Works by Harley, John B.


Results: 116
    1

    Biology-Driven Gene-Gene Interaction Analysis of Age-Related Cataract in the eMERGE Network.

    Published in:
    Genetic Epidemiology, 2015, v. 39, n. 5, p. 376, doi. 10.1002/gepi.21902
    By:
    • Hall, Molly A.;
    • Verma, Shefali S.;
    • Wallace, John;
    • Lucas, Anastasia;
    • Berg, Richard L.;
    • Connolly, John;
    • Crawford, Dana C.;
    • Crosslin, David R.;
    • Andrade, Mariza;
    • Doheny, Kimberly F.;
    • Haines, Jonathan L.;
    • Harley, John B.;
    • Jarvik, Gail P.;
    • Kitchner, Terrie;
    • Kuivaniemi, Helena;
    • Larson, Eric B.;
    • Carrell, David S.;
    • Tromp, Gerard;
    • Vrabec, Tamara R.;
    • Pendergrass, Sarah A.
    Publication type:
    Article
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    4

    Patients with Proliferative Lupus Nephritis Have Autoantibodies That React to Moesin and Demonstrate Increased Glomerular Moesin Expression.

    Published in:
    Journal of Clinical Medicine, 2021, v. 10, n. 4, p. 793, doi. 10.3390/jcm10040793
    By:
    • Caster, Dawn J.;
    • Korte, Erik A.;
    • Merchant, Michael L.;
    • Klein, Jon B.;
    • Barati, Michelle T.;
    • Joglekar, Ami;
    • Wilkey, Daniel W.;
    • Coventry, Susan;
    • Hata, Jessica;
    • Rovin, Brad H.;
    • Harley, John B.;
    • Namjou-Khales, Bahram;
    • McLeish, Kenneth R.;
    • Powell, David W.;
    • Del Vecchio, Lucia
    Publication type:
    Article
    5
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    Identification of IFRD1 as a modifier gene for cystic fibrosis lung disease.

    Published in:
    2009
    By:
    • Gu, YuanYuan;
    • Harley, Isaac T. W.;
    • Henderson, Lindsay B.;
    • Aronow, Bruce J.;
    • Vietor, Ilja;
    • Huber, Lukas A.;
    • Harley, John B.;
    • Kilpatrick, Jeffrey R.;
    • Langefeld, Carl D.;
    • Williams, Adrienne H.;
    • Jegga, Anil G.;
    • Chen, Jing;
    • Wills-Karp, Marsha;
    • Arshad, S. Hasan;
    • Ewart, Susan L.;
    • Thio, Chloe L.;
    • Flick, Leah M.;
    • Filippi, Marie-Dominique;
    • Grimes, H. Leighton;
    • Drumm, Mitchell L.
    Publication type:
    Letter
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    Multiple Autoantibodies Display Association with Lymphopenia, Proteinuria, and Cellular Casts in a Large, Ethnically Diverse SLE Patient Cohort.

    Published in:
    Autoimmune Diseases (2090-0422), 2012, p. 1, doi. 10.1155/2012/819634
    By:
    • Lu, Rufei;
    • Robertson, Julie M.;
    • Bruner, Benjamin F.;
    • Guthridge, Joel M.;
    • Neas, Barbara R.;
    • Nath, Swapan K.;
    • Kelly, Jennifer A.;
    • Moser Sivils, Kathy L.;
    • Chakravarty, Eliza F.;
    • Kamen, Diane L.;
    • Gilkeson, Gary S.;
    • Wallace, Daniel J.;
    • Weisman, Michael H.;
    • Hal Scofield, R.;
    • Harley, John B.;
    • James, Judith A.
    Publication type:
    Article
    15

    Genome-wide linkage screen for stature and body mass index in 3.032 families: evidence for sex- and population-specific genetic effects.

