Works by Hales, Chadwick M.

Results: 25

The Georgia Memory Net: Implementation of a statewide program to diagnose and treat Alzheimer's disease and related dementias.
Published in:
Journal of the American Geriatrics Society, 2022, v. 70, n. 4, p. 1257, doi. 10.1111/jgs.17690
By:
- Bender, Alexis A.;
- McIntosh, Rebecca L.;
- Sudduth, Sean;
- Harris, Michaela;
- Tuckey, Kathy;
- Morgan, John C.;
- Jungerman, Joanna M.;
- Cox, Abby;
- Moore, Miranda A.;
- Ingram, Bryshia;
- Pier, Ellyn;
- Johnson, Theodore M.;
- Loring, David W.;
- Hepburn, Kenneth;
- Medders, Laura;
- Levey, Allan I.;
- Lah, James J.;
- Hales, Chadwick M.
Publication type:
Article
Pharmacologic Inhibition of ROCK2 Suppresses Amyloid-ß Production in an Alzheimer's Disease Mouse Model.
Published in:
Journal of Neuroscience, 2013, v. 33, n. 49, p. 19086, doi. 10.1523/JNEUROSCI.2508-13.2013
By:
- Herskowitz, Jeremy H.;
- Yangbo Feng;
- Mattheyses, Alexa L.;
- Hales, Chadwick M.;
- Higginbotham, Lenora A.;
- Duong, Duc M.;
- Montine, Thomas J.;
- Troncoso, Juan C.;
- Thambisetty, Madhav;
- Seyfried, Nicholas T.;
- Levey, Allan I.;
- Lah, James J.
Publication type:
Article
CRISPR-mediated gene correction links the ATP7A M1311V mutations with amyotrophic lateral sclerosis pathogenesis in one individual.
Published in:
Communications Biology, 2020, v. 3, n. 1, p. 1, doi. 10.1038/s42003-020-0755-1
By:
- Yun, Yeomin;
- Hong, Sung-Ah;
- Kim, Ka-Kyung;
- Baek, Daye;
- Lee, Dongsu;
- Londhe, Ashwini M.;
- Lee, Minhyung;
- Yu, Jihyeon;
- McEachin, Zachary T.;
- Bassell, Gary J.;
- Bowser, Robert;
- Hales, Chadwick M.;
- Cho, Sung-Rae;
- Kim, Janghwan;
- Pae, Ae Nim;
- Cheong, Eunji;
- Kim, Sangwoo;
- Boulis, Nicholas M.;
- Bae, Sangsu;
- Ha, Yoon
Publication type:
Article
Stimulus-evoked high frequency oscillations are present in neuronal networks on microelectrode arrays.
Published in:
Frontiers in Neural Circuits, 2012, p. 1, doi. 10.3389/fncir.2012.00029
By:
- Hales, Chadwick M.;
- Zeller-Townson, Riley;
- Newman, Jonathan P.;
- Shoemaker, James T.;
- Killian, Nathan J.;
- Potter, Steve M.
Publication type:
Article
From frontotemporal lobar degeneration pathology to frontotemporal lobar degeneration biomarkers.
Published in:
International Review of Psychiatry, 2013, v. 25, n. 2, p. 210, doi. 10.3109/09540261.2013.776522
By:
- Hales, Chadwick M.;
- Hu, William T.
Publication type:
Article
Integration of plasma and CSF metabolomics with CSF proteomic reveals novel associations between lipid mediators and central nervous system vascular and energy metabolism.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-39737-8
By:
- Borkowski, Kamil;
- Seyfried, Nicholas T.;
- Arnold, Matthias;
- Lah, James J.;
- Levey, Allan I.;
- Hales, Chadwick M.;
- Dammer, Eric B.;
- Blach, Colette;
- Louie, Gregory;
- Kaddurah-Daouk, Rima;
- Newman, John W.
