Works matching AU Hales, Barbara F

Results: 56

Paternal cyclophosphamide treatment of rats causes fetal loss and malformations without affecting male fertility.

Published in:

Nature, 1985, v. 316, n. 6024, p. 144, doi. 10.1038/316144a0

By:

Trasler, Jacquetta M.;
Hales, Barbara F.;
Robaire, Bernard

Publication type:

Article

Impact of Exposure to a Mixture of Organophosphate Esters on Adrenal Cell Phenotype, Lipidome, and Function.

Published in:

Endocrinology, 2024, v. 165, n. 4, p. 1, doi. 10.1210/endocr/bqae024

By:

Li, Zixuan;
Hales, Barbara F;
Robaire, Bernard

Publication type:

Article

The Organophosphate Esters Used as Flame Retardants and Plasticizers Affect H295R Adrenal Cell Phenotypes and Functions.

Published in:

Endocrinology, 2023, v. 164, n. 9, p. 1, doi. 10.1210/endocr/bqad119

By:

Li, Zixuan;
Robaire, Bernard;
Hales, Barbara F

Publication type:

Article

Organophosphate Esters Disrupt Steroidogenesis in KGN Human Ovarian Granulosa Cells.

Published in:

Endocrinology, 2023, v. 164, n. 7, p. 1, doi. 10.1210/endocr/bqad089

By:

Wang, Xiaotong;
Lee, Elaine;
Hales, Barbara F;
Robaire, Bernard

Publication type:

Article

Polybrominated Diphenyl Ethers in Human Follicular Fluid Dysregulate Mural and Cumulus Granulosa Cell Gene Expression.

Published in:

Endocrinology, 2021, v. 162, n. 3, p. 1, doi. 10.1210/endocr/bqab003

By:

Lefèvre, Pavine L C;
Nardelli, Thomas C;
Son, Weon-Young;
Sadler, Amy R;
Rawn, Dorothea F K;
Goodyer, Cindy;
Robaire, Bernard;
Hales, Barbara F

Publication type:

Article

Exposure to polystyrene nanoplastics induces lysosomal enlargement and lipid droplet accumulation in KGN human ovarian granulosa cells.

Published in:

Archives of Toxicology, 2025, v. 99, n. 4, p. 1445, doi. 10.1007/s00204-025-03969-6

By:

Zhang, Yunbo;
Hales, Barbara F.;
Robaire, Bernard

Publication type:

Article

Effects of brominated and organophosphate ester flame retardants on male reproduction.

Published in:

Andrology, 2020, v. 8, n. 4, p. 915, doi. 10.1111/andr.12789

By:

Hales, Barbara F.;
Robaire, Bernard

Publication type:

Article

A CASE STUDY OF CANADIAN REGULATION OF BPA: INSIGHT INTO THE SCIENCE.

Published in:

Duke Environmental Law & Policy Forum, 2022, v. 32, n. 2, p. 295

By:

ELLIS, JAYE;
PAPALUCA, ARTURO;
HAMTIAUX, MYRIAM;
HALES, BARBARA F.;
ROBAIRE, BERNARD

Publication type:

Article

Toxicants and human sperm chromatin integrity.

Published in:

Molecular Human Reproduction, 2010, v. 16, n. 1/2, p. 14, doi. 10.1093/molehr/gap087

By:

Delbès, Geraldine;
Hales, Barbara F.;
Robaire, Bernard

Publication type:

Article

Effect on Pregnancy Outcome of Suppression of Spermatogenesis by Testosterone <sup>a</sup>.

Published in:

Annals of the New York Academy of Sciences, 1984, v. 438, n. 1, p. 546, doi. 10.1111/j.1749-6632.1984.tb38331.x

By:

ROBAIRE, BERNARD;
SMITH, SUSAN;
HALES, BARBARA F.

Publication type:

Article

Gestational and Lactational Exposure to an Environmentally-Relevant Mixture of Brominated Flame Retardants: Effects on Neurodevelopment and Metabolism.

Published in:

Birth Defects Research, 2017, v. 109, n. 7, p. 497, doi. 10.1002/bdr2.1021

By:

Tung, Emily W. Y.;
Kawata, Alice;
Rigden, Marc;
Bowers, Wayne J.;
Caldwell, Don;
Holloway, Alison C.;
Robaire, Bernard;
Hales, Barbara F.;
Wade, Michael G.

