Works by Hassab, Mahmoud A. El

Results: 40

Berberine loaded thermosensitive lipid nanoparticles: in vitro characterization, in silico study, and in vivo anti-arthritic effect.

Published in:

Journal of Liposome Research, 2024, v. 34, n. 2, p. 303, doi. 10.1080/08982104.2023.2273390

By:

Gad, Heba A.;
Abbas, Haidy;
El Sayed, Nesrine S.;
Khattab, Mohamed A.;
El Hassab, Mahmoud A.;
Mansour, Mai

Publication type:

Article

Unexpected Synthesis, Single-Crystal X-ray Structure, Anticancer Activity, and Molecular Docking Studies of Certain 2–((Imidazole/Benzimidazol–2–yl)thio)–1–arylethanones.

Published in:

Crystals (2073-4352), 2020, v. 10, n. 6, p. 446, doi. 10.3390/cryst10060446

By:

Al-Warhi, Tarfah;
Said, Mohamed A.;
El Hassab, Mahmoud A.;
Aljaeed, Nada;
Ghabour, Hazem A.;
Almahli, Hadia;
Eldehna, Wagdy M.;
Abdel-Aziz, Hatem A.

Publication type:

Article

Identification of Novel Cyanopyridones and Pyrido[2,3- D ]Pyrimidines as Anticancer Agents with Dual VEGFR-2/HER-2 Inhibitory Action: Synthesis, Biological Evaluation and Molecular Docking Studies.

Published in:

Pharmaceuticals (14248247), 2022, v. 15, n. 10, p. 1262, doi. 10.3390/ph15101262

By:

Al-Warhi, Tarfah;
Sallam, Al-Aliaa M.;
Hemeda, Loah R.;
El Hassab, Mahmoud A.;
Aljaeed, Nada;
Alotaibi, Ohoud J.;
Doghish, Ahmed S.;
Noshy, Mina;
Eldehna, Wagdy M.;
Ibrahim, Mona H.

Publication type:

Article

A multidisciplinary approach to the antioxidant and hepatoprotective activities of Arbutus pavarii Pampan fruit; in vitro and in Vivo biological evaluations, and in silico investigations.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2024, v. 39, n. 1, p. 1, doi. 10.1080/14756366.2023.2293639

By:

Elshibani, Fatma A.;
Alamami, Abdullah D.;
Mohammed, Hamdoon A.;
Rasheed, Rabab Ahmed;
El Sabban, Radwa M.;
Yehia, Mohamed A.;
Abdel Mageed, Sherif S.;
Majrashi, Taghreed A.;
Elkaeed, Eslam B.;
El Hassab, Mahmoud A.;
Eldehna, Wagdy M.;
El-Ashrey, Mohamed K.

Publication type:

Article

Comparative metabolic study of the chloroform fraction of three Cystoseira species based on UPLC/ESI/MS analysis and biological activities.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2024, v. 39, n. 1, p. 1, doi. 10.1080/14756366.2023.2292482

By:

Aly, Shaza H.;
Elissawy, Ahmed M.;
El Hassab, Mahmoud A.;
Majrashi, Taghreed A.;
Hassan, Fatma E.;
Elkaeed, Eslam B.;
Eldehna, Wagdy M.;
Singab, Abdel Nasser B.

Publication type:

Article

Novel N-Arylmethyl-aniline/chalcone hybrids as potential VEGFR inhibitors: synthesis, biological evaluations, and molecular dynamic simulations.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2023.2278022

By:

Haffez, Hesham;
Elsayed, Nosaiba A.;
Ahmed, Marwa F.;
Fatahala, Samar S.;
Khaleel, Eman F.;
Badi, Rehab Mustafa;
Elkaeed, Eslam B.;
El Hassab, Mahmoud A.;
Hammad, Sherif F.;
Eldehna, Wagdy M.;
Masurier, Nicolas;
El-Haggar, Radwan

Publication type:

Article

Discovery of pyrimidine-tethered benzothiazole derivatives as novel anti-tubercular agents towards multi- and extensively drug resistant Mycobacterium tuberculosis.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2023.2250575

By:

Hemeda, Loah R.;
El Hassab, Mahmoud A.;
Abdelgawad, Mohamed A.;
Khaleel, Eman F.;
Abdel-Aziz, Marwa M.;
Binjubair, Faizah A.;
Al-Rashood, Sara T.;
Eldehna, Wagdy M.;
El-Ashrey, Mohamed K.

