Works by Hardiman, Orla

Results: 198

Acceptance and Decision Making in Amyotrophic Lateral Sclerosis From a Life-Course Perspective.

Published in:

2014

By:

Foley, Geraldine;
Timonen, Virpi;
Hardiman, Orla

Publication type:

Journal Article

Clinical validation of a novel hand dexterity measurement device.

Published in:

PLoS Digital Health, 2025, v. 4, n. 3, p. 1, doi. 10.1371/journal.pdig.0000744

By:

Hayden, Conor D.;
Murphy, Bruce P.;
Gilsenan, Deirdre;
Nasseroleslami, Bahman;
Hardiman, Orla;
Murray, Deirdre

Publication type:

Article

Toward a Digital Health Intervention for Vestibular Rehabilitation: Usability and Subjective Outcomes of a Novel Platform.

Published in:

Frontiers in Neurology, 2022, v. 13, p. 1, doi. 10.3389/fneur.2022.836796

By:

Meldrum, Dara;
Murray, Deirdre;
Vance, Roisin;
Coleman, Sarah;
McConnell, Sonya;
Hardiman, Orla;
McConn Walsh, Rory

Publication type:

Article

Extra-motor manifestations in post-polio syndrome (PPS): fatigue, cognitive symptoms and radiological features.

Published in:

Neurological Sciences, 2021, v. 42, n. 11, p. 4569, doi. 10.1007/s10072-021-05130-4

By:

Li Hi Shing, Stacey;
Lope, Jasmin;
Chipika, Rangariroyashe H.;
Hardiman, Orla;
Bede, Peter

Publication type:

Article

Reldesemtiv in Amyotrophic Lateral Sclerosis: Results From the COURAGE-ALS Randomized Clinical Trial.

Published in:

JAMA Neurology, 2025, v. 82, n. 5, p. 477, doi. 10.1001/jamaneurol.2025.0241

By:

Shefner, Jeremy M.;
Cudkowicz, Merit E.;
Genge, Angela;
Hardiman, Orla;
Al-Chalabi, Ammar;
Andrews, Jinsy A.;
Chio, Adriano;
Corcia, Philippe;
Couratier, Philippe;
de Carvalho, Mamede;
Heiman-Patterson, Terry;
Henderson, Robert D.;
Ingre, Caroline;
Johnston, Wendy;
Ludolph, Albert;
Maragakis, Nicholas J.;
Miller, Timothy M.;
Mora, Jesus S.;
Petri, Susanne;
Simmons, Zachary

Publication type:

Article

Incidence of Syndromes Associated With Frontotemporal Lobar Degeneration in 9 European Countries.

Published in:

JAMA Neurology, 2023, v. 80, n. 3, p. 279, doi. 10.1001/jamaneurol.2022.5128

By:

Logroscino, Giancarlo;
Piccininni, Marco;
Graff, Caroline;
Hardiman, Orla;
Ludolph, Albert C.;
Moreno, Fermin;
Otto, Markus;
Remes, Anne M.;
Rowe, James B.;
Seelaar, Harro;
Solje, Eino;
Stefanova, Elka;
Traykov, Latchezar;
Jelic, Vesna;
Rydell, Melissa Taheri;
Pender, Niall;
Anderl-Straub, Sarah;
Barandiaran, Myriam;
Gabilondo, Alazne;
Krüger, Johanna

Publication type:

Article

Lifetime Risk and Heritability of Amyotrophic Lateral Sclerosis.

Published in:

JAMA Neurology, 2019, v. 76, n. 11, p. 1367, doi. 10.1001/jamaneurol.2019.2044

By:

Ryan, Marie;
Heverin, Mark;
McLaughlin, Russell L.;
Hardiman, Orla

Publication type:

Article

Clustering of Neuropsychiatric Disease in First-Degree and Second-Degree Relatives of Patients With Amyotrophic Lateral Sclerosis.

Published in:

JAMA Neurology, 2017, v. 74, n. 12, p. 1425, doi. 10.1001/jamaneurol.2017.2699

By:

O'Brien, Margaret;
Burke, Tom;
Heverin, Mark;
Vajda, Alice;
McLaughlin, Russell;
Gibbons, John;
Byrne, Susan;
Pinto-Grau, Marta;
Elamin, Marwa;
Pender, Niall;
Hardiman, Orla

Publication type:

Article

Heritability of Amyotrophic Lateral Sclerosis.

Published in:

JAMA Neurology, 2015, v. 72, n. 8, p. 857, doi. 10.1001/jamaneurol.2014.4049

By:

McLaughlin, Russell Lewis;
Vajda, Alice;
Hardiman, Orla

Publication type:

Article

Polyethyleneimine facilitates the growth and electrophysiological characterization of iPSC-derived motor neurons.