Publication type:

Article

Assessment of the developmental toxicity of nanoparticles in an ex vivo 3D model, the murine limb bud culture system.

Published in:

Nanotoxicology, 2015, v. 9, n. 6, p. 780, doi. 10.3109/17435390.2014.976850

By:

Bigaeva, Emilia;
Paradis, France-Hélène;
Moquin, Alexandre;
Hales, Barbara F.;
Maysinger, Dusica

Publication type:

Article

The development of adverse outcome pathways for mutagenic effects for the organization for economic co-operation and development.

Published in:

Environmental & Molecular Mutagenesis, 2013, v. 54, n. 2, p. 79, doi. 10.1002/em.21757

By:

Yauk, Carole L.;
Bishop, Jack;
Dearfield, Kerry L.;
Douglas, George R.;
Hales, Barbara F.;
Luijten, Mirjam;
O'Brien, Jason M.;
Robaire, Bernard;
Sram, Radim;
van Benthem, Jan;
Wade, Mike G.;
White, Paul A.;
Marchetti, Francesco

Publication type:

Article

Thalidomide on the comeback trail.

Published in:

Nature Medicine, 1999, v. 5, n. 5, p. 489, doi. 10.1038/8371

By:

Hales, Barbara F.

Publication type:

Article

Effects of Bisphenols A, AF, and S on Endochondral Ossification and the Transcriptome of Murine Limb Buds.

Published in:

Toxicological Sciences, 2022, v. 187, n. 2, p. 234, doi. 10.1093/toxsci/kfab145

By:

Iskandarani, Lama;
McHattie, Tessa;
Robaire, Bernard;
Hales, Barbara F

Publication type:

Article

Effects of Organophosphate Esters Used as Flame Retardants and Plasticizers on Granulosa, Leydig, and Spermatogonial Cells Analyzed Using High-Content Imaging.

Published in:

Toxicological Sciences, 2022, v. 186, n. 2, p. 269, doi. 10.1093/toxsci/kfac012

By:

Wang, Xiaotong;
Luu, Trang;
Beal, Marc A;
Barton-Maclaren, Tara S;
Robaire, Bernard;
Hales, Barbara F

Publication type:

Article

Erratum to: Effects of Bisphenols A, AF, and S on Endochondral Ossification and the Transcriptome of Murine Limb Buds.

Published in:

Toxicological Sciences, 2022, v. 186, n. 1, p. 163, doi. 10.1093/toxsci/kfac001

By:

Iskandarani, Lama;
McHattie, Tessa;
Robaire, Bernard;
Hales, Barbara F

Publication type:

Article

Elucidation of the Effects of Bisphenol A and Structural Analogs on Germ and Steroidogenic Cells Using Single Cell High-Content Imaging.

Published in:

Toxicological Sciences, 2021, v. 180, n. 2, p. 224, doi. 10.1093/toxsci/kfab012

By:

Rajkumar, Abishankari;
Luu, Trang;
Beal, Marc A;
Barton-Maclaren, Tara S;
Robaire, Bernard;
Hales, Barbara F

Publication type:

Article

Effects of an Environmentally Relevant Mixture of Organophosphate Esters Derived From House Dust on Endochondral Ossification in Murine Limb Bud Cultures.

Published in:

Toxicological Sciences, 2021, v. 180, n. 1, p. 62, doi. 10.1093/toxsci/kfaa180

By:

Yan, Han;
Hales, Barbara F

Publication type:

Article

Exposure to tert-Butylphenyl Diphenyl Phosphate, an Organophosphate Ester Flame Retardant and Plasticizer, Alters Hedgehog Signaling in Murine Limb Bud Cultures.

Published in:

Toxicological Sciences, 2020, v. 178, n. 2, p. 251, doi. 10.1093/toxsci/kfaa145

By:

Yan, Han;
Hales, Barbara F

Publication type:

Article

In Utero and Lactational Exposure to Flame Retardants Disrupts Rat Ovarian Follicular Development and Advances Puberty.