    Published in:
    European Journal of Human Genetics, 2009, v. 17, n. 2, p. 258, doi. 10.1038/ejhg.2008.152
    By:
    • Sammalisto, Sampo;
    • Hiekkalinna, Tero;
    • Schwander, Karen;
    • Kardia, Sharon;
    • Weder, Alan B.;
    • Rodriguez, Beatriz L.;
    • Doria, Alessandro;
    • Kelly, Jennifer A.;
    • Bruner, Gail R.;
    • Harley, John B.;
    • Redline, Susan;
    • Larkin, Emma K.;
    • Patel, Sanjay R.;
    • Ewan, Amy J. H.;
    • Weber, James L.;
    • Perola, Markus;
    • Peltonen, Leena
    Publication type:
    Article
    16

    Specific combinations of HLA-DR2 and DR3 class II haplotypes contribute graded risk for disease susceptibility and autoantibodies in human SLE.

    Published in:
    European Journal of Human Genetics, 2007, v. 15, n. 8, p. 823, doi. 10.1038/sj.ejhg.5201827
    By:
    • Graham, Robert R.;
    • Ortmann, Ward;
    • Rodine, Peter;
    • Espe, Karl;
    • Langefeld, Carl;
    • Lange, Ethan;
    • Williams, Adrienne;
    • Beck, Stephanie;
    • Kyogoku, Chieko;
    • Moser, Kathy;
    • Gaffney, Patrick;
    • Gregersen, Peter K.;
    • Criswell, Lindsey A.;
    • Harley, John B.;
    • Behrens, Timothy W.
    Publication type:
    Article
    17
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    A nonsynonymous functional variant in integrin-α<sub>M</sub> (encoded by ITGAM) is associated with systemic lupus erythematosus.

    Published in:
    Nature Genetics, 2008, v. 40, n. 2, p. 152, doi. 10.1038/ng.71
    By:
    • Nath, Swapan K.;
    • Shizhong Han;
    • Kim-Howard, Xana;
    • Kelly, Jennifer A.;
    • Viswanathan, Parvathi;
    • Gilkeson, Gary S.;
    • Wei Chen;
    • Cheng Zhu;
    • McEver, Rodger P.;
    • Kimberly, Robert P.;
    • Alarcón-Riquelme, Marta E.;
    • Vyse, Timothy J.;
    • Quan-Zhen Li;
    • Wakeland, Edward K.;
    • Merrill, Joan T.;
    • James, Judith A.;
    • Kaufman, Kenneth M.;
    • Guthridge, Joel M.;
    • Harley, John B.
    Publication type:
    Article
    20

    Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci.

    Published in:
    Nature Genetics, 2008, v. 40, n. 2, p. 204, doi. 10.1038/ng.81
    By:
    • Harley, John B.;
    • Alarcón-Riquelme, Marta E.;
    • Criswell, Lindsey A.;
    • Jacob, Chaim O.;
    • Kimberly, Robert P.;
    • Moser, Kathy L.;
    • Tsao, Betty P.;
    • Vyse, Timothy J.;
    • Langefeld, Carl D.;
    • Nath, Swapan K.;
    • Guthridge, Joel M.;
    • Cobb, Beth L.;
    • Mirel, Daniel B.;
    • Marion, Miranda C.;
    • Williams, Adrienne H.;
    • Divers, Jasmin;
    • Wei Wang;
    • Frank, Summer G.;
    • Namjou, Bahram;
    • Gabriel, Stacey B.
    Publication type:
    Article
    21
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    A functional variant in FCRL3, encoding Fc receptor-like 3, is associated with rheumatoid arthritis and several autoimmunities.

    Published in:
    Nature Genetics, 2005, v. 37, n. 5, p. 478, doi. 10.1038/ng1540
    By:
    • Kochi, Yuta;
    • Yamada, Ryo;
    • Suzuki, Akari;
    • Harley, John B;
    • Shirasawa, Senji;
    • Sawada, Tetsuji;
    • Bae, Sang-Cheol;
    • Tokuhiro, Shinya;
    • Chang, Xiaotian;
    • Sekine, Akihiro;
    • Takahashi, Atsushi;
    • Tsunoda, Tatsuhiko;
    • Ohnishi, Yozo;
    • Kaufman, Kenneth M;
    • Kang, Changsoo Paul;
    • Kang, Changwon;
    • Otsubo, Shigeru;
    • Yumura, Wako;
    • Mimori, Akio;
    • Koike, Takao
    Publication type:
    Article
    23

    Complete tracheal Ring Deformity: A Translational Genomics approach.

