Goran;
Hayward, Caroline;
Škunca Herman, Jelena;
Huffman, Jennifer;
Campbell, Susan;
Bućan, Kajo;
Navarro, Pau;
Gunjaca, Grgo;
Marin, Josipa;
Zgaga, Lina;
Kolčić, Ivana;
Polašek, Ozren;
Kirin, Mirna;
Hastie, Nicholas D.;
Wilson, James F.;
Rudan, Igor;
Campbell, Harry;
Vatavuk, Zoran;
Fleck, Brian

Publication type:

Article

Effects of genome-wide heterozygosity on a range of biomedically relevant human quantitative traits.

Published in:

Human Molecular Genetics, 2007, v. 16, n. 2, p. 233, doi. 10.1093/hmg/ddl473

By:

Campbell, Harry;
Carothers, Andrew D.;
Rudan, Igor;
Hayward, Caroline;
Biloglav, Zrinka;
Barac, Lovorka;
Pericic, Marijana;
Janicijevic, Branka;
Smolej-Narancic, Nina;
Polasek, Ozren;
Kolcic, Ivana;
Weber, James L.;
Hastie, Nicholas D.;
Rudan, Pavao;
Wright, Alan F.

Publication type:

Article

Local Exome Sequences Facilitate Imputation of Less Common Variants and Increase Power of Genome Wide Association Studies.

Published in:

PLoS ONE, 2013, v. 8, n. 7, p. 1, doi. 10.1371/journal.pone.0068604

By:

Joshi, Peter K.;
Prendergast, James;
Fraser, Ross M.;
Huffman, Jennifer E.;
Vitart, Veronique;
Hayward, Caroline;
McQuillan, Ruth;
Glodzik, Dominik;
Polašek, Ozren;
Hastie, Nicholas D.;
Rudan, Igor;
Campbell, Harry;
Wright, Alan F.;
Haley, Chris S.;
Wilson, James F.;
Navarro, Pau

Publication type:

Article

A ‘complexity’ of urate transporters.

Published in:

Kidney International, 2010, v. 78, n. 5, p. 446, doi. 10.1038/ki.2010.206

By:

Wright, Alan F.;
Rudan, Igor;
Hastie, Nicholas D.;
Campbell, Harry

Publication type:

Article

A 'complexity' of urate transporters.

Published in:

2010

By:

Wright AF;
Rudan I;
Hastie ND;
Campbell H;
Wright, Alan F;
Rudan, Igor;
Hastie, Nicholas D;
Campbell, Harry

Publication type:

journal article

The Wilms’ tumor suppressor WT1: Approaches to gene function.

Published in:

Kidney International, 1998, v. 53, n. 6, p. 1512, doi. 10.1046/j.1523-1755.1998.00935.x

By:

Menke, Aswin;
McInnes, Lesley;
Hastie, Nicholas D.;
Schedl, Andreas

Publication type:

Article

Pedigree- and SNP-Associated Genetics and Recent Environment are the Major Contributors to Anthropometric and Cardiometabolic Trait Variation.

Published in:

PLoS Genetics, 2016, v. 12, n. 2, p. 1, doi. 10.1371/journal.pgen.1005804

By:

Xia, Charley;
Amador, Carmen;
Huffman, Jennifer;
Trochet, Holly;
Campbell, Archie;
Porteous, David;
null, null;
Hastie, Nicholas D.;
Hayward, Caroline;
Vitart, Veronique;
Navarro, Pau;
Haley, Chris S.

Publication type:

Article

Genetic comparison of a Croatian isolate and CEPH European founders.

Published in:

Genetic Epidemiology, 2010, v. 34, n. 2, p. 140, doi. 10.1002/gepi.20443

By:

Navarro, Pau;
Vitart, Véronique;
Hayward, Caroline;
Tenesa, Albert;
Zgaga, Lina;
Juricic, Danica;
Polasek, Ozren;
Hastie, Nicholas D.;
Rudan, Igor;
Campbell, Harry;
Wright, Alan F.;
Haley, Chris S.;
Knott, Sara A.

Publication type:

Article

A Quantitative Trait Locus for SBP Maps Near KCNB1 and PTGIS in a Population Isolate.

Published in:

American Journal of Hypertension, 2009, v. 22, n. 6, p. 663, doi. 10.1038/ajh.2009.46

By:

Barbalić, Maja;
Narančić, Nina Smolej;
Škarić-Jurić, Tatjana;
Salihović, Marijana Peričić;
Klarić, Irena Martinović;
Lauc, Lovorka Barać;
Janićijević, Branka;
Farrall, Martin;
Rudan, Igor;
Campbell, Harry;
Wright, Alan F.;
Hastie, Nicholas D.;
Rudan, Pavao

Publication type:

Article

Wilms Tumor 1b defines a wound-specific sheath cell subpopulation associated with notochord repair.

Published in:

eLife, 2018, p. 1, doi. 10.7554/eLife.30657

By:

Lopez-Baez, Juan Carlos;
Simpson, Daniel J.;
Forero, Laura LLeras;
Zhiqiang Zeng;
Brunsdon, Hannah;
Salzano, Angela;
Brombin, Alessandro;
Wyatt, Cameron;
Rybski, Witold;
Huitema, Leonie F. A.;
Dale, Rodney M.;
Koichi Kawakami;
Englert, Christoph;
Chandra, Tamir;
Schulte-Merker, Stefan;
Hastie, Nicholas D.;
Patton, E. Elizabeth

Publication type:

Article

The many facets of the Wilms' tumour gene, WT1.

Published in:

Human Molecular Genetics, 2006, v. 15, n. 2, p. r196, doi. 10.1093/hmg/ddl196

By:

Hohenstein, Peter;
Hastie, Nicholas D.

