Works by Harrison, Leonard C.

Results: 141

Regulatory Lymphocytes: Antigen-induced regulatory T cells in autoimmunity.

Published in:

Nature Reviews Immunology, 2003, v. 3, n. 3, p. 223, doi. 10.1038/nri1029

By:

von Herrath, Matthias G.;
Harrison, Leonard C.

Publication type:

Article

Household size, T regulatory cell development, and early allergic disease: a birth cohort study.

Published in:

Pediatric Allergy & Immunology, 2022, v. 33, n. 6, p. 1, doi. 10.1111/pai.13810

By:

Ponsonby, Anne‐Louise;
Collier, Fiona;
O'Hely, Martin;
Tang, Mimi L. K.;
Ranganathan, Sarath;
Gray, Lawrence;
Morwitch, Ellen;
Saffery, Richard;
Burgner, David;
Dwyer, Terence;
Sly, Peter D.;
Harrison, Leonard C.;
Vuillermin, Peter

Publication type:

Article

Evaluation of protocol amendments to the Environmental Determinants of Islet Autoimmunity (ENDIA) study during the COVID‐19 pandemic.

Published in:

2021

By:

Penno, Megan A. S.;
Anderson, Amanda J.;
Thomson, Rebecca L.;
McGorm, Kelly;
Barry, Simon C.;
Colman, Peter G.;
Craig, Maria E.;
Davis, Elizabeth A.;
Harris, Mark;
Haynes, Aveni;
Morahan, Grant;
Oakey, Helena;
Rawlinson, William D.;
Sinnott, Richard O.;
Soldatos, Georgia;
Vuillermin, Peter J.;
Wentworth, John M.;
Harrison, Leonard C.;
Couper, Jennifer J.

Publication type:

Letter to the Editor

Specific Sialoforms Required for the Immune Suppressive Activity of Human Soluble CD52.

Published in:

Frontiers in Immunology, 2019, p. 1, doi. 10.3389/fimmu.2019.01967

By:

Shathili, Abdulrahman M.;
Bandala-Sanchez, Esther;
John, Alan;
Goddard-Borger, Ethan D.;
Thaysen-Andersen, Morten;
Everest-Dass, Arun V.;
Adams, Timothy E.;
Harrison, Leonard C.;
Packer, Nicolle H.

Publication type:

Article

Enhanced insulin-receptor tyrosine kinase activity associated with chromosomal translocation (1;19) in a pre-B-cell leukemia line.

Published in:

International Journal of Cancer, 1992, v. 50, n. 3, p. 500, doi. 10.1002/ijc.2910500328

By:

Newman, Julie D.;
Harrison, Leonard C.;
Eckardt, Glenn S.;
Jack, Ian

Publication type:

Article

Insulin receptor expression in burkitt lymphoma cell lines.

Published in:

International Journal of Cancer, 1989, v. 44, n. 3, p. 467, doi. 10.1002/ijc.2910440315

By:

Newman, Julie D.;
Harrison, Leonard C.

Publication type:

Article

Linkage disequilibrium of a type 1 diabetes susceptibility locus with a regulatory IL12B allele.

Published in:

Nature Genetics, 2001, v. 27, n. 2, p. 218, doi. 10.1038/84872

By:

Morahan, Grant;
Huang, Dexing;
Ymer, Susie I.;
Cancilla, Michael R.;
Stephen, Katrina;
Dabadghao, Preeti;
Werther, George;
Tait, Brian D.;
Harrison, Leonard C.;
Colman, Peter G.

Publication type:

Article

Editorial: Does Insulin Resistance Need Resistin?

Published in:

Journal of Clinical Endocrinology & Metabolism, 2007, v. 92, n. 6, p. 2036, doi. 10.1210/jc.2007-0815

By:

Wentworth, John M.;
Harrison, Leonard C.

Publication type:

Article

Controversies in medicine: redefining the diagnosis of type 1 diabetes.

Published in:

2019

By:

Couper, Jennifer J;
Harrison, Leonard C

Publication type:

journal article

Simplifying prediction of disease progression in pre-symptomatic type 1 diabetes using a single blood sample.