Publication type:

Article

Identification of sulphonamide-tethered N-((triazol-4-yl)methyl)isatin derivatives as inhibitors of SARS-CoV-2 main protease.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2023.2234665

By:

ElNaggar, Mai H.;
Elgazar, Abdullah A.;
Gamal, Ghada;
Hamed, Shimaa M.;
Elsayed, Zainab M.;
El-Ashrey, Mohamed K.;
Abood, Amira;
El Hassab, Mahmoud A.;
Soliman, Ahmed M.;
El-Domany, Ramadan A.;
Badria, Farid A.;
Supuran, Claudiu T.;
Eldehna, Wagdy M.

Publication type:

Article

Chemical composition, seasonal variation and antiaging activities of essential oil from Callistemon subulatus leaves growing in Egypt.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2023.2224944

By:

Rabie, Omyma;
El-Nashar, Heba A. S.;
Majrashi, Taghreed A.;
Al‐Warhi, Tarfah;
El Hassab, Mahmoud A.;
Eldehna, Wagdy M.;
Mostafa, Nada M.

Publication type:

Article

Metabolomic profile, anti-trypanosomal potential and molecular docking studies of Thunbergia grandifolia.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2023, v. 38, n. 1, p. 1, doi. 10.1080/14756366.2023.2199950

By:

El-Nashar, Heba A. S.;
Sayed, Ahmed M.;
El-Sherief, Hany A. M.;
Rateb, Mostafa E.;
Akil, Lina;
Khadra, Ibrahim;
Majrashi, Taghreed A.;
Al-Rashood, Sara T.;
Binjubair, Faizah A.;
El Hassab, Mahmoud A.;
Eldehna, Wagdy M.;
Abdelmohsen, Usama Ramadan;
Mostafa, Nada M.

Publication type:

Article

Multi-stage structure-based virtual screening approach towards identification of potential SARS-CoV-2 NSP13 helicase inhibitors.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2022, v. 37, n. 1, p. 563, doi. 10.1080/14756366.2021.2022659

By:

El Hassab, Mahmoud A.;
Eldehna, Wagdy M.;
Al-Rashood, Sara T.;
Alharbi, Amal;
Eskandrani, Razan O.;
Alkahtani, Hamad M.;
Elkaeed, Eslam B.;
Abou-Seri, Sahar M.

Publication type:

Article

GC/MS analysis and potential synergistic effect of mandarin and marjoram oils on Helicobacter pylori.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2022, v. 37, n. 1, p. 1610, doi. 10.1080/14756366.2022.2081846

By:

Elkousy, Rawah H.;
Mostafa, Nada M.;
Abd-alkhalek, Ahmed M.;
El Hassab, Mahmoud A.;
Al-Rashood, Sara T.;
Eldehna, Wagdy M.;
Eldahshan, Omayma A.

Publication type:

Article

Discovery of novel thiazolyl-pyrazolines as dual EGFR and VEGFR-2 inhibitors endowed with in vitro antitumor activity towards non-small lung cancer.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2022, v. 37, n. 1, p. 2265, doi. 10.1080/14756366.2022.2104841

By:

Abdelsalam, Esraa A.;
Abd El-Hafeez, Amer Ali;
Eldehna, Wagdy M.;
El Hassab, Mahmoud A.;
Marzouk, Hala Mohamed M.;
Elaasser, Mahmoud M.;
Abou Taleb, Nageh A.;
Amin, Kamilia M.;
Abdel-Aziz, Hatem A.;
Ghosh, Pradipta;
Hammad, Sherif F.

