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Capability of a large bacterial artificial chromosome clone harboring multiple biosynthetic gene clusters for the production of diverse compounds.
- Published in:
- Journal of Antibiotics, 2024, v. 77, n. 5, p. 288, doi. 10.1038/s41429-024-00711-9
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- Article
In Vitro Module Editing Of NRPS Enables Production Of Highly Potent G<sub>q</sub>‐Signaling Inhibitor FR900359 Derived From Unculturable Plant Symbiont.
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- Angewandte Chemie, 2024, v. 136, n. 10, p. 1, doi. 10.1002/ange.202317805
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- Publication type:
- Article
In Vitro Module Editing Of NRPS Enables Production Of Highly Potent G<sub>q</sub>‐Signaling Inhibitor FR900359 Derived From Unculturable Plant Symbiont.
- Published in:
- Angewandte Chemie International Edition, 2024, v. 63, n. 10, p. 1, doi. 10.1002/anie.202317805
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- Publication type:
- Article
Acyltransferase Domain Exchange between Two Independent Type I Polyketide Synthases in the Same Producer Strain of Macrolide Antibiotics.
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- ChemBioChem, 2023, v. 24, n. 6, p. 1, doi. 10.1002/cbic.202200670
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- Article
Primary leiomyoma of the ureter: a case report.
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- 2021
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- Publication type:
- journal article
An Atypical Arginine Dihydrolase Involved in the Biosynthesis of Cyclic Hexapeptide Longicatenamides.
- Published in:
- Chemistry - An Asian Journal, 2021, v. 16, n. 11, p. 1382, doi. 10.1002/asia.202100181
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- Article
Novel Plant-Associated Acidobacteria Promotes Growth of Common Floating Aquatic Plants, Duckweeds.
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- Microorganisms, 2021, v. 9, n. 6, p. 1133, doi. 10.3390/microorganisms9061133
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- Article
Identification of functional cytochrome P450 and ferredoxin from Streptomyces sp. EAS-AB2608 by transcriptional analysis and their heterologous expression.
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- Applied Microbiology & Biotechnology, 2021, v. 105, n. 10, p. 4177, doi. 10.1007/s00253-021-11304-z
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- Article
Hemiacetal-less rapamycin derivatives designed and produced by genetic engineering of a type I polyketide synthase.
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- Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-88583-z
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- Article
A novel oxazole-containing tetraene compound, JBIR-159, produced by heterologous expression of the cryptic trans-AT type polyketide synthase biosynthetic gene cluster.
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- Journal of Antibiotics, 2021, v. 74, n. 5, p. 354, doi. 10.1038/s41429-021-00410-9
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- Publication type:
- Article
A novel methymycin analog, 12-ketomethymycin N-oxide, produced by the heterologous expression of the large pikromycin/methymycin biosynthetic gene cluster of Streptomyces sp. AM4900.
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- Bioscience, Biotechnology & Biochemistry, 2021, v. 85, n. 4, p. 890, doi. 10.1093/bbb/zbaa111
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- Article
Identification, cloning and heterologous expression of biosynthetic gene cluster for desertomycin.
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- Journal of Antibiotics, 2020, v. 73, n. 9, p. 650, doi. 10.1038/s41429-020-0319-0
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- Publication type:
- Article
In vitro Cas9-assisted editing of modular polyketide synthase genes to produce desired natural product derivatives.
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- Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-17769-2
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- Article
C-Methylation of S-adenosyl-L-Methionine Occurs Prior to Cyclopropanation in the Biosynthesis of 1-Amino-2-Methylcyclopropanecarboxylic Acid (Norcoronamic Acid) in a Bacterium.
- Published in:
- Biomolecules (2218-273X), 2020, v. 10, n. 5, p. 775, doi. 10.3390/biom10050775
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- Article
Novel macrolactam compound produced by the heterologous expression of a large cryptic biosynthetic gene cluster of Streptomyces rochei IFO12908.
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- Journal of Antibiotics, 2020, v. 73, n. 3, p. 171, doi. 10.1038/s41429-019-0265-x
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- Publication type:
- Article
Reprogramming of the antimycin NRPS-PKS assembly lines inspired by gene evolution.
