Works by Hargreaves, Richard
Results: 61
Addition of an NK<sub>1</sub> receptor antagonist to an SSRI did not enhance the antidepressant effects of SSRI monotherapy: results from a randomized clinical trial in patients with major depressive disorder.
- Published in:
- Human Psychopharmacology: Clinical & Experimental, 2014, v. 29, n. 6, p. 568, doi. 10.1002/hup.2444
- By:
- Publication type:
- Article
In vitro characterization of a γ-secretase radiotracer in mammalian brain.
- Published in:
- Journal of Neurochemistry, 2006, v. 96, n. 1, p. 171, doi. 10.1111/j.1471-4159.2005.03525.x
- By:
- Publication type:
- Article
Regional Cerebral Glucose Metabolism and Blood Flow During the Silent Phase of Methylmercury Neurotoxicity in Rats.
- Published in:
- Journal of Neurochemistry, 1988, v. 51, n. 5, p. 1350, doi. 10.1111/j.1471-4159.1988.tb01096.x
- By:
- Publication type:
- Article
The role of neuroimaging in headache.
- Published in:
- 2002
- By:
- Publication type:
- journal article
Modeling Effect of a γ-Secretase Inhibitor on Amyloid- β Dynamics Reveals Significant Role of an Amyloid Clearance Mechanism.
- Published in:
- Bulletin of Mathematical Biology, 2011, v. 73, n. 1, p. 230, doi. 10.1007/s11538-010-9540-5
- By:
- Publication type:
- Article
Ex Vivo Imaging of Pancreatic Beta Cells using a Radiolabeled GLP-1 Receptor Agonist.
- Published in:
- Molecular Imaging & Biology, 2012, v. 14, n. 1, p. 79, doi. 10.1007/s11307-011-0481-7
- By:
- Publication type:
- Article
Dual in vivo quantification of integrin-targeted and protease-activated agents in cancer using fluorescence molecular tomography (FMT).
- Published in:
- 2010
- By:
- Publication type:
- journal article
PET imaging studies in rhesus monkey with the cannabinoid-1 (CB1) receptor ligand [11C]CB-119.
- Published in:
- 2009
- By:
- Publication type:
- journal article
PET Imaging Studies in Rhesus Monkey with the Cannabinoid-1 (CB1) Receptor Ligand [<sup>11</sup>C]CB-119.
- Published in:
- Molecular Imaging & Biology, 2009, v. 11, n. 4, p. 246, doi. 10.1007/s11307-008-0194-8
- By:
- Publication type:
- Article
Visualization and quantification of neurokinin-1 (NK1) receptors in the human brain.
- Published in:
- 2005
- By:
- Publication type:
- journal article
Synthesis and characterization of a potent, selective, radiolabeled substance-P antagonist for NK<sub>1</sub> receptor quantitation: ([<sup>18</sup>F]SPA-RQ)
- Published in:
- 2004
- By:
- Publication type:
- journal article
Effect of a novel histamine subtype-3 receptor inverse agonist and modafinil on EEG power spectra during sleep deprivation and recovery sleep in male volunteers.
- Published in:
- Psychopharmacology, 2011, v. 215, n. 4, p. 643, doi. 10.1007/s00213-010-2158-3
- By:
- Publication type:
- Article
In VivoOptical Imaging of LacZ Expression Using lacZTransgenic Mice.
- Published in:
- Assay & Drug Development Technologies, 2009, v. 7, n. 4, p. 391, doi. 10.1089/adt.2009.0195
- By:
- Publication type:
- Article
From LBR-101 to Fremanezumab for Migraine.
- Published in:
- 2018
- By:
- Publication type:
- journal article
Inhibition of O-GlcNAcase leads to elevation of O-GlcNAc tau and reduction of tauopathy and cerebrospinal fluid tau in rTg4510 mice.
- Published in:
- Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0181-0
- By:
- Publication type:
- Article
<sup>11</sup>C-MK-8278 PET as a Tool for Pharmacodynamic Brain Occupancy of Histamine 3 Receptor Inverse Agonists.
- Published in:
- Journal of Nuclear Medicine, 2014, v. 55, n. 1, p. 65, doi. 10.2967/jnumed.113.122515
- By:
- Publication type:
- Article
Clinical Evaluation of Brain CB-1 Receptor Occupancy of a Novel CB-1R Inverse Agonist Using CB-1R PET.
