Works by Harki, Daniel A.

Results: 18

Differential Inhibition of APOBEC3 DNA‐Mutator Isozymes by Fluoro‐ and Non‐Fluoro‐Substituted 2′‐Deoxyzebularine Embedded in Single‐Stranded DNA.

Published in:

ChemBioChem, 2020, v. 21, n. 7, p. 1028, doi. 10.1002/cbic.201900505

By:

Kvach, Maksim V.;
Barzak, Fareeda M.;
Harjes, Stefan;
Schares, Henry A. M.;
Kurup, Harikrishnan M.;
Jones, Katherine F.;
Sutton, Lorraine;
Donahue, John;
D'Aquila, Richard T.;
Jameson, Geoffrey B.;
Harki, Daniel A.;
Krause, Kurt L.;
Harjes, Elena;
Filichev, Vyacheslav V.

Publication type:

Article

SARS-CoV-2 nsp14 Exoribonuclease Removes the Natural Antiviral 3′-Deoxy-3′,4′-didehydro-cytidine Nucleotide from RNA.

Published in:

Viruses (1999-4915), 2022, v. 14, n. 8, p. 1790, doi. 10.3390/v14081790

By:

Moeller, Nicholas H.;
Passow, Kellan T.;
Harki, Daniel A.;
Aihara, Hideki

Publication type:

Article

Expanding Catch and Release DNA Decoy (CRDD) Technology with Pyrimidine Mimics.

Published in:

Chemistry - A European Journal, 2022, v. 28, n. 58, p. 1, doi. 10.1002/chem.202201355

By:

Kennelly, Samantha A.;
Moorthy, Ramkumar;
Otero, Ruben Silva;
Harki, Daniel A.

Publication type:

Article

Function‐Oriented and Modular (+/−)‐cis‐Pseudoguaianolide Synthesis: Discovery of New Nrf2 Activators and NF‐κB Inhibitors.

Published in:

Chemistry - A European Journal, 2021, v. 27, n. 17, p. 5564, doi. 10.1002/chem.202100038

By:

Emmetiere, Fabien;
Ratnayake, Ranjala;
Schares, Henry A. M.;
Jones, Katherine F. M.;
Bevan–Smith, Emily;
Luesch, Hendrik;
Harki, Daniel A.;
Grenning, Alexander J.

Publication type:

Article

Selective N‐Terminal BET Bromodomain Inhibitors by Targeting Non‐Conserved Residues and Structured Water Displacement**.

Published in:

Angewandte Chemie, 2021, v. 133, n. 3, p. 1240, doi. 10.1002/ange.202008625

By:

Cui, Huarui;
Divakaran, Anand;
Pandey, Anil K.;
Johnson, Jorden A.;
Zahid, Huda;
Hoell, Zachariah J.;
Ellingson, Mikael O.;
Shi, Ke;
Aihara, Hideki;
Harki, Daniel A.;
Pomerantz, William C. K.

Publication type:

Article

Development of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding.

Published in:

Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-38732-x

By:

Faber, Erik B.;
Sun, Luxin;
Tang, Jian;
Roberts, Emily;
Ganeshkumar, Sornakala;
Wang, Nan;
Rasmussen, Damien;
Majumdar, Abir;
Hirsch, Laura E.;
John, Kristen;
Yang, An;
Khalid, Hira;
Hawkinson, Jon E.;
Levinson, Nicholas M.;
Chennathukuzhi, Vargheese;
Harki, Daniel A.;
Schönbrunn, Ernst;
Georg, Gunda I.

Publication type:

Article

Selective N‐Terminal BET Bromodomain Inhibitors by Targeting Non‐Conserved Residues and Structured Water Displacement**.

Published in:

Angewandte Chemie International Edition, 2021, v. 60, n. 3, p. 1220, doi. 10.1002/anie.202008625

By:

Cui, Huarui;
Divakaran, Anand;
Pandey, Anil K.;
Johnson, Jorden A.;
Zahid, Huda;
Hoell, Zachariah J.;
Ellingson, Mikael O.;
Shi, Ke;
Aihara, Hideki;
Harki, Daniel A.;
Pomerantz, William C. K.

Publication type:

Article

Inhibition of Guanosine Monophosphate Synthetase by the Substrate Enantiomer L-XMP.

Published in:

ChemBioChem, 2012, v. 13, n. 17, p. 2517, doi. 10.1002/cbic.201200503

By:

Struntz, Nicholas B.;
Hu, Tianshun;
White, Brian R.;
Olson, Margaret E.;
Harki, Daniel A.

Publication type:

Article

Synthesis of a Universal 5-Nitroindole Ribonucleotide and Incorporation into RNA by a Viral RNA-Dependent RNA Polymerase.

