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Effect of Hepatic Impairment on the Pharmacokinetics of Nirmatrelvir/Ritonavir, the First Oral Protease Inhibitor for the Treatment of COVID‐19.
Published in:
Journal of Clinical Pharmacology, 2024, v. 64, n. 2, p. 145, doi. 10.1002/jcph.2353
By:
- Singh, Ravi Shankar P.;
- LaBadie, Robert R.;
- Toussi, Sima S.;
- Shi, Haihong;
- Berg, Jolene Kay;
- Neutel, Joel M.;
- Aggarwal, Sudeepta
Publication type:
Article
Population Pharmacokinetics of Talazoparib in Patients With Advanced Cancer.
Published in:
Journal of Clinical Pharmacology, 2020, v. 60, n. 2, p. 218, doi. 10.1002/jcph.1520
By:
- Yu, Yanke;
- Durairaj, Chandrasekar;
- Shi, Haihong;
- Wang, Diane D.
Publication type:
Article
A Phase 1 Mass Balance Study of <sup>14</sup>C‐Labeled Talazoparib in Patients With Advanced Solid Tumors.
Published in:
Journal of Clinical Pharmacology, 2019, v. 59, n. 9, p. 1195, doi. 10.1002/jcph.1415
By:
- Yu, Yanke;
- Chung, Chin‐Hee;
- Plotka, Anna;
- Quinn, Kevin;
- Shi, Haihong;
- Pápai, Zsuzsanna;
- Nguyen, Linh;
- Wang, Diane
Publication type:
Article
Novel Application of the Two‐Period Microtracer Approach to Determine Absolute Oral Bioavailability and Fraction Absorbed of Ertugliflozin.
Published in:
CTS: Clinical & Translational Science, 2018, v. 11, n. 4, p. 405, doi. 10.1111/cts.12549
By:
- Raje, Sangeeta;
- Callegari, Ernesto;
- Sahasrabudhe, Vaishali;
- Vaz, Alfin;
- Shi, Haihong;
- Fluhler, Eric;
- Woolf, Eric J.;
- Schildknegt, Klaas;
- Matschke, Kyle;
- Alvey, Christine;
- Zhou, Susan;
- Papadopoulos, Dimitris;
- Fountaine, Robert;
- Saur, Didier;
- Terra, Steven G.;
- Stevens, Lloyd;
- Gaunt, Daniel;
- Cutler, David L.
Publication type:
Article
The use of chemical derivatization to enhance liquid chromatography/tandem mass spectrometric determination of 1-hydroxypyrene, a biomarker for polycyclic aromatic hydrocarbons in human urine.
Published in:
Rapid Communications in Mass Spectrometry: RCM, 2005, v. 19, n. 22, p. 3331, doi. 10.1002/rcm.2196
By:
- Li, Yinghe;
- Li, Austin C.;
- Shi, Haihong;
- Zhou, Shaolian;
- Shou, Wilson Z.;
- Jiang, Xiangyu;
- Naidong, Weng;
- Lauterbach, John H.
Publication type:
Article
Development, validation and transfer of a hydrophilic interaction liquid chromatography/tandem mass spectrometric method for the analysis of the tobacco-specific nitrosamine metabolite NNAL in human plasma at low picogram per milliliter concentrations.
Published in:
Rapid Communications in Mass Spectrometry: RCM, 2004, v. 18, n. 21, p. 2549, doi. 10.1002/rcm.1656
By:
- Pan, Jiongwei;
- Song, Qi;
- Shi, Haihong;
- King, Melissa;
- Junga, Heiko;
- Zhou, Shaolian;
- Naidong, Weng
Publication type:
Article
Dosing recommendation of nirmatrelvir/ritonavir using an integrated population pharmacokinetic analysis.
