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RAS nanoclusters are cell surface transducers that convert extracellular stimuli to intracellular signalling.
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- FEBS Letters, 2023, v. 597, n. 6, p. 892, doi. 10.1002/1873-3468.14569
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- Article
Glycolysis regulates KRAS plasma membrane localization and function through defined glycosphingolipids.
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- Nature Communications, 2023, v. 14, n. 1, p. 1, doi. 10.1038/s41467-023-36128-5
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- Article
Lipid Profiles of RAS Nanoclusters Regulate RAS Function.
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- Biomolecules (2218-273X), 2021, v. 11, n. 10, p. 1439, doi. 10.3390/biom11101439
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- Article
Oncogenic KRAS is dependent upon an EFR3A-PI4KA signaling axis for potent tumorigenic activity.
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- Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-25523-5
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- Article
Neratinib degrades MST4 via autophagy that reduces membrane stiffness and is essential for the inactivation of PI3K, ERK1/2, and YAP/TAZ signaling.
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- Journal of Cellular Physiology, 2020, v. 235, n. 11, p. 7889, doi. 10.1002/jcp.29443
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- Article
(Curcumin+sildenafil) enhances the efficacy of 5FU and anti‐PD1 therapies in vivo.
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- Journal of Cellular Physiology, 2020, v. 235, n. 10, p. 6862, doi. 10.1002/jcp.29580
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- Article
RAS Function in cancer cells: translating membrane biology and biochemistry into new therapeutics.
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- Biochemical Journal, 2020, v. 477, n. 15, p. 2893, doi. 10.1042/BCJ20190839
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- Article
Corrigendum: Fingolimod Augments Monomethylfumarate Killing of GBM Cells.
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- 2020
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- Correction Notice
Fingolimod Augments Monomethylfumarate Killing of GBM Cells.
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- Frontiers in Oncology, 2020, v. 10, p. 1, doi. 10.3389/fonc.2020.00022
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- Article
HRAS‐driven cancer cells are vulnerable to TRPML1 inhibition.
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- EMBO Reports, 2019, v. 20, n. 4, p. N.PAG, doi. 10.15252/embr.201846685
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- Article
Neratinib augments the lethality of [regorafenib + sildenafil].
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- Journal of Cellular Physiology, 2019, v. 234, n. 4, p. 4874, doi. 10.1002/jcp.27276
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- Article
Three distinct regions of cRaf kinase domain interact with membrane.
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- Scientific Reports, 2019, v. 9, n. 1, p. 1, doi. 10.1038/s41598-019-38770-w
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- Article
Deciphering lipid codes: K‐Ras as a paradigm.
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- Traffic, 2018, v. 19, n. 3, p. 157, doi. 10.1111/tra.12541
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- Article
Computational and biochemical characterization of two partially overlapping interfaces and multiple weak-affinity K-Ras dimers.
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- Scientific Reports, 2017, p. 40109, doi. 10.1038/srep40109
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- Article
Epac1 interacts with importin β1 and controls neurite outgrowth independently of cAMP and Rap1.
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- Scientific Reports, 2016, p. 36370, doi. 10.1038/srep36370
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- Article
Specific cancer associated mutations in the switch III-region of Ras increase tumorigenicity by nanocluster augmentation.
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- eLife, 2015, p. 1, doi. 10.7554/eLife.08905
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- Article
Binding hotspots on K-ras: Consensus ligand binding sites and other reactive regions from probe-based molecular dynamics analysis.
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- Proteins, 2015, v. 83, n. 5, p. 898, doi. 10.1002/prot.24786
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- Article
Co-Regulation of Cell Polarization and Migration by Caveolar Proteins PTRF/Cavin-1 and Caveolin-1.
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- PLoS ONE, 2012, v. 7, n. 8, p. 1, doi. 10.1371/journal.pone.0043041
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- Article
Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells.
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- Journal of Cell Biology, 2010, v. 190, n. 4, p. 675, doi. 10.1083/jcb.201002119
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- Article
H-Ras Nanocluster Stability Regulates the Magnitude of MAPK Signal Output.
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- PLoS ONE, 2010, v. 5, n. 8, p. 1, doi. 10.1371/journal.pone.0011991
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- Article
Signalling ballet in space and time.