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- Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-05877-z
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- Publication type:
- Article
Monthly oral ibandronate 100 mg is as effective as monthly intravenous ibandronate 1 mg in patients with various pathologies in the MOVEST study.
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- 2018
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- Publication type:
- journal article
Intermittent Ibandronate Maintains Bone Mass, Bone Structure, and Biomechanical Strength of Trabecular and Cortical Bone After Discontinuation of Parathyroid Hormone Treatment in Ovariectomized Rats.
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- 2017
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- Publication type:
- journal article
Frontispiz: Characterization of Giant Modular PKSs Provides Insight into Genetic Mechanism for Structural Diversification of Aminopolyol Polyketides.
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- Angewandte Chemie, 2017, v. 129, n. 7, p. n/a, doi. 10.1002/ange.201780761
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- Publication type:
- Article
Characterization of Giant Modular PKSs Provides Insight into Genetic Mechanism for Structural Diversification of Aminopolyol Polyketides.
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- Angewandte Chemie, 2017, v. 129, n. 7, p. 1766, doi. 10.1002/ange.201611371
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- Publication type:
- Article
Frontispiece: Characterization of Giant Modular PKSs Provides Insight into Genetic Mechanism for Structural Diversification of Aminopolyol Polyketides.
- Published in:
- Angewandte Chemie International Edition, 2017, v. 56, n. 7, p. n/a, doi. 10.1002/anie.201780761
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- Publication type:
- Article
Characterization of Giant Modular PKSs Provides Insight into Genetic Mechanism for Structural Diversification of Aminopolyol Polyketides.
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- Angewandte Chemie International Edition, 2017, v. 56, n. 7, p. 1740, doi. 10.1002/anie.201611371
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- Publication type:
- Article
Effect of monthly intravenous ibandronate injections on vertebral or non-vertebral fracture risk in Japanese patients with high-risk osteoporosis in the MOVER study.
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- 2017
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- Publication type:
- journal article
Higher response with bone mineral density increase with monthly injectable ibandronate 1 mg compared with oral risedronate in the MOVER study.
- Published in:
- 2016
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- Publication type:
- journal article
Identification of the Fluvirucin B 2 (Sch 38518) Biosynthetic Gene Cluster from Actinomadura fulva subsp. indica ATCC 53714: substrate Specificity of the β-Amino Acid Selective Adenylating Enzyme FlvN.
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- Bioscience, Biotechnology & Biochemistry, 2016, v. 80, n. 5, p. 935, doi. 10.1080/09168451.2015.1132155
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- Publication type:
- Article
Novel thioviridamide derivative-JBIR-140: heterologous expression of the gene cluster for thioviridamide biosynthesis.
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- Journal of Antibiotics, 2015, v. 68, n. 8, p. 533, doi. 10.1038/ja.2015.20
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- Publication type:
- Article
Erratum to: Application of Modeling and Simulation to a Long-Term Clinical Trial: A Direct Comparison of Simulated Data and Data Actually Observed in Japanese Osteoporosis Patients Following 3-Year Ibandronate Treatment.
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- Clinical Pharmacokinetics, 2015, v. 54, n. 4, p. 455, doi. 10.1007/s40262-015-0263-5
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- Publication type:
- Article
Application of Modeling and Simulation to a Long-Term Clinical Trial: A Direct Comparison of Simulated Data and Data Actually Observed in Japanese Osteoporosis Patients Following 3-Year Ibandronate Treatment.
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- Clinical Pharmacokinetics, 2015, v. 54, n. 3, p. 295, doi. 10.1007/s40262-014-0206-6
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- Publication type:
- Article
MBJ-0086 and MBJ-0087, new bicyclic depsipeptides, from Sphaerisporangium sp. 33226.
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- Journal of Antibiotics, 2015, v. 68, n. 1, p. 67, doi. 10.1038/ja.2014.98
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- Publication type:
- Article
Increased Bone Mineral Density with Monthly Intravenous Ibandronate Contributes to Fracture Risk Reduction in Patients with Primary Osteoporosis: Three-Year Analysis of the MOVER Study.
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- Calcified Tissue International, 2014, v. 95, n. 6, p. 557, doi. 10.1007/s00223-014-9927-7
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- Article
Identification and Biosynthesis of New Acyloins from the Thermophilic Bacterium Thermosporothrix hazakensis SK20 -1<sup>T</sup>.