Publication type:

Article

The many facets of the Wilms' tumour gene, WT1.

Published in:

Human Molecular Genetics, 2006, v. 15, n. suppl_2, p. R196, doi. 10.1093/hmg/ddl196

By:

Hohenstein, Peter;
Hastie, Nicholas D.

Publication type:

Article

The Wilms' tumour protein (WT1) shuttles between nucleus and cytoplasm and is present in functional polysomes.

Published in:

Human Molecular Genetics, 2004, v. 13, n. 4, p. 463

By:

Niksic, Martina;
Slight, Joan;
Sanford, Jeremy R.;
Caceres, Javier F.;
Hastie, Nicholas D.

Publication type:

Article

Mutation in a short-chain collagen gene, CTRP5, results in extracellular deposit formation in late-onset retinal degeneration: a genetic model for age-related macular degeneration.

Published in:

Human Molecular Genetics, 2003, v. 12, n. 20, p. 2657, doi. 10.1093/hmg/ddg289

By:

Hayward, Caroline;
Shu, Xinhua;
Cideciyan, Artur V.;
Lennon, Alan;
Barran, Perdita;
Zareparsi, Sepideh;
Sawyer, Lindsay;
Hendry, Grace;
Dhillon, Baljean;
Milam, Ann H.;
Luthert, Philip J.;
Swaroop, Anand;
Hastie, Nicholas D.;
Jacobson, Samuel G.;
Wright, Alan F.

Publication type:

Article

Murine Denys–Drash syndrome: evidence of podocyte de-differentiation and systemic mediation of glomerulosclerosis.

Published in:

Human Molecular Genetics, 2003, v. 12, n. 18, p. 2379, doi. 10.1093/hmg/ddg240

By:

Patek, Charles E.;
Fleming, Stewart;
Miles, Colin G.;
Bellamy, Christopher O.;
Ladomery, Michael;
Spraggon, Lee;
Mullins, John;
Hastie, Nicholas D.;
Hooper, Martin L.

Publication type:

Article

Transcriptome analysis of human autosomal trisomy.

Published in:

Human Molecular Genetics, 2002, v. 11, n. 26, p. 3249, doi. 10.1093/hmg/11.26.3249

By:

FitzPatrick, David R.;
Ramsay, Jacqueline;
McGill, Niolette I.;
Shade, Mary;
Carothers, Andrew D.;
Hastie, Nicholas D.

Publication type:

Article

WT1 is a key regulator of podocyte function: reduced expression levels cause crescentic glomerulonephritis and mesangial sclerosis.

Published in:

Human Molecular Genetics, 2002, v. 11, n. 6, p. 651, doi. 10.1093/hmg/11.6.651

By:

Guo, Jian-Kan;
Menke, Aswin L.;
Gubler, Marie-Claire;
Clarke, Alan R.;
Harrison, David;
Hammes, Annette;
Hastie, Nicholas D.;
Schedl, Andreas

Publication type:

Article

Did nucleotides or amino acids drive evolutionary conservation of the WT1 ± KTS alternative splice?

Published in:

Human Molecular Genetics, 2000, v. 9, n. 8, p. 1177, doi. 10.1093/hmg/9.8.1177

By:

Davies, Rachel C.;
Bratt, Eva;
Hastie, Nicholas D.

Publication type:

Article

Evidence that WT1 mutations in Denys — Drash syndrome patients may act in a dominant-negative fashion.

Published in:

Human Molecular Genetics, 1993, v. 2, n. 3, p. 259

By:

Little, Melissa H.;
Williamson, Kathleen A.;
Mannens, Marcel;
Kelsey, Anna;
Gosden, Christine;
Hastie, Nicholas D.;
Heyningen, Veronica van

Publication type:

Article

Dominant negative mutations in the Wilms tumour (WT1) gene cause Denys-Drash syndrome—proof that a tumour-suppressor gene plays a crucial role in normal genitourinary development.

Published in:

Human Molecular Genetics, 1992, v. 1, n. 5, p. 293

By:

Hastie, Nicholas D.

Publication type:

Article

Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin.

Published in:

Nature Genetics, 2010, v. 42, n. 1, p. 89, doi. 10.1038/ng.494

By:

Martínez-Estrada, Ofelia M.;
Lettice, Laura A.;
Essafi, Abdelkader;
Guadix, Juan Antonio;
Slight, Joan;
Velecela, Víctor;
Hall, Emma;
Reichmann, Judith;
Devenney, Paul S.;
Hohenstein, Peter;
Hosen, Naoki;
Hill, Robert E.;
Muñoz-Chapuli, Ramón;
Hastie, Nicholas D.

Publication type:

Article

Mice Lacking the 68-Amino-Acid, Mammal-Specific N-Terminal Extension of WT1 Develop Normally and Are Fertile.

Published in:

Molecular & Cellular Biology, 2003, v. 23, n. 7, p. 2608, doi. 10.1128/MCB.23.7.2608-2613.2003

By:

Miles, Colin G.;
Slight, Joan;
Spraggon, Lee;
O'Sullivan, Maureen;
Patek, Charles;
Hastie, Nicholas D.

Publication type:

Article

Telomeric repeat from T. thermophila cross hybridizes with human telomeres.

Published in:

Nature, 1988, v. 332, n. 6165, p. 656, doi. 10.1038/332656a0

By:

Allshire, Robin C.;
Gosden, John R.;
Cross, Sally H.;
Cranston, Gwen;
Rout, Derek;
Sugawara, Neal;
Szostak, Jack W.;
Fantes, Peter A.;
Hastie, Nicholas D.

Publication type:

Article