Published in:

Scientific Reports, 2024, v. 14, n. 1, p. 1, doi. 10.1038/s41598-024-77710-1

By:

Yang, Meimei;
You, Daofeng;
Liu, Gang;
Lu, Yin;
Yang, Guangming;
O'Brien, Timothy;
Henshall, David C.;
Hardiman, Orla;
Cai, Li;
Liu, Min;
Shen, Sanbing

Publication type:

Article

Screening for replication of genome-wide SNP associations in sporadic ALS.

Published in:

European Journal of Human Genetics, 2009, v. 17, n. 2, p. 213, doi. 10.1038/ejhg.2008.194

By:

Cronin, Simon;
Tomik, Barbara;
Bradley, Daniel G.;
Slowik, Agnieszka;
Hardiman, Orla

Publication type:

Article

The Study of Language in the Amyotrophic Lateral Sclerosis - Frontotemporal Spectrum Disorder: a Systematic Review of Findings and New Perspectives.

Published in:

Neuropsychology Review, 2018, v. 28, n. 2, p. 251, doi. 10.1007/s11065-018-9375-7

By:

Pinto-Grau, Marta;
Hardiman, Orla;
Pender, Niall

Publication type:

Article

Boosting controlled autoimmunity: a new therapeutic target for CNS disorders.

Published in:

Expert Review of Neurotherapeutics, 2008, v. 8, n. 5, p. 819, doi. 10.1586/14737175.8.5.819

By:

del Barco, Diana García1;
Berlanga, Jorge;
Penton, Eduardo;
Hardiman, Orla;
Montero, Enrique

Publication type:

Article

ANG mutations segregate with familial and 'sporadic' amyotrophic lateral sclerosis.

Published in:

Nature Genetics, 2006, v. 38, n. 4, p. 411, doi. 10.1038/ng1742

By:

Greenway, Matthew J.;
Andersen, Peter M.;
Russ, Carsten;
Ennis, Sean;
Cashman, Susan;
Donaghy, Colette;
Patterson, Victor;
Swingler, Robert;
Kieran, Dairin;
Prehn, Jochen;
Morrison, Karen E.;
Green, Andrew;
Acharya, K. Ravi;
Brown Jr., Robert H.;
Hardiman, Orla

Publication type:

Article

Assessing individual quality of life in amyotrophic lateral sclerosis.

Published in:

2001

By:

Clarke, Sarah;
Hickey, Anne;
O'Boyle, Ciaran;
Hardiman, Orla;
Clarke, S;
Hickey, A;
O'Boyle, C;
Hardiman, O

Publication type:

journal article

A Clinical Decision Support System for the Prediction of Quality of Life in ALS.

Published in:

Journal of Personalized Medicine, 2022, v. 12, n. 3, p. 435, doi. 10.3390/jpm12030435

By:

Antoniadi, Anna Markella;
Galvin, Miriam;
Heverin, Mark;
Wei, Lan;
Hardiman, Orla;
Mooney, Catherine

Publication type:

Article

Mismatch negativity as an indicator of cognitive sub-Domain Dysfunction in amyotrophic lateral sclerosis.

Published in:

Frontiers in Neurology, 2017, p. 1, doi. 10.3389/fneur.2017.00395

By:

Iyer, Parameswaran Mahadeva;
Mohr, Kieran;
Broderick, Michael;
Gavin, Brighid;
Burke, Tom;
Bede, Peter;
Pinto-Grau, Marta;
Pender, Niall P.;
McLaughlin, Russell;
Vajda, Alice;
Heverin, Mark;
Lalor, Edmund C.;
Hardiman, Orla;
Nasseroleslami, Bahman

Publication type:

Article

High Incidence of Osteoporosis and Fractures in an Aging Post-Polio Population.

Published in:

European Neurology, 2009, v. 62, n. 6, p. 369, doi. 10.1159/000242444

By:

Mohammad, Ausaf F.;
Khan, Khalid Ali;
Galvin, Leo;
Hardiman, Orla;
O'Connell, Paul G.

Publication type:

Article

Development of an Automated MRI-Based Diagnostic Protocol for Amyotrophic Lateral Sclerosis Using Disease-Specific Pathognomonic Features: A Quantitative Disease-State Classification Study.

Published in:

PLoS ONE, 2016, v. 11, n. 12, p. 1, doi. 10.1371/journal.pone.0167331

By:

Schuster, Christina;
Hardiman, Orla;
Bede, Peter

Publication type:

Article

Measurement of Social Cognition in Amyotrophic Lateral Sclerosis: A Population Based Study.