Published in:

Diabetologia, 2021, v. 64, n. 11, p. 2432, doi. 10.1007/s00125-021-05523-2

By:

Bediaga, Naiara G.;
Li-Wai-Suen, Connie S. N.;
Haller, Michael J.;
Gitelman, Stephen E.;
Evans-Molina, Carmella;
Gottlieb, Peter A.;
Hippich, Markus;
Ziegler, Anette-Gabriele;
Lernmark, Ake;
DiMeglio, Linda A.;
Wherrett, Diane K.;
Colman, Peter G.;
Harrison, Leonard C.;
Wentworth, John M.

Publication type:

Article

Clinical trial data validate the C-peptide estimate model in type 1 diabetes.

Published in:

Diabetologia, 2020, v. 63, n. 4, p. 885, doi. 10.1007/s00125-020-05088-6

By:

Wentworth, John M.;
Bediaga, Naiara G.;
Gitelman, Stephen E.;
Evans-Molina, Carmela;
Gottlieb, Peter A.;
Colman, Peter G.;
Haller, Michael J.;
Harrison, Leonard C.

Publication type:

Article

Beta cell function in type 1 diabetes determined from clinical and fasting biochemical variables.

Published in:

Diabetologia, 2019, v. 62, n. 1, p. 33, doi. 10.1007/s00125-018-4722-z

By:

Wentworth, John M.;
Bediaga, Naiara G.;
Giles, Lynne C.;
Ehlers, Mario;
Gitelman, Stephen E.;
Geyer, Susan;
Evans-Molina, Carmella;
Harrison, Leonard C.;
the Type 1 Diabetes TrialNet Study Group;
the Immune Tolerance Network Study Group

Publication type:

Article

Distinct Gut Virome Profile of Pregnant Women With Type 1 Diabetes in the ENDIA Study.

Published in:

Open Forum Infectious Diseases, 2019, v. 6, n. 2, p. N.PAG, doi. 10.1093/ofid/ofz025

By:

Kim, Ki Wook;
Allen, Digby W;
Briese, Thomas;
Couper, Jennifer J;
Barry, Simon C;
Colman, Peter G;
Cotterill, Andrew M;
Davis, Elizabeth A;
Giles, Lynne C;
Harrison, Leonard C;
Harris, Mark;
Haynes, Aveni;
Horton, Jessica L;
Isaacs, Sonia R;
Jain, Komal;
Lipkin, Walter Ian;
Morahan, Grant;
Morbey, Claire;
Pang, Ignatius C N;
Papenfuss, Anthony T

Publication type:

Article

Protocol for a nested case-control study design for omics investigations in the Environmental Determinants of Islet Autoimmunity cohort.

Published in:

Annals of Medicine, 2023, v. 55, n. 1, p. 1, doi. 10.1080/07853890.2023.2198255

By:

Oakey, Helena;
Giles, Lynne C.;
Thomson, Rebecca L.;
Lê Cao, Kim-Anh;
Ashwood, Pat;
Brown, James D.;
Knight, Emma J.;
Barry, Simon C.;
Craig, Maria E.;
Colman, Peter G.;
Davis, Elizabeth A.;
Hamilton-Williams, Emma E.;
Harrison, Leonard C.;
Haynes, Aveni;
Kim, Ki Wook;
Mallitt, Kylie-Ann;
McGorm, Kelly;
Morahan, Grant;
Rawlinson, William D.;
Sinnott, Richard O.

Publication type:

Article

Strategies for Identifying and Predicting Islet Autoantigen T-cell Epitopes in Insulin-dependent Diabetes Mellitus.

Published in:

Annals of Medicine, 1997, v. 29, n. 5, p. 401, doi. 10.3109/07853899708999369

By:

Honeyman, Margo C.;
Brusic, Vladimir;
Harrison, Leonard C.

Publication type:

Article

Rotavirus Infection Induces Transient Pancreatic Involution and Hyperglycemia in Weanling Mice.

Published in:

PLoS ONE, 2014, v. 9, n. 9, p. 1, doi. 10.1371/journal.pone.0106560

By:

Honeyman, Margo C.;
Laine, David;
Zhan, Yifan;
Londrigan, Sarah;
Kirkwood, Carl;
Harrison, Leonard C.

