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The H3K9 dimethyltransferases EHMT1/2 protect against pathological cardiac hypertrophy.
Published in:
2017
By:
- Thienpont, Bernard;
- Aronsen, Jan Magnus;
- Robinson, Emma Louise;
- Hanneke Okkenhaug;
- Loche, Elena;
- Ferrini, Arianna;
- Brien, Patrick;
- Alkass, Kanar;
- Tomasso, Antonio;
- Agrawal, Asmita;
- Bergmann, Olaf;
- Sjaastad, Ivar;
- Reik, Wolf;
- Roderick, Hywel Llewelyn;
- Okkenhaug, Hanneke
Publication type:
journal article
Satellite repeat transcripts modulate heterochromatin condensates and safeguard chromosome stability in mouse embryonic stem cells.
Published in:
Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-31198-3
By:
- Novo, Clara Lopes;
- Wong, Emily V.;
- Hockings, Colin;
- Poudel, Chetan;
- Sheekey, Eleanor;
- Wiese, Meike;
- Okkenhaug, Hanneke;
- Boulton, Simon J.;
- Basu, Srinjan;
- Walker, Simon;
- Kaminski Schierle, Gabriele S.;
- Narlikar, Geeta J.;
- Rugg-Gunn, Peter J.
Publication type:
Article
IKKα plays a major role in canonical NF-κB signalling in colorectal cells.
Published in:
Biochemical Journal, 2022, v. 479, n. 3, p. 305, doi. 10.1042/BCJ20210783
By:
- Prescott, Jack A.;
- Balmanno, Kathryn;
- Mitchell, Jennifer P.;
- Okkenhaug, Hanneke;
- Cook, Simon J.
Publication type:
Article
Multi-omic rejuvenation of human cells by maturation phase transient reprogramming.
Published in:
eLife, 2022, p. 1, doi. 10.7554/eLife.71624
By:
- Gill, Diljeet;
- Parry, Aled;
- Santos, Fátima;
- Okkenhaug, Hanneke;
- Todd, Christopher D.;
- Hernando-Herraez, Irene;
- Stubbs, Thomas M.;
- Milagre, Inês;
- Reik, Wolf
Publication type:
Article
BAP1/ASXL complex modulation regulates epithelial-mesenchymal transition during trophoblast differentiation and invasion.
Published in:
eLife, 2021, p. 1, doi. 10.7554/eLife.63254
By:
- Perez-Garcia, Vicente;
- Lea, Georgia;
- Lopez-Jimenez, Pablo;
- Okkenhaug, Hanneke;
- Burton, Graham J.;
- Moffett, Ashley;
- Turco, Margherita Y.;
- Hemberger, Myriam
Publication type:
Article
The Rac-GEF Tiam1 controls integrin-dependent neutrophil responses.
Published in:
Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1223653
By:
- Hornigold, Kirsti;
- Baker, Martin J.;
- Machin, Polly A.;
- Chetwynd, Stephen A.;
- Johnsson, Anna-Karin;
- Pantarelli, Chiara;
- Islam, Priota;
- Stammers, Melanie;
- Crossland, Laraine;
- Oxley, David;
- Okkenhaug, Hanneke;
- Walker, Simon;
- Walker, Rachael;
- Segonds-Pichon, Anne;
- Fukui, Yoshinori;
- Malliri, Angeliki;
- Welch, Heidi C. E.
Publication type:
Article
Dock2 generates characteristic spatiotemporal patterns of Rac activity to regulate neutrophil polarisation, migration and phagocytosis.
Published in:
Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1180886
By:
- Machin, Polly A.;
- Johnsson, Anna-Karin E.;
- Massey, Ellie J.;
- Pantarelli, Chiara;
- Chetwynd, Stephen A.;
- Chu, Julia Y.;
- Hanneke Okkenhaug;
- Segonds-Pichon, Anne;
- Walker, Simon;
- Angeliki Malliri;
- Yoshinori Fukui;
- Welch, Heidi C. E.
Publication type:
Article
Neuronal HSF-1 coordinates the propagation of fat desaturation across tissues to enable adaptation to high temperatures in C. elegans.
Published in:
PLoS Biology, 2021, v. 19, n. 11, p. 1, doi. 10.1371/journal.pbio.3001431
By:
- Chauve, Laetitia;
- Hodge, Francesca;
- Murdoch, Sharlene;
- Masoudzadeh, Fatemah;
- Mann, Harry-Jack;
- Lopez-Clavijo, Andrea;
- Okkenhaug, Hanneke;
- West, Greg;
- Sousa, Bebiana C.;
- Segonds-Pichon, Anne;
- Li, Cheryl;
- Wingett, Steven;
- Kienberger, Hermine;
- Kleigrewe, Karin;
- De Bono, Mario;
- Wakelam, Michael;
- Casanueva, Olivia
Publication type:
Article
Reporter cell lines to screen for inhibitors or regulators of the KRAS-RAF-MEK1/2-ERK1/2 pathway.