Published in:

Toxicological Sciences, 2020, v. 175, n. 2, p. 197, doi. 10.1093/toxsci/kfaa044

By:

Allais, Adélaïde;
Albert, Océane;
Lefèvre, Pavine L C;
Wade, Michael G;
Hales, Barbara F;
Robaire, Bernard

Publication type:

Article

Gestational and Lactational Exposure to an Environmentally Relevant Mixture of Brominated Flame Retardants Downregulates Junctional Proteins, Thyroid Hormone Receptor α1 Expression, and the Proliferation-Apoptosis Balance in Mammary Glands Post Puberty

Published in:

Toxicological Sciences, 2019, v. 171, n. 1, p. 13, doi. 10.1093/toxsci/kfz147

By:

Gouesse, Rita-Josiane;
Lavoie, Mélanie;
Dianati, Elham;
Wade, Mike G;
Hales, Barbara F;
Robaire, Bernard;
Plante, Isabelle

Publication type:

Article

Effects of Organophosphate Ester Flame Retardants on Endochondral Ossification in Ex Vivo Murine Limb Bud Cultures.

Published in:

Toxicological Sciences, 2019, v. 168, n. 2, p. 420, doi. 10.1093/toxsci/kfy301

By:

Yan, Han;
Hales, Barbara F

Publication type:

Article

Response to Letter From Rainer Otter Regarding Albert O. et al. (2017). Identifying Greener and Safer Plasticizers: A Four-Step Approach.

Published in:

2018

By:

Albert, Océane;
Nardelli, Thomas C;
Hales, Barbara F;
Robaire, Bernard

Publication type:

Letter to the Editor

Effects of In Utero and Lactational Exposure to New Generation Green Plasticizers on Adult Male Rats: A Comparative Study With Di(2-Ethylhexyl) Phthalate.

Published in:

Toxicological Sciences, 2018, v. 164, n. 1, p. 129, doi. 10.1093/toxsci/kfy072

By:

Albert, Océane;
Nardelli, Thomas C;
Lalancette, Claudia;
Hales, Barbara F;
Robaire, Bernard

Publication type:

Article

The Roles of P53 and Its Family Proteins, P63 and P73, in the DNA Damage Stress Response in Organogenesis-Stage Mouse Embryos.

Published in:

Toxicological Sciences, 2018, v. 162, n. 2, p. 439, doi. 10.1093/toxsci/kfx270

By:

Husseini, Nazem El;
Hales, Barbara F

Publication type:

Article

Identifying Greener and Safer Plasticizers: A 4-Step Approach.

Published in:

Toxicological Sciences, 2018, v. 161, n. 2, p. 266, doi. 10.1093/toxsci/kfx156

By:

Albert, Océane;
Nardelli, Thomas C;
Hales, Barbara F;
Robaire, Bernard

Publication type:

Article

Exposure to an Environmentally Relevant Mixture of Brominated Flame Retardants Decreased p-β-Catenin<sup>ser675</sup> Expression and Its Interaction With E-Cadherin in the Mammary Glands of Lactating Rats.

Published in:

Toxicological Sciences, 2017, v. 159, n. 1, p. 114, doi. 10.1093/toxsci/kfx123

By:

Dianati, Elham;
Wade, Michael G.;
Hales, Barbara F.;
Robaire, Bernard;
Plante, Isabelle

Publication type:

Article

Hydroxyurea Exposure Activates the P53 Signaling Pathway in Murine Organogenesis-Stage Embryos.

Published in:

Toxicological Sciences, 2016, v. 152, n. 2, p. 297, doi. 10.1093/toxsci/kfw089

By:

Husseini, Nazem El;
Schlisser, Ava E.;
Hales, Barbara F.

Publication type:

Article

Organophosphate Flame Retardants Act as Endocrine-Disrupting Chemicals in MA-10 Mouse Tumor Leydig Cells.

Published in:

Toxicological Sciences, 2016, v. 150, n. 2, p. 499, doi. 10.1093/toxsci/kfw012

By:

Schang, Gauthier;
Robaire, Bernard;
Hales, Barbara F.

Publication type:

Article

The Effects of Class-Specific Histone Deacetylase Inhibitors on the Development of Limbs During Organogenesis.