Publication type:

Article

An Antibody-Based Leukocyte-Capture Microarray for the Diagnosis of Systemic Lupus Erythematosus.

Published in:

PLoS ONE, 2013, v. 8, n. 3, p. 1, doi. 10.1371/journal.pone.0058199

By:

Lin, Ming-Wei;
Ho, Joshua W. K.;
Harrison, Leonard C.;
dos Remedios, Cristobal G.;
Adelstein, Stephen

Publication type:

Article

Adult Pancreas Side Population Cells Expand after β Cell Injury and Are a Source of Insulin-Secreting Cells.

Published in:

PLoS ONE, 2012, v. 7, n. 11, p. 1, doi. 10.1371/journal.pone.0048977

By:

Banakh, Ilia;
Gonez, Leonel J.;
Sutherland, Robyn M.;
Naselli, Gaetano;
Harrison, Leonard C.

Publication type:

Article

Dominance of cytokine- over FasL-induced impairment of the mitochondrial transmembrane potential (ΔΨm) in the pancreatic β-cell line NIT-1.

Published in:

Diabetes & Vascular Disease Research, 2008, v. 5, n. 3, p. 198, doi. 10.3132/dvdr.2008.032

By:

Augstein, Petra;
Heinke, Peter;
Salzsieder, Eckhard;
Grimm, Rita;
Giebel, Jürgen;
Salzsieder, Christel;
Harrison, Leonard C

Publication type:

Article

Evidence from twins for acquired cellular immune hyperactivity in type 1 diabetes.

Published in:

Immunology, 2002, v. 106, n. 4, p. 584, doi. 10.1046/j.1365-2567.2002.01449.x

By:

Petrovsky, Nikolai;
Kyvik, Kirsten O.;
Bonnevie-Nielsen, Vagn;
Beck-Nielsen, Henning;
Green, Anders;
Harrison, Leonard C.

Publication type:

Article

Autoimmune diabetes is suppressed by transfer of proinsulin-encoding Gr-1+ myeloid progenitor cells that differentiate in vivo into resting dendritic cells.

Published in:

2005

By:

Steptoe, Raymond J.;
Ritchie, Janine M.;
Jones, Lynelle K.;
Harrison, Leonard C.

Publication type:

journal article

Guidelines for intervention trials in subjects with newly diagnosed type 1 diabetes.

Published in:

2003

By:

Greenbaum, Carla J.;
Harrison, Leonard C.;
Immunology of Diabetes Society

Publication type:

journal article

Report from the 1st International NOD Mouse T-Cell Workshop and the follow-up mini-workshop.

Published in:

2001

By:

Kaufman, Daniel L.;
Tisch, Roland;
Sarvetnick, Nora;
Chatenoud, Lucienne;
Harrison, Leonard C.;
Haskins, Kathryn;
Quinn, Anthony;
Sercarz, Eli;
Kaufman, D L;
Tisch, R;
Sarvetnick, N;
Chatenoud, L;
Harrison, L C;
Haskins, K;
Quinn, A;
Sercarz, E;
Singh, B;
von Herrath, M;
Wegmann, D;
Wen, L

Publication type:

journal article

Association between rotavirus infection and pancreatic islet autoimmunity in children at risk of developing type 1 diabetes.

Published in:

2000

By:

Honeyman, Margo C.;
Coulson, Barbara S.;
Stone, Natalie L.;
Gellert, Shane A.;
Goldwater, Paul N.;
Steele, Cheryl E.;
Couper, Jennifer J.;
Tait, Brian D.;
Colman, Peter G.;
Harrison, Leonard C.;
Honeyman, M C;
Coulson, B S;
Stone, N L;
Gellert, S A;
Goldwater, P N;
Steele, C E;
Couper, J J;
Tait, B D;
Colman, P G;
Harrison, L C

Publication type:

journal article

Lack of Association Between Duration of Breast-Feeding or Introduction of Cow's Milk and Development of Islet Autoimmunity.