Published in:
CPT: Pharmacometrics & Systems Pharmacology, 2023, v. 12, n. 12, p. 1897, doi. 10.1002/psp4.13039
By:
- Chan, Phylinda L. S.;
- Singh, Ravi Shankar P.;
- Cox, Donna S.;
- Shi, Haihong;
- Damle, Bharat;
- Nicholas, Timothy
Publication type:
Article
A Comprehensive Review of the Clinical Pharmacokinetics, Pharmacodynamics, and Drug Interactions of Nirmatrelvir/Ritonavir.
Published in:
Clinical Pharmacokinetics, 2024, v. 63, n. 1, p. 27, doi. 10.1007/s40262-023-01339-y
By:
- Gerhart, Jacqueline;
- Cox, Donna S.;
- Singh, Ravi Shankar P.;
- Chan, Phylinda L. S.;
- Rao, Rohit;
- Allen, Richard;
- Shi, Haihong;
- Masters, Joanna C.;
- Damle, Bharat
Publication type:
Article
The Effect of Renal Impairment on the Pharmacokinetics and Safety of Talazoparib in Patients with Advanced Solid Tumors.
Published in:
Clinical Pharmacokinetics, 2021, v. 60, n. 7, p. 921, doi. 10.1007/s40262-020-00983-y
By:
- Durairaj, Chandrasekar;
- Chakrabarti, Jayeta;
- Ferrario, Cristiano;
- Hirte, Holger W.;
- Babu, Sunil;
- Piha-Paul, Sarina A.;
- Plotka, Anna;
- Hoffman, Justin;
- Shi, Haihong;
- Wang, Diane D.
Publication type:
Article
Association of eNOS Polymorphisms with Anterior Chamber Depth in Han Chinese: Jiangsu Eye Study.
Published in:
2014
By:
- Haihong Shi;
- Rongrong Zhu;
- Nan Hu;
- Jian Shi;
- Junfang Zhang;
- Mei Yang;
- Linjuan Jiang;
- Hong Jiang;
- Huaijin Guan
Publication type:
Journal Article
Association of eNOS Polymorphisms with Anterior Chamber Depth in Han Chinese: Jiangsu Eye Study.
Published in:
Journal of Ophthalmology, 2014, p. 1, doi. 10.1155/2014/164104
By:
- Haihong Shi;
- Rongrong Zhu;
- Nan Hu;
- Jian Shi;
- Junfang Zhang;
- Mei Yang;
- Linjuan Jiang;
- Hong Jiang;
- Huaijin Guan
Publication type:
Article
An Extensive Replication Study on Three New Susceptibility Loci of Primary Angle Closure Glaucoma in Han Chinese: Jiangsu Eye Study.
Published in:
Journal of Ophthalmology, 2013, p. 1, doi. 10.1155/2013/641596
By:
- Haihong Shi;
- Rongrong Zhu;
- Nan Hu;
- Jian Shi;
- Junfang Zhang;
- Linjuan Jiang;
- Hong Jiang;
- Huaijin Guan
Publication type:
Article
Patient Centric Microsampling to Support Paxlovid Clinical Development: Bridging and Implementation.
Published in:
Clinical Pharmacology & Therapeutics, 2024, v. 115, n. 1, p. 42, doi. 10.1002/cpt.3025
By:
- Wan, Katty;
- Kavetska, Olga;
- Damle, Bharat;
- Shi, Haihong;
- Cox, Donna S.;
- Oladoyinbo, Olayide;
- Chan, Phylinda;
- Singh, Ravi Shankar P.;
- Craft, Susan;
- Berthier, Erwin;
- Corrigan, Brian
Publication type:
Article
Extra-Thyroid Extension Prediction by Ultrasound Quantitative Method Based on Thyroid Capsule Response Evaluation.