Publication type:
Article
Integration of plasma and CSF metabolomics with CSF proteomic reveals novel associations between lipid mediators and central nervous system vascular and energy metabolism.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-39737-8
By:
- Borkowski, Kamil;
- Seyfried, Nicholas T.;
- Arnold, Matthias;
- Lah, James J.;
- Levey, Allan I.;
- Hales, Chadwick M.;
- Dammer, Eric B.;
- Blach, Colette;
- Louie, Gregory;
- Kaddurah-Daouk, Rima;
- Newman, John W.
Publication type:
Article
Fibroblast bioenergetics to classify amyotrophic lateral sclerosis patients.
Published in:
Molecular Neurodegeneration, 2017, v. 12, p. 1, doi. 10.1186/s13024-017-0217-5
By:
- Konrad, Csaba;
- Hibiki Kawamata;
- Bredvik, Kirsten G.;
- Arreguin, Andrea J.;
- Cajamarca, Steven A.;
- Hupf, Jonathan C.;
- Ravits, John M.;
- Miller, Timothy M.;
- Maragakis, Nicholas J.;
- Hales, Chadwick M.;
- Glass, Jonathan D.;
- Gross, Steven;
- Hiroshi Mitsumoto;
- Manfredi, Giovanni
Publication type:
Article
Trehalose upregulates progranulin expression in human and mouse models of GRN haploinsufficiency: a novel therapeutic lead to treat frontotemporal dementia.
Published in:
Molecular Neurodegeneration, 2016, v. 11, p. 1, doi. 10.1186/s13024-016-0114-3
By:
- Holler, Christopher J.;
- Taylor, Georgia;
- McEachin, Zachary T.;
- Qiudong Deng;
- Watkins, William J.;
- Hudson, Kathryn;
- Easley, Charles A.;
- Hu, William T.;
- Hales, Chadwick M.;
- Rossoll, Wilfried;
- Bassell, Gary J.;
- Kukar, Thomas
Publication type:
Article
U1 small nuclear ribonucleoproteins (snRNPs) aggregate in Alzheimer's disease due to autosomal dominant genetic mutations and trisomy 21.
Published in:
Molecular Neurodegeneration, 2014, v. 9, n. 1, p. 1, doi. 10.1186/1750-1326-9-15
By:
- Hales, Chadwick M.;
- Seyfried, Nicholas T.;
- Dammer, Eric B.;
- Duc Duong;
- Hong Yi;
- Gearing, Marla;
- Troncoso, Juan C.;
- Mufson, Elliott J.;
- Thambisetty, Madhav;
- Levey, Allan I.;
- Lah, James J.
Publication type:
Article
Aggregates of Small Nuclear Ribonucleic Acids ( snRNAs) in Alzheimer's Disease.
Published in:
Brain Pathology, 2014, v. 24, n. 4, p. 344, doi. 10.1111/bpa.12133
By:
- Hales, Chadwick M.;
- Dammer, Eric B.;
- Diner, Ian;
- Yi, Hong;
- Seyfried, Nicholas T.;
- Gearing, Marla;
- Glass, Jonathan D.;
- Montine, Thomas J.;
- Levey, Allan I.;
- Lah, James J.
Publication type:
Article
Changes in the detergent-insoluble brain proteome linked to amyloid and tau in Alzheimer's Disease progression.
Published in:
Proteomics, 2016, v. 16, n. 23, p. 3042, doi. 10.1002/pmic.201600057
By:
- Hales, Chadwick M.;
- Dammer, Eric B.;
- Deng, Qiudong;
- Duong, Duc M.;
- Gearing, Marla;
- Troncoso, Juan C.;
- Thambisetty, Madhav;
- Lah, James J.;
- Shulman, Joshua M.;
- Levey, Allan I.;
- Seyfried, Nicholas T.
Publication type:
Article
CSF complement 3 and factor H are staging biomarkers in Alzheimer's disease.
Published in:
Acta Neuropathologica Communications, 2016, v. 4, p. 1, doi. 10.1186/s40478-016-0277-8
By:
- Hu, William T.;
- Watts, Kelly D.;
- Tailor, Prashant;
- Nguyen, Trung P.;
- Howell, Jennifer C.;
- Lee, Raven C.;
- Seyfried, Nicholas T.;
- Gearing, Marla;
- Hales, Chadwick M.;
- Levey, Allan I.;
- Lah, James J.;
- Lee, Eva K.