Published in:

Diabetes, 1999, v. 48, n. 11, p. 2145, doi. 10.2337/diabetes.48.11.2145

By:

Couper, Jennifer J.;
Steele, Cheryl;
Beresford, Sarah;
Powell, Tania;
McCaul, Kieran;
Pollard, Angie;
Gellert, Shane;
Tait, Brian;
Harrison, Leonard C.;
Colman, Peter G.

Publication type:

Article

Cow's Milk and Type 1 Diabetes.

Published in:

Diabetes, 1999, v. 48, n. 8, p. 1501, doi. 10.2337/diabetes.48.8.1501

By:

Harrison, Leonard C.;
Honeyman, Margo C.

Publication type:

Article

Laminin-1 promotes differentiation of fetal mouse pancreatic beta-cells.

Published in:

1999

By:

Jiang, Fang-Xu;
Cram, David S.;
De-Aizpurua, Henry J.;
Harrison, Leonard C.;
Jiang, F X;
Cram, D S;
DeAizpurua, H J;
Harrison, L C

Publication type:

journal article

Transgenic Expression of Mouse Proinsulin II Prevents Diabetes in Nonobese Diabetic Mice.

Published in:

Diabetes, 1997, v. 46, n. 1, p. 34, doi. 10.2337/diab.46.1.34

By:

French, Michelle B.;
Allison, Janette;
Cram, David S.;
Thomas, Helen E.;
Dempsey-Collier, Majella;
Silva, Anabel;
Georgiou, Harry M.;
Kay, Thomas W.;
Harrison, Leonard C.;
Lew, Andrew M.

Publication type:

Article

High level of concordance between assays for glutamic acid decarboxylase antibodies. The First International Glutamic Acid Decarboxylase Antibody Workshop.

Published in:

1994

By:

Schmidli, Robert S.;
Colman, Peter G.;
Bonifacio, Ezio;
Bottazzo, Gian Franco;
Harrison, Leonard C.;
Schmidli, R S;
Colman, P G;
Bonifacio, E;
Bottazzo, G F;
Harrison, L C

Publication type:

journal article

Transcription factor jun-B is target of autoreactive T-cells in IDDM.

Published in:

1993

By:

Honeyman, Margo C.;
Cram, David S.;
Harrison, Leonard C.;
Honeyman, M C;
Cram, D S;
Harrison, L C

Publication type:

journal article

An ELISA for antibodies to recombinant glutamic acid decarboxylase in IDDM.

Published in:

1992

By:

Deaizpurua, Henry J.;
Harrison, Leonard C.;
Cram, David S.;
DeAizpurua, H J;
Harrison, L C;
Cram, D S

Publication type:

journal article

Reactivity to human islets and fetal pig proislets by peripheral blood mononuclear cells from subjects with preclinical and clinical insulin-dependent diabetes.

Published in:

1991

By:

Harrison, Leonard C.;
De Aizpurua, Henry;
Loudovaris, Thomas;
Campbell, Iain L.;
Cebon, Jonathan S.;
Tait, Brian D.;
Colman, Peter G.;
Harrison, L C;
De Aizpurua, H;
Loudovaris, T;
Campbell, I L;
Cebon, J S;
Tait, B D;
Colman, P G

Publication type:

journal article

MHC Molecules and β-Cell Destruction.

Published in:

Diabetes, 1989, v. 38, n. 7, p. 815, doi. 10.2337/diab.38.7.815

By:

Harrison, Leonard C.;
Campbell, Lain L.;
Allison, J.;
Miller, J. F. A. P.

Publication type:

Article

Double-blind controlled trial of azathioprine in children with newly diagnosed type I diabetes.

Published in:

1989

By:

Cook, Jennifer J.;
Hudson, Irene;
Harrison, Leonard C.;
Dean, Brian;
Colman, Peter G.;
Werther, George A.;
Warne, Garry L.;
Court, John M.;
Cook, J J;
Hudson, I;
Harrison, L C;
Dean, B;
Colman, P G;
Werther, G A;
Warne, G L;
Court, J M

Publication type:

journal article

Association of HLA-DQw3 (TA10-) with type I diabetes occurs with DR3/4 but not DR1/4 patients.

