Works matching AU Harmatz, Jerold S

Results: 112

Alprazolam Metabolism in vitro: Studies of Human, Monkey, Mouse, and Rat Liver Microsomes.

Published in:

Pharmacology, 1993, v. 47, n. 4, p. 268, doi. 10.1159/000139107

By:

von Moltke, Lisa L.;
Greenblatt, David J.;
Harmatz, Jerold S.;
Shader, Richard I.

Publication type:

Article

Differential Effect of Cigarette Smoking on Antipyrine Oxidation versus Acetaminophen Conjugation.

Published in:

Pharmacology, 1990, v. 40, n. 2, p. 77, doi. 10.1159/000138644

By:

Scavone, Joseph M.;
Greenblatt, David J.;
LeDuc, Barbara W.;
Blyden, Gershwin T.;
Luna, Becki G.;
Harmatz, Jerold S.

Publication type:

Article

Age and Gender Effects on Chlordiazepoxide Kinetics: Relation to Antipyrine Disposition.

Published in:

Pharmacology, 1989, v. 38, n. 5, p. 327, doi. 10.1159/000138553

By:

Greenblatt, David J.;
Divoll, Marcia K.;
Abernethy, Darrell R.;
Ochs, Hermann R.;
Harmatz, Jerold S.;
Shader, Richard I.

Publication type:

Article

Antipyrine Absorption and Disposition in the Elderly.

Published in:

Pharmacology, 1988, v. 36, n. 2, p. 125, doi. 10.1159/000138369

By:

Greenblatt, David J.;
Divoll, Marcia K.;
Harmatz, Jerold S.;
Shader, Richard I.

Publication type:

Article

Serum Digoxin Concentrations and Subjective Manifestations of Toxicity.

Published in:

Pharmacology, 1980, v. 20, n. 3, p. 149, doi. 10.1159/000137358

By:

Ochs, Hermann R.;
Greenblatt, David J.;
Harmatz, Jerold S.;
Bodem, Gunther

Publication type:

Article

Sex Differences in Diazepam Protein Binding in Patients with Renal Insufficiency.

Published in:

Pharmacology, 1978, v. 16, n. 1, p. 26, doi. 10.1159/000136742

By:

Greenblatt, David J.;
Harmatz, Jerold S.;
Shader, Richard I.

Publication type:

Article

Clinical Consequences of Altered Drug Disposition in Obesity: Call for Change.

Published in:

Journal of Clinical Pharmacology, 2023, v. 63, p. S25, doi. 10.1002/jcph.2308

By:

Bruno, Christopher D.;
Greenblatt, David J.;
Harmatz, Jerold S.;
Chow, Christina R.

Publication type:

Article

Estimation of Absolute and Relative Body Fat Content Using Noninvasive Surrogates: Can DXA Be Bypassed?

Published in:

Journal of Clinical Pharmacology, 2023, v. 63, p. S35, doi. 10.1002/jcph.2306

By:

Greenblatt, David J.;
Bruno, Christopher D.;
Harmatz, Jerold S.;
Dawson‐Hughes, Bess;
Zhang, Qingchen;
Li, Chunhui;
Chow, Christina R.

Publication type:

Article

Drug Disposition in Subjects With Obesity: The Research Work of Darrell R. Abernethy.

Published in:

Journal of Clinical Pharmacology, 2022, v. 62, n. 11, p. 1350, doi. 10.1002/jcph.2093

By:

Greenblatt, David J.;
Bruno, Christopher D.;
Harmatz, Jerold S.;
Zhang, Qingchen;
Chow, Christina R.

Publication type:

Article

Slow Accumulation and Elimination of Diazepam and Its Active Metabolite With Extended Treatment in the Elderly.

Published in:

Journal of Clinical Pharmacology, 2021, v. 61, n. 2, p. 193, doi. 10.1002/jcph.1726

By:

Greenblatt, David J.;
Harmatz, Jerold S.;
Zhang, Qingchen;
Chen, Yuxi;
Shader, Richard I.

