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Discovery of Small Molecules that Induce the Degradation of Huntingtin.
- Published in:
- Angewandte Chemie, 2017, v. 129, n. 38, p. 11688, doi. 10.1002/ange.201706529
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- Article
Discovery of Small Molecules that Induce the Degradation of Huntingtin.
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- Angewandte Chemie International Edition, 2017, v. 56, n. 38, p. 11530, doi. 10.1002/anie.201706529
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- Publication type:
- Article
Efficient Lead Finding, Activity Enhancement and Preliminary Selectivity Control of Nuclear Receptor Ligands Bearing a Phenanthridinone Skeleton.
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- International Journal of Molecular Sciences, 2018, v. 19, n. 7, p. 2090, doi. 10.3390/ijms19072090
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- Article
Restoration of the reduced CLSP activity alleviates memory impairment in Alzheimer disease.
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- Translational Psychiatry, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41398-020-01168-8
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- Article
Distribution of Retinoids Applied Exogenously to Chick Limb Buds: an Autoradiographic Analysis.
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- Development, Growth & Differentiation, 1993, v. 35, n. 5, p. 593, doi. 10.1111/j.1440-169X.1993.00593.x
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- Article
Transforming growth factor β2 autocrinally mediates neuronal cell death induced by amyloid-β.
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- Journal of Neuroscience Research, 2015, v. 93, n. 6, p. 984, doi. 10.1002/jnr.23582
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- Article
Transforming growth factor β2 autocrinally mediates neuronal cell death induced by amyloid‐β.
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- Journal of Neuroscience Research, 2006, v. 83, n. 6, p. 1039, doi. 10.1002/jnr.20804
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- Article
Expression of N19S‐SOD1, an SOD1 mutant found in sporadic amyotrophic lateral sclerosis patients, induceslow‐grade motoneuronal toxicity.
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- Journal of Neuroscience Research, 2005, v. 81, n. 5, p. 720, doi. 10.1002/jnr.20594
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- Article
Neuroprotective effect of activity‐dependent neurotrophic factor against toxicity from familial amyotrophic lateral sclerosis‐linked mutant SOD1 in vitro and in vivo.
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- Journal of Neuroscience Research, 2004, v. 78, n. 4, p. 542, doi. 10.1002/jnr.20305
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- Article
Cytotoxic mechanisms by M239V presenilin 2, a little‐analyzed Alzheimer's disease‐causative mutant.
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- Journal of Neuroscience Research, 2004, v. 77, n. 4, p. 583, doi. 10.1002/jnr.20163
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- Article
Amino- and carboxyl-terminal mutants of presenilin 1 cause neuronal cell death through distinct toxic mechanisms: Study of 27 different presenilin 1 mutants.
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- Journal of Neuroscience Research, 2004, v. 75, n. 3, p. 417, doi. 10.1002/jnr.10861
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- Article
Characterization of the toxic mechanism triggered by Alzheimer's amyloid-β peptides via p75 neurotrophin receptor in neuronal hybrid cells.
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- Journal of Neuroscience Research, 2003, v. 73, n. 5, p. 627, doi. 10.1002/jnr.10703
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- Article
Synthesis of marine guanidine alkaloids and their application as chemical/biological tools.
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- Chemical Record, 2003, v. 3, n. 4, p. 201, doi. 10.1002/tcr.10064
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- Article
System Development for Tsunami Evacuation Drill Using ICT and Tsunami Inundation Simulation Data.
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- Journal of Disaster Research, 2024, v. 19, n. 1, p. 72, doi. 10.20965/jdr.2024.p0072
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- Article
Image-based screen capturing misfolding status of Niemann-Pick type C1 identifies potential candidates for chaperone drugs.
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- PLoS ONE, 2020, v. 15, n. 12, p. 1, doi. 10.1371/journal.pone.0243746
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- Article
Development of a Femtomolar-Acting Humanin Derivative Named Colivelin by Attaching Activity-Dependent Neurotrophic Factor to Its N Terminus: Characterization of Colivelin-Mediated Neuroprotection against Alzheimer's Disease-Relevant Insults In Vitro and In Vivo.
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- Journal of Neuroscience, 2005, v. 25, n. 44, p. 10252, doi. 10.1523/JNEUROSCI.3348-05.2005
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- Article
Molecular Mechanisms for Neuronal Cell Death by Alzheimer's Amyloid Precursor Protein-Relevant Insults.
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- NeuroSignals (Karger AG), 2002, v. 11, n. 5, p. 236, doi. 10.1159/000067424
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- Article
Distance from the external occipital protuberance to the occipital artery for occipital nerve block.
