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Batch-mode microfluidic radiosynthesis of N-succinimidyl-4-[.
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- Journal of Labelled Compounds & Radiopharmaceuticals, 2011, v. 54, n. 3, p. 117, doi. 10.1002/jlcr.1826
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- Article
Novel avenues of tau research.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 3, p. 2240, doi. 10.1002/alz.13533
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- Article
Plasma pTau‐217 and N‐terminal tau (NTA) enhance sensitivity to identify tau PET positivity in amyloid‐β positive individuals.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 2, p. 1166, doi. 10.1002/alz.13528
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- Article
Plasma phosphorylated tau‐217 exhibits sex‐specific prognostication of cognitive decline and brain atrophy in cognitively unimpaired adults.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2024, v. 20, n. 1, p. 376, doi. 10.1002/alz.13454
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- Article
Plasma pTau217: single vs multiple phospho‐site assays.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082953
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Update to the comparative analytical performance of plasma Aβ assays and their relationship to amyloid PET.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082763
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- Article
Fast accumulators of tau have higher levels of plasma pTau and stronger associations with amyloid in later Braak regions at baseline.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079999
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- Article
In‐vivo Braak Stage Distribution of Screened and Randomized Participants from Auτonomy, a Phase 2 Anti‐p‐tau Monoclonal Antibody Trial in Early Symptomatic Alzheimer's Disease.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078006
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Associations of Age and Sex with Levels of Tau PET in Screened Participants from Auτonomy, a Phase 2 Anti‐p‐tau Monoclonal Antibody Trial in Early Symptomatic Alzheimer's Disease.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078469
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Plasma biomarkers of tau for the differentiation between slow and fast tau‐PET accumulators.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080098
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Harmonization of tau‐PET in Alzheimer's disease: comparison of methods to derive CenTauR units for [<sup>18</sup>F]RO948, [<sup>18</sup>F]Flortaucipir, and [<sup>18</sup>F]MK‐6240.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.080421
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- Article
Plasma ALZpath p‐tau217 for the identification of amyloid and tau positivity.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.079892
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Prognostic utility of plasma p217+tau vs amyloid and tau PET in the Alzheimer's continuum.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.078042
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Plasma p‐tau231 and p‐tau217 provides information on tau tangle deposition in symptomatic Alzheimer's disease individuals.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076691
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Harmonization of tau‐PET in Alzheimer's disease: comparison of methods to derive CenTauR units for [18F]RO948, [18F]Flortaucipir, and [18F]MK‐6240.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.082006
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- Article
Plasma biomarkers of tau for the differentiation between slow and fast tau‐PET accumulators.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081969
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- Article
Associations of Age and Sex with Levels of Tau PET in Screened Participants from Auτonomy, a Phase 2 Anti‐p‐tau Monoclonal Antibody Trial in Early Symptomatic Alzheimer's Disease.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081813
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- Article
In‐vivo Braak Stage Distribution of Screened and Randomized Participants from Auτonomy, a Phase 2 Anti‐p‐tau Monoclonal Antibody Trial in Early Symptomatic Alzheimer's Disease.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 10, p. 1, doi. 10.1002/alz.081781
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Comparative analytical performance of multiple plasma Aβ42 and Aβ40 assays and their ability to predict positron emission tomography amyloid positivity.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 3, p. 956, doi. 10.1002/alz.12697
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A head‐to‐head comparison of plasma phosphorylated tau assays in the real‐world memory clinic.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 6, p. 1, doi. 10.1002/alz.065391
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Plasma p217+tau concordance with <sup>18</sup>F‐NAV4694 beta‐amyloid and <sup>18</sup>F‐MK6240 tau PET in mild Alzheimer's disease and cognitively unimpaired participants in the AIBL/ADNeT cohort.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.055706
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Comparative analytical performance of multiple plasma amyloid‐beta assays and their relationship to amyloid PET.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.055504
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Evaluation of <sup>18</sup>F‐JNJ‐067 as a tau tracer: Neuroimaging / New imaging methods.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.040651
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FTS3‐01‐04: FINAL EFFICACY, SAFETY AND BIOMARKER RESULTS OF THE PHASE 2B/3 RANDOMIZED, DOUBLE‐BLINDED, PLACEBO‐CONTROLLED EARLY TRIAL OF ATABECESTAT IN PRECLINICAL ALZHEIMER'S DISEASE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P873, doi. 10.1016/j.jalz.2019.06.4621
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P1‐257: LONGITUDINAL COMPARISON OF CSF BIOMARKERS OF NEURODEGENERATION IN PATIENTS WITH PROBABLE IDIOPATHIC NORMAL PRESSURE HYDROCEPHALUS (INPH).