Published in:

PLoS ONE, 2016, v. 11, n. 8, p. 1, doi. 10.1371/journal.pone.0160850

By:

Burke, Tom;
Pinto-Grau, Marta;
Lonergan, Katie;
Elamin, Marwa;
Bede, Peter;
Costello, Emmet;
Hardiman, Orla;
Pender, Niall

Publication type:

Article

Associations of Electric Shock and Extremely Low-Frequency Magnetic Field Exposure With the Risk of Amyotrophic Lateral Sclerosis: The Euro-MOTOR Project.

Published in:

American Journal of Epidemiology, 2019, v. 188, n. 4, p. 796, doi. 10.1093/aje/kwy287

By:

Peters, Susan;
Visser, Anne E;
D'Ovidio, Fabrizio;
Beghi, Ettore;
Chiò, Adriano;
Logroscino, Giancarlo;
Hardiman, Orla;
Kromhout, Hans;
Huss, Anke;
Veldink, Jan;
Vermeulen, Roel;
Berg, Leonard H van den

Publication type:

Article

Discrete choice experiment for eliciting preference for health services for patients with ALS and their informal caregivers.

Published in:

2021

By:

Tobin, Katy;
Maguire, Sinead;
Corr, Bernie;
Normand, Charles;
Hardiman, Orla;
Galvin, Miriam

Publication type:

journal article

Cerebellar dysfunction in frontotemporal dementia: intra-cerebellar pathology and cerebellar network degeneration.

Published in:

Journal of Neurology, 2025, v. 272, n. 4, p. 1, doi. 10.1007/s00415-025-13046-8

By:

Kleinerova, Jana;
Tahedl, Marlene;
McKenna, Mary Clare;
Garcia-Gallardo, Angela;
Hutchinson, Siobhan;
Hardiman, Orla;
Raoul, Cédric;
Ango, Fabrice;
Schneider, Bernard;
Pradat, Pierre-Francois;
Tan, Ee Ling;
Bede, Peter

Publication type:

Article

Pseudobulbar affect: clinical associations, social impact and quality of life implications - Lessons from PLS.

Published in:

Journal of Neurology, 2025, v. 272, n. 4, p. 1, doi. 10.1007/s00415-025-12971-y

By:

Finegan, Eoin;
Kleinerova, Jana;
Hardiman, Orla;
Hutchinson, Siobhan;
Garcia-Gallardo, Angela;
Tan, Ee Ling;
Bede, Peter

Publication type:

Article

Supra- and infra-tentorial degeneration patterns in primary lateral sclerosis: a multimodal longitudinal neuroradiology study.

Published in:

Journal of Neurology, 2024, v. 271, n. 6, p. 3239, doi. 10.1007/s00415-024-12261-z

By:

Kleinerova, Jana;
Tahedl, Marlene;
Tan, Ee Ling;
Delaney, Siobhan;
Hengeveld, Jennifer C.;
Doherty, Mark A.;
McLaughlin, Russell L.;
Hardiman, Orla;
Chang, Kai Ming;
Finegan, Eoin;
Bede, Peter

Publication type:

Article

Language deficits in primary lateral sclerosis: cortical atrophy, white matter degeneration and functional disconnection between cerebral regions.

Published in:

Journal of Neurology, 2024, v. 271, n. 1, p. 431, doi. 10.1007/s00415-023-11994-7

By:

Tan, Ee Ling;
Tahedl, Marlene;
Lope, Jasmin;
Hengeveld, Jennifer C.;
Doherty, Mark A.;
McLaughlin, Russell L.;
Hardiman, Orla;
Chang, Kai Ming;
Finegan, Eoin;
Bede, Peter

Publication type:

Article

Brainstem–cortex disconnection in amyotrophic lateral sclerosis: bulbar impairment, genotype associations, asymptomatic changes and biomarker opportunities.

Published in:

Journal of Neurology, 2023, v. 270, n. 7, p. 3511, doi. 10.1007/s00415-023-11682-6

By:

Tahedl, Marlene;
Tan, Ee Ling;
Chipika, Rangariroyashe H.;
Hengeveld, Jennifer C.;
Vajda, Alice;
Doherty, Mark A.;
McLaughlin, Russell L.;
Siah, We Fong;
Hardiman, Orla;
Bede, Peter

Publication type:

Article

Patient perspectives on digital healthcare technology in care and clinical trials for motor neuron disease: an international survey.

