Works matching AU Handa, James T.

Results: 46

βA3/A1-crystallin regulates apical polarity and EGFR endocytosis in retinal pigmented epithelial cells.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-02386-6

By:

Shang, Peng;
Stepicheva, Nadezda;
Teel, Kenneth;
McCauley, Austin;
Fitting, Christopher Scott;
Hose, Stacey;
Grebe, Rhonda;
Yazdankhah, Meysam;
Ghosh, Sayan;
Liu, Haitao;
Strizhakova, Anastasia;
Weiss, Joseph;
Bhutto, Imran A.;
Lutty, Gerard A.;
Jayagopal, Ashwath;
Qian, Jiang;
Sahel, José-Alain;
Samuel Zigler, J.;
Handa, James T.;
Sergeev, Yuri

Publication type:

Article

NRF2 plays a protective role in diabetic retinopathy in mice.

Published in:

Diabetologia, 2014, v. 57, n. 1, p. 204, doi. 10.1007/s00125-013-3093-8

By:

Xu, Zhenhua;
Wei, Yanhong;
Gong, Junsong;
Cho, Hongkwan;
Park, James K.;
Sung, Ee-Rah;
Huang, Hu;
Wu, Lijuan;
Eberhart, Charles;
Handa, James T.;
Du, Yunpeng;
Kern, Timothy S.;
Thimmulappa, Rajesh;
Barber, Alistair J.;
Biswal, Shyam;
Duh, Elia J.

Publication type:

Article

Examining the effects of cigarette smoke on mouse lens through a multi OMIC approach.

Published in:

Scientific Reports, 2021, v. 11, n. 1, p. 1, doi. 10.1038/s41598-021-95013-7

By:

Khan, Shahid Y.;
Ali, Muhammad;
Jang, Yura;
Ryu, Taekyung;
Schwab, Andrew J.;
Ingram, Brian O.;
Cable, Peter H.;
Na, Chan Hyun;
Handa, James T.;
Riazuddin, S. Amer

Publication type:

Article

Hypoxia Promotes Uveal Melanoma Invasion through Enhanced Notch and MAPK Activation.

Published in:

PLoS ONE, 2014, v. 9, n. 8, p. 1, doi. 10.1371/journal.pone.0105372

By:

Asnaghi, Laura;
Lin, Michael H.;
Lim, Kah Suan;
Lim, Kah Jing;
Tripathy, Arushi;
Wendeborn, Murilo;
Merbs, Shannath L.;
Handa, James T.;
Sodhi, Akrit;
Bar, Eli E.;
Eberhart, Charles G.

Publication type:

Article

T Cells and Macrophages Responding to Oxidative Damage Cooperate in Pathogenesis of a Mouse Model of Age-Related Macular Degeneration.

Published in:

PLoS ONE, 2014, v. 9, n. 2, p. 1, doi. 10.1371/journal.pone.0088201

By:

Cruz-Guilloty, Fernando;
Saeed, Ali M.;
Duffort, Stephanie;
Cano, Marisol;
Ebrahimi, Katayoon B.;
Ballmick, Asha;
Tan, Yaohong;
Wang, Hua;
Laird, James M.;
Salomon, Robert G.;
Handa, James T.;
Perez, Victor L.

Publication type:

Article

Poly(β-Amino Ester)-Nanoparticle Mediated Transfection of Retinal Pigment Epithelial Cells In Vitro and In Vivo.

Published in:

PLoS ONE, 2012, v. 7, n. 5, p. 1, doi. 10.1371/journal.pone.0037543

By:

Sunshine, Joel C.;
Sunshine, Sarah B.;
Bhutto, Imran;
Handa, James T.;
Green, Jordan J.

Publication type:

Article

Changes in Retinal Pigment Epithelium Related to Cigarette Smoke: Possible Relevance to Smoking as a Risk Factor for Age-Related Macular Degeneration.

Published in:

PLoS ONE, 2009, v. 4, n. 4, p. 1, doi. 10.1371/journal.pone.0005304

By:

Ai Ling Wang;
Lukas, Thomas J.;
Ming Yuan;
Nga Du;
Handa, James T.;
Neufeld, Arthur H.