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P337, doi. 10.1016/j.jalz.2019.06.812
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P1‐052: A SINGLE ASCENDING DOSE STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF THE ANTI‐PHOSPHO‐TAU ANTIBODY JNJ‐63733657 IN HEALTHY SUBJECTS.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P252, doi. 10.1016/j.jalz.2019.06.077
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P2‐372: IMAGING ALZHEIMER'S TAU PATHOLOGY IN HUMANS: [18F]JNJ‐067—A PHASE 0 EXPLORATORY STUDY IN HEALTHY VOLUNTEERS AND SUBJECTS WITH PROBABLE ALZHEIMER'S DISEASE.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2018, v. 14, p. P838, doi. 10.1016/j.jalz.2018.06.1063
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- Article
PRE-CLINICAL CHARACTERIZATION OF THE NOVEL TAU PET LIGAND [18F]-JNJ'067.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1069, doi. 10.1016/j.jalz.2017.06.1531
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[18F]THK-5117-PET AND [11C]PIB-PET IMAGING IN IDIOPATHIC NORMAL PRESSURE HYDROCEPHALUS (INPH) IN RELATION TO CONFIRMED AMYLOID-β PLAQUES AND TAU IN BRAIN BIOPSIES.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P1537, doi. 10.1016/j.jalz.2017.07.672
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[<sup>18</sup>F]T807, a novel tau positron emission tomography imaging agent for Alzheimer's disease.
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- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2013, v. 9, n. 6, p. 666, doi. 10.1016/j.jalz.2012.11.008
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Novel syntheses of polysubstituted pyrroles and oxazoles by 1,3-dipolar cycloaddition reactions of benzotriazole-stabilized nitrile ylides.
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- Journal of Heterocyclic Chemistry, 2002, v. 39, n. 4, p. 759, doi. 10.1002/jhet.5570390422
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- Article
Comparison of the Bioactive Conformations of Sialyl Lewis<sup>X</sup> and a Potent Sialyl Lewis<sup>X</sup> Mimic.
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- Angewandte Chemie International Edition, 1997, v. 36, n. 23, p. 2603, doi. 10.1002/anie.199726031
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Evaluation of [ 18 F]-JNJ-64326067-AAA tau PET tracer in humans.
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- Journal of Cerebral Blood Flow & Metabolism, 2021, v. 41, n. 12, p. 3302, doi. 10.1177/0271678X211031035
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- Article
Preclinical evaluation and non‐human primate receptor occupancy study of <sup>18</sup>F‐JNJ‐64413739, a novel PET radioligand for P2X7 receptors.
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- Journal of Nuclear Medicine, 2019, v. 60, n. 12, p. 1, doi. 10.2967/jnumed.118.212696
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Preclinical Evaluation and Nonhuman Primate Receptor Occupancy Study of <sup>18</sup>F-JNJ-64413739, a PET Radioligand for P2X7 Receptors.
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- Journal of Nuclear Medicine, 2019, v. 60, n. 8, p. 1154, doi. 10.2967/jnumed.118.212696
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- Article
Biodistribution and Radiation Dosimetry of <sup>18</sup>F-CP-18, a Potential Apoptosis Imaging Agent, as Determined from PET/CT Scans in Healthy Volunteers.
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- Journal of Nuclear Medicine, 2013, v. 54, n. 12, p. 2087, doi. 10.2967/jnumed.113.119800
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- Article
Biodistribution and Radiation Dosimetry of the Integrin Marker <sup>18</sup>F-RGD-K5 Determined from Whole-Body PET/CT in Monkeys and Humans.
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- Journal of Nuclear Medicine, 2012, v. 53, n. 5, p. 787, doi. 10.2967/jnumed.111.088955
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Design and Optimization of Coin-Shaped Microreactor Chips for PET Radiopharmaceutical Synthesis.
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- Journal of Nuclear Medicine, 2010, v. 51, n. 2, p. 282, doi. 10.2967/jnumed.109.065946
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- Article
Integrated Microfluidics for Parallel Screening of an In Situ Click Chemistry Library.
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- Angewandte Chemie, 2006, v. 118, n. 32, p. 5402, doi. 10.1002/ange.200601677
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- Article
Inhibitors of HIV-1 Protease by Using In Situ Click ChemistryWe thank the National Institute of General Medical Sciences, the National Institutes of Health (GM048870), the Skaggs Institute for Chemical Biology, and the W. M. Keck Foundation (K.B.S.) for financial support.