Publication type:

Article

Persistence of a Posaconazole‐Mediated Drug‐Drug Interaction With Ranolazine After Cessation of Posaconazole Administration: Impact of Obesity and Implications for Patient Safety.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 11, p. 1436, doi. 10.1002/jcph.1257

By:

Chow, Christina R.;
Harmatz, Jerold S.;
Ryan, Michael J.;
Greenblatt, David J.

Publication type:

Article

Molecular and Pharmacokinetic Evaluation of Rat Hepatic and Gastrointestinal Cytochrome P450 Induction by Tamoxifen.

Published in:

Pharmacology, 2001, v. 63, n. 4, p. 210, doi. 10.1159/000056136

By:

Cotreau, Monette M.;
von Moltke, Lisa L.;
Harmatz, Jerold S.;
Greenblatt, David J.

Publication type:

Article

Characterization of Six in vitro Reactions Mediated by Human Cytochrome P450: Application to the Testing of Cytochrome P450-Directed Antibodies.

Published in:

Pharmacology, 1996, v. 52, n. 2, p. 125, doi. 10.1159/000139376

By:

Schmider, Jürgen;
Greenblatt, David J.;
von Moltke, Lisa L.;
Harmatz, Jerold S.;
Duan, Su X.;
Karsov, Dmitry;
Shader, Richard I.

Publication type:

Article

EXTRAPOLATING IN VITRO DATA ON DRUG METABOLISM TO IN VIVO PHARMACOKINETICS: EVALUATION OF THE PHARMACOKINETIC INTERACTION BETWEEN AMITRIPTYLINE AND FLUOXETINE.

Published in:

Drug Metabolism Reviews, 1999, v. 31, n. 2, p. 545, doi. 10.1081/DMR-100101935

By:

SCHMIDER, JÜRGEN;
VON MOLTKE, LISA L.;
SHADER, RICHARD I.;
HARMATZ, JEROLD S.;
GREENBLATT, DAVID J.

Publication type:

Article

Nefazodone, meta-chlorophenylpiperazine, and their metabolites in vitro: cytochromes mediating transformation, and P450-3A4 inhibitory actions.

Published in:

Psychopharmacology, 1999, v. 145, n. 1, p. 113, doi. 10.1007/s002130051039

By:

von Moltke, Lisa L.;
Greenblatt, David J.;
Granda, Brian W.;
Grassi, Jeffrey M.;
Schmider, Jürgen;
Harmatz, Jerold S.;
Shader, Richard I.;
von Moltke, L. L.

Publication type:

Article

Human cytochromes mediating N-demethylation of fluoxetine in vitro.

Published in:

Psychopharmacology, 1997, v. 132, n. 4, p. 402, doi. 10.1007/s002130050362

By:

von Moltke, L. L.;
Greenblatt, David J.;
Duan, Su Xiang;
Schmider, Jürgen;
Wright, C. Eugene;
Harmatz, Jerold S.;
Shader, Richard I.;
Moltke, L. L. Von

Publication type:

Article

Phenacetin O-deethylation by human liver microsomes in vitro: inhibition by chemical probes, SSRI antidepressants, nefazodone and venlafaxine.

Published in:

Psychopharmacology, 1996, v. 128, n. 4, p. 398, doi. 10.1007/s002130050149

By:

von Moltke, L. L.;
Greenblatt, David J.;
Duan, Su Xiang;
Schmider, Jürgen;
Kudchadker, Leena;
Fogelman, Steven M.;
Harmatz, Jerold S.;
Shader, Richard I.

Publication type:

Article

Impaired Rivaroxaban Clearance in Mild Renal Insufficiency With Verapamil Coadministration: Potential Implications for Bleeding Risk and Dose Selection.

Published in:

Journal of Clinical Pharmacology, 2018, v. 58, n. 4, p. 533, doi. 10.1002/jcph.1040

By:

Greenblatt, David J.;
Patel, Maulik;
Harmatz, Jerold S.;
Nicholson, Wayne T.;
Rubino, Christopher M.;
Chow, Christina R.

Publication type:

Article

Systemic Pharmacokinetics and Cerebrospinal Fluid Uptake of Intravenous Ceftriaxone in Patients With Amyotrophic Lateral Sclerosis.