Publication type:

Article

Chronic Cigarette Smoke Causes Oxidative Damage and Apoptosis to Retinal Pigmented Epithelial Cells in Mice.

Published in:

PLoS ONE, 2008, v. 3, n. 9, p. 1, doi. 10.1371/journal.pone.0003119

By:

Fujihara, Masashi;
Nagai, Norihiro;
Sussan, Thomas E.;
Biswal, Shyam;
Handa, James T.

Publication type:

Article

LIPOPROTEIN(a) WITH AN INTACT LYSINE BINDING SITE PROTECTS THE RETINA FROM AN AGE- RELATED MACULAR DEGENERATION PHENOTYPE IN MICE (AN AMERICAN OPHTHALMOLOGICAL SOCIETY THESIS).

Published in:

Transactions of the American Ophthalmological Society, 2015, v. 113, p. T5-1

By:

Handa, James T.;
Mizuki Tagami;
Ebrahimi, Katayoon;
Leibundgut, Gregor;
Janiak, Anna;
Witztum, Joseph L.;
Sotirios Tsimikas

Publication type:

Article

The Role of Vitrectomy in Rhegmatogenous Retinal Detachment.

Published in:

Seminars in Ophthalmology, 1995, v. 10, n. 1, p. 9, doi. 10.3109/08820539509059975

By:

Handa, James T.

Publication type:

Article

Reducing Akt2 in retinal pigment epithelial cells causes a compensatory increase in Akt1 and attenuates diabetic retinopathy.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33773-0

By:

Liu, Haitao;
Stepicheva, Nadezda A.;
Ghosh, Sayan;
Shang, Peng;
Chowdhury, Olivia;
Daley, Rachel A.;
Yazdankhah, Meysam;
Gupta, Urvi;
Hose, Stacey L.;
Valapala, Mallika;
Fitting, Christopher Scott;
Strizhakova, Anastasia;
Shan, Yang;
Feenstra, Derrick;
Sahel, José-Alain;
Jayagopal, Ashwath;
Handa, James T.;
Zigler Jr., J. Samuel;
Fort, Patrice E.;
Sodhi, Akrit

Publication type:

Article

Lipids, Lipoproteins, and Age-Related Macular Degeneration.

Published in:

Journal of Lipids, 2011, p. 1, doi. 10.1155/2011/802059

By:

Ebrahimi, Katayoon B.;
Handa, James T.

Publication type:

Article

Mitophagy initiates retrograde mitochondrial-nuclear signaling to guide retinal pigment cell heterogeneity.

Published in:

Autophagy, 2023, v. 19, n. 3, p. 966, doi. 10.1080/15548627.2022.2109286

By:

Datta, Sayantan;
Cano, Marisol;
Satyanarayana, Ganesh;
Liu, Tongyun;
Wang, Lei;
Wang, Jie;
Cheng, Jie;
Itoh, Kie;
Sharma, Anjali;
Bhutto, Imran;
Kannan, Rangaramanujam;
Qian, Jiang;
Sinha, Debasish;
Handa, James T.

Publication type:

Article

BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes.

Published in:

Autophagy, 2021, v. 17, n. 10, p. 3140, doi. 10.1080/15548627.2020.1871204

By:

Yazdankhah, Meysam;
Ghosh, Sayan;
Shang, Peng;
Stepicheva, Nadezda;
Hose, Stacey;
Liu, Haitao;
Chamling, Xitiz;
Tian, Shenghe;
Sullivan, Mara L.G.;
Calderon, Michael Joseph;
Fitting, Christopher S.;
Weiss, Joseph;
Jayagopal, Ashwath;
Handa, James T.;
Sahel, José-Alain;
Zigler jr., J. Samuel;
Kinchington, Paul R.;
Zack, Donald J.;
Sinha, Debasish

Publication type:

Article

Modulating EGFR-MTORC1-autophagy as a potential therapy for persistent fetal vasculature (PFV) disease.

