Works by Hargrove, Tatiana Y.

Results: 9

Unique Structural Features Relate to Evolutionary Adaptation of Cytochrome P450 in the Abyssal Zone.

Published in:

International Journal of Molecular Sciences, 2025, v. 26, n. 12, p. 5689, doi. 10.3390/ijms26125689

By:

Hargrove, Tatiana Y.;
Lamb, David C.;
Wawrzak, Zdzislaw;
Minasov, George;
Goldstone, Jared V.;
Kelly, Steven L.;
Stegeman, John J.;
Lepesheva, Galina I.

Publication type:

Article

Oxygen‐18 Labeling Reveals a Mixed Fe−O Mechanism in the Last Step of Cytochrome P450 51 Sterol 14α‐Demethylation.

Published in:

Angewandte Chemie, 2024, v. 136, n. 9, p. 1, doi. 10.1002/ange.202317711

By:

McCarty, Kevin D.;
Tateishi, Yasuhiro;
Hargrove, Tatiana Y.;
Lepesheva, Galina I.;
Guengerich, F. Peter

Publication type:

Article

Sequence variation in CYP51A from the Y strain of Trypanosoma cruzi alters its sensitivity to inhibition.

Published in:

FEBS Letters, 2014, v. 588, n. 21, p. 3878, doi. 10.1016/j.febslet.2014.08.030

By:

Cherkesova, Tatiana S.;
Hargrove, Tatiana Y.;
Vanrell, M. Cristina;
Ges, Igor;
Usanov, Sergey A.;
Romano, Patricia S.;
Lepesheva, Galina I.

Publication type:

Article

Unravelling the role of transient redox partner complexes in P450 electron transfer mechanics.

Published in:

Scientific Reports, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41598-022-20671-0

By:

Hargrove, Tatiana Y.;
Lamb, David C.;
Smith, Jarrod A.;
Wawrzak, Zdzislaw;
Kelly, Steven L.;
Lepesheva, Galina I.

Publication type:

Article

Oxygen‐18 Labeling Reveals a Mixed Fe−O Mechanism in the Last Step of Cytochrome P450 51 Sterol 14α‐Demethylation.

Published in:

Angewandte Chemie International Edition, 2024, v. 63, n. 9, p. 1, doi. 10.1002/anie.202317711

By:

McCarty, Kevin D.;
Tateishi, Yasuhiro;
Hargrove, Tatiana Y.;
Lepesheva, Galina I.;
Guengerich, F. Peter

Publication type:

Article

Oxygen‐18 Labeling Reveals a Mixed Fe−O Mechanism in the Last Step of Cytochrome P450 51 Sterol 14α‐Demethylation.

Published in:

Angewandte Chemie International Edition, 2024, v. 63, n. 9, p. 1, doi. 10.1002/anie.202317711

By:

McCarty, Kevin D.;
Tateishi, Yasuhiro;
Hargrove, Tatiana Y.;
Lepesheva, Galina I.;
Guengerich, F. Peter

Publication type:

Article

Concerning P450 Evolution: Structural Analyses Support Bacterial Origin of Sterol 14α-Demethylases.

Published in:

Molecular Biology & Evolution, 2021, v. 38, n. 3, p. 952, doi. 10.1093/molbev/msaa260

By:

Lamb, David C;
Hargrove, Tatiana Y;
Zhao, Bin;
Wawrzak, Zdzislaw;
Goldstone, Jared V;
Nes, William David;
Kelly, Steven L;
Waterman, Michael R;
Stegeman, John J;
Lepesheva, Galina I

Publication type:

Article

VFV as a New Effective CYP51 Structure-Derived Drug Candidate for Chagas Disease and Visceral Leishmaniasis.

Published in:

2015

By:

Lepesheva, Galina I.;
Hargrove, Tatiana Y.;
Rachakonda, Girish;
Wawrzak, Zdzislaw;
Pomel, Sébastien;
Cojean, Sandrine;
Nde, Pius N.;
Nes, W. David;
Locuson, Charles W.;
Calcutt, M. Wade;
Waterman, Michael R.;
Daniels, J. Scott;
Loiseau, Philippe M.;
Villalta, Fernando

Publication type:

journal article

VNI Cures Acute and Chronic Experimental Chagas Disease.

Published in:

Journal of Infectious Diseases, 2013, v. 208, n. 3, p. 504, doi. 10.1093/infdis/jit042

By:

Villalta, Fernando;
Dobish, Mark C.;
Nde, Pius N.;
Kleshchenko, Yulia Y.;
Hargrove, Tatiana Y.;
Johnson, Candice A.;
Waterman, Michael R.;
Johnston, Jeffrey N.;
Lepesheva, Galina I.

Publication type:

Article