Published in:

Journal of Clinical Pharmacology, 2014, v. 54, n. 10, p. 1180, doi. 10.1002/jcph.317

By:

Zhao, Yanli;
Cudkowicz, Merit E.;
Shefner§, Jeremy M.;
Krivickas, Lisa;
David, William S.;
Vriesendorp, Francine;
Pestronk, Alan;
Caress, James B.;
Katz, Jonathan;
Simpson, Ericka;
Rosenfeld, Jeffrey;
Pascuzzi, Robert;
Glass, Jonathan;
Rezania, Kourosh;
Harmatz, Jerold S.;
Schoenfeld, David;
Greenblatt, David J.

Publication type:

Article

Gender differences in pharmacokinetics and pharmacodynamics of zolpidem following sublingual administration.

Published in:

Journal of Clinical Pharmacology, 2014, v. 54, n. 3, p. 282, doi. 10.1002/jcph.220

By:

Greenblatt, David J.;
Harmatz, Jerold S.;
Singh, Nikhilesh N.;
Steinberg, Frank;
Roth, Thomas;
Moline, Margaret L.;
Harris, Stephen C.;
Kapil, Ram P.

Publication type:

Article

Influence of food on pharmacokinetics of zolpidem from fast dissolving sublingual zolpidem tartrate tablets.

Published in:

Journal of Clinical Pharmacology, 2013, v. 53, n. 11, p. 1194, doi. 10.1002/jcph.159

By:

Greenblatt, David J.;
Harmatz, Jerold S.;
Singh, Nikhilesh N.;
Roth, Thomas;
Harris, Stephen C.;
Kapil, Ram P.

Publication type:

Article

The Absence of an Interaction Between Warfarin and Cranberry Juice: A Randomized, Double-Blind Trial.

Published in:

Journal of Clinical Pharmacology, 2009, v. 49, n. 7, p. 824, doi. 10.1177/0091270009337510

By:

Ansell, Jack;
McDonough, Maryellen;
Yanli Zhao;
Harmatz, Jerold S.;
Greenblatt, David J.

Publication type:

Article

Dynamics and Kinetics of a Modified-Release Formulation of Zolpidem: Comparison With Immediate-Release Standard Zolpidem and Placebo.

Published in:

Journal of Clinical Pharmacology, 2006, v. 46, n. 12, p. 1469, doi. 10.1177/0091270006293303

By:

Greenblatt, David J.;
Legangneux, Eric;
Harmatz, Jerold S.;
Weinling, Estelle;
Freeman, Jon;
Rice, Kathleen;
Zammit, Gary K.

Publication type:

Article

Ginkgo biloba Does Not Alter Clearance of Flurbiprofen, a Cytochrome P450-2C9 Substrate.

Published in:

Journal of Clinical Pharmacology, 2006, v. 46, n. 2, p. 214, doi. 10.1177/0091270005283465

By:

Greenblatt, David J.;
von Moltke, Lisa L.;
Luo, Yan;
Perloff, Elke S.;
Horan, Kelly A.;
Bruce, Allison;
Reynolds, Robyn C.;
Harmatz, Jerold S.;
Avula, Bharathi;
Khan, Ikhlas A.;
Goldman, Peter

Publication type:

Article

Clonazepam Pharmacokinetics: Comparison of Subcutaneous Microsphere Injection With Multiple-Dose Oral Administration.

Published in:

Journal of Clinical Pharmacology, 2005, v. 45, n. 11, p. 1288, doi. 10.1177/0091270005280861

By:

Greenblatt, David J.;
Blaskovich, Philip D.;
Nuwayser, E. S.;
Harmatz, Jerold S.;
Chen, Gengsheng;
Zinny, Miguel A.

Publication type:

Article

Kinetics and Dynamics of Intravenous Adinazolam, N-Desmethyl Adinazolam, and Alprazolam in Healthy Volunteers.