Published in:

Autophagy, 2020, v. 16, n. 6, p. 1130, doi. 10.1080/15548627.2019.1660545

By:

Yazdankhah, Meysam;
Shang, Peng;
Ghosh, Sayan;
Bhutto, Imran A.;
Stepicheva, Nadezda;
Grebe, Rhonda;
Hose, Stacey;
Weiss, Joseph;
Luo, Tianqi;
Mishra, Subrata;
Riazuddin, S. Amer;
Ghosh, Arkasubhra;
Handa, James T.;
Lutty, Gerard A.;
Zigler, J. Samuel;
Sinha, Debasish

Publication type:

Article

Visual acuity after cataract surgery in Macular Telangiectasia Type 2 Stage 3 to 5.

Published in:

International Journal of Retina & Vitreous, 2022, v. 8, n. 1, p. 1, doi. 10.1186/s40942-022-00386-0

By:

Heng, Jacob S.;
Arevalo, J. Fernando;
Handa, James T.

Publication type:

Article

Repair of progressive retinal detachment complicating degenerative retinoschisis: surgical management and outcomes in phakic eyes.

Published in:

International Journal of Retina & Vitreous, 2021, v. 7, n. 1, p. 1, doi. 10.1186/s40942-021-00344-2

By:

Beatson, Bradley;
Pham, Alex;
Ong, Sally S.;
Ahmed, Ishrat;
Arevalo, J. Fernando;
Handa, James T.

Publication type:

Article

Vascular disrupting agent for neovascular age related macular degeneration: a pilot study of the safety and efficacy of intravenous combretastatin a-4 phosphate.

Published in:

BMC Pharmacology & Toxicology, 2013, v. 14, n. 1, p. 1, doi. 10.1186/2050-6511-14-7

By:

Ibrahim, Mohamed A.;
Do, Diana V.;
Sepah, Yasir J.;
Shah, Syed M.;
Van Anden, Elizabeth;
Hafiz, Gulnar;
Donahue, J. Kevin;
Rivers, Richard;
Balkissoon, Jai;
Handa, James T.;
Campochiaro, Peter A.;
Quan Dong Nguyen

Publication type:

Article

ATAC-Seq analysis reveals a widespread decrease of chromatin accessibility in age-related macular degeneration.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-03856-y

By:

Jie Wang;
Zibetti, Cristina;
Peng Shang;
Sripathi, Srinivasa R.;
Pingwu Zhang;
Cano, Marisol;
Thanh Hoang;
Shuli Xia;
Hongkai Ji;
Merbs, Shannath L.;
Zack, Donald J.;
Handa, James T.;
Sinha, Debasish;
Blackshaw, Seth;
Jiang Qian

Publication type:

Article

Symptom-Based Risk Factors for Retinal Tears and Detachments in Suspected Posterior Vitreous Detachment.

Published in:

Ophthalmologica, 2022, v. 245, n. 6, p. 570, doi. 10.1159/000527295

By:

Ahmad, Meleha T.;
Sein, Julia;
Wang, Jiangxia;
Scott, Adrienne W.;
Ramroop, Janelle;
Jiramongkolchai, Kim;
Zimmer-Galler, Ingrid E.;
Handa, James T.;
Arevalo, J. Fernando

Publication type:

Article

Retinal Microenvironment Imbalance in Dry Age-Related Macular Degeneration: A Mini-Review.

Published in:

Gerontology, 2013, v. 59, n. 4, p. 297, doi. 10.1159/000346169

By:

Barnett, Brad P.;
Handa, James T.

Publication type:

Article

Neighborhood-Level Social Determinants of Health and Presenting Characteristics for Rhegmatogenous Retinal Detachments.

Published in:

JAMA Ophthalmology, 2024, v. 142, n. 9, p. 845, doi. 10.1001/jamaophthalmol.2024.2889

By:

Ong, Sally S.;
Tran, Diep;
Westlund, Erik;
Ahmed, Ishrat;
Russell, Gregory B.;
Gonzales, Anthony;
Handa, James T.;
Cai, Cindy X.

Publication type:

Article

Frequency of Urgent or Emergent Vitreoretinal Surgical Procedures in the United States During the COVID-19 Pandemic.