Published in:

1988

By:

Tait, Brian D.;
Mraz, Grant;
Harrison, Leonard C.;
Tait, B D;
Mraz, G;
Harrison, L C

Publication type:

journal article

Reovirus infection enhances expression of class I MHC proteins on human beta-cell and rat RINm5F cell.

Published in:

1988

By:

Campbell, Lain L.;
Harrison, Leonard C.;
Ashcroft, Robert G.;
Jack, Ian;
Campbell, I L;
Harrison, L C;
Ashcroft, R G;
Jack, I

Publication type:

journal article

64,000-Mr autoantigen in type I diabetes. Evidence against its surface location on human islets.

Published in:

1987

By:

Colman, Peter G.;
Campbell, Iain L.;
Kay, Thomas W. H.;
Harrison, Leonard C.;
Colman, P G;
Campbell, I L;
Kay, T W;
Harrison, L C

Publication type:

journal article

Increase in remission rate in newly diagnosed type I diabetic subjects treated with azathioprine.

Published in:

1985

By:

Harrison, Leonard C.;
Colman, Peter G.;
Dean, Brian;
Baxter, Royce;
Martin, F. I. R.;
Harrison, L C;
Colman, P G;
Dean, B;
Baxter, R;
Martin, F I

Publication type:

journal article

Interferon-γ Enhances the Expression of the Major Histocompatibility Class I Antigens on Mouse Pancreatic Beta Cells.

Published in:

Diabetes, 1985, v. 34, n. 11, p. 1205, doi. 10.2337/diab.34.11.1205

By:

Campbell, Iain L.;
Wong, Grace H. W.;
Schrader, John W.;
Harrison, Leonard C.

Publication type:

Article

Progenitor cells in the adult pancreas.

Published in:

Diabetes/Metabolism Research & Reviews, 2004, v. 20, n. 1, p. 13, doi. 10.1002/dmrr.430

By:

Andrew M. Holland;
L. Jorge Góñez;
Leonard C. Harrison

Publication type:

Article

Dietary patterns during pregnancy and maternal and birth outcomes in women with type 1 diabetes: the Environmental Determinants of Islet Autoimmunity (ENDIA) study.

Published in:

Diabetologia, 2024, v. 67, n. 11, p. 2420, doi. 10.1007/s00125-024-06259-5

By:

Thomson, Rebecca L.;
Brown, James D.;
Oakey, Helena;
Palmer, Kirsten;
Ashwood, Pat;
Penno, Megan A. S.;
McGorm, Kelly J.;
Battersby, Rachel;
Colman, Peter G.;
Craig, Maria E.;
Davis, Elizabeth A.;
Huynh, Tony;
Harrison, Leonard C.;
Haynes, Aveni;
Sinnott, Richard O.;
Vuillermin, Peter J.;
Wentworth, John M.;
Soldatos, Georgia;
Couper, Jennifer J.

Publication type:

Article

Anti- CD2 producing pig xenografts effect localized depletion of human T cells in a hu SCID model.

Published in:

Xenotransplantation, 2013, v. 20, n. 2, p. 100, doi. 10.1111/xen.12025

By:

Brady, Jamie L.;
Sutherland, Robyn M.;
Hancock, Manuela;
Kitsoulis, Susie;
Lahoud, Mireille H.;
Phillips, Peta M.;
Hawthorne, Wayne J.;
d'Apice, Anthony J. F.;
Cowan, Peter J.;
Harrison, Leonard C.;
O'Connell, Philip J.;
Lew, Andrew M.

Publication type:

Article

High avidity antibodies to fetal pig pancreas endocrine cells transfer rejection but are not normally generated to fetal pig pancreas xenografts.

Published in:

Xenotransplantation, 2002, v. 9, n. 6, p. 382, doi. 10.1034/j.1399-3089.2002.01008.x

By:

Fox, Annette;
Mountford, Joanne;
Braakhuis, Andrea;
Harrison, Leonard C

Publication type:

Article

Decreased occurrence of ketoacidosis and preservation of beta cell function in relatives screened and monitored for type 1 diabetes in Australia and New Zealand.