Published in:

Journal of Clinical Pharmacology, 2005, v. 45, n. 5, p. 529, doi. 10.1177/0091270004269105

By:

Venkatakrishnan, Karthik;
Culm, Kerry E.;
Ehrenberg, Bruce L.;
Harmatz, Jerold S.;
Corbett, Kathleen E.;
Fleishaker, Joseph C.;
Greenblatt, David J.

Publication type:

Article

Kinetics and EEG Effects of Midazolam during and after 1-Minute, 1-Hour, and 3-Hour Intravenous Infusions.

Published in:

Journal of Clinical Pharmacology, 2004, v. 44, n. 6, p. 605

By:

David J. Greenblatt;
Bruce L. Ehrenberg;
Kerry E. Culm;
Joseph M. Scavone;
Kathleen E. Corbett;
Hylar L. Friedman;
Jerold S. Harmatz;
Richard I. Shader

Publication type:

Article

Short-Term Exposure to Low-Dose Ritonavir Impairs Clearance and Enhances Adverse Effects of Trazodone.

Published in:

Journal of Clinical Pharmacology, 2003, v. 43, n. 4, p. 414

By:

David J. Greenblatt;
Lisa L. von Moltke;
Jerold S. Harmatz;
Steven M. Fogelman;
Gengsheng Chen;
Jennifer A. Graf;
Polyxane Mertzanis;
Susan Byron;
Kerry E. Culm;
Brian W. Granda;
Johanna P. Daily;
Richard I. Shader

Publication type:

Article

Zolpidem Pharmacokinetic Properties in Young Females: Influence of Smoking and Oral Contraceptive Use.

Published in:

Journal of Clinical Pharmacology, 2002, v. 42, n. 10, p. 1142, doi. 10.1177/009127002237988

By:

Olubodun, Joel O.;
Ochs, Hermann R.;
Trüten, Volker;
Klein, Arno;
von Moltke, Lisa L.;
Harmatz, Jerold S.;
Shader, Richard I.;
Greenblatt, David J.

Publication type:

Article

Relative Contribution of CYP3A to Amitriptyline Clearance in Humans: in Vitro and in Vivo Studies.

Published in:

Journal of Clinical Pharmacology, 2001, v. 41, n. 10, p. 1043, doi. 10.1177/009127000104101001

By:

Venkatakrishnan, Karthik;
Schmider, Jürgen;
Harmatz, Jerold S.;
Ehrenberg, Bruce L.;
von Moltke, Lisa L.;
Graf, Jennifer A.;
Mertzanis, Polyxane;
Corbett, Kathleen E.;
Rodriguez, Molly C.;
Shader, Richard I.;
Greenblatt, David J.

Publication type:

Article

Inhibition of Human Cytochrome P450 Isoforms by Nonnucleoside Reverse Transcriptase Inhibitors.

Published in:

Journal of Clinical Pharmacology, 2001, v. 41, n. 1, p. 85, doi. 10.1177/009127000104100i110

By:

von Moltke, Lisa L.;
Greenblatt, David J.;
Granda, Brian W.;
Giancarlo, Gina M.;
Duan, Su Xiang;
Daily, Johanna P.;
Harmatz, Jerold S.;
Shader, Richard I.

Publication type:

Article

Population Pharmacokinetics of Methylphenidate in Children with Attention-Deficit Hyperactivity Disorder.

Published in:

Journal of Clinical Pharmacology, 1999, v. 39, n. 8, p. 775, doi. 10.1177/009127009903900802

By:

Shader, Richard I.;
Harmatz, Jerold S.;
Oesterheld, Jessica R.;
Parmelee, Dean X.;
Sallee, Floyd R.;
Greenblatt, David J.

Publication type:

Article

Pharmacokinetics and Pharmacodynamics of Diphenhydramine 25 mg in Young and Elderly Volunteers.

Published in:

1998

By:

Scavone, Joseph M.;
Greenblatt, David J.;
Harmatz, Jerold S.;
Engelhardt, Nina;
Shader, Richard I.

Publication type:

Other

Five Distinct Human Cytochromes Mediate Amitriptyline N-Demethylation In Vitro: Dominance of CYP 2C19 and 3A4.