- Published in:
- Diabetes, 2007, v. 56, p. A693
- By:
- Publication type:
- Article
CNS response to a thermal stressor in human volunteers and rats may predict the clinical utility of analgesics.
- Published in:
- Drug Development Research, 2007, v. 68, n. 1, p. 23, doi. 10.1002/ddr.20163
- By:
- Publication type:
- Article
Characteristic time courses of cortical and medullary sodium signals measured by noninvasive <sup>23</sup>Na-MRI in rat kidney induced by furosemide.
- Published in:
- Journal of Magnetic Resonance Imaging, 2015, v. 41, n. 6, p. 1622, doi. 10.1002/jmri.24732
- By:
- Publication type:
- Article
Erratum to: Why does Sleep Stop Migraine?
- Published in:
- 2014
- By:
- Publication type:
- Correction Notice
Why Does Sleep Stop Migraine?
- Published in:
- Current Pain & Headache Reports, 2013, v. 17, n. 10, p. 1, doi. 10.1007/s11916-013-0369-0
- By:
- Publication type:
- Article
Advances in the pharmacologic treatment of tension-type headache.
- Published in:
- Current Pain & Headache Reports, 2008, v. 12, n. 6, p. 442, doi. 10.1007/s11916-008-0075-5
- By:
- Publication type:
- Article
Thalamic sensitization transforms localized pain into widespread allodynia.
- Published in:
- Annals of Neurology, 2010, v. 68, n. 1, p. 81, doi. 10.1002/ana.21994
- By:
- Publication type:
- Article
Preliminary evaluation of the amyloid PET Radioligand [18F]MK-3328 in Alzheimer's Disease patients
- Published in:
- 2011
- By:
- Publication type:
- Abstract
Development of the amyloid PET radioligand [<sup>18</sup>F]MK-3328
- Published in:
- 2010
- By:
- Publication type:
- Abstract
In vitro Characterization of MK-3328: A Novel Fluorinated Positron Emission Tomography Tracer for Plaques
- Published in:
- 2010
- By:
- Publication type:
- Abstract
P1-222: In vivo proton MRS biomarkers of geriatric Rhesus monkey brain show the gliosis and neuronal degeneration characteristic of human Alzheimer's disease
- Published in:
- 2008
- By:
- Publication type:
- Abstract
AUTHORS WANTED.
- Published in:
- Notes & Queries, 1915, v. 12, n. 290, p. 48-e
- By:
- Publication type:
- Article
Lost but making progress--Where will new analgesic drugs come from?
- Published in:
- Science Translational Medicine, 2014, v. 6, n. 249, p. 1, doi. 10.1126/scitranslmed.3008320
- By:
- Publication type:
- Article
Calcitonin Gene‐Related Peptide Modulators – The History and Renaissance of a New Migraine Drug Class.
- Published in:
- Headache: The Journal of Head & Face Pain, 2019, v. 59, n. 6, p. 951, doi. 10.1111/head.13510
- By:
- Publication type:
- Article
Brain Imaging in Migraine Research.
- Published in:
- Headache: The Journal of Head & Face Pain, 2010, v. 50, n. 9, p. 1523, doi. 10.1111/j.1526-4610.2010.01761.x
- By:
- Publication type:
- Article
Automated one-step radiosynthesis of the CB<sub>1</sub> receptor imaging agent [<sup>18</sup>F]MK-9470.
- Published in:
- 2014
- By:
- Publication type:
- Other
Quantitative Electroencephalography Within Sleep/Wake States Differentiates GABA<sub>A</sub> Modulators Eszopiclone and Zolpidem From Dual Orexin Receptor Antagonists in Rats.
- Published in:
- Neuropsychopharmacology, 2013, v. 38, n. 12, p. 2401, doi. 10.1038/npp.2013.139
- By:
- Publication type:
- Article
Imaging Drugs with and without Clinical Analgesic Efficacy.
- Published in:
- Neuropsychopharmacology, 2011, v. 36, n. 13, p. 2659, doi. 10.1038/npp.2011.156
- By:
- Publication type:
- Article
Lack of efficacy of L-759274, a novel neurokinin 1 (substance P) receptor antagonist, for the treatment of generalized anxiety disorder.