Publication type:

Article

In silico identification of novel SARS-COV-2 2′-O-methyltransferase (nsp16) inhibitors: structure-based virtual screening, molecular dynamics simulation and MM-PBSA approaches.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 727, doi. 10.1080/14756366.2021.1885396

By:

El Hassab, Mahmoud A.;
Ibrahim, Tamer M.;
Al-Rashood, Sara T.;
Alharbi, Amal;
Eskandrani, Razan O.;
Eldehna, Wagdy M.

Publication type:

Article

Development of novel isatin–nicotinohydrazide hybrids with potent activity against susceptible/resistant Mycobacterium tuberculosis and bronchitis causing–bacteria.

Published in:

Journal of Enzyme Inhibition & Medicinal Chemistry, 2021, v. 36, n. 1, p. 384, doi. 10.1080/14756366.2020.1868450

By:

Elsayed, Zainab M.;
Eldehna, Wagdy M.;
Abdel-Aziz, Marwa M.;
El Hassab, Mahmoud A.;
Elkaeed, Eslam B.;
Al-Warhi, Tarfah;
Abdel-Aziz, Hatem A.;
Abou-Seri, Sahar M.;
Mohammed, Eman R.

Publication type:

Article

Design, synthesis, in vitro biological assessment and molecular modeling insights for novel 3-(naphthalen-1-yl)-4,5-dihydropyrazoles as anticancer agents with potential EGFR inhibitory activity.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-15050-8

By:

Eldehna, Wagdy M.;
El Hassab, Mahmoud A.;
Elsayed, Zainab M.;
Al-Warhi, Tarfah;
Elkady, Hazem;
Abo-Ashour, Mahmoud F.;
Abourehab, Mohammed A. S.;
Eissa, Ibrahim H.;
Abdel-Aziz, Hatem A.

Publication type:

Article

In Vivo and In Silico Investigation of the Anti-Obesity Effects of Lactiplantibacillus plantarum Combined with Chia Seeds, Green Tea, and Chitosan in Alleviating Hyperlipidemia and Inflammation.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 20, p. 12200, doi. 10.3390/ijms232012200

By:

Elebeedy, Dalia;
Ghanem, Aml;
Saleh, Asmaa;
Ibrahim, Mona H.;
Kamaly, Omkulthom Al;
Abourehab, Mohammed A. S.;
Ali, Mohamed A.;
Abd El Maksoud, Ahmed I.;
El Hassab, Mahmoud A.;
Eldehna, Wagdy M.

Publication type:

Article

Multi-Step In Silico Discovery of Natural Drugs against COVID-19 Targeting Main Protease.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 13, p. 6912, doi. 10.3390/ijms23136912

By:

Elkaeed, Eslam B.;
Youssef, Fadia S.;
Eissa, Ibrahim H.;
Elkady, Hazem;
Alsfouk, Aisha A.;
Ashour, Mohamed L.;
El Hassab, Mahmoud A.;
Abou-Seri, Sahar M.;
Metwaly, Ahmed M.

Publication type:

Article

Computational Prediction of the Potential Target of SARS‐CoV‐2 Inhibitor Plitidepsin via Molecular Docking, Dynamic Simulations and MM‐PBSA Calculations.

Published in:

Chemistry & Biodiversity, 2022, v. 19, n. 2, p. 1, doi. 10.1002/cbdv.202100719

By:

El Hassab, Mahmoud A.;
Hemeda, Loah R.;
Elsayed, Zainab M.;
Al‐Rashood, Sara T.;
Abdel‐Hamid Amin, Mohammed K.;
Abdel‐Aziz, Hatem A.;
Eldehna, Wagdy M.

Publication type:

Article

Olive Leaves as a Potential Phytotherapy in the Treatment of COVID-19 Disease; A Mini-Review.

Published in:

Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.879118

By:

Abdelgawad, Shimaa M.;
Hassab, Mahmoud A. El;
Abourehab, Mohammed A. S.;
Elkaeed, Eslam B.;
Eldehna, Wagdy M.