Published in:

Toxicological Sciences, 2015, v. 148, n. 1, p. 220, doi. 10.1093/toxsci/kfv174

By:

Paradis, France-Hélène;
Hales, Barbara F.

Publication type:

Article

Deprenyl Enhances the Teratogenicity of Hydroxyurea in Organogenesis Stage Mouse Embryos.

Published in:

Toxicological Sciences, 2013, v. 134, n. 2, p. 391, doi. 10.1093/toxsci/kft115

By:

Schlisser, Ava E.;
Hales, Barbara F.

Publication type:

Article

Hydroxyurea Exposure Triggers Tissue-Specific Activation of p38 Mitogen-Activated Protein Kinase Signaling and the DNA Damage Response in Organogenesis-Stage Mouse Embryos.

Published in:

Toxicological Sciences, 2013, v. 133, n. 2, p. 298, doi. 10.1093/toxsci/kft069

By:

Banh, Serena;
Hales, Barbara F.

Publication type:

Article

Exposure to Valproic Acid Inhibits Chondrogenesis and Osteogenesis in Mid-Organogenesis Mouse Limbs.

Published in:

Toxicological Sciences, 2013, v. 131, n. 1, p. 234, doi. 10.1093/toxsci/kfs292

By:

Paradis, France-Hélène;
Hales, Barbara F.

Publication type:

Article

Effects of Chronic Exposure to an Environmentally Relevant Mixture of Brominated Flame Retardants on the Reproductive and Thyroid System in Adult Male Rats.

Published in:

Toxicological Sciences, 2012, v. 127, n. 2, p. 496, doi. 10.1093/toxsci/kfs098

By:

Ernest, Sheila R.;
Wade, Michael G.;
Lalancette, Claudia;
Ma, Yi-Qian;
Berger, Robert G.;
Robaire, Bernard;
Hales, Barbara F.

Publication type:

Article

The Activation of DNA Damage Detection and Repair Responses in Cleavage-Stage Rat Embryos by a Damaged Paternal Genome.

Published in:

Toxicological Sciences, 2012, v. 127, n. 2, p. 555, doi. 10.1093/toxsci/kfs120

By:

Grenier, Lisanne;
Robaire, Bernard;
Hales, Barbara F.

Publication type:

Article

Teratogen-Induced Oxidative Stress Targets Glyceraldehyde-3-Phosphate Dehydrogenase in the Organogenesis Stage Mouse Embryo.

Published in:

Toxicological Sciences, 2010, v. 118, n. 2, p. 686, doi. 10.1093/toxsci/kfq287

By:

Schlisser, Ava E.;
Yan, Jin;
Hales, Barbara F.

Publication type:

Article

Retinoic Acid Receptor Gamma-Induced Misregulation of Chondrogenesis in the Murine Limb Bud In Vitro.

Published in:

Toxicological Sciences, 2008, v. 106, n. 1, p. 223, doi. 10.1093/toxsci/kfn169

By:

Eugene Galdones;
Barbara F. Hales

Publication type:

Article

DNA Damage Recognition in the Rat Zygote Following Chronic Paternal Cyclophosphamide Exposure.

Published in:

Toxicological Sciences, 2007, v. 100, n. 2, p. 495, doi. 10.1093/toxsci/kfm242

By:

Barton, Tara S.;
Robaire, Bernard;
Hales, Barbara F.

Publication type:

Article

Novel Retinoid Targets in the Mouse Limb during Organogenesis.

Published in:

Toxicological Sciences, 2006, v. 94, n. 1, p. 139, doi. 10.1093/toxsci/kfl037

By:

Ali-Khan, Sarah E.;
Hales, Barbara F.

Publication type:

Article

Retinoid Receptor Antagonists Alter the Pattern of Apoptosis in Organogenesis Stage Mouse Limbs.

Published in:

Toxicological Sciences, 2006, v. 90, n. 1, p. 208, doi. 10.1093/toxsci/kfj060

By:

Hales, Barbara F.

Publication type:

Article

Activator Protein-1 (AP-1) DNA Binding Activity Is Induced by Hydroxyurea in Organogenesis Stage Mouse Embryos.