    Published in:
    American Journal of Respiratory & Critical Care Medicine, 2019, v. 200, n. 10, p. E1, doi. 10.1164/rccm.201809-1626oc
    By:
    • Sinner, Debora I.;
    • Zgherea, Daniela;
    • Carey, Brenna;
    • Kaufman, K. M.;
    • Leesman, Lauren;
    • Wood, Robert E.;
    • Rutter, Michael J.;
    • de Alarcon, Alessandro;
    • Elluru, Ravindhra G.;
    • Harley, John B.;
    • Whitsett, Jeffrey A.;
    • Trapnell, Bruce C.
    Publication type:
    Article
    24
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    Identification of Four Novel Loci in Asthma in European American and African American Populations.

    Published in:
    2017
    By:
    • Almoguera, Berta;
    • Vazquez, Lyam;
    • Mentch, Frank;
    • Connolly, John;
    • Pacheco, Jennifer A.;
    • Sundaresan, Agnes S.;
    • Peissig, Peggy L.;
    • Linneman, James G.;
    • McCarty, Catherine A.;
    • Crosslin, David;
    • Carrell, David S.;
    • Lingren, Todd;
    • Namjou-Khales, Bahram;
    • Harley, John B.;
    • Larson, Eric;
    • Jarvik, Gail P.;
    • Brilliant, Murray;
    • Williams, Marc S.;
    • Kullo, Iftikhar J.;
    • Hysinger, Erik B.
    Publication type:
    journal article
    26

    Preferential Binding to Elk-1 by SLE-Associated <i>IL10</i> Risk Allele Upregulates <i>IL10</i> Expression.

    Published in:
    PLoS Genetics, 2013, v. 9, n. 10, p. 1, doi. 10.1371/journal.pgen.1003870
    By:
    • Sakurai, Daisuke;
    • Zhao, Jian;
    • Deng, Yun;
    • Kelly, Jennifer A.;
    • Brown, Elizabeth E.;
    • Harley, John B.;
    • Bae, Sang-Cheol;
    • Alarcόn-Riquelme, Marta E.;
    • Edberg, Jeffrey C.;
    • Kimberly, Robert P.;
    • Ramsey-Goldman, Rosalind;
    • Petri, Michelle A.;
    • Reveille, John D.;
    • Vilá, Luis M.;
    • Alarcón, Graciela S.;
    • Kaufman, Kenneth M.;
    • Vyse, Timothy J.;
    • Jacob, Chaim O.;
    • Gaffney, Patrick M.;
    • Sivils, Kathy Moser
    Publication type:
    Article
    27

    Trans-Ancestral Studies Fine Map the SLE-Susceptibility Locus <i>TNFSF4</i>.

    Published in:
    PLoS Genetics, 2013, v. 9, n. 7, p. 1, doi. 10.1371/journal.pgen.1003554
    By:
    • Manku, Harinder;
    • Langefeld, Carl D.;
    • Guerra, Sandra G.;
    • Malik, Talat H.;
    • Alarcon-Riquelme, Marta;
    • Anaya, Juan-Manuel;
    • Bae, Sang-Cheol;
    • Boackle, Susan A.;
    • Brown, Elizabeth E.;
    • Criswell, Lindsey A.;
    • Freedman, Barry I.;
    • Gaffney, Patrick M.;
    • Gregersen, Peter A.;
    • Guthridge, Joel M.;
    • Han, Sang-Hoon;
    • Harley, John B.;
    • Jacob, Chaim O.;
    • James, Judith A.;
    • Kamen, Diane L.;
    • Kaufman, Kenneth M.
    Publication type:
    Article
    28

    A Genome-Wide Integrative Genomic Study Localizes Genetic Factors Influencing Antibodies against Epstein-Barr Virus Nuclear Antigen 1 (EBNA-1)

    Published in:
    PLoS Genetics, 2013, v. 9, n. 1, p. 1, doi. 10.1371/journal.pgen.1003147
    By:
    • Rubicz, Rohina;
    • Yolken, Robert;
    • Drigalenko, Eugene;
    • Carless, Melanie A.;
    • Dyer, Thomas D.;
    • Bauman, Lara;
    • Melton, Phillip E.;
    • Kent Jr., Jack W.;
    • Harley, John B.;
    • Curran, Joanne E.;
    • Johnson, Matthew P.;
    • Cole, Shelley A.;
    • Almasy, Laura;
    • Moses, Eric K.;
    • Dhurandhar, Nikhil V.;
    • Kraig, Ellen;
    • Blangero, John;
    • Leach, Charles T.;
    • Göring, Harald H. H.
    Publication type:
    Article
    29

    A Comprehensive Analysis of Shared Loci between Systemic Lupus Erythematosus (SLE) and Sixteen Autoimmune Diseases Reveals Limited Genetic Overlap.

