Found: 38
Select item for more details and to access through your institution.
A Protein Aggregation Inhibitor, Leuco-Methylthioninium Bis(Hydromethanesulfonate), Decreases α-Synuclein Inclusions in a Transgenic Mouse Model of Synucleinopathy.
- Published in:
- Frontiers in Molecular Neuroscience, 2018, p. 1, doi. 10.3389/fnmol.2017.00447
- By:
- Publication type:
- Article
Reduction in tau‐pathology induced with two novel tau aggregation inhibitors in Alzheimer mice.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, n. 21, p. 1, doi. 10.1002/alz.076607
- By:
- Publication type:
- Article
Back‐translation of clinical tau‐aggregation inhibitor trials to experimental models: negative interactions of dementia therapies.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076153
- By:
- Publication type:
- Article
The AβpE 3‐42 peptide is associated with a higher degree of inflammation than Aβ1‐40 in brains with Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077583
- By:
- Publication type:
- Article
The AβpE 3‐42 peptide is associated with a higher degree of inflammation than Aβ1‐40 in brains with Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077583
- By:
- Publication type:
- Article
Neurovascular unit dysfunction in Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.050442
- By:
- Publication type:
- Article
Insoluble Vascular Amyloid Deposits Trigger Disruption of the Neurovascular Unit in Alzheimer's Disease Brains.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 7, p. 3654, doi. 10.3390/ijms22073654
- By:
- Publication type:
- Article
The Neurovascular Unit Dysfunction in Alzheimer's Disease.
- Published in:
- International Journal of Molecular Sciences, 2021, v. 22, n. 4, p. 2022, doi. 10.3390/ijms22042022
- By:
- Publication type:
- Article
Current Progress and Future Directions for Tau-Based Fluid Biomarker Diagnostics in Alzheimer's Disease.
- Published in:
- International Journal of Molecular Sciences, 2020, v. 21, n. 22, p. 8673, doi. 10.3390/ijms21228673
- By:
- Publication type:
- Article
LMTM DECREASES α-SYNUCLEIN PATHOLOGY AND REDUCES BEHAVIOURAL DEFECTS IN α-SYNUCLEIN TRANSGENIC MICE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2017, v. 13, p. P945, doi. 10.1016/j.jalz.2017.06.1854
- By:
- Publication type:
- Article
PHASE 3 TRIAL OF THE TAU AGGREGATION INHIBITOR LEUCO-METHYLTHIONINIUM-BIS (HYDROMETHANESULFONATE) (LMTM) IN MILD TO MODERATE ALZHEIMER'S DISEASE.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2016, v. 12, p. P351, doi. 10.1016/j.jalz.2016.06.650
- By:
- Publication type:
- Article
Hyperphosphorylation along the C-terminal of tau protein is associated with PHF assembly resulting from truncation at Glu-391, in AlzheimerÂś disease
- Published in:
- 2011
- By:
- Publication type:
- Abstract
Overexpression of mutant tau in mice leads to tau aggregation and deterioration of motor skills
- Published in:
- 2009
- By:
- Publication type:
- Abstract
Age-related impairments in tau transgenic mice using two different water maze training protocols
- Published in:
- 2009
- By:
- Publication type:
- Abstract
P2-383: Reversal of spatial problem-solving cognitive deficit in a transgenic mouse line overexpressing the repeat domain of Tau by treatment with the Tau aggregation inhibitor methylthioninium chloride
- Published in:
- 2008
- By:
- Publication type:
- Abstract
P1-109: Subtle behavioural changes in transgenic mice with amorphous Tau aggregates
- Published in:
- 2008
- By:
- Publication type:
- Abstract
P1-054: Early and advanced stages of Tau aggregation in transgenic mouse models
- Published in:
- 2008
- By:
- Publication type:
- Abstract
A glycation connection.
- Published in:
- Nature, 1994, v. 370, n. 6487, p. 247, doi. 10.1038/370247a0
- By:
- Publication type:
- Article
Hydromethylthionine enhancement of central cholinergic signalling is blocked by rivastigmine and memantine.
- Published in:
- Journal of Neurochemistry, 2022, v. 160, n. 2, p. 172, doi. 10.1111/jnc.15553
- By:
- Publication type:
- Article
Absence of a Role for Phosphorylation in the Tau Pathology of Alzheimer's Disease.
- Published in:
- Biomolecules (2218-273X), 2016, v. 6, n. 2, p. 19, doi. 10.3390/biom6020019
- By:
- Publication type:
- Article
The relationship between truncation and phosphorylation at the C-terminus of tau protein in the paired helical filaments of Alzheimer's disease.
- Published in:
- Frontiers in Neuroscience, 2015, v. 9, p. 1, doi. 10.3389/fnins.2015.00033
- By:
- Publication type:
- Article
Thiazin red as a neuropathological tool for the rapid diagnosis of Alzheimer’s disease in tissue imprints.