Published in:

1998

By:

Venkatakrishnan, Karthik;
Greenblatt, David J.;
Moltke, Lisa L.;
Schmider, Jürgen;
Harmatz, Jerold S.;
Shader, Richard I.

Publication type:

Other

Protease Inhibitors as Inhibitors of Human Cytochromes P450: High Risk Associated with Ritonavir.

Published in:

1998

By:

Moltke, Lisa L.;
Greenblatt, David J.;
Grassi, Jeffrey M.;
Granda, Brian W.;
Duan, Su Xiang;
Fogelman, Steven M.;
Daily, Johanna P.;
Harmatz, Jerold S.;
Shader, Richard I.

Publication type:

Other

Single-Dose Pharmacokinetics and Pharmacodynamics of Alprazolam in Elderly and Young Subjects.

Published in:

1998

By:

Kaplan, Gary B.;
Greenblatt, David J.;
Ehrenberg, Bruce L.;
Goddard, Jill E.;
Harmatz, Jerold S.;
Shader, Richard I.

Publication type:

Other

Dose-Dependent Pharmacokinetics and Psychomotor Effects of Caffeine in Humans.

Published in:

1997

By:

Kaplan, Gary B.;
Greenblatt, David J.;
Ehrenberg, Bruce L.;
Goddard, Jill E.;
Cotreau, Monette M.;
Harmatz, Jerold S.;
Shader, Richard I.

Publication type:

Other

Influence of Oral Contraceptive Use and Cigarette Smoking, Alone and Together, on Antipyrine Pharmacokinetics.

Published in:

1997

By:

Scavone, Joseph M.;
Greenblatt, David J.;
Abernethy, Darrell R.;
Luna, Becki G.;
Harmatz, Jerold S.;
Shader, Richard I.

Publication type:

Other

Inhibition of Human Cytochrome P450-3A Isoforms by Fluoxetine and Norfluoxetine: In Vitro and In Vivo Studies.

Published in:

Journal of Clinical Pharmacology, 1996, v. 36, n. 9, p. 792, doi. 10.1002/j.1552-4604.1996.tb04252.x

By:

Greenblatt, David J.;
Moltke, Lisa L.;
Schmider, Jürgen;
Harmatz, Jerold S.;
Shader, Richard I.

Publication type:

Article

Midazolam Hydroxylation by Human Liver Microsomes In Vitro: Inhibition by Fluoxetine, Norfluoxetine, and by Azole Antifungal Agents.

Published in:

1996

By:

Moltke, Lisa L.;
Greenblatt, David J.;
Schmider, Jürgen;
Duan, Su Xiang;
Wright, C. Eugene;
Harmatz, Jerold S.;
Shader, Richard I.

Publication type:

Other

Effect of extended exposure to grapefruit juice on cytochrome P450 3A activity in humans: Comparison with ritonavir*.

Published in:

Clinical Pharmacology & Therapeutics, 2006, v. 79, n. 3, p. 243, doi. 10.1016/j.clpt.2005.11.009

By:

Culm-Merdek, Kerry E.;
von Moltke, Lisa L.;
Lu Gan;
Horan, Kelly A.;
Reynolds, Robyn;
Harmatz, Jerold S.;
Court, Michael H.;
Greenblatt, David J.

Publication type:

Article

Interaction of flurbiprofen with cranberry juice, grape juice, tea, and fluconazole: In vitro and clinical studies*.

Published in:

Clinical Pharmacology & Therapeutics, 2006, v. 79, n. 1, p. 125, doi. 10.1016/j.clpt.2005.09.014

By:

Greenblatt, David J.;
von Moltke, Lisa L.;
Perloff, Elke Störmer;
Yan Luo;
Harmatz, Jerold S.;
Zinny, Miguel A.

Publication type:

Article

Age and gender effects on the pharmacokinetics and pharmacodynamics of triazolam, a cytochrome P450 3A substrate*.

Published in:

Clinical Pharmacology & Therapeutics, 2004, v. 76, n. 5, p. 467, doi. 10.1016/j.clpt.2004.07.009

By:

Greenblatt, David J.;
Harmatz, Jerold S.;
von Moltke, Lisa L.;
Wright, C. Eugene;
Shader, Richard I.

