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Bitter Melon (Momordica charantia) Extract Inhibits Tumorigenicity and Overcomes Cisplatin-Resistance in Ovarian Cancer Cells Through Targeting AMPK Signaling Cascade.
- Published in:
- Integrative Cancer Therapies, 2016, v. 15, n. 3, p. 376, doi. 10.1177/1534735415611747
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- Article
Oxidative stress activates AMPK in cultured cells primarily by increasing cellular AMP and/or ADP.
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- FEBS Letters, 2014, v. 588, n. 18, p. 3361, doi. 10.1016/j.febslet.2014.07.025
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- Article
Intracellular ATP Influences Synaptic Plasticity in Area CA1 of Rat Hippocampus via Metabolism to Adenosine and Activity-Dependent Activation of Adenosine A<sub>1</sub> Receptors.
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- Journal of Neuroscience, 2011, v. 31, n. 16, p. 6221, doi. 10.1523/JNEUROSCI.4039-10.2011
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- Article
AMPK activation induces mitophagy and promotes mitochondrial fission while activating TBK1 in a PINK1‐Parkin independent manner.
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- FASEB Journal, 2020, v. 34, n. 5, p. 6284, doi. 10.1096/fj.201903051R
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- Article
Changes in mTOR/4‐EBP1 pathway induced by a novel mutation in PRKAG2 gene (864.7).
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- FASEB Journal, 2014, v. 28, p. N.PAG, doi. 10.1096/fasebj.28.1_supplement.864.7
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- Article
The alpha2-5'AMP-activated protein kinase is a site 2 glycogen synthase kinase in skeletal muscle and is responsive to glucose loading.
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- 2004
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- Publication type:
- journal article
The α2-5′ AMP-Activated Protein KinaseIs a Site 2 Glycogen Synthase Kinase in Skeletal Muscle and IsResponsive to Glucose Loading.
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- Diabetes, 2004, v. 53, n. 12, p. 3074, doi. 10.2337/diabetes.53.12.3074
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- Article
Increased phosphorylation of skeletal muscle glycogen synthase at NH2-terminal sites during physiological hyperinsulinemia in type 2 diabetes.
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- 2003
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- Publication type:
- journal article
The antidiabetic drug metformin activates the AMP-activated protein kinase cascade via an adenine nucleotide-independent mechanism.
- Published in:
- 2002
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- Publication type:
- journal article
Glycogen-dependent effects of 5-aminoimidazole-4-carboxamide (AICA)-riboside on AMP-activated protein kinase and glycogen synthase activities in rat skeletal muscle.
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- 2002
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- Publication type:
- journal article
5-aminoimidazole-4-carboxamide riboside mimics the effects of insulin on the expression of the 2 key gluconeogenic genes PEPCK and glucose-6-phosphatase.
- Published in:
- 2000
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- Publication type:
- journal article
AMP-activated protein kinase: a key regulator of energy balance with many roles in human disease.
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- Journal of Internal Medicine, 2014, v. 276, n. 6, p. 543, doi. 10.1111/joim.12268
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- Article
Ion Channel Regulation by AMPK.
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- Annals of the New York Academy of Sciences, 2009, v. 1177, n. 1, p. 89, doi. 10.1111/j.1749-6632.2009.05041.x
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- Article
The LKB1-AMPK-α1 signaling pathway triggers hypoxic pulmonary vasoconstriction downstream of mitochondria.
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- Science Signaling, 2018, v. 11, n. 550, p. 1, doi. 10.1126/scisignal.aau0296
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- Article
AMPK: a cellular energy sensor primarily regulated by AMP.
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- Biochemical Society Transactions, 2014, v. 42, n. 1, p. 71, doi. 10.1042/BST20130244
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- Article
AMPK: opposing the metabolic changes in both tumour cells and inflammatory cells?
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- Biochemical Society Transactions, 2013, v. 41, n. 2, p. 687, doi. 10.1042/BST20120351
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- Article
Dual regulation of the AMP-activated protein kinase provides a novel mechanism for the control of creatine kinase in skeletal muscle.