Published in:

Pediatric Diabetes, 2022, v. 23, n. 8, p. 1594, doi. 10.1111/pedi.13422

By:

Wentworth, John M.;
Oakey, Helena;
Craig, Maria E.;
Couper, Jennifer J.;
Cameron, Fergus J.;
Davis, Elizabeth A.;
Lafferty, Antony R.;
Harris, Mark;
Wheeler, Benjamin J.;
Jefferies, Craig;
Colman, Peter G.;
Harrison, Leonard C.

Publication type:

Article

Associations between diet, the gut microbiome and short chain fatty acids in youth with islet autoimmunity and type 1 diabetes.

Published in:

Pediatric Diabetes, 2021, v. 22, n. 3, p. 425, doi. 10.1111/pedi.13178

By:

Harbison, Jessica E.;
Thomson, Rebecca L.;
Wentworth, John M.;
Louise, Jennie;
Roth‐Schulze, Alexandra;
Battersby, Rachel J.;
Ngui, Katrina M.;
Penno, Megan A. S.;
Colman, Peter G.;
Craig, Maria E.;
Barry, Simon C.;
Tran, Cuong D.;
Makrides, Maria;
Harrison, Leonard C.;
Couper, Jennifer J.

Publication type:

Article

Higher frequency of vertebrate‐infecting viruses in the gut of infants born to mothers with type 1 diabetes.

Published in:

Pediatric Diabetes, 2020, v. 21, n. 2, p. 271, doi. 10.1111/pedi.12952

By:

Kim, Ki Wook;
Allen, Digby W.;
Briese, Thomas;
Couper, Jennifer J.;
Barry, Simon C.;
Colman, Peter G.;
Cotterill, Andrew M.;
Davis, Elizabeth A.;
Giles, Lynne C.;
Harrison, Leonard C.;
Harris, Mark;
Haynes, Aveni;
Horton, Jessica L.;
Isaacs, Sonia R.;
Jain, Komal;
Lipkin, Walter I.;
McGorm, Kelly;
Morahan, Grant;
Morbey, Claire;
Pang, Ignatius C. N.

Publication type:

Article

Gut microbiome dysbiosis and increased intestinal permeability in children with islet autoimmunity and type 1 diabetes: A prospective cohort study.

Published in:

Pediatric Diabetes, 2019, v. 20, n. 5, p. 574, doi. 10.1111/pedi.12865

By:

Harbison, Jessica E.;
Roth‐Schulze, Alexandra J.;
Giles, Lynne C.;
Tran, Cuong D.;
Ngui, Katrina M.;
Penno, Megan A.;
Thomson, Rebecca L.;
Wentworth, John M.;
Colman, Peter G.;
Craig, Maria E.;
Morahan, Grant;
Papenfuss, Anthony T.;
Barry, Simon C.;
Harrison, Leonard C.;
Couper, Jennifer J.

Publication type:

Article

Type 1 diabetes: a disease of developmental origins.

Published in:

Pediatric Diabetes, 2017, v. 18, n. 6, p. 417, doi. 10.1111/pedi.12425

By:

Phillips, Jessica E.;
Couper, Jennifer J.;
Penno, Megan A.S.;
Harrison, Leonard C.;
Anderson, Heather;
Bandala‐Sanchez, Esther;
Barry, Simon C;
Baskerville, Tracey;
Battersby, Rachel;
Bediaga, Naiara G;
Bezuidenhout, Debra;
Brownrigg, Emma;
Catteau, Jacki;
Choo, Ace;
Colman, Peter G;
Cotterill, Andrew;
Couper, Jennifer J;
Craig, Maria E;
Curran, Sheryl;
Davis, Elizabeth A

Publication type:

Article

Persistently autoantibody-negative type 1 diabetes: Rich pickings or much ado about nothing?

Published in:

Pediatric Diabetes, 2011, v. 12, n. 3pt1, p. 139, doi. 10.1111/j.1399-5448.2011.00786.x

By:

Harrison, Leonard C.

Publication type:

Article

Insulin resistance in children and adolescents with type 1 diabetes mellitus: relation to obesity.

Published in:

2005

By:

Fourlanos, Spiros;
Harrison, Leonard C.

Publication type:

Editorial