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- 2013
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- Letter
Evaluation of Electronic States of Polymer Surface Using Photoelectron Spectroscopy in Air.
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- Electrical Engineering in Japan, 2014, v. 188, n. 2, p. 9, doi. 10.1002/eej.22527
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- Article
Effect of oxygen plasma treatment of indium tin oxide for organic solar cell.
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- Electrical Engineering in Japan, 2006, v. 154, n. 4, p. 1, doi. 10.1002/eej.20313
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- Article
VSTM2L is a novel secreted antagonist of the neuroprotective peptide Humanin.
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- FASEB Journal, 2011, v. 25, n. 6, p. 1983, doi. 10.1096/fj.10-163535
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- Article
Cytosolic-nuclear Tumor Promoter-specific Binding Protein: Association with the 90 kDa Heat Shock Protein and Translocation into Nuclei by Treatment with 12-O-Tetradecanoylphorbol 13-Acetate.
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- Cancer Science, 1991, v. 82, n. 6, p. 665, doi. 10.1111/j.1349-7006.1991.tb01902.x
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- Article
Specific Uptake of Retinoids into Human Promyelocytic Leukemia Cells HL-60 by Retinoid-specific Binding Protein: Possibly the True Retinoid Receptor.
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- Cancer Science, 1988, v. 79, n. 4, p. 473, doi. 10.1111/j.1349-7006.1988.tb01616.x
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- Article
Solvent Resistant Honeycomb Films from Photo-Crosslinkable Polycinnamate.
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- Macromolecular Rapid Communications, 2007, v. 28, n. 8, p. 962, doi. 10.1002/marc.200600884
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- Article
Primary combined small and squamous cell carcinoma of the hypopharynx: A case report.
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- 2016
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- Publication type:
- Case Study
Effect of low-energy nitrogen ion treatment of highly ordered pyrolytic graphite on oxygen reduction reaction activity.
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- Nanomaterials & Nanotechnology, 2017, v. 7, p. 1, doi. 10.1177/1847980417690331
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- Article
Effect of surface current on photoelectron emission from mica.
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- Electrical Engineering in Japan, 2000, v. 133, n. 1, p. 1, doi. 10.1002/1520-6416(200010)133:1<1::AID-EEJ1>3.0.CO;2-K
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- Publication type:
- Article
CLSPCOL rescues Alzheimer’s disease mouse models.
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- Translational Neuroscience, 2022, v. 13, n. 1, p. 11, doi. 10.1515/tnsci-2022-0209
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- Publication type:
- Article
Production of N-Lauroylated G Protein α-Subunit in Sf9 Insect Cells: The Type of N-Acyl Group of Gα Influences G Protein–Mediated Signal Transduction.
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- Journal of Biochemistry, 2004, v. 135, n. 3, p. 319, doi. 10.1093/jb/mvh039
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- Article
Induction of SREBP-1c mRNA by Differentiation and LXR Ligand in Human Keratinocytes.
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- Journal of Investigative Dermatology, 2009, v. 129, n. 6, p. 1395, doi. 10.1038/jid.2009.15
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- Article
A mutation protective against Alzheimer's disease renders amyloid β precursor protein incapable of mediating neurotoxicity.
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- Journal of Neurochemistry, 2014, v. 130, n. 2, p. 291, doi. 10.1111/jnc.12717
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- Article
Electric Conductivity of Nucleic Acid Polymer Monolayer.
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- International Journal of Nanoscience, 2002, v. 1, n. 5/6, p. 707, doi. 10.1142/S0219581X02000930
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- Article
Total Synthesis of (+)-Batzelladine A and (−)-Batzelladine D, and Identification of Their Target Protein.
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- Chemistry - A European Journal, 2005, v. 11, n. 23, p. 6878, doi. 10.1002/chem.200500852
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- Article
Enantioselective Total Synthesis of Batzelladine A ( We thank Prof. T. Nakata (Tokyo University of Science) and Dr. H. Koshino (RIKEN) for helpful discussions. This work has been supported by grants from the Pharmacy Research Encouragement Foundation, the Uehara Memorial Foundation, and the Mochida Memorial Foundation for Medical and Pharmaceutical Research. )
- Published in:
- Angewandte Chemie, 2004, v. 116, n. 12, p. 1585, doi. 10.1002/ange.200353200
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- Article
Apollon/Bruce is upregulated by Humanin.
