Works matching AU Halbrook, Christopher J.

Results: 8

Arginase 1 is a key driver of immune suppression in pancreatic cancer.

Published in:

eLife, 2023, p. 1, doi. 10.7554/eLife.80721

By:

Menjivar, Rosa E.;
Nwosu, Zeribe C.;
Wenting Du;
Donahue, Katelyn L.;
Hong, Hanna S.;
Espinoza, Carlos;
Brown, Kristee;
Velez-Delgado, Ashley;
Wei Yan;
Lima, Fatima;
Bischoff, Allison;
Kadiyala, Padma;
Salas-Escabillas, Daniel;
Crawford, Howard C.;
Bednar, Filip;
Carpenter, Eileen;
Yaqing Zhang;
Halbrook, Christopher J.;
Lyssiotis, Costas A.;
di Magliano, Marina Pasca

Publication type:

Article

GOT1 inhibition promotes pancreatic cancer cell death by ferroptosis.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-24859-2

By:

Kremer, Daniel M.;
Nelson, Barbara S.;
Lin, Lin;
Yarosz, Emily L.;
Halbrook, Christopher J.;
Kerk, Samuel A.;
Sajjakulnukit, Peter;
Myers, Amy;
Thurston, Galloway;
Hou, Sean W.;
Carpenter, Eileen S.;
Andren, Anthony C.;
Nwosu, Zeribe C.;
Cusmano, Nicholas;
Wisner, Stephanie;
Mbah, Nneka E.;
Shan, Mengrou;
Das, Nupur K.;
Magnuson, Brian;
Little, Andrew C.

Publication type:

Article

Hyaluronic acid fuels pancreatic cancer cell growth.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.62645

By:

Kim, Peter K.;
Halbrook, Christopher J.;
Kerk, Samuel A.;
Radyk, Megan;
Wisner, Stephanie;
Kremer, Daniel M.;
Sajjakulnukit, Peter;
Andren, Anthony;
Hou, Sean W.;
Trivedi, Ayush;
Thurston, Galloway;
Anand, Abhinav;
Liang Yan;
Salamanca-Cardona, Lucia;
Welling, Samuel D.;
Li Zhang;
Pratt, Matthew R.;
Keshari, Kayvan R.;
Haoqiang Ying;
Lyssiotis, Costas A.

Publication type:

Article

Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy.

Published in:

Cancer & Metabolism, 2020, v. 8, n. 1, p. 1, doi. 10.1186/s40170-019-0202-2

By:

Nelson, Barbara S.;
Lin, Lin;
Kremer, Daniel M.;
Sousa, Cristovão M.;
Cotta-Ramusino, Cecilia;
Myers, Amy;
Ramos, Johanna;
Gao, Tina;
Kovalenko, Ilya;
Wilder-Romans, Kari;
Dresser, Joseph;
Davis, Mary;
Lee, Ho-Joon;
Nwosu, Zeribe C.;
Campit, Scott;
Mashadova, Oksana;
Nicolay, Brandon N.;
Tolstyka, Zachary P.;
Halbrook, Christopher J.;
Chandrasekaran, Sriram

Publication type:

Article

Malic enzyme 1 knockout has no deleterious phenotype and is favored in the male germline under standard laboratory conditions.

Published in:

PLoS ONE, 2024, v. 19, n. 6, p. 1, doi. 10.1371/journal.pone.0303577

By:

Alektiar, Jonathan M.;
Shan, Mengrou;
Radyk, Megan D.;
Zhang, Li;
Halbrook, Christopher J.;
Lin, Lin;
Espinoza, Carlos;
Mier, Ivan F.;
Lavoie, Brooke L.;
Salvatore, Lucie;
Pasca di Magliano, Marina;
Cantley, Lewis C.;
Mueller, Jacob L.;
Lyssiotis, Costas A.

Publication type:

Article

Multiomic characterization of pancreatic cancer-associated macrophage polarization reveals deregulated metabolic programs driven by the GM-CSF-PI3K pathway.

Published in:

eLife, 2022, p. 1, doi. 10.7554/eLife.73796

By:

Boyer, Seth;
Ho-Joon Lee;
Steele, Nina;
Li Zhang;
Sajjakulnukit, Peter;
Andren, Anthony;
Ward, Matthew H.;
Singh, Rima;
Basrur, Venkatesha;
Yaqing Zhang;
Nesvizhskii, Alexey I.;
di Magliano, Marina Pasca;
Halbrook, Christopher J.;
Lyssiotis, Costas A.

Publication type:

Article

Purine metabolism regulates DNA repair and therapy resistance in glioblastoma.

Published in:

Nature Communications, 2020, v. 11, n. 1, p. 1, doi. 10.1038/s41467-020-17512-x

By:

Zhou, Weihua;
Yao, Yangyang;
Scott, Andrew J.;
Wilder-Romans, Kari;
Dresser, Joseph J.;
Werner, Christian K.;
Sun, Hanshi;
Pratt, Drew;
Sajjakulnukit, Peter;
Zhao, Shuang G.;
Davis, Mary;
Nelson, Barbara S.;
Halbrook, Christopher J.;
Zhang, Li;
Gatto, Francesco;
Umemura, Yoshie;
Walker, Angela K.;
Kachman, Maureen;
Sarkaria, Jann N.;
Xiong, Jianping

Publication type:

Article

Menin regulates the serine biosynthetic pathway in Ewing sarcoma.

Published in:

Journal of Pathology, 2018, v. 245, n. 3, p. 324, doi. 10.1002/path.5085

By:

Svoboda, Laurie K.;
Teh, Selina Shiqing K.;
Sud, Sudha;
Kerk, Samuel;
Zebolsky, Aaron;
Treichel, Sydney;
Thomas, Dafydd;
Halbrook, Christopher J.;
Lee, Ho‐Joon;
Kremer, Daniel;
Zhang, Li;
Klossowski, Szymon;
Bankhead, Armand R.;
Magnuson, Brian;
Ljungman, Mats;
Cierpicki, Tomasz;
Grembecka, Jolanta;
Lyssiotis, Costas A.;
Lawlor, Elizabeth R.

Publication type:

Article