Publication type:
Article
A proteomic network approach resolves stage-specific molecular phenotypes in chronic traumatic encephalopathy.
Published in:
Molecular Neurodegeneration, 2021, v. 16, n. 1, p. 1, doi. 10.1186/s13024-021-00462-3
By:
- Gutierrez-Quiceno, Laura;
- Dammer, Eric B.;
- Johnson, Ashlyn Grace;
- Webster, James A.;
- Shah, Rhythm;
- Duong, Duc;
- Yin, Luming;
- Seyfried, Nicholas T.;
- Alvarez, Victor E.;
- Stein, Thor D.;
- McKee, Ann C.;
- Hales, Chadwick M.
Publication type:
Article
Quantitative proteomics of acutely-isolated mouse microglia identifies novel immune Alzheimer's disease-related proteins.
Published in:
Molecular Neurodegeneration, 2018, v. 13, n. 1, p. N.PAG, doi. 10.1186/s13024-018-0266-4
By:
- Rangaraju, Srikant;
- Dammer, Eric B.;
- Raza, Syed Ali;
- Gao, Tianwen;
- Xiao, Hailian;
- Betarbet, Ranjita;
- Duong, Duc M.;
- Webster, James A.;
- Hales, Chadwick M.;
- Lah, James J.;
- Levey, Allan I.;
- Seyfried, Nicholas T.
Publication type:
Article
A phase II study repurposing atomoxetine for neuroprotection in mild cognitive impairment.
Published in:
2022
By:
- Levey, Allan I;
- Qiu, Deqiang;
- Zhao, Liping;
- Hu, William T;
- Duong, Duc M;
- Higginbotham, Lenora;
- Dammer, Eric B;
- Seyfried, Nicholas T;
- Wingo, Thomas S;
- Hales, Chadwick M;
- Tansey, Malú Gámez;
- Goldstein, David S;
- Abrol, Anees;
- Calhoun, Vince D;
- Goldstein, Felicia C;
- Hajjar, Ihab;
- Fagan, Anne M;
- Galasko, Doug;
- Edland, Steven D;
- Hanfelt, John
Publication type:
journal article
Lower Prevalence of Asymptomatic Alzheimer's Disease Among Healthy African Americans.
Published in:
Annals of Neurology, 2024, v. 96, n. 3, p. 463, doi. 10.1002/ana.26960
By:
- Lah, James J.;
- Tian, Ganzhong;
- Risk, Benjamin B.;
- Hanfelt, John J.;
- Wang, Liangkang;
- Zhao, Liping;
- Hales, Chadwick M.;
- Johnson, Erik C.B.;
- Elmor, Morgan B.;
- Malakauskas, Sarah J.;
- Heilman, Craig;
- Wingo, Thomas S.;
- Dorbin, Cornelya D.;
- Davis, Crystal P.;
- Thomas, Tiffany I.;
- Hajjar, Ihab M.;
- Levey, Allan I.;
- Parker, Monica W.
Publication type:
Article
Literature-Based Discovery Predicts Antihistamines Are a Promising Repurposed Adjuvant Therapy for Parkinson's Disease.
Published in:
International Journal of Molecular Sciences, 2023, v. 24, n. 15, p. 12339, doi. 10.3390/ijms241512339
By:
- Tandra, Gabriella;
- Yoone, Amy;
- Mathew, Rhea;
- Wang, Minzhi;
- Hales, Chadwick M.;
- Mitchell, Cassie S.
Publication type:
Article
Dynamics of the Apical Plasma Membrane Recycling System During Cell Division.
Published in:
Traffic, 2003, v. 4, n. 10, p. 681, doi. 10.1034/j.1600-0854.2003.00124.x
By:
- Hobdy-Henderson, Karen C.;
- Hales, Chadwick M.;
- Lapierre, Lynne A.;
- Cheney, Richard E.;
- Goldenring, James R.