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- Angewandte Chemie, 2006, v. 118, n. 9, p. 1463, doi. 10.1002/ange.200502161
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- Article
Titelbild: “On Water”: Unique Reactivity of Organic Compounds in Aqueous Suspension (Angew. Chem. 21/2005).
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- Angewandte Chemie, 2005, v. 117, n. 21, p. 3219, doi. 10.1002/ange.200590069
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- Article
“On Water”: Unique Reactivity of Organic Compounds in Aqueous SuspensionWe thank Dr. Vladislav Litosh for carrying out preliminary work. Support from the National Institutes of Health, National Institute of General Medical Sciences (GM 28384), the National Science Foundation (CHE9985553), the Skaggs Institute for Chemical Biology, and the W. M. Keck Foundation is gratefully acknowledged. S.N. thanks the Skaggs Institute for a postdoctoral fellowship. We also thank Dr. Suresh Suri, Edwards Air Force Base, California, for a generous gift of quadricyclane. We urge our fellow chemists to float their problematic reactions on water and to send observations of success or failure to us at onwater@scripps.edu for public dissemination with attribution.
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- Angewandte Chemie, 2005, v. 117, n. 21, p. 3339, doi. 10.1002/ange.200462883
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- Article
In Situ Click Chemistry: Enzyme-Generated Inhibitors of Carbonic Anhydrase IIWe thank the National Institute of General Medical Sciences, the National Institutes of Health (K.B.S., C.H.W.), the Skaggs Institute for Chemical Biology (H.C.K., K.B.S.; V.M. is a Skaggs Postdoctoral Fellow), and the W. M. Keck Foundation (K.B.S.) for financial support. We also thank Professor M. G. Finn and Professor V. V. Fokin for valuable discussions.
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- Angewandte Chemie, 2005, v. 117, n. 1, p. 118, doi. 10.1002/ange.200461580
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- Article
Development of Tools for the Design of Selectin Antagonists.
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- Chemistry - A European Journal, 1997, v. 3, n. 10, p. 1571, doi. 10.1002/chem.19970031006
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- Article
Plasma p217+tau versus NAV4694 amyloid and MK6240 tau PET across the Alzheimer's continuum.
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- Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 2022, v. 14, n. 1, p. 1, doi. 10.1002/dad2.12307
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- Article
Development and validation of a high‐sensitivity assay for measuring p217+tau in plasma.
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- Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 2021, v. 13, n. 1, p. 1, doi. 10.1002/dad2.12204
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- Publication type:
- Article
Integrated Microfluidics for Parallel Screening of an In Situ Click Chemistry Library.
- Published in:
- Angewandte Chemie International Edition, 2006, v. 45, n. 32, p. 5276, doi. 10.1002/anie.200601677
- By:
- Publication type:
- Article
Inhibitors of HIV-1 Protease by Using In Situ Click ChemistryWe thank the National Institute of General Medical Sciences, the National Institutes of Health (GM048870), the Skaggs Institute for Chemical Biology, and the W. M. Keck Foundation (K.B.S.) for financial support.
- Published in:
- Angewandte Chemie International Edition, 2006, v. 45, n. 9, p. 1435, doi. 10.1002/anie.200502161
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- Publication type:
- Article
Cover Picture: “On Water”: Unique Reactivity of Organic Compounds in Aqueous Suspension (Angew. Chem. Int. Ed. 21/2005).
- Published in:
- Angewandte Chemie International Edition, 2005, v. 44, n. 21, p. 3157, doi. 10.1002/anie.200590069
- By:
- Publication type:
- Article
“On Water”: Unique Reactivity of Organic Compounds in Aqueous SuspensionWe thank Dr. Vladislav Litosh for carrying out preliminary work. Support from the National Institutes of Health, National Institute of General Medical Sciences (GM 28384), the National Science Foundation (CHE9985553), the Skaggs Institute for Chemical Biology, and the W. M. Keck Foundation is gratefully acknowledged. S.N. thanks the Skaggs Institute for a postdoctoral fellowship. We also thank Dr. Suresh Suri, Edwards Air Force Base, California, for a generous gift of quadricyclane. We urge our fellow chemists to float their problematic reactions on water and to send observations of success or failure to us at onwater@scripps.edu for public dissemination with attribution.
- Published in:
- Angewandte Chemie International Edition, 2005, v. 44, n. 21, p. 3275, doi. 10.1002/anie.200462883
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- Publication type:
- Article