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- Molecular & Cellular Biochemistry, 2014, v. 397, n. 1/2, p. 147, doi. 10.1007/s11010-014-2182-4
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- Article
Improvement in aqueous solubility of achiral symmetric cyclofenil by modification to a chiral asymmetric analog.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-92028-y
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- Article
Deposition of uniform carbon film on silicon substrate by chemical solution process.
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- Electronics & Communications in Japan, 2019, v. 102, n. 10, p. 3, doi. 10.1002/ecj.12206
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- Article
A tripartite motif protein TRIM11 binds and destabilizes Humanin, a neuroprotective peptide against Alzheimer's disease-relevant insults.
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- European Journal of Neuroscience, 2003, v. 17, n. 6, p. 1150, doi. 10.1046/j.1460-9568.2003.02553.x
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- Publication type:
- Article
Diastereoselective and Enantioselective Henry (Nitroaldol) Reaction Utilizing a Guanidine-Thiourea Bifunctional Organocatalyst.
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- European Journal of Organic Chemistry, 2006, v. 2006, n. 13, p. 2894, doi. 10.1002/ejoc.200600307
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- Article
Cleavage and inactivation of antiapoptotic Akt/PKB by caspases during apoptosis.
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- Journal of Cellular Physiology, 2000, v. 182, n. 2, p. 290, doi. 10.1002/(SICI)1097-4652(200002)182:2<290::AID-JCP18>3.0.CO;2-8
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- Article
Cover Picture: Improvement in Aqueous Solubility of Retinoic Acid Receptor (RAR) Agonists by Bending the Molecular Structure (Chem. Asian J. 15/2016).
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- Chemistry - An Asian Journal, 2016, v. 11, n. 15, p. 2086, doi. 10.1002/asia.201600924
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- Publication type:
- Article
Improvement in Aqueous Solubility of Retinoic Acid Receptor (RAR) Agonists by Bending the Molecular Structure.
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- Chemistry - An Asian Journal, 2016, v. 11, n. 15, p. 2210, doi. 10.1002/asia.201600744
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- Publication type:
- Article
Humanin antagonists: mutants that interfere with dimerization inhibit neuroprotection by Humanin.
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- European Journal of Neuroscience, 2004, v. 19, n. 9, p. 2356, doi. 10.1111/j.0953-816X.2004.03298.x
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- Article
Origin of Chemoselectivity of TMP Zincate Bases and Differences between TMP Zincate and Alkyl Lithium Reagents: A DFT Study on Model Systems.
- Published in:
- Angewandte Chemie International Edition, 2007, v. 46, n. 6, p. 926, doi. 10.1002/anie.200602664
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- Publication type:
- Article
Enantioselective Total Synthesis of Batzelladine A ( We thank Prof. T. Nakata (Tokyo University of Science) and Dr. H. Koshino (RIKEN) for helpful discussions. This work has been supported by grants from the Pharmacy Research Encouragement Foundation, the Uehara Memorial Foundation, and the Mochida Memorial Foundation for Medical and Pharmaceutical Research. )
- Published in:
- Angewandte Chemie International Edition, 2004, v. 43, n. 12, p. 1559, doi. 10.1002/anie.200353200
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- Publication type:
- Article
C
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- Angewandte Chemie International Edition, 2002, v. 41, n. 15, p. 2832, doi. 10.1002/1521-3773(20020802)41:15<2832::AID-ANIE2832>3.0.CO;2-Q
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- Publication type:
- Article
Specific degradation of CRABP-II via cIAP1-mediated ubiquitylation induced by hybrid molecules that crosslink cIAP1 and the target protein
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- FEBS Letters, 2011, v. 585, n. 8, p. 1147, doi. 10.1016/j.febslet.2011.03.019
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- Publication type:
- Article
Guanidine-Thiourea Bifunctional Organocatalyst for the Asymmetric Henry (Nitroaldol) Reaction.
- Published in:
- Advanced Synthesis & Catalysis, 2005, v. 347, n. 11-13, p. 1643, doi. 10.1002/adsc.200505148
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- Article
Development of Tetrachlorophthalimides as Liver X Receptor β (LXRβ)-Selective Agonists.
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- ChemMedChem, 2016, v. 11, n. 20, p. 2347, doi. 10.1002/cmdc.201600305
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- Article
Determination of the Critical Amino Acids Involved in the Peroxisome Proliferator-Activated Receptor (PPAR) δ Selectivity of Phenylpropanoic Acid-Derived Agonists.
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- ChemMedChem, 2008, v. 3, n. 11, p. 1662, doi. 10.1002/cmdc.200800193
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- Article