Published in:

Journal of Neurology, 2022, v. 269, n. 11, p. 6003, doi. 10.1007/s00415-022-11273-x

By:

Helleman, Jochem;
Johnson, Barbara;
Holdom, Cory;
Hobson, Esther;
Murray, Deirdre;
Steyn, Frederik J.;
Ngo, Shyuan T.;
Henders, Anjali;
Lokeshappa, Madhura B.;
Visser-Meily, Johanna M. A.;
van den Berg, Leonard H.;
Hardiman, Orla;
Beelen, Anita;
McDermott, Chris;
van Eijk, Ruben P. A.

Publication type:

Article

Clusters of anatomical disease-burden patterns in ALS: a data-driven approach confirms radiological subtypes.

Published in:

Journal of Neurology, 2022, v. 269, n. 8, p. 4404, doi. 10.1007/s00415-022-11081-3

By:

Bede, Peter;
Murad, Aizuri;
Lope, Jasmin;
Hardiman, Orla;
Chang, Kai Ming

Publication type:

Article

Pathological neural networks and artificial neural networks in ALS: diagnostic classification based on pathognomonic neuroimaging features.

Published in:

Journal of Neurology, 2022, v. 269, n. 5, p. 2440, doi. 10.1007/s00415-021-10801-5

By:

Bede, Peter;
Murad, Aizuri;
Hardiman, Orla

Publication type:

Article

Infratentorial pathology in frontotemporal dementia: cerebellar grey and white matter alterations in FTD phenotypes.

Published in:

Journal of Neurology, 2021, v. 268, n. 12, p. 4687, doi. 10.1007/s00415-021-10575-w

By:

McKenna, Mary Clare;
Chipika, Rangariroyashe H.;
Li Hi Shing, Stacey;
Christidi, Foteini;
Lope, Jasmin;
Doherty, Mark A.;
Hengeveld, Jennifer C.;
Vajda, Alice;
McLaughlin, Russell L.;
Hardiman, Orla;
Hutchinson, Siobhan;
Bede, Peter

Publication type:

Article

The presymptomatic phase of amyotrophic lateral sclerosis: are we merely scratching the surface?

Published in:

2021

By:

Chipika, Rangariroyashe H.;
Siah, We Fong;
McKenna, Mary Clare;
Li Hi Shing, Stacey;
Hardiman, Orla;
Bede, Peter

Publication type:

Literature Review

Cortical progression patterns in individual ALS patients across multiple timepoints: a mosaic-based approach for clinical use.

Published in:

Journal of Neurology, 2021, v. 268, n. 5, p. 1913, doi. 10.1007/s00415-020-10368-7

By:

Tahedl, Marlene;
Chipika, Rangariroyashe H.;
Lope, Jasmin;
Li Hi Shing, Stacey;
Hardiman, Orla;
Bede, Peter

Publication type:

Article

The clinical and radiological profile of primary lateral sclerosis: a population-based study.

Published in:

Journal of Neurology, 2019, v. 266, n. 11, p. 2718, doi. 10.1007/s00415-019-09473-z

By:

Finegan, Eoin;
Chipika, Rangariroyashe H.;
Li Hi Shing, Stacey;
Doherty, Mark A.;
Hengeveld, Jennifer C.;
Vajda, Alice;
Donaghy, Colette;
McLaughlin, Russell L.;
Pender, Niall;
Hardiman, Orla;
Bede, Peter

Publication type:

Article

Longitudinal predictors of caregiver burden in amyotrophic lateral sclerosis: a population-based cohort of patient-caregiver dyads.

Published in:

Journal of Neurology, 2018, v. 265, n. 4, p. 793, doi. 10.1007/s00415-018-8770-6

By:

Burke, Tom;
Hardiman, Orla;
Pinto-Grau, Marta;
Lonergan, Katie;
Heverin, Mark;
Tobin, Katy;
Staines, Anthony;
Galvin, Miriam;
Pender, Niall

Publication type:

Article

Assessing behavioural changes in ALS: cross-validation of ALS-specific measures.

Published in:

Journal of Neurology, 2017, v. 264, n. 7, p. 1397, doi. 10.1007/s00415-017-8536-6

By:

Pinto-Grau, Marta;
Costello, Emmet;
O'connor, Sarah;
Elamin, Marwa;
Burke, Tom;
Heverin, Mark;
Pender, Niall;
Hardiman, Orla

Publication type:

Article

Caregivers of patients with amyotrophic lateral sclerosis: investigating quality of life, caregiver burden, service engagement, and patient survival.

Published in:

Journal of Neurology, 2017, v. 264, n. 5, p. 898, doi. 10.1007/s00415-017-8448-5

By:

Burke, Tom;
Galvin, Miriam;
Pinto-Grau, Marta;
Lonergan, Katie;
Madden, Caoifa;
Mays, Iain;
Carney, Sile;
Hardiman, Orla;
Pender, Niall

Publication type:

Article

Age-period-cohort analysis of trends in amyotrophic lateral sclerosis incidence.