Published in:

2021

By:

Breazzano, Mark P.;
Nair, Archana A.;
Arevalo, J. Fernando;
Barakat, Mark R.;
Berrocal, Audina M.;
Chang, Jonathan S.;
Chen, Andrew;
Eliott, Dean;
Garg, Sunir J.;
Ghadiali, Quraish;
Gong, Dan;
Grewal, Dilraj S.;
Handa, James T.;
Henderson, Matthew;
Leiderman, Yannek I.;
Leng, Theodore;
Mannina, Amar;
Mendel, Thomas A.;
Mustafi, Debarshi;
de Koo, Lisa C. Olmos

Publication type:

journal article

Lysosomal-mediated waste clearance in retinal pigment epithelial cells is regulated by CRYBA1/βA3/A1-crystallin via V-ATPase-MTORC1 signaling.

Published in:

Autophagy, 2014, v. 10, n. 3, p. 480, doi. 10.4161/auto.27292

By:

Valapala, Mallika;
Wilson, Christine;
Hose, Stacey;
Bhutto, Imran A.;
Grebe, Rhonda;
Dong, Aling;
Greenbaum, Seth;
Gu, Limin;
Sengupta, Samhita;
Cano, Marisol;
Hackett, Sean;
Guotong Xu;
Lutty, Gerard A.;
Dong, Lijin;
Sergeev, Yuri;
Handa, James T.;
Campochiaro, Peter;
Wawrousek, Eric;
Zigler Jr, J. Samuel;
Sinha, Debasish

Publication type:

Article

Apolipoprotein B100 secretion by cultured ARPE-19 cells is modulated by alteration of cholesterol levels.

Published in:

Journal of Neurochemistry, 2010, v. 114, n. 6, p. 1734, doi. 10.1111/j.1471-4159.2010.06884.x

By:

Tinghuai Wu;
Fujihara, Masashi;
Tian, Jane;
Jovanovic, Miroslava;
Grayson, Celene;
Cano, Marisol;
Gehlbach, Peter;
Margaron, Philippe;
Handa, James T.

Publication type:

Article

Oxidized low density lipoproteins induce a pathologic response by retinal pigmented epithelial cells.

Published in:

Journal of Neurochemistry, 2008, v. 105, n. 4, p. 1187, doi. 10.1111/j.1471-4159.2008.05211.x

By:

Yamada, Yuko;
Tian, Jane;
Yang, Yanqin;
Cutler, Roy G.;
Tinghuai Wu;
Telljohann, Richard S.;
Mattson, Mark P.;
Handa, James T.

Publication type:

Article

Perfluorocarbon temperature measurements using <sup>19</sup>F NMR.

Published in:

NMR in Biomedicine, 1992, v. 5, n. 2, p. 65, doi. 10.1002/nbm.1940050204

By:

Berkowitz, Bruce A.;
Handa, James T.;
Wilson, Charles A.

Publication type:

Article

Cell Death in AMD: The Rationale for Targeting Fas.

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 3, p. 592, doi. 10.3390/jcm11030592

By:

Zacks, David N.;
Kocab, Andrew J.;
Choi, Joanne J.;
Gregory-Ksander, Meredith S.;
Cano, Marisol;
Handa, James T.

Publication type:

Article

Density-dependent expression of FGF-2 in response to oxidative stressin RPE cells in vitro.

Published in:

Current Eye Research, 2001, v. 23, n. 3, p. 226, doi. 10.1076/ceyr.23.3.226.5467

By:

Wada, Mitsumasa;
Gelfman, Claire Mazow;
Matsunaga, Hiroshi;
Alizadeh, Mitra;
Morse, Lawrence;
Handa, James T.;
Hjelmeland, Leonard M.

Publication type:

Article

Clearance of antitransferrin receptor immunotoxin from the rabbit eye.

Published in:

Current Eye Research, 1996, v. 15, n. 10, p. 1039, doi. 10.3109/02713689609017653

By:

Handa, James T.;
Pearson, P. Andrew;
Jaffe, Glenn J.

Publication type:

Article

Monensin enhances the cytotoxic effect of antitransferrin receptor immunotoxin on cultured RPE cells.

Published in:

Current Eye Research, 1993, v. 12, n. 1, p. 45, doi. 10.3109/02713689308999495

By:

Handa, James T.;
Houston, L. L.;
Jaffe, Glenn J.