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- ChemBioChem, 2014, v. 15, n. 4, p. 527, doi. 10.1002/cbic.201300690
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- Article
Clinical Efficacy on Fracture Risk and Safety of 0.5 mg or 1 mg/month Intravenous Ibandronate Versus 2.5 mg/day Oral Risedronate in Patients with Primary Osteoporosis.
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- Calcified Tissue International, 2013, v. 93, n. 2, p. 137, doi. 10.1007/s00223-013-9734-6
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- Publication type:
- Article
A new 16-membered tetraene macrolide JBIR-100 from a newly identified Streptomyces species.
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- Journal of Antibiotics, 2011, v. 64, n. 5, p. 399, doi. 10.1038/ja.2011.20
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- Article
Isolation of 2 new naphthablin analogs, JBIR-79 and JBIR-80, from Streptomyces sp. RI24.
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- Journal of Antibiotics, 2010, v. 63, n. 12, p. 729, doi. 10.1038/ja.2010.120
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- Publication type:
- Article
A new 16-membered tetraene macrolide JBIR-100 from a newly identified Streptomyces species.
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- Journal of Antibiotics, 2010, v. 63, n. 10, p. 627, doi. 10.1038/ja.2010.104
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- Article
Isolation of two new terpeptin analogs—JBIR-81 and JBIR-82—from a seaweed-derived fungus, Aspergillus sp. SpD081030G1f1.
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- Journal of Antibiotics, 2010, v. 63, n. 7, p. 389, doi. 10.1038/ja.2010.57
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- Article
JBIR-65, a new diterpene, isolated from a sponge-derived Actinomadura sp. SpB081030SC-15.
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- Journal of Antibiotics, 2010, v. 63, n. 7, p. 401, doi. 10.1038/ja.2010.61
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- Publication type:
- Article
JBIR-83 and JBIR-84, new promothiocin derivatives, isolated from Streptomyces sp. RI19.
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- Journal of Antibiotics, 2010, v. 63, n. 7, p. 405, doi. 10.1038/ja.2010.66
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- Publication type:
- Article
JBIR-59, a new sorbicillinoid, from a marine-derived fungus Penicillium citrinum SpI080624G1f01.
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- Journal of Antibiotics, 2010, v. 63, n. 4, p. 203, doi. 10.1038/ja.2010.19
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- Article
Screening and evaluation of new inhibitors of hepatic glucose production.
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- Journal of Antibiotics, 2009, v. 62, n. 11, p. 625, doi. 10.1038/ja.2009.93
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- Publication type:
- Article
New sesquiterpenes, JBIR-27 and -28, isolated from a tunicate-derived fungus, Penicillium sp. SS080624SCf1.
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- Journal of Antibiotics, 2009, v. 62, n. 5, p. 247, doi. 10.1038/ja.2009.21
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- Article
Stawamycin Analog, JBIR-11 from Streptomyces viridochromogenes subsp. sulfomycini NBRC 13830.
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- Journal of Antibiotics, 2008, v. 61, n. 5, p. 326, doi. 10.1038/ja.2008.47
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- Publication type:
- Article
A Novel Indole-diterpenoid, JBIR-03 with Anti-MRSA Activity from Dichotomomyces cejpii var. cejpii NBRC 103559.
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- Journal of Antibiotics, 2007, v. 60, n. 10, p. 645, doi. 10.1038/ja.2007.83
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- Publication type:
- Article
New Aureothin Derivative, Alloaureothin, from Streptomyces sp. MM23.
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- Journal of Antibiotics, 2007, v. 60, n. 5, p. 321, doi. 10.1038/ja.2007.41
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- Publication type:
- Article
Regulation of Proliferation and Chondrogenic Differentiation of Human Mesenchymal Stem Cells by Laminin-5 (Laminin-332).
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- Stem Cells, 2006, v. 24, n. 11, p. 2346, doi. 10.1634/stemcells.2005-0605
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- Article
22-Oxa Calcitriol Is a Less Potent Regulator of Keratinocyte Proliferation and Differentiation Due to Decreased Cellular Uptake and Enhanced Catabolism.
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- Journal of Investigative Dermatology, 1995, v. 105, n. 5, p. 693, doi. 10.1111/1523-1747.ep12324474
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- Article