Published in:
Biochemical Journal, 2024, v. 481, n. 6, p. 405, doi. 10.1042/BCJ20240015
By:
- Weatherdon, Laura;
- Stuart, Kate;
- Cassidy, Megan;
- de la Gándara, Alberto Moreno;
- Okkenhaug, Hanneke;
- Muellener, Markus;
- Mckenzie, Grahame;
- Cook, Simon J.;
- Gilley, Rebecca
Publication type:
Article
Autophagy initiation by ULK complex assembly on ER tubulovesicular regions marked by ATG9 vesicles.
Published in:
Nature Communications, 2016, v. 7, n. 8, p. 12420, doi. 10.1038/ncomms12420
By:
- Karanasios, Eleftherios;
- Walker, Simon A.;
- Okkenhaug, Hanneke;
- Manifava, Maria;
- Hummel, Eric;
- Zimmermann, Hans;
- Ahmed, Qashif;
- Domart, Marie-Charlotte;
- Collinson, Lucy;
- Ktistakis, Nicholas T.
Publication type:
Article
The human CIC-4 protein, a member of the CLC chloride channel/transporter family, is localized to the endoplasmic reticulum by its N-terminus.
Published in:
FASEB Journal, 2006, v. 20, n. 13, p. 2390, doi. 10.1096/fj.05-5588fje
By:
- Okkenhaug, Hanneke;
- Weylandt, Karsten-Henrich;
- Carmena, David;
- Wells, Dominic J.;
- Higgins, Christopher F.;
- Sardini, Alessandro
Publication type:
Article
Rhabdomere biogenesis in Drosophila photoreceptors is acutely sensitive to phosphatidic acid levels.
Published in:
Journal of Cell Biology, 2009, v. 185, n. 1, p. 129, doi. 10.1083/jcb.200807027
By:
- Raghu, Padinjat;
- Coessens, Elise;
- Manifava, Maria;
- Georgiev, Plamen;
- Pettitt, Trevor;
- Wood, Eleanor;
- Garcia-Murillas, Isaac;
- Okkenhaug, Hanneke;
- Trivedi, Deepti;
- Qifeng Zhang;
- Razzaq, Azam;
- Zaid, Ola;
- Wakelam, Michael;
- O'Kane, Cahir J.;
- Ktistakis, Nicholas
Publication type:
Article
A cell-based bioluminescence assay reveals dose-dependent and contextual repression of AP-1-driven gene expression by BACH2.
Published in:
Scientific Reports, 2020, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41598-020-75732-z
By:
- Vardaka, Panagiota;
- Lozano, Teresa;
- Bot, Christopher;
- Ellery, Jonathan;
- Whiteside, Sarah K.;
- Imianowski, Charlotte J.;
- Farrow, Stuart;
- Walker, Simon;
- Okkenhaug, Hanneke;
- Yang, Jie;
- Okkenhaug, Klaus;
- Kuo, Paula;
- Roychoudhuri, Rahul
Publication type:
Article
MSK-Mediated Phosphorylation of Histone H3 Ser28 Couples MAPK Signalling with Early Gene Induction and Cardiac Hypertrophy.
Published in:
Cells (2073-4409), 2022, v. 11, n. 4, p. 604, doi. 10.3390/cells11040604
By:
- Robinson, Emma L.;
- Drawnel, Faye M.;
- Mehdi, Saher;
- Archer, Caroline R.;
- Liu, Wei;
- Okkenhaug, Hanneke;
- Alkass, Kanar;
- Aronsen, Jan Magnus;
- Nagaraju, Chandan K.;
- Sjaastad, Ivar;
- Sipido, Karin R.;
- Bergmann, Olaf;
- Arthur, J. Simon C.;
- Wang, Xin;
- Roderick, H. Llewelyn
Publication type:
Article
Smarcad1 mediates microbiota-induced inflammation in mouse and coordinates gene expression in the intestinal epithelium.
Published in:
Genome Biology, 2020, v. 21, n. 1, p. 1, doi. 10.1186/s13059-020-01976-7
By:
- Kazakevych, Juri;
- Denizot, Jérémy;
- Liebert, Anke;
- Portovedo, Mariana;
- Mosavie, Mia;
- Jain, Payal;
- Stellato, Claudia;
- Fraser, Claire;
- Corrêa, Renan Oliveira;
- Célestine, Marina;
- Mattiuz, Raphaël;
- Okkenhaug, Hanneke;
- Miller, J. Ross;
- Vinolo, Marco Aurélio Ramirez;
- Veldhoen, Marc;
- Varga-Weisz, Patrick
Publication type:
Article
The GPCR adaptor protein Norbin regulates S1PR1 trafficking and the morphology, cell cycle and survival of PC12 cells.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-45148-6
By:
- Johansen, Valdemar B. I.;
- Hampson, Elizabeth;
- Tsonou, Elpida;
- Pantarelli, Chiara;
- Chu, Julia Y.;
- Crossland, Laraine;
- Okkenhaug, Hanneke;
- Massey, Andrew J.;
- Hornigold, David C.;
- Welch, Heidi C. E.;
- Chetwynd, Stephen A.
Publication type:
Article

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