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- Nature Reviews Molecular Cell Biology, 2010, v. 11, n. 6, p. 414, doi. 10.1038/nrm2901
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- Article
The Nonsteroidal Anti-Inflammatory Drug Indomethacin Induces Heterogeneity in Lipid Membranes: Potential Implication for Its Diverse Biological Action.
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- PLoS ONE, 2010, v. 5, n. 1, p. 1, doi. 10.1371/journal.pone.0008811
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- Article
Hydrophobic and Basic Domains Target Proteins to Lipid Droplets.
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- Traffic, 2009, v. 10, n. 12, p. 1785, doi. 10.1111/j.1600-0854.2009.00994.x
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- Article
MURC/Cavin-4 and cavin family members form tissue-specific caveolar complexes.
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- Journal of Cell Biology, 2009, v. 185, n. 7, p. 1259, doi. 10.1083/jcb.200903053
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- Article
An agonist-induced conformational change in the growth hormone receptor determines the choice of signalling pathway.
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- Nature Cell Biology, 2008, v. 10, n. 6, p. 740, doi. 10.1038/ncb1737
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- Article
A novel switch region regulates H-ras membrane orientation and signal output.
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- EMBO Journal, 2008, v. 27, n. 5, p. 727, doi. 10.1038/emboj.2008.10
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- Article
Reassessing the Role of Phosphocaveolin-1 in Cell Adhesion and Migration.
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- Traffic, 2007, v. 8, n. 12, p. 1695, doi. 10.1111/j.1600-0854.2007.00653.x
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- Article
Plasma membrane nanoswitches generate high-fidelity Ras signal transduction.
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- Nature Cell Biology, 2007, v. 9, n. 8, p. 905, doi. 10.1038/ncb1615
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- Article
PA promoted to manager.
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- Nature Cell Biology, 2007, v. 9, n. 6, p. 615, doi. 10.1038/ncb0607-615
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- Article
Cholesterol-Sensitive Cdc42 Activation Regulates Actin Polymerization for Endocytosis via the GEEC Pathway.
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- Traffic, 2007, v. 8, n. 6, p. 702, doi. 10.1111/j.1600-0854.2007.00565.x
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- Article
Lipid rafts and membrane traffic
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- FEBS Letters, 2007, v. 581, n. 11, p. 2098, doi. 10.1016/j.febslet.2007.03.019
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- Article
Lipid rafts: contentious only from simplistic standpoints.
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- Nature Reviews Molecular Cell Biology, 2006, v. 7, n. 6, p. 456, doi. 10.1038/nrm1925
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- Article
Zebrafish as a model for caveolin-associated muscle disease; caveolin-3 is required for myofibril organization and muscle cell patterning.
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- Human Molecular Genetics, 2005, v. 14, n. 13, p. 1727, doi. 10.1093/hmg/ddi179
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- Article
Ultrastructural identification of uncoated caveolin- independent early endocytic vehicles.
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- Journal of Cell Biology, 2005, v. 168, n. 3, p. 465, doi. 10.1083/jcb.200407078
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- Article
Ras proteins: different signals from different locations.
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- Nature Reviews Molecular Cell Biology, 2003, v. 4, n. 5, p. 373, doi. 10.1038/nrm1105
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- Article
Direct visulization of Ras proteins in spatially distinct cell surface microdomains.
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- Journal of Cell Biology, 2003, v. 160, n. 2, p. 165, doi. 10.1083/jcb.200209091
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- Article
Which Ras rides the raft? - Reply.
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- Nature Cell Biology, 2001, v. 3, n. 8, p. E172, doi. 10.1038/35087100
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- Article
Protein phosphatases 1 and 2A promote Raf-1 activation by regulating 14-3-3 interactions.
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- Oncogene, 2001, v. 20, n. 30, p. 3949, doi. 10.1038/sj.onc.1204526
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- Article
GTP-dependent segregation of H-ras from lipid rafts is required for biological activity.
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- Nature Cell Biology, 2001, v. 3, n. 4, p. 368, doi. 10.1038/35070050
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- Article
Interactions of c-Raf-1 with phosphatidylserine and 14-3-3.
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- Oncogene, 1999, v. 18, n. 26, p. 3862, doi. 10.1038/sj.onc.1202730
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- Article
Dominant-negative caveolin inhibits H-Ras function by disrupting cholesterol-rich plasma membrane domains.
- Published in:
- Nature Cell Biology, 1999, v. 1, n. 2, p. 98, doi. 10.1038/10067
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- Article