    Published in:
    PLoS Genetics, 2011, v. 7, n. 12, p. 1, doi. 10.1371/journal.pgen.1002406
    By:
    • Ramos, Paula S.;
    • Criswell, Lindsey A.;
    • Moser, Kathy L.;
    • Comeau, Mary E.;
    • Williams, Adrienne H.;
    • Pajewski, Nicholas M.;
    • Chung, Sharon A.;
    • Graham, Robert R.;
    • Zidovetzki, Raphael;
    • Kelly, Jennifer A.;
    • Kaufman, Kenneth M.;
    • Jacob, Chaim O.;
    • Vyse, Timothy J.;
    • Tsao, Betty P.;
    • Kimberly, Robert P.;
    • Gaffney, Patrick M.;
    • Alarcón-Riquelme, Marta E.;
    • Harley, John B.;
    • Langefeld, Carl D.
    Publication type:
    Article
    30

    Association of Genetic Variants in Complement Factor H and Factor H-Related Genes with Systemic Lupus Erythematosus Susceptibility.

    Published in:
    PLoS Genetics, 2011, v. 7, n. 5, p. 1, doi. 10.1371/journal.pgen.1002079
    By:
    • Zhao, Jian;
    • Wu, Hui;
    • Khosravi, Melanie;
    • Cui, Huijuan;
    • Qian, Xiaoxia;
    • Kelly, Jennifer A.;
    • Kaufman, Kenneth M.;
    • Langefeld, Carl D.;
    • Williams, Adrienne H.;
    • Comeau, Mary E.;
    • Ziegler, Julie T.;
    • Marion, Miranda C.;
    • Adler, Adam;
    • Glenn, Stuart B.;
    • Alarcón-Riquelme, Marta E.;
    • Pons-Estel, Bernardo A.;
    • Harley, John B.;
    • Bae, Sang-Cheol;
    • Bang, So-Young;
    • Cho, Soo-Kyung
    Publication type:
    Article
    31

    Differential Genetic Associations for Systemic Lupus Erythematosus Based on Anti–dsDNA Autoantibody Production.

    Published in:
    PLoS Genetics, 2011, v. 7, n. 3, p. 1, doi. 10.1371/journal.pgen.1001323
    By:
    • Chung, Sharon A.;
    • Taylor, Kimberly E.;
    • Graham, Robert R.;
    • Nititham, Joanne;
    • Lee, Annette T.;
    • Ortmann, Ward A.;
    • Jacob, Chaim O.;
    • Alarcón-Riquelme, Marta E.;
    • Tsao, Betty P.;
    • Harley, John B.;
    • Gaffney, Patrick M.;
    • Moser, Kathy L.;
    • Petri, Michelle;
    • Yesim Demirci, F.;
    • Ilyas Kamboh, M.;
    • Manzi, Susan;
    • Gregersen, Peter K.;
    • Langefeld, Carl D.;
    • Behrens, Timothy W.;
    • Criswell, Lindsey A.
    Publication type:
    Article
    32

    Risk Alleles for Systemic Lupus Erythematosus in a Large Case-Control Collection and Associations with Clinical Subphenotypes.

    Published in:
    PLoS Genetics, 2011, v. 7, n. 2, p. 1, doi. 10.1371/journal.pgen.1001311
    By:
    • Taylor, Kimberly E.;
    • Chung, Sharon A.;
    • Graham, Robert R.;
    • Ortmann, Ward A.;
    • Lee, Annette T.;
    • Langefeld, Carl D.;
    • Jacob, Chaim O.;
    • Kamboh, M. Ilyas;
    • Alarcón-Riquelme, Marta E.;
    • Tsao, Betty P.;
    • Moser, Kathy L.;
    • Gaffney, Patrick M.;
    • Harley, John B.;
    • Petri, Michelle;
    • Manzi, Susan;
    • Gregersen, Peter K.;
    • Behrens, Timothy W.;
    • Criswell, Lindsey A.
    Publication type:
    Article
    33

    High-Density SNP Screening of the Major Histocompatibility Complex in Systemic Lupus Erythematosus Demonstrates Strong Evidence for Independent Susceptibility Regions.