- Published in:
- International Journal of Neuropsychopharmacology, 2013, v. 16, n. 1, p. 1, doi. 10.1017/S1461145712000065
- By:
- Publication type:
- Article
Gender and age affect NK1 receptors in the human brain – a positron emission tomography study with [18F]SPA-RQ.
- Published in:
- International Journal of Neuropsychopharmacology, 2007, v. 10, n. 2, p. 219, doi. 10.1017/S1461145706006572
- By:
- Publication type:
- Article
Biomarkers in Drug Development: A Handbook of Practice, Application, and Strategy. Edited by Michael R Bleavins, Claudio Carini, Mallé Jurima-Romet and Ramin Rahbari.
- Published in:
- ChemMedChem, 2011, v. 6, n. 5, p. 937, doi. 10.1002/cmdc.201000433
- By:
- Publication type:
- Article
The synthesis and preclinical evaluation in rhesus monkey of [.
- Published in:
- Synapse, 2011, v. 65, n. 4, p. 261, doi. 10.1002/syn.20842
- By:
- Publication type:
- Article
Synthesis, characterization, and monkey PET studies of [<sup>18</sup>F]MK-1312, a PET tracer for quantification of mGluR1 receptor occupancy by MK-5435.
- Published in:
- Synapse, 2011, v. 65, n. 2, p. 125, doi. 10.1002/syn.20826
- By:
- Publication type:
- Article
Inverse agonist histamine H3 receptor PET tracers labelled with carbon-11 or fluorine-18.
- Published in:
- Synapse, 2009, v. 63, n. 12, p. 1122, doi. 10.1002/syn.20689
- By:
- Publication type:
- Article
PET imaging of neurokinin-1 receptors with [<sup>18</sup>F]SPA-RQ in human subjects: Assessment of reference tissue models and their test-retest reproducibility.
- Published in:
- Synapse, 2007, v. 61, n. 4, p. 242, doi. 10.1002/syn.20361
- By:
- Publication type:
- Article
Synthesis, characterization, and first successful monkey imaging studies of metabotropic glutamate receptor subtype 5 (mGluR5) PET radiotracers.
- Published in:
- Synapse, 2005, v. 56, n. 4, p. 205, doi. 10.1002/syn.20147
- By:
- Publication type:
- Article
A role for fMRI in optimizing CNS drug development.
- Published in:
- Nature Reviews Drug Discovery, 2006, v. 5, n. 5, p. 411, doi. 10.1038/nrd2027
- By:
- Publication type:
- Article
Clinical Biomarkers in Drug Discovery and Development.
- Published in:
- Nature Reviews Drug Discovery, 2003, v. 2, n. 7, p. 566, doi. 10.1038/nrd1130
- By:
- Publication type:
- Article
Competitive Binding of Ozanimod and Other Sphingosine 1-Phosphate Receptor Modulators at Receptor Subtypes 1 and 5.
- Published in:
- Frontiers in Pharmacology, 2022, v. 13, p. 1, doi. 10.3389/fphar.2022.892097
- By:
- Publication type:
- Article
Development of aprepitant, the first neurokinin-1 receptor antagonist for the prevention of chemotherapy-induced nausea and vomiting.
- Published in:
- Annals of the New York Academy of Sciences, 2011, v. 1222, n. 1, p. 40, doi. 10.1111/j.1749-6632.2011.05961.x
- By:
- Publication type:
- Article
Widespread cell stress and mitochondrial dysfunction occur in patients with early Alzheimer's disease.
- Published in:
- Science Translational Medicine, 2022, v. 14, n. 658, p. 1, doi. 10.1126/scitranslmed.abk1051
- By:
- Publication type:
- Article
Ten Years of Rizatriptan: From Development to Clinical Science and Future Directions.
- Published in:
- Headache: The Journal of Head & Face Pain, 2009, v. 49, p. S3, doi. 10.1111/j.1526-4610.2008.01335.x
- By:
- Publication type:
- Article
Refractory Migraine and Chronic Migraine: Pathophysiological Mechanisms.
- Published in:
- 2008
- By:
- Publication type:
- Correction Notice
Refractory Migraine and Chronic Migraine: Pathophysiological Mechanisms.
- Published in:
- Headache: The Journal of Head & Face Pain, 2008, v. 48, n. 6, p. 799, doi. 10.1111/j.1526-4610.2008.01157.x
- By:
- Publication type:
- Article