Publication type:

Article

Chemical composition and biological activity of lemongrass volatile oil and n-Hexane extract: GC/MS analysis, in vitro and molecular modelling studies.

Published in:

PLoS ONE, 2025, v. 20, n. 2, p. 1, doi. 10.1371/journal.pone.0319147

By:

Aly, Shaza H.;
Uba, Abdullahi Ibrahim;
Nilofar, Nilofar;
Majrashi, Taghreed A.;
El Hassab, Mahmoud A.;
Eldehna, Wagdy M.;
Zengin, Gokhan;
Eldahshan, Omayma A.

Publication type:

Article

A Modified Green Star Area (MoGSA) and software to assess greenness of reactions in the chemistry laboratories.

Published in:

PLoS ONE, 2024, v. 19, n. 12, p. 1, doi. 10.1371/journal.pone.0314421

By:

Mansour, Fotouh R.;
El Hassab, Mahmoud A.;
Majrashi, Taghreed A.;
Eldehna, Wagdy M.

Publication type:

Article

Exploring the phytochemicals, antioxidant properties, and hepatoprotective potential of Moricandia sinaica leaves against paracetamol-induced toxicity: Biological evaluations and in Silico insights.

Published in:

PLoS ONE, 2024, v. 19, n. 10, p. 1, doi. 10.1371/journal.pone.0307901

By:

Aly, Shaza H.;
Mahmoud, Abdulla M. A.;
Abdel Mageed, Sherif S.;
Khaleel, Eman F.;
Badi, Rehab Mustafa;
Elkaeed, Eslam B.;
Rasheed, Rabab Ahmed;
El Hassab, Mahmoud A.;
Eldehna, Wagdy M.

Publication type:

Article

Synergistic antiviral activity of Lactobacillus acidophilus and Glycyrrhiza glabra against Herpes Simplex-1 Virus (HSV-1) and Vesicular Stomatitis Virus (VSV): experimental and In Silico insights.

Published in:

BMC Microbiology, 2023, v. 23, n. 1, p. 1, doi. 10.1186/s12866-023-02911-z

By:

Elebeedy, Dalia;
Ghanem, Aml;
Aly, Shaza H.;
Ali, Mohamed A.;
Faraag, Ahmed H. I.;
El-Ashrey, Mohamed K.;
salem, Aya M.;
Hassab, Mahmoud A. El;
Maksoud, Ahmed I. Abd El

Publication type:

Article

Comparative Metabolic Study of Tamarindus indica L.'s Various Organs Based on GC/MS Analysis, In Silico and In Vitro Anti-Inflammatory and Wound Healing Activities.

Published in:

Plants (2223-7747), 2023, v. 12, n. 1, p. 87, doi. 10.3390/plants12010087

By:

Aly, Shaza H.;
El-Hassab, Mahmoud A.;
Elhady, Sameh S.;
Gad, Haidy A.

Publication type:

Article

GC/MS Profiling, Anti-Collagenase, Anti-Elastase, Anti-Tyrosinase and Anti-Hyaluronidase Activities of a Stenocarpus sinuatus Leaves Extract.

Published in:

Plants (2223-7747), 2022, v. 11, n. 7, p. 918, doi. 10.3390/plants11070918

By:

Younis, Mai M.;
Ayoub, Iriny M.;
Mostafa, Nada M.;
El Hassab, Mahmoud A.;
Eldehna, Wagdy M.;
Al-Rashood, Sara T.;
Eldahshan, Omayma A.

Publication type:

Article

The Antioxidant and Enzyme Inhibitory Potential of n -Hexane-Extracted Oils Obtained from Three Egyptian Cultivars of the Golden Dewdrop Duranta erecta Linn. Supported by Their GC-MS Metabolome Analysis and Docking Studies.

Published in:

Antioxidants, 2022, v. 11, n. 10, p. N.PAG, doi. 10.3390/antiox11101937

By:

Fayez, Shaimaa;
Zengin, Gokhan;
Al-Rashood, Sara T.;
El Hassab, Mahmoud A.;
Eldehna, Wagdy M.;
Dall'Acqua, Stefano;
Eldahshan, Omayma A.

