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Brain high-throughput multi-omics data reveal molecular heterogeneity in Alzheimer's disease.
- Published in:
- PLoS Biology, 2024, v. 22, n. 4, p. 1, doi. 10.1371/journal.pbio.3002607
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- Publication type:
- Article
Cross‐omics integration analysis revels synaptic dysregulation across brain regions at later stages of Alzheimer disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077100
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- Publication type:
- Article
circRNAs mediate the effect of chronic lysosomal dysfunction on Alzheimer's disease pathology.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.072168
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- Publication type:
- Article
A cell‐autonomous role of DNAJC5 in microglial‐mediated proteostasis in Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.071075
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- Publication type:
- Article
Leveraging systems biology approaches and single‐nucleus RNA‐seq to study sex differences in AD.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076877
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- Publication type:
- Article
Microglia transcriptional heterogeneity across human and experimental models.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076619
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- Publication type:
- Article
Ambient RNA from CSF to capture brain cell‐type signatures in AD and other neurodegenerative diseases.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077297
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- Publication type:
- Article
Leveraging systems biology approaches and single‐nucleus RNA‐seq to study sex differences in AD.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076877
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- Publication type:
- Article
Microglia transcriptional heterogeneity across human and experimental models.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.076619
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- Publication type:
- Article
Ambient RNA from CSF to capture brain cell‐type signatures in AD and other neurodegenerative diseases.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.077297
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- Publication type:
- Article
A transcriptome association study of AD risk genes in the pathogenesis of Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.065243
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- Article
Identification of genetic regulators of human metabolites in CSF.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.064147
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- Publication type:
- Article
Mendelian randomization and genetic colocalization infer the effects of the multi-tissue proteome on 211 complex disease-related phenotypes.
- Published in:
- Genome Medicine, 2022, v. 14, n. 1, p. 1, doi. 10.1186/s13073-022-01140-9
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- Publication type:
- Article
Defective proteostasis in induced pluripotent stem cell models of frontotemporal lobar degeneration.
- Published in:
- Translational Psychiatry, 2022, v. 12, n. 1, p. 1, doi. 10.1038/s41398-022-02274-5
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- Publication type:
- Article
Characterizing Disrupted Cellular Crosstalk Signaling Networks in Alzheimer's Disease Using Single‐Nuclei Transcriptomics.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.062304
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- Publication type:
- Article
Genetic and glial heterogeneity in Alzheimer disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.061185
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- Publication type:
- Article
Pleiotropic effect of LRRK2 on Parkinson‐associated proteins and processing of pathological alpha‐synuclein in myeloid cells.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 4, p. 1, doi. 10.1002/alz.063954
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- Article
KDM6A expression is associated with a sex‐disease interaction in activated microglia.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2022, v. 18, n. 3, p. 1, doi. 10.1002/alz.065829
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- Publication type:
- Article
Preclinical Alzheimer's disease biomarkers accurately predict cognitive and neuropathological outcomes.
- Published in:
- 2022
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- Publication type:
- journal article
Weakly activated core neuroinflammation pathways were identified as a central signaling mechanism contributing to the chronic neurodegeneration in Alzheimer's disease.
- Published in:
- Frontiers in Aging Neuroscience, 2022, v. 14, p. 1, doi. 10.3389/fnagi.2022.935279
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- Publication type:
- Article
Multi-ancestry GWAS reveals excitotoxicity associated with outcome after ischaemic stroke.
- Published in:
- Brain: A Journal of Neurology, 2022, v. 145, n. 7, p. 2394, doi. 10.1093/brain/awac080
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- Publication type:
- Article
Circular RNA detection identifies circPSEN1 alterations in brain specific to autosomal dominant Alzheimer's disease.
- Published in:
- Acta Neuropathologica Communications, 2022, v. 10, n. 1, p. 1, doi. 10.1186/s40478-022-01328-5
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- Publication type:
- Article
Murine roseolovirus does not accelerate amyloid-β pathology and human roseoloviruses are not over-represented in Alzheimer disease brains.