Published in:

Toxicological Sciences, 2005, v. 85, n. 2, p. 1013, doi. 10.1093/toxsci/kfi148

By:

Jin Yan;
Hales, Barbara F

Publication type:

Article

Genotoxic Stress Response Gene Expression in the Mid-Organogenesis Rat Conceptus.

Published in:

Toxicological Sciences, 2003, v. 74, n. 1, p. 157, doi. 10.1093/toxsci/kfg097

By:

Vinson, Robert K.;
Hales, Barbara F.

Publication type:

Article

A Case-Control Study of Maternal Polybrominated Diphenyl Ether (PBDE) Exposure and Cryptorchidism in Canadian Populations.

Published in:

Environmental Health Perspectives, 2017, v. 125, n. 5, p. 1, doi. 10.1289/EHP522

By:

Goodyer, Cynthia G.;
Poon, Shirley;
Aleksa, Katarina;
Hou, Laura;
Atehortua, Veronica;
Carnevale, Amanda;
Jednak, Roman;
Emil, Sherif;
Bagli, Darius;
Dave, Sumit;
Hales, Barbara F.;
Chevrier, Jonathan

Publication type:

Article

Impact of exposure to a mixture of organophosphate esters on the adrenal glands of Sprague Dawley rats.

Published in:

Toxicological Sciences, 2025, v. 204, n. 1, p. 43, doi. 10.1093/toxsci/kfae154

By:

Li, Zixuan;
Hales, Barbara F;
Robaire, Bernard

Publication type:

Article

House dust-derived mixtures of organophosphate esters alter the phenotype, function, transcriptome, and lipidome of KGN human ovarian granulosa cells.

Published in:

Toxicological Sciences, 2024, v. 200, n. 1, p. 95, doi. 10.1093/toxsci/kfae052

By:

Wang, Xiaotong;
Rowan-Carroll, Andrea;
Meier, Matthew J;
Yauk, Carole L;
Wade, Michael G;
Robaire, Bernard;
Hales, Barbara F

Publication type:

Article

Organophosphate ester flame retardants and plasticizers affect the phenotype and function of HepG2 liver cells.

Published in:

Toxicological Sciences, 2024, v. 199, n. 2, p. 261, doi. 10.1093/toxsci/kfae034

By:

Yu, Dongwei;
Hales, Barbara F;
Robaire, Bernard

Publication type:

Article

Toxicological mechanisms and potencies of organophosphate esters in KGN human ovarian granulosa cells as revealed by high-throughput transcriptomics.

Published in:

Toxicological Sciences, 2024, v. 197, n. 2, p. 170, doi. 10.1093/toxsci/kfad114

By:

Wang, Xiaotong;
Rowan-Carroll, Andrea;
Meier, Matthew J;
Williams, Andrew;
Yauk, Carole L;
Hales, Barbara F;
Robaire, Bernard

Publication type:

Article

Polybrominated diphenyl ether (PBDE) neurotoxicity: a systematic review and meta-analysis of animal evidence.

Published in:

Journal of Toxicology & Environmental Health: Part B, 2018, v. 21, n. 4, p. 269, doi. 10.1080/10937404.2018.1514829

By:

Dorman, David C.;
Chiu, Weihsueh;
Hales, Barbara F.;
Hauser, Russ;
Johnson, Kamin J.;
Mantus, Ellen;
Martel, Susan;
Robinson, Karen A.;
Rooney, Andrew A.;
Rudel, Ruthann;
Sathyanarayana, Sheela;
Schantz, Susan L.;
Waters, Katrina M.

Publication type:

Article

Systematic reviews and meta-analyses of human and animal evidence of prenatal diethylhexyl phthalate exposure and changes in male anogenital distance.

Published in:

Journal of Toxicology & Environmental Health: Part B, 2018, v. 21, n. 4, p. 207, doi. 10.1080/10937404.2018.1505354

By:

Dorman, David C.;
Chiu, Weihsueh;
Hales, Barbara F.;
Hauser, Russ;
Johnson, Kamin J.;
Mantus, Ellen;
Martel, Susan;
Robinson, Karen A.;
Rooney, Andrew A.;
Rudel, Ruthann;
Sathyanarayana, Sheela;
Schantz, Susan L.;
Waters, Katrina M.

Publication type:

Article