Publication type:

Article

In vitro biological evaluation and in silico insights into the antiviral activity of standardized olive leaves extract against SARS-CoV-2.

Published in:

PLoS ONE, 2024, v. 19, n. 4, p. 1, doi. 10.1371/journal.pone.0301086

By:

Majrashi, Taghreed A.;
El Hassab, Mahmoud A.;
Mahmoud, Sara H.;
Mostafa, Ahmed;
Wahsh, Engy A.;
Elkaeed, Eslam B.;
Hassan, Fatma E.;
Eldehna, Wagdy M.;
Abdelgawad, Shimaa M.

Publication type:

Article

DFT and molecular simulation validation of the binding activity of PDEδ inhibitors for repression of oncogenic k-Ras.

Published in:

PLoS ONE, 2024, v. 19, n. 3, p. 1, doi. 10.1371/journal.pone.0300035

By:

Majrashi, Taghreed A.;
Sabt, Ahmed;
Almahli, Hadia;
El Hassab, Mahmoud A.;
Noamaan, Mahmoud A.;
Elkaeed, Eslam B.;
Hamissa, Mohamed Farouk;
Maslamani, Abdalkareem Nael;
Shaldam, Moataz A.;
Eldehna, Wagdy M.

Publication type:

Article

Phthalimide‐tethered isatins as novel poly(ADP‐ribose) polymerase inhibitors: Design, synthesis, biological evaluations, and molecular modeling investigations.

Published in:

Archiv der Pharmazie, 2024, v. 357, n. 3, p. 1, doi. 10.1002/ardp.202300599

By:

El Hassab, Mahmoud A.;
El‐Hafeez, Amer Ali Abd;
Almahli, Hadia;
Elsayed, Zainab M.;
Eldehna, Wagdy M.;
Hassan, Ghaneya S.;
Abou‐Seri, Sahar M.

Publication type:

Article

Novel hydrazone‐isatin derivatives as potential EGFR inhibitors: Synthesis and in vitro pharmacological profiling.

Published in:

Archiv der Pharmazie, 2023, v. 356, n. 9, p. 1, doi. 10.1002/ardp.202300244

By:

Ahmed, Marwa F.;
El‐Haggar, Radwan;
Almalki, Atiah H.;
Abdullah, Omeima;
El Hassab, Mahmoud A.;
Masurier, Nicolas;
Hammad, Sherif F.

Publication type:

Article

Toward the Identification of Potential α-Ketoamide Covalent Inhibitors for SARS-CoV-2 Main Protease: Fragment-Based Drug Design and MM-PBSA Calculations.

Published in:

Processes, 2021, v. 9, n. 6, p. 1004, doi. 10.3390/pr9061004

By:

Hassab, Mahmoud A. El;
Fares, Mohamed;
Amin, Mohammed K. Abdel-Hamid;
Al-Rashood, Sara T.;
Alharbi, Amal;
Eskandrani, Razan O.;
Alkahtani, Hamad M.;
Eldehna, Wagdy M.

Publication type:

Article

Identification of potential inhibitors for HCV NS5b of genotype 4a by combining dynamic simulation, protein–ligand interaction fingerprint, 3D pharmacophore, docking and 3D QSAR.

Published in:

Journal of Biomolecular Structure & Dynamics, 2020, v. 38, n. 15, p. 4521, doi. 10.1080/07391102.2019.1685005

By:

El-Hassab, Mahmoud Abd El-Monem;
El-Bastawissy, Eman Esmat;
El-Moselhy, Tarek Fathy

Publication type:

Article

1-Benzyl-5-bromo-3-hydrazonoindolin-2-ones as Novel Anticancer Agents: Synthesis, Biological Evaluation and Molecular Modeling Insights.