    Published in:
    PLoS Genetics, 2009, v. 5, n. 10, p. 1, doi. 10.1371/journal.pgen.1000696
    By:
    • Barcellos, Lisa F.;
    • May, Suzanne L.;
    • Ramsay, Patricia P.;
    • Quach, Hong L.;
    • Lane, Julie A.;
    • Nititham, Joanne;
    • Noble, Janelle A.;
    • Taylor, Kimberly E.;
    • Quach, Diana L.;
    • Chung, Sharon A.;
    • Kelly, Jennifer A.;
    • Moser, Kathy L.;
    • Behrens, Timothy W.;
    • Seldin, Michael F.;
    • Thomson, Glenys;
    • Harley, John B.;
    • Gaffney, Patrick M.;
    • Criswell, Lindsey A.
    Publication type:
    Article
    34

    Genetics of clinical expression in SLE.

    Published in:
    Autoimmunity, 2007, v. 40, n. 8, p. 602, doi. 10.1080/08916930701510962
    By:
    • Namjou, Bahram;
    • Kilpatrick, Jeff;
    • Harley, John B.
    Publication type:
    Article
    35

    Outcomes of Returning Medically Actionable Genomic Results in Pediatric Research.

    Published in:
    Journal of Personalized Medicine, 2022, v. 12, n. 11, p. 1910, doi. 10.3390/jpm12111910
    By:
    • Blumling, Amy A.;
    • Prows, Cynthia A.;
    • Harr, Margaret H.;
    • Chung, Wendy K.;
    • Clayton, Ellen Wright;
    • Holm, Ingrid A.;
    • Wiesner, Georgia L.;
    • Connolly, John J.;
    • Harley, John B.;
    • Hakonarson, Hakon;
    • McGowan, Michelle L.;
    • Miller, Erin M.;
    • Myers, Melanie F.
    Publication type:
    Article
    36
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    Trans-Ethnic Mapping of BANK1 Identifies Two Independent SLE-Risk Linkage Groups Enriched for Co-Transcriptional Splicing Marks.

    Published in:
    International Journal of Molecular Sciences, 2018, v. 19, n. 8, p. 2331, doi. 10.3390/ijms19082331
    By:
    • Martínez-Bueno, Manuel;
    • Oparina, Nina;
    • Dozmorov, Mikhail G.;
    • Marion, Miranda C.;
    • Comeau, Mary E.;
    • Gilkeson, Gary;
    • Kamen, Diane;
    • Weisman, Michael;
    • Salmon, Jane;
    • McCune, Joseph W.;
    • Harley, John B.;
    • Kimberly, Robert;
    • James, Judith A.;
    • Merrill, Joan;
    • Montgomery, Courtney;
    • Langefeld, Carl D.;
    • Alarcón-Riquelme, Marta E.
    Publication type:
    Article
    38

    Antibody Responses to Epstein‐Barr Virus in the Preclinical Period of Rheumatoid Arthritis Suggest the Presence of Increased Viral Reactivation Cycles.

    Published in:
    Arthritis & Rheumatology, 2022, v. 74, n. 4, p. 597, doi. 10.1002/art.41994
    By:
    • Fechtner, Sabrina;
    • Berens, Heather;
    • Bemis, Elizabeth;
    • Johnson, Rachel L.;
    • Guthridge, Carla J.;
    • Carlson, Nichole E.;
    • Demoruelle, M. Kristen;
    • Harley, John B.;
    • Edison, Jess D.;
    • Norris, Jill A.;
    • Robinson, William H.;
    • Deane, Kevin D.;
    • James, Judith A.;
    • Holers, V. Michael
    Publication type:
    Article
    39

    Lupus Susceptibility Region Containing CDKN1B rs34330 Mechanistically Influences Expression and Function of Multiple Target Genes, Also Linked to Proliferation and Apoptosis.