Published in:

Journal of Neurology, 2016, v. 263, n. 10, p. 1919, doi. 10.1007/s00415-016-8215-z

By:

Tobin, Katy;
Gilthorpe, Mark;
Rooney, James;
Heverin, Mark;
Vajda, Alice;
Staines, Anthony;
Hardiman, Orla

Publication type:

Article

Erratum to: Caregiver burden in amyotrophic lateral sclerosis: a cross-sectional investigation of predictors.

Published in:

2015

By:

Burke, Tom;
Elamin, Marwa;
Galvin, Miriam;
Gallagher, Laura;
Hardiman, Orla;
Pender, Niall

Publication type:

Erratum

Predicting prognosis in amyotrophic lateral sclerosis: a simple algorithm.

Published in:

Journal of Neurology, 2015, v. 262, n. 6, p. 1447, doi. 10.1007/s00415-015-7731-6

By:

Elamin, Marwa;
Bede, Peter;
Montuschi, Anna;
Pender, Niall;
Chio, Adriano;
Hardiman, Orla

Publication type:

Article

Caregiver burden in amyotrophic lateral sclerosis: a cross-sectional investigation of predictors.

Published in:

Journal of Neurology, 2015, v. 262, n. 6, p. 1526, doi. 10.1007/s00415-015-7746-z

By:

Burke, Tom;
Elamin, Marwa;
Galvin, Miriam;
Hardiman, Orla;
Pender, Niall

Publication type:

Article

'Sand-watch' spinal cord: a case of inferior cervical spinal cord atrophy.

Published in:

2014

By:

Bede, Peter;
Walsh, Ronan;
Fagan, Andrew;
Hardiman, Orla

Publication type:

Letter

Waterskier's Hirayama syndrome.

Published in:

2011

By:

Bede, Peter;
Bokde, Arun;
Byrne, Susan;
Elamin, Marwa;
Walsh, Ronan;
Hardiman, Orla

Publication type:

Letter

Management of respiratory symptoms in ALS.

Published in:

Journal of Neurology, 2011, v. 258, n. 3, p. 359, doi. 10.1007/s00415-010-5830-y

By:

Hardiman, Orla

Publication type:

Article

Validating population-based registers for ALS: how accurate is death certification?

Published in:

Journal of Neurology, 2010, v. 257, n. 8, p. 1235, doi. 10.1007/s00415-010-5494-7

By:

Yeo, Loraine;
Lynch, Catherine;
Hardiman, Orla

Publication type:

Article

Slow saccades in bulbar-onset motor neurone disease.

Published in:

Journal of Neurology, 2010, v. 257, n. 7, p. 1134, doi. 10.1007/s00415-010-5478-7

By:

Donaghy, Colette;
Pinnock, Ralph;
Abrahams, Sharon;
Cardwell, Chris;
Hardiman, Orla;
Patterson, Victor;
McGivern, R. Canice;
Gibson, J. Mark

Publication type:

Article

Ocular fixation instabilities in motor neurone disease.

Published in:

Journal of Neurology, 2009, v. 256, n. 3, p. 420, doi. 10.1007/s00415-009-0109-x

By:

Donaghy, Colette;
Pinnock, Ralph;
Abrahams, Sharon;
Cardwell, Chris;
Hardiman, Orla;
Patterson, Victor;
McGivern, R. Canice;
Gibson, J. Mark

Publication type:

Article

The management of amyotrophic lateral sclerosis.

Published in:

Journal of Neurology, 2009, v. 256, n. 2, p. 176, doi. 10.1007/s00415-009-0142-9

By:

Phukan, Julie;
Hardiman, Orla

Publication type:

Article

A 45-year history of acquired autoimmune neuromyotonia.

Published in:

Journal of Neurology, 2006, v. 253, n. 9, p. 1243, doi. 10.1007/s00415-006-0172-5

By:

Ryan, Aisling;
Mullins, Gerard;
Scott, Jacqui;
Connolly, Sean;
Hardiman, Orla;
Yilmaz, Emrullah;
Vincent, Angela;
Lynch, Tim

Publication type:

Article

Methodology and Design of a National Epidemiological Study on Adult Neuromuscular Disease.

Published in:

Neuroepidemiology, 2014, v. 43, n. 2, p. 123, doi. 10.1159/000367634

By:

Lefter, Stela;
Hardiman, Orla;
Ryan, aisling M.

Publication type:

Article