Published in:

ChemBioChem, 2007, v. 8, n. 12, p. 1359, doi. 10.1002/cbic.200700160

By:

Harki, Daniel A.;
Graci, Jason D.;
Edathil, Jocelyn P.;
Castro, Christian;
Cameron, Craig E.;
Peterson, Blake R.

Publication type:

Article

Detyrosinated microtubules modulate mechanotransduction in heart and skeletal muscle.

Published in:

Nature Communications, 2015, v. 6, n. 10, p. 8526, doi. 10.1038/ncomms9526

By:

Kerr, Jaclyn P.;
Robison, Patrick;
Shi, Guoli;
Bogush, Alexey I.;
Kempema, Aaron M.;
Hexum, Joseph K.;
Becerra, Natalia;
Harki, Daniel A.;
Martin, Stuart S.;
Raiteri, Roberto;
Prosser, Benjamin L.;
Ward, Christopher W.

Publication type:

Article

Front Cover: Helenalin Analogues Targeting NF‐κB p65: Thiol Reactivity and Cellular Potency Studies of Varied Electrophiles (ChemMedChem 4/2018).

Published in:

ChemMedChem, 2018, v. 13, n. 4, p. 288, doi. 10.1002/cmdc.201800079

By:

Widen, John C.;
Kempema, Aaron M.;
Baur, Jordan W.;
Skopec, Hannah M.;
Edwards, Jacob T.;
Brown, Tenley J.;
Brown, Dennis A.;
Meece, Frederick A.;
Harki, Daniel A.

Publication type:

Article

Helenalin Analogues Targeting NF‐κB p65: Thiol Reactivity and Cellular Potency Studies of Varied Electrophiles.

Published in:

ChemMedChem, 2018, v. 13, n. 4, p. 303, doi. 10.1002/cmdc.201700752

By:

Widen, John C.;
Kempema, Aaron M.;
Baur, Jordan W.;
Skopec, Hannah M.;
Edwards, Jacob T.;
Brown, Tenley J.;
Brown, Dennis A.;
Meece, Frederick A.;
Harki, Daniel A.

Publication type:

Article

Back Cover: Small-Molecule APOBEC3G DNA Cytosine Deaminase Inhibitors Based on a 4-Amino-1,2,4-triazole-3-thiol Scaffold (ChemMedChem 1/2013).

Published in:

ChemMedChem, 2013, v. 8, n. 1, p. 172, doi. 10.1002/cmdc.201290068

By:

Olson, Margaret E.;
Li, Ming;
Harris, Reuben S.;
Harki, Daniel A.

Publication type:

Article

Small-Molecule APOBEC3G DNA Cytosine Deaminase Inhibitors Based on a 4-Amino-1,2,4-triazole-3-thiol Scaffold.

Published in:

ChemMedChem, 2013, v. 8, n. 1, p. 112, doi. 10.1002/cmdc.201200411

By:

Olson, Margaret E.;
Li, Ming;
Harris, Reuben S.;
Harki, Daniel A.

Publication type:

Article

A compact stem-loop DNA aptamer targets a uracil-binding pocket in the SARS-CoV-2 nucleocapsid RNA-binding domain.

Published in:

Nucleic Acids Research, 2024, v. 52, n. 21, p. 13138, doi. 10.1093/nar/gkae874

By:

Esler, Morgan A;
Belica, Christopher A;
Rollie, Joseph A;
Brown, William L;
Moghadasi, Seyed Arad;
Shi, Ke;
Harki, Daniel A;
Harris, Reuben S;
Aihara, Hideki

Publication type:

Article

Immunodetection of human topoisomerase I-DNA covalent complexes.

Published in:

Nucleic Acids Research, 2016, v. 44, n. 6, p. 2816, doi. 10.1093/nar/gkw109

By:

Patel, Anand G.;
Flatten, Karen S.;
Peterson, Kevin L.;
Beito, Thomas G.;
Schneider, Paula A.;
Perkins, Angela L.;
Harki, Daniel A.;
Kaufmann, Scott H.

Publication type:

Article

Recent progress and structural analyses of domain‐selective BET inhibitors.

Published in:

Medicinal Research Reviews, 2023, v. 43, n. 4, p. 972, doi. 10.1002/med.21942

By:

Divakaran, Anand;
Harki, Daniel A.;
Pomerantz, William C. K.

Publication type:

Article

Active site plasticity and possible modes of chemical inhibition of the human DNA deaminase APOBEC3B.

Published in:

FASEB Bioadvances, 2020, v. 2, n. 1, p. 49, doi. 10.1096/fba.2019-00068

By:

Shi, Ke;
Demir, Özlem;
Carpenter, Michael A.;
Banerjee, Surajit;
Harki, Daniel A.;
Amaro, Rommie E.;
Harris, Reuben S.;
Aihara, Hideki

Publication type:

Article