    Published in:
    Arthritis & Rheumatology, 2021, v. 73, n. 12, p. 2303, doi. 10.1002/art.41799
    By:
    • Singh, Bhupinder;
    • Maiti, Guru P.;
    • Zhou, Xujie;
    • Fazel‐Najafabadi, Mehdi;
    • Bae, Sang‐Cheol;
    • Sun, Celi;
    • Terao, Chikashi;
    • Okada, Yukinori;
    • Heng Chua, Kek;
    • Kochi, Yuta;
    • Guthridge, Joel M.;
    • Zhang, Hong;
    • Weirauch, Matthew;
    • James, Judith A.;
    • Harley, John B.;
    • Varshney, Gaurav K.;
    • Looger, Loren L.;
    • Nath, Swapan K.
    Publication type:
    Article
    40

    Pleiotropy in the Genetic Predisposition to Rheumatoid Arthritis: A Phenome‐Wide Association Study and Inverse Variance–Weighted Meta‐Analysis.

    Published in:
    Arthritis & Rheumatology, 2020, v. 72, n. 9, p. 1483, doi. 10.1002/art.41291
    By:
    • Kawai, Vivian K.;
    • Shi, Mingjian;
    • Feng, Qiping;
    • Chung, Cecilia P.;
    • Liu, Ge;
    • Cox, Nancy J.;
    • Jarvik, Gail P.;
    • Lee, Ming T. M.;
    • Hebbring, Scott J.;
    • Harley, John B.;
    • Kaufman, Kenneth M.;
    • Namjou, Bahram;
    • Larson, Eric;
    • Gordon, Adam S.;
    • Roden, Dan M.;
    • Stein, C. Michael;
    • Mosley, Jonathan D.
    Publication type:
    Article
    41

    Discerning Risk of Disease Transition in Relatives of Systemic Lupus Erythematosus Patients Utilizing Soluble Mediators and Clinical Features.

    Published in:
    Arthritis & Rheumatology, 2017, v. 69, n. 3, p. 630, doi. 10.1002/art.40004
    By:
    • Munroe, Melissa E.;
    • Young, Kendra A.;
    • Kamen, Diane L.;
    • Guthridge, Joel M.;
    • Niewold, Timothy B.;
    • Costenbader, Karen H.;
    • Weisman, Michael H.;
    • Ishimori, Mariko L.;
    • Wallace, Daniel J.;
    • Gilkeson, Gary S.;
    • Karp, David R.;
    • Harley, John B.;
    • Norris, Jill M.;
    • James, Judith A.
    Publication type:
    Article
    42
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    End-Stage Renal Disease in African Americans With Lupus Nephritis Is Associated With APOL1.

    Published in:
    Arthritis & Rheumatology, 2014, v. 66, n. 2, p. 390, doi. 10.1002/art.38220
    By:
    • Freedman, Barry I.;
    • Langefeld, Carl D.;
    • Andringa, Kelly K.;
    • Croker, Jennifer A.;
    • Williams, Adrienne H.;
    • Garner, Neva E.;
    • Birmingham, Daniel J.;
    • Hebert, Lee A.;
    • Hicks, Pamela J.;
    • Segal, Mark S.;
    • Edberg, Jeffrey C.;
    • Brown, Elizabeth E.;
    • Alarcón, Graciela S.;
    • Costenbader, Karen H.;
    • Comeau, Mary E.;
    • Criswell, Lindsey A.;
    • Harley, John B.;
    • James, Judith A.;
    • Kamen, Diane L.;
    • Lim, S. Sam
    Publication type:
    Article
    50

    Genetic variation in the CRP promoter: association with systemic lupus erythematosus.

    Published in:
    Human Molecular Genetics, 2008, v. 17, n. 8, p. 1147, doi. 10.1093/hmg/ddn004
    By:
    • Edberg, Jeffrey C.;
    • Wu, Jianming;
    • Langefeld, Carl D.;
    • Brown, Elizabeth E.;
    • Marion, Miranda C.;
    • McGwin, Gerald;
    • Petri, Michelle;
    • Ramsey-Goldman, Rosalind;
    • Reveille, John D.;
    • Frank, Summer G.;
    • Kaufman, Kenneth M.;
    • Harley, John B.;
    • Alarcón, Graciela S.;
    • Kimberly, Robert P.
    Publication type:
    Article