Published in:

Molecules, 2023, v. 28, n. 7, p. 3203, doi. 10.3390/molecules28073203

By:

Al-Warhi, Tarfah;
Almahli, Hadia;
Maklad, Raed M.;
Elsayed, Zainab M.;
El Hassab, Mahmoud A.;
Alotaibi, Ohoud J.;
Aljaeed, Nada;
Ayyad, Rezk R.;
Ghabour, Hazem A.;
Eldehna, Wagdy M.;
El-Ashrey, Mohamed K.

Publication type:

Article

Synergistic Effect of Sophora japonica and Glycyrrhiza glabra Flavonoid-Rich Fractions on Wound Healing: In Vivo and Molecular Docking Studies.

Published in:

Molecules, 2023, v. 28, n. 7, p. 2994, doi. 10.3390/molecules28072994

By:

Aly, Shaza H.;
Elissawy, Ahmed M.;
Mahmoud, Abdulla M. A.;
El-Tokhy, Fatma Sa'eed;
Mageed, Sherif S. Abdel;
Almahli, Hadia;
Al-Rashood, Sara T.;
Binjubair, Faizah A.;
Hassab, Mahmoud A. El;
Eldehna, Wagdy M.;
Singab, Abd El-Nasser B.

Publication type:

Article

GC/MS Profiling of the Essential Oil and Lipophilic Extract of Moricandia sinaica Boiss. and Evaluation of Their Cytotoxic and Antioxidant Activities.

Published in:

Molecules, 2023, v. 28, n. 5, p. 2193, doi. 10.3390/molecules28052193

By:

Aly, Shaza H.;
Kandil, Nariman H.;
Hemdan, Roqaya M.;
Kotb, Sara S.;
Zaki, Sara S.;
Abdelaziz, Omnia M.;
AbdelRazek, Mohamed M. M.;
Almahli, Hadia;
El Hassab, Mahmoud A.;
Al-Rashood, Sara T.;
Binjubair, Faizah A.;
Eldehna, Wagdy M.

Publication type:

Article

Chemical Constituents, Antioxidant, and Enzyme Inhibitory Activities Supported by In-Silico Study of n -Hexane Extract and Essential Oil of Guava Leaves.

Published in:

Molecules, 2022, v. 27, n. 24, p. 8979, doi. 10.3390/molecules27248979

By:

Aly, Shaza H.;
Eldahshan, Omayma A.;
Al-Rashood, Sara T.;
Binjubair, Faizah A.;
El Hassab, Mahmoud A.;
Eldehna, Wagdy M.;
Dall'Acqua, Stefano;
Zengin, Gokhan

Publication type:

Article

In Silico Approach Using Free Software to Optimize the Antiproliferative Activity and Predict the Potential Mechanism of Action of Pyrrolizine-Based Schiff Bases.

Published in:

Molecules, 2021, v. 26, n. 13, p. 4002, doi. 10.3390/molecules26134002

By:

Almalki, Faisal A.;
Abdalla, Ashraf N.;
Shawky, Ahmed M.;
El Hassab, Mahmoud A.;
Gouda, Ahmed M.

Publication type:

Article

Multi-stage structure-based virtual screening approach combining 3D pharmacophore, docking and molecular dynamic simulation towards the identification of potential selective PARP-1 inhibitors.

Published in:

BMC Chemistry, 2025, v. 19, n. 1, p. 1, doi. 10.1186/s13065-025-01389-2

By:

El Hassab, Mahmoud A.;
Eldehna, Wagdy M.;
Hassan, Ghaneya S.;
Abou-Seri, Sahar M.

Publication type:

Article

Fenticonazole nitrate loaded trans-novasomes for effective management of tinea corporis: design characterization, in silico study, and exploratory clinical appraisal.

Published in:

Drug Delivery, 2022, v. 29, n. 1, p. 1100, doi. 10.1080/10717544.2022.2057619

By:

Albash, Rofida;
Ragaie, Maha H.;
El Hassab, Mahmoud A.;
El-Haggar, Radwan;
Eldehna, Wagdy M.;
Al-Rashood, Sara T.;
Mosallam, Shaimaa

Publication type:

Article