Publication type:

Article

Time course of recovery of cytochrome p450 3A function after single doses of grapefruit juice*.

Published in:

Clinical Pharmacology & Therapeutics, 2003, v. 74, n. 2, p. 121, doi. 10.1016/S0009-9236(03)00118-8

By:

Greenblatt, David J.;
von Moltke, Lisa L.;
Harmatz, Jerold S.;
Chen, Gengsheng;
Weemhoff, James L.;
Jen, Cheng;
Kelley, Charles J.;
LeDuc, Barbara W.;
Zinny, Miguel A.

Publication type:

Article

Alprazolam-ritonavir interaction: Implications for product labeling*.

Published in:

Clinical Pharmacology & Therapeutics, 2000, v. 67, n. 4, p. 335, doi. 10.1067/mcp.2000.105757

By:

Greenblatt, David J.;
von Moltke, Lisa L.;
Harmatz, Jerold S.;
Durol, Anna Liza B.;
Daily, Johanna P.;
Graf, Jennifer A.;
Mertzanis, Polyxane;
Hoffman, Jonathan L.;
Shader, Richard I.

Publication type:

Article

Kinetic and dynamic interaction study of zolpidem with ketoconazole, itraconazole, and fluconazole*.

Published in:

Clinical Pharmacology & Therapeutics, 1998, v. 64, n. 6, p. 661, doi. 10.1016/S0009-9236(98)90057-1

By:

Greenblatt, David J.;
von Moltke, Lisa L.;
Harmatz, Jerold S.;
Mertzanis, Polyxane;
Graf, Jennifer A.;
Durol, Anna Liza B.;
Counihan, Molly;
Roth-Schechter, Barbara;
Shader, Richard I.

Publication type:

Article

Comparative kinetics and dynamics of zaleplon, zolpidem, and placebo*.

Published in:

Clinical Pharmacology & Therapeutics, 1998, v. 64, n. 5, p. 553, doi. 10.1016/S0009-9236(98)90139-4

By:

Greenblatt, David J.;
Harmatz, Jerold S.;
von Moltke, Lisa L.;
Ehrenberg, Bruce L.;
Harrel, Lisa;
Corbett, Kate;
Counihan, Molly;
Graf, Jennifer A.;
Darwish, Mona;
Mertzanis, Polyxane;
Martin, Patrick T.;
Cevallos, William H.;
Shader, Richard I.

Publication type:

Article

Ketoconazole inhibition of triazolam and alprazolam clearance: Differential kinetic and dynamic consequences*.

Published in:

Clinical Pharmacology & Therapeutics, 1998, v. 64, n. 3, p. 237, doi. 10.1016/S0009-9236(98)90172-2

By:

Greenblatt, David J.;
Wright, C. Eugene;
von Moltke, Lisa L.;
Harmatz, Jerold S.;
Ehrenberg, Bruce L.;
Harrel, Lisa M.;
Corbett, Kate;
Counihan, Molly;
Tobias, Sara;
Shader, Richard I.

Publication type:

Article

Inhibition of triazolam clearance by macrolide antimicrobial agents: In vitro correlates and dynamic consequences*.

Published in:

Clinical Pharmacology & Therapeutics, 1998, v. 64, n. 3, p. 278, doi. 10.1016/S0009-9236(98)90176-X

By:

Greenblatt, David J.;
von Moltke, Lisa L.;
Harmatz, Jerold S.;
Counihan, Molly;
Graf, Jennifer A.;
Durol, Anna Liza B.;
Mertzanis, Polyxane;
Duan, Su Xiang;
Wright, C. Eugene;
Shader, Richard I.

Publication type:

Article

Effect of lipophilicity on drug distribution and elimination: Influence of obesity.

Published in:

British Journal of Clinical Pharmacology, 2021, v. 87, n. 8, p. 3197, doi. 10.1111/bcp.14735

By:

Bruno, Christopher D.;
Harmatz, Jerold S.;
Duan, Su X.;
Zhang, Qingchen;
Chow, Christina R.;
Greenblatt, David J.

Publication type:

Article