Publication type:

Article

Clarin‐1 expression in adult mouse and human retina highlights a role of Müller glia in Usher syndrome.

Published in:

Journal of Pathology, 2020, v. 250, n. 2, p. 195, doi. 10.1002/path.5360

By:

Xu, Lei;
Bolch, Susan N;
Santiago, Clayton P;
Dyka, Frank M;
Akil, Omar;
Lobanova, Ekaterina S;
Wang, Yuchen;
Martemyanov, Kirill A;
Hauswirth, William W;
Smith, W Clay;
Handa, James T;
Blackshaw, Seth;
Ash, John D;
Dinculescu, Astra

Publication type:

Article

Pentraxin 3 recruits complement factor H to protect against oxidative stress-induced complement and inflammasome overactivation.

Published in:

Journal of Pathology, 2016, v. 240, n. 4, p. 495, doi. 10.1002/path.4811

By:

Wang, Lei;
Cano, Marisol;
Datta, Sayantan;
Wei, Hong;
Ebrahimi, Katayoon B;
Gorashi, Yara;
Garlanda, Cecilia;
Handa, James T

Publication type:

Article

A review of the literature for intra-arterial chemotherapy used to treat retinoblastoma.

Published in:

2016

By:

Wyse, Emily;
Handa, James;
Friedman, Alan;
Pearl, Monica;
Handa, James T;
Friedman, Alan D;
Pearl, Monica S

Publication type:

journal article

Microglia–Neutrophil Interactions Drive Dry AMD-like Pathology in a Mouse Model.

Published in:

Cells (2073-4409), 2022, v. 11, n. 22, p. 3535, doi. 10.3390/cells11223535

By:

Boyce, Maeve;
Xin, Ying;
Chowdhury, Olivia;
Shang, Peng;
Liu, Haitao;
Koontz, Victoria;
Strizhakova, Anastasia;
Nemani, Mihir;
Hose, Stacey;
Zigler Jr., J. Samuel;
Campbell, Matthew;
Sinha, Debasish;
Handa, James T.;
Kaarniranta, Kai;
Qian, Jiang;
Ghosh, Sayan

Publication type:

Article

A systems biology approach towards understanding and treating non-neovascular age-related macular degeneration.

Published in:

Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11262-1

By:

Handa, James T.;
Farrer, Lindsay A.;
Bowes Rickman, Cathy;
Toth, Cynthia A.;
Dick, Andrew D.;
Gorin, Michael B.;
Miller, Joan W.;
Ueffing, Marius;
Zarbin, Marco

Publication type:

Article

Socioeconomic disadvantage and impact on visual outcomes in patients with viral retinitis and retinal detachment.

Published in:

Journal of Ophthalmic Inflammation & Infection, 2022, v. 12, n. 1, p. 1, doi. 10.1186/s12348-022-00303-4

By:

Zhou, Ashley;
Ong, Sally S.;
Ahmed, Ishrat;
Arevalo, J. Fernando;
Cai, Cindy X.;
Handa, James T.

Publication type:

Article

Concise Review: Using Stem Cells to Prevent the Progression of Myopia-A Concept.

Published in:

Stem Cells, 2015, v. 33, n. 7, p. 2104, doi. 10.1002/stem.1984

By:

Walczak, Piotr;
Janowski, Miroslaw;
Bulte, Jeff W.M.;
Handa, James T.;
Rini, David

Publication type:

Article

Decreased membrane complement regulators in the retinal pigmented epithelium contributes to age-related macular degeneration.

Published in:

Journal of Pathology, 2013, v. 229, n. 5, p. 729, doi. 10.1002/path.4128

By:

Ebrahimi, Katayoon B;
Fijalkowski, Natalia;
Cano, Marisol;
Handa, James T

Publication type:

Article

Complement factor H binds malondialdehyde epitopes and protects from oxidative stress.

Published in:

Nature, 2011, v. 478, n. 7367, p. 76, doi. 10.1038/nature10449

By:

Weismann, David;
Hartvigsen, Karsten;
Lauer, Nadine;
Bennett, Keiryn L.;
Scholl, Hendrik P. N.;
Issa, Peter Charbel;
Cano, Marisol;
Brandstätter, Hubert;
Tsimikas, Sotirios;
Skerka, Christine;
Superti-Furga, Giulio;
Handa, James T.;
Zipfel, Peter F.;
Witztum, Joseph L.;
Binder, Christoph J.