Publication type:
Article
Fat mass and obesity-associated (FTO) protein interacts with CaMKII and modulates the activity of CREB signaling pathway.
Published in:
Human Molecular Genetics, 2014, v. 23, n. 12, p. 3299, doi. 10.1093/hmg/ddu043
By:
- Lin, Li;
- Hales, Chadwick M.;
- Garber, Kathryn;
- Jin, Peng
Publication type:
Article
Urokinase-type plasminogen activator promotes N-cadherin-mediated synaptic recovery in the ischemic brain.
Published in:
Journal of Cerebral Blood Flow & Metabolism, 2021, v. 41, n. 9, p. 2381, doi. 10.1177/0271678X211002297
By:
- Diaz, Ariel;
- Merino, Paola;
- McCann, Patrick;
- Yepes, Manuel A;
- Quiceno, Laura G;
- Torre, Enrique;
- Tomkins, Amelia;
- Zhang, Xiaodong;
- Hales, Chadwick M;
- Tong, Frank C;
- Yepes, Manuel
Publication type:
Article
APOE loss‐of‐function variants: Compatible with longevity and associated with resistance to Alzheimer's Disease pathology.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2023, v. 19, p. 1, doi. 10.1002/alz.082628
By:
- Guen, Yann Le;
- Chemparathy, Augustine;
- Chen, Sunny;
- Leong, Lesley;
- Gorzynski, John John;
- Xue, Guangxue;
- Belloy, Michael E;
- Kasireddy, Nandita;
- Tauber, Andres Peña;
- Williams, Kennedy;
- Wingo, Thomas S.;
- Lah, James J.;
- Jayadev, Suman;
- Hales, Chadwick M;
- Peskind, Elaine R;
- Child, Daniel D;
- Keene, C Dirk;
- Le, Cong;
- Ashley, Euan;
- Yu, Chang‐En
Publication type:
Article
O4‐11‐05: A PROOF OF CONCEPT PHASE II STUDY REPURPOSING ATOMOXETINE FOR NEUROPROTECTION IN MILD COGNITIVE IMPAIRMENT: EVIDENCE FOR TARGET ENGAGEMENT, REGULATION OF CSF BIOMARKERS, AND DISEASE‐MODIFYING POTENTIAL.
Published in:
Alzheimer's & Dementia: The Journal of the Alzheimer's Association, 2019, v. 15, p. P1263, doi. 10.1016/j.jalz.2019.06.4804
By:
- Levey, Allan I.;
- Lah, James J.;
- Hu, William T.;
- Wingo, Thomas S.;
- Hales, Chadwick M.;
- Manzanares, Cecelia;
- Tansey, Malu G.;
- Goldstein, David S.;
- Zhao, Liping;
- Galasko, Douglas R.;
- Edland, Steven D.;
- Hanfelt, John;
- Weinshenker, David
Publication type:
Article
Proteomic networks of gray and white matter reveal tissue‐specific changes in human tauopathy.
Published in:
Annals of Clinical & Translational Neurology, 2024, v. 11, n. 8, p. 2138, doi. 10.1002/acn3.52134
By:
- Johnson, Ashlyn G.;
- Dammer, Eric B.;
- Webster, James A.;
- Duong, Duc M.;
- Seyfried, Nicholas T.;
- Hales, Chadwick M.
Publication type:
Article
Association of plasma and CSF cytochrome P450, soluble epoxide hydrolase, and ethanolamide metabolism with Alzheimer's disease.
Published in:
Alzheimer's Research & Therapy, 2021, v. 13, n. 1, p. 1, doi. 10.1186/s13195-021-00893-6
By:
- Borkowski, Kamil;
- Pedersen, Theresa L.;
- Seyfried, Nicholas T.;
- Lah, James J.;
- Levey, Allan I.;
- Hales, Chadwick M.;
- Dammer, Eric B.;
- Blach, Colette;
- Louie, Gregory;
- Kaddurah-Daouk, Rima;
- Newman, John W.
Publication type:
Article