- Published in:
- Acta Neuropathologica, 2008, v. 116, n. 5, p. 507, doi. 10.1007/s00401-008-0431-x
- By:
- Publication type:
- Article
Staging the pathological assembly of truncated tau protein into paired helical filaments in Alzheimer's disease.
- Published in:
- Acta Neuropathologica, 1996, v. 91, n. 6, p. 633, doi. 10.1007/s004010050477
- By:
- Publication type:
- Article
Solid-state NMR of paired helical filaments formed by the core tau fragment tau(297-391).
- Published in:
- Frontiers in Neuroscience, 2022, v. 16, p. 1, doi. 10.3389/fnins.2022.988074
- By:
- Publication type:
- Article
Degeneration of basal and limbic networks is a core feature of behavioural variant frontotemporal dementia.
- Published in:
- Brain Communications, 2021, v. 3, n. 4, p. 1, doi. 10.1093/braincomms/fcab241
- By:
- Publication type:
- Article
Elucidating the Neuropathologic Mechanisms of SARS-CoV-2 Infection.
- Published in:
- Frontiers in Neurology, 2021, v. 11, p. N.PAG, doi. 10.3389/fneur.2021.660087
- By:
- Publication type:
- Article
HMTM-Mediated Enhancement of Brain Bioenergetics in a Mouse Tauopathy Model Is Blocked by Chronic Administration of Rivastigmine.
- Published in:
- Biomedicines, 2022, v. 10, n. 4, p. 867, doi. 10.3390/biomedicines10040867
- By:
- Publication type:
- Article
Neuroprotection of Cholinergic Neurons with a Tau Aggregation Inhibitor and Rivastigmine in an Alzheimer's-like Tauopathy Mouse Model.
- Published in:
- Cells (2073-4409), 2024, v. 13, n. 7, p. 642, doi. 10.3390/cells13070642
- By:
- Publication type:
- Article
Utility of Blood-Based Tau Biomarkers for Mild Cognitive Impairment and Alzheimer's Disease: Systematic Review and Meta-Analysis.
- Published in:
- Cells (2073-4409), 2023, v. 12, n. 8, p. 1184, doi. 10.3390/cells12081184
- By:
- Publication type:
- Article
Proteomic Analysis of Hydromethylthionine in the Line 66 Model of Frontotemporal Dementia Demonstrates Actions on Tau-Dependent and Tau-Independent Networks.
- Published in:
- Cells (2073-4409), 2021, v. 10, n. 8, p. 2162, doi. 10.3390/cells10082162
- By:
- Publication type:
- Article
Oxidative Stress Conditions Result in Trapping of PHF-Core Tau (297–391) Intermediates.
- Published in:
- Cells (2073-4409), 2021, v. 10, n. 3, p. 703, doi. 10.3390/cells10030703
- By:
- Publication type:
- Article
High-affinity antibodies specific to the core region of the tau protein exhibit diagnostic and therapeutic potential for Alzheimer's disease.
- Published in:
- Alzheimer's Research & Therapy, 2024, v. 16, n. 1, p. 1, doi. 10.1186/s13195-024-01561-1
- By:
- Publication type:
- Article
Tau (297‐391) forms filaments that structurally mimic the core of paired helical filaments in Alzheimer's disease brain.
- Published in:
- FEBS Letters, 2020, v. 594, n. 5, p. 944, doi. 10.1002/1873-3468.13675
- By:
- Publication type:
- Article
Considerations for biomarker strategies in clinical trials investigating tau-targeting therapeutics for Alzheimer's disease.
- Published in:
- Translational Neurodegeneration, 2024, v. 13, n. 1, p. 1, doi. 10.1186/s40035-024-00417-w
- By:
- Publication type:
- Article
PHF-Core Tau as the Potential Initiating Event for Tau Pathology in Alzheimer's Disease.
- Published in:
- Frontiers in Cellular Neuroscience, 2020, v. 14, p. N.PAG, doi. 10.3389/fncel.2020.00247
- By:
- Publication type:
- Article
Exploring the Anti-Hypoxaemia Effect of Hydromethylthionine: A Prospective Study of Phase 3 Clinical Trial Participants.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 18, p. 13747, doi. 10.3390/ijms241813747
- By:
- Publication type:
- Article
Mitochondrial Effects of Hydromethylthionine, Rivastigmine and Memantine in Tau-Transgenic Mice.
- Published in:
- International Journal of Molecular Sciences, 2023, v. 24, n. 13, p. 10810, doi. 10.3390/ijms241310810
- By:
- Publication type:
- Article
Solubility of α-synuclein species in the L62 mouse model of synucleinopathy.
- Published in:
- Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-56735-6
- By:
- Publication type:
- Article