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- EMBO Journal, 1998, v. 17, n. 6, p. 1688, doi. 10.1093/emboj/17.6.1688
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- Article
The Na+/Glucose Cotransporter Inhibitor Canagliflozin Activates AMPK by Inhibiting Mitochondrial Function and Increasing Cellular AMP Levels.
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- 2016
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- Publication type:
- journal article
Methotrexate Promotes Glucose Uptake and Lipid Oxidation in Skeletal Muscle via AMPK Activation.
- Published in:
- Diabetes, 2015, v. 64, n. 2, p. 360, doi. 10.2337/db14-0508
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- Publication type:
- Article
5-Aminoimidazole-4-Carboxamide 1-β-D-Ribofuranoside Acutely Stimulates Skeletal Muscle 2-Deoxyglucose Uptake in Healthy Men.
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- Diabetes, 2007, v. 56, n. 8, p. 2078, doi. 10.2337/db06-1716
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- Article
BAY-3827 and SBI-0206965: Potent AMPK Inhibitors That Paradoxically Increase Thr172 Phosphorylation.
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- International Journal of Molecular Sciences, 2024, v. 25, n. 1, p. 453, doi. 10.3390/ijms25010453
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- Article
AMPK and the Need to Breathe and Feed: What's the Matter with Oxygen?
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- International Journal of Molecular Sciences, 2020, v. 21, n. 10, p. 3518, doi. 10.3390/ijms21103518
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- Article
Signal transduction: How cells sense energy.
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- Nature, 2011, v. 472, n. 7342, p. 176, doi. 10.1038/472176a
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- Article
AMP-activated protein kinase: the energy charge hypothesis revisited.
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- BioEssays, 2001, v. 23, n. 12, p. 1112, doi. 10.1002/bies.10009
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- Article
AMP-activated protein kinase - An archetypal protein kinase cascade?
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- BioEssays, 1992, v. 14, n. 10, p. 699, doi. 10.1002/bies.950141011
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- Article
AICA riboside both activates AMP-activated protein kinase and competes with adenosine for the nucleoside transporter in the CA1 region of the rat hippocampus.
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- Journal of Neurochemistry, 2004, v. 88, n. 5, p. 1272, doi. 10.1046/j.1471-4159.2003.02253.x
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- Article
AMP-activated protein kinase can be allosterically activated by ADP but AMP remains the key activating ligand.
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- Biochemical Journal, 2024, v. 481, n. 8, p. 587, doi. 10.1042/BCJ20240082
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- Article
Frequent loss-of-function mutations in the AMPK-α2 catalytic subunit suggest a tumour suppressor role in human skin cancers.
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- Biochemical Journal, 2023, v. 480, n. 23, p. 1951, doi. 10.1042/BCJ20230380
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- Article
AMP-activated protein kinase -- a journey from 1 to 100 downstream targets.
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- Biochemical Journal, 2022, v. 479, n. 22, p. 2327, doi. 10.1042/BCJ20220255
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- Article
Isoform-specific AMPK association with TBC1D1 is reduced by a mutation associated with severe obesity.
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- Biochemical Journal, 2018, v. 475, n. 18, p. 2969, doi. 10.1042/BCJ20180475
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- Article
Differential regulation by AMP and ADP of AMPK complexes containing different γ subunit isoforms.
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- Biochemical Journal, 2016, v. 473, n. 2, p. 189, doi. 10.1042/BJ20150910
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- Article
PT-1 selectively activates AMPK-γ 1 complexes in mouse skeletal muscle, but activates all three γ subunit complexes in cultured human cells by inhibiting the respiratory chain.
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- Biochemical Journal, 2015, v. 467, n. 3, p. 461, doi. 10.1042/BJ20141142
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- Article
Phosphorylation by Akt within the ST loop of AMPK-α1 down-regulates its activation in tumour cells.