- Published in:
- Molecular Neurodegeneration, 2022, v. 17, n. 1, p. 1, doi. 10.1186/s13024-021-00514-8
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- Publication type:
- Article
Prediction of Alzheimer disease using plasma RNA sequences from dementia genes.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.049885
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- Publication type:
- Article
Multi‐tissue proteomic profiling for genetically defined Alzheimer disease cases.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.054301
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- Publication type:
- Article
Single nuclei RNA‐sequencing of GWAS loci variant carriers elucidates cell‐types and transcriptional profile alterations associated with Alzheimer disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.054402
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- Publication type:
- Article
Multi‐omics data integration reveals clinically meaningful molecular profiles of Alzheimer disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.052942
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- Publication type:
- Article
Functional exploration of AGFG2, a novel player in the pathology of Alzheimer disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.054240
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- Publication type:
- Article
Stem cell models of primary tauopathies reveal defects in synaptic function.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.054566
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- Publication type:
- Article
Impact of MAPT mutations on transcriptomic signatures of FTLD brains and patient‐derived pluripotent cell models.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.054570
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- Publication type:
- Article
Profiling the metabolic landscape of AD.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.050086
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- Publication type:
- Article
LMNA‐mediated nucleoskeleton dysregulation in Alzheimer disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.054396
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- Publication type:
- Article
Genome‐wide DNA methylation analysis of autosomal dominantly inherited and sporadic Alzheimer disease brains.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.053502
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- Publication type:
- Article
Genome‐wide scan of Alzheimer disease cohort identifies genetic loci associated with human brain metabolite levels.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.051756
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- Publication type:
- Article
Multi‐omics approaches reveal a link between the MS4A gene loci, TREM2, and microglia function.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 3, p. 1, doi. 10.1002/alz.054553
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- Publication type:
- Article
Impact of MAPT mutations on transcriptomic signatures of FTLD brains and patient‐derived pluripotent cell models.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.058313
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- Publication type:
- Article
Astrocytic BMAL1 regulates protein aggregation in mouse models of alpha‐synuclein and tau pathology.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, p. 1, doi. 10.1002/alz.058631
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- Publication type:
- Article
Alzheimer's disease alters oligodendrocytic glycolytic and ketolytic gene expression.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2021, v. 17, n. 9, p. 1474, doi. 10.1002/alz.12310
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- Publication type:
- Article
Alzheimer's Disease Alters Oligodendrocytic Glycolytic and Ketolytic Gene Expression.
- Published in:
- FASEB Journal, 2021, v. 35, p. N.PAG, doi. 10.1096/fasebj.2021.35.S1.02461
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- Publication type:
- Article
A Mendelian randomization approach to characterize overlap in the pathophysiology of neurological disorders: Genetics/omics and systems biology.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.044238
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- Publication type:
- Article
Identification of blood eQTLs for AD risk loci: Genetics/genetic factors of Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043801
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- Publication type:
- Article
Ascertaining perturbations in microglial expression profiles using single‐nuclei RNA‐seq from human brains: Genetics/genetic factors of Alzheimer's disease.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.046024
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- Publication type:
- Article
Single‐nuclei RNA‐seq of brains carriers of high‐risk variants and Mendelian mutations: Genetics: Genetics and omics of AD I.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043125
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- Publication type:
- Article
Alzheimer‐associated circular RNA circHOMER1 regulates synaptic gene expression and cognition: Molecular and cell biology: Neurodegeneration versus neuroprotection.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.042335
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- Publication type:
- Article
A comprehensive analysis of dementia cerebrospinal fluid biomarkers using GWAs, polygenic risk scores and Mendelian randomization in Parkinson's disease: Genetics/atypical and other dementias.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043233
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- Publication type:
- Article
Prediction of Alzheimer's disease using plasma RNA sequences: Biomarkers (non‐neuroimaging) / Novel biomarkers.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043273
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- Publication type:
- Article
Late‐onset Alzheimer's disease‐associated gene, CPAMD8, increases B‐CTF and affects APP processing through regulation of the autophagy‐lysosome pathway: Molecular and cell biology: Endo‐lysosomal/trafficking dysfunction.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.040559
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- Publication type:
- Article
Identification of multi‐issue protein quantitative trait loci (pQTLs) for Alzheimer disease: Genetics/omics and systems biology.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.040496
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- Publication type:
- Article
Proteogenomic analysis of cerebrospinal fluid reveals causal role of proteins from the autophagy‐lysosome pathway in Parkinson's disease: Genetics: Genetics of cognitive aging, other dementia, and endophenotypes.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043422
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- Publication type:
- Article
Multiomics approaches reveal a link between the MS4A gene loci, TREM2, and microglia function: Genetics/omics and systems biology.
- Published in:
- Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2020, v. 16, n. 11, p. 1, doi. 10.1002/alz.043592
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- Publication type:
- Article