Publication type:

Article

βA1-crystallin regulates glucose metabolism and mitochondrial function in mouse retinal astrocytes by modulating PTP1B activity.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-021-01763-5

By:

Ghosh, Sayan;
Liu, Haitao;
Yazdankhah, Meysam;
Stepicheva, Nadezda;
Shang, Peng;
Vaidya, Tanuja;
Hose, Stacey;
Gupta, Urvi;
Calderon, Michael Joseph;
Hu, Ming-Wen;
Nair, Archana Padmanabhan;
Weiss, Joseph;
Fitting, Christopher S.;
Bhutto, Imran A.;
Gadde, Santosh Gopi Krishna;
Naik, Naveen Kumar;
Jaydev, Chaitra;
Lutty, Gerard A.;
Handa, James T.;
Jayagopal, Ashwath

Publication type:

Article

Combination of apolipoprotein-A-I/apolipoprotein-A-I binding protein and anti-VEGF treatment overcomes anti-VEGF resistance in choroidal neovascularization in mice.

Published in:

Communications Biology, 2020, v. 3, n. 1, p. 1, doi. 10.1038/s42003-020-1113-z

By:

Zhu, Lingping;
Parker, Mackenzie;
Enemchukwu, Nduka;
Shen, Megan;
Zhang, Guogang;
Yan, Qing;
Handa, James T.;
Fang, Longhou;
Fu, Yingbin

Publication type:

Article

Nrf2 deficiency decreases NADPH from impaired IDH shuttle and pentose phosphate pathway in retinal pigmented epithelial cells to magnify oxidative stress‐induced mitochondrial dysfunction.

Published in:

Aging Cell, 2021, v. 20, n. 8, p. 1, doi. 10.1111/acel.13444

By:

Cano, Marisol;
Datta, Sayantan;
Wang, Lei;
Liu, Tongyun;
Flores‐Bellver, Miguel;
Sachdeva, Mira;
Sinha, Debasish;
Handa, James T.

Publication type:

Article

The amino acid transporter SLC36A4 regulates the amino acid pool in retinal pigmented epithelial cells and mediates the mechanistic target of rapamycin, complex 1 signaling.

Published in:

Aging Cell, 2017, v. 16, n. 2, p. 349, doi. 10.1111/acel.12561

By:

Shang, Peng;
Valapala, Mallika;
Grebe, Rhonda;
Hose, Stacey;
Ghosh, Sayan;
Bhutto, Imran A.;
Handa, James T.;
Lutty, Gerard A.;
Lu, Lixia;
Wan, Jun;
Qian, Jiang;
Sergeev, Yuri;
Puertollano, Rosa;
Zigler, J. Samuel;
Xu, Guo‐Tong;
Sinha, Debasish

Publication type:

Article

Increased Lipocalin-2 in the retinal pigment epithelium of Cryba1 c KO mice is associated with a chronic inflammatory response.

Published in:

Aging Cell, 2014, v. 13, n. 6, p. 1091, doi. 10.1111/acel.12274

By:

Valapala, Mallika;
Edwards, Malia;
Hose, Stacey;
Grebe, Rhonda;
Bhutto, Imran A.;
Cano, Marisol;
Berger, Thorsten;
Mak, Tak W.;
Wawrousek, Eric;
Handa, James T.;
Lutty, Gerard A.;
Samuel Zigler, J.;
Sinha, Debasish

Publication type:

Article

Glycation-altered proteolysis as a pathobiologic mechanism that links dietary glycemic index, aging, and age-related disease (in nondiabetics).

Published in:

Aging Cell, 2012, v. 11, n. 1, p. 1, doi. 10.1111/j.1474-9726.2011.00752.x

By:

Uchiki, Tomoaki;
Weikel, Karen A.;
Jiao, Wangwang;
Shang, Fu;
Caceres, Andrea;
Pawlak, Dorota;
Handa, James T.;
Brownlee, Michael;
Nagaraj, Ram;
Taylor, Allen

Publication type:

Article