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- Biochemical Journal, 2014, v. 459, n. 2, p. 275, doi. 10.1042/BJ20131344
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- Article
Publisher Correction: LKB1 is the gatekeeper of carotid body chemosensing and the hypoxic ventilatory response.
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- 2022
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- Correction Notice
LKB1 is the gatekeeper of carotid body chemosensing and the hypoxic ventilatory response.
- Published in:
- Communications Biology, 2022, v. 5, n. 1, p. 1, doi. 10.1038/s42003-022-03583-7
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- Article
Intramyocellular Lipid Content and Molecular Adaptations in Response to a 1-Week High-Fat Diet<sup>**</sup>.
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- Obesity (19307381), 2005, v. 13, n. 12, p. 2088, doi. 10.1038/oby.2005.259
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- Article
A new protein kinase cascade.
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- Nature Reviews Molecular Cell Biology, 2014, v. 15, n. 4, p. 223, doi. 10.1038/nrm3771
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- Article
AMPK: a nutrient and energy sensor that maintains energy homeostasis.
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- Nature Reviews Molecular Cell Biology, 2012, v. 13, n. 4, p. 251, doi. 10.1038/nrm3311
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- Article
AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy.
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- Nature Reviews Molecular Cell Biology, 2007, v. 8, n. 10, p. 774, doi. 10.1038/nrm2249
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- Article
Normal hypertrophy accompanied by phosphoryation and activation of AMP-activated protein kinase α1 following overload in LKB1 knockout mice.
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- Journal of Physiology, 2008, v. 586, n. 6, p. 1731, doi. 10.1113/jphysiol.2007.143685
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- Publication type:
- Article
De-phosphorylation of MyoD is linking nerve-evoked activity to fast myosin heavy chain expression in rodent adult skeletal muscle.
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- Journal of Physiology, 2007, v. 584, n. 2, p. 637, doi. 10.1113/jphysiol.2007.141457
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- Article
AMP-activated protein kinase – development of the energy sensor concept.
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- Journal of Physiology, 2006, v. 574, n. 1, p. 7, doi. 10.1113/jphysiol.2006.108944
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- Publication type:
- Article
Phenformin and 5-aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR) activation of AMP-activated protein kinase inhibits transepithelial Na<sup>+</sup> transport across H441 lung cells.
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- Journal of Physiology, 2005, v. 566, n. 3, p. 781, doi. 10.1113/jphysiol.2005.088674
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- Publication type:
- Article
Regulation of hormone-sensitive lipase activity and Ser<sup>563</sup> and Ser<sup>565</sup> phosphorylation in human skeltal muscle during exercise.
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- Journal of Physiology, 2004, v. 560, n. 2, p. 551, doi. 10.1113/jphysiol.2004.066480
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- Publication type:
- Article
Role of 5′AMP-activated protein kinase in glycogen synthase activity and glucose utilization: insights from patients with McArdle's disease.
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- Journal of Physiology, 2002, v. 541, n. 3, p. 979, doi. 10.1113/jphysiol.2002.018044
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- Publication type:
- Article
Glycogen Content Regulates Peroxisome Proliferator Activated Receptor-∂ (PPAR-∂) Activity in Rat Skeletal Muscle.
- Published in:
- PLoS ONE, 2013, v. 8, n. 10, p. 1, doi. 10.1371/journal.pone.0077200
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- Article
Energy sensing by the AMP-activated protein kinase and its effects on muscle metabolism.
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- Proceedings of the Nutrition Society, 2011, v. 70, n. 1, p. 92, doi. 10.1017/S0029665110003915
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- Article
Metabolism of inflammation limited by AMPK and pseudo-starvation.
- Published in:
- Nature, 2013, v. 493, n. 7432, p. 346, doi. 10.1038/nature11862
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- Article
How I Became a Biochemist.
- Published in:
- IUBMB Life, 2007, v. 59, n. 12, p. 793, doi. 10.1080/15216540701556873
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- Article
AMPK and autophagy get connected.
- Published in:
- EMBO Journal, 2011, v. 30, n. 12, p. 2511, doi. 10.1038/emboj.2011.175
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- Article