Published in:
Medical Science Monitor, 2021, v. 27, p. 1, doi. 10.12659/MSM.929408
By:
- Minghang Lin;
- Yiming Su;
- Weili Wei;
- Yiran Gong;
- Yinan Huang;
- Jinshu Zeng;
- Liya Li;
- Haihong Shi;
- Shuqiang Chen
Publication type:
Article
Tumor‑suppressive effects of Smad‑ubiquitination regulator 2 in papillary thyroid carcinoma.
Published in:
Oncology Letters, 2024, v. 27, n. 6, p. N.PAG, doi. 10.3892/ol.2024.14396
By:
- Luo, Guirong;
- Zhang, Liting;
- Zhang, Lihong;
- Wu, Wenyi;
- Lin, Jianqing;
- Shi, Haihong;
- Yu, Yihuang;
- Qiu, Weigang;
- Chen, Jinyan;
- Ding, Hansen;
- Chen, Xinyao
Publication type:
Article
Upregulation of ubiquitin carboxy‑terminal hydrolase 47 (USP47) in papillary thyroid carcinoma ex vivo and reduction of tumor cell malignant behaviors after USP47 knockdown by stabilizing SATB1 expression in vitro.
Published in:
Oncology Letters, 2023, v. 26, n. 3, p. N.PAG, doi. 10.3892/ol.2023.13956
By:
- Luo, Guirong;
- Zhang, Liting;
- Wu, Wenyi;
- Zhang, Lihong;
- Lin, Jianqing;
- Shi, Haihong;
- Wu, Xinquan;
- Yu, Yihuang;
- Qiu, Weigang;
- Chen, Jinyan;
- Ding, Hansen;
- Chen, Xinyao
Publication type:
Article
ASF1B: A Possible Prognostic Marker, Therapeutic Target, and Predictor of Immunotherapy in Male Thyroid Carcinoma.
Published in:
Frontiers in Oncology, 2022, v. 12, p. 1, doi. 10.3389/fonc.2022.678025
By:
- Qiu, Weigang;
- Wu, Xinquan;
- Shi, Haihong;
- Liu, Bingyang;
- Li, Liqiong;
- Wu, Wenyi;
- Lin, Jianqing
Publication type:
Article
Pharmacokinetics of Oral Nirmatrelvir/Ritonavir, a Protease Inhibitor for Treatment of COVID‐19, in Subjects With Renal Impairment.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 4, p. 892, doi. 10.1002/cpt.2688
By:
- Toussi, Sima S.;
- Neutel, Joel Michael;
- Navarro, Jesus;
- Preston, Richard Alfred;
- Shi, Haihong;
- Kavetska, Olga;
- LaBadie, Robert R.;
- Binks, Michael;
- Chan, Phylinda L.S.;
- Demers, Neil;
- Corrigan, Brian;
- Damle, Bharat
Publication type:
Article
Innovative Randomized Phase I Study and Dosing Regimen Selection to Accelerate and Inform Pivotal COVID‐19 Trial of Nirmatrelvir.
Published in:
Clinical Pharmacology & Therapeutics, 2022, v. 112, n. 1, p. 101, doi. 10.1002/cpt.2603
By:
- Singh, Ravi Shankar P.;
- Toussi, Sima S.;
- Hackman, Frances;
- Chan, Phylinda L.;
- Rao, Rohit;
- Allen, Richard;
- Van Eyck, Lien;
- Pawlak, Sylvester;
- Kadar, Eugene P.;
- Clark, Frances;
- Shi, Haihong;
- Anderson, Annaliesa S.;
- Binks, Michael;
- Menon, Sandeep;
- Nucci, Gianluca;
- Bergman, Arthur
Publication type:
Article
Palbociclib (PD-0332991) pharmacokinetics in subjects with impaired renal function.
Published in:
Cancer Chemotherapy & Pharmacology, 2020, v. 86, n. 6, p. 701, doi. 10.1007/s00280-020-04163-4
By:
- Yu, Yanke;
- Hoffman, Justin;
- Plotka, Anna;
- O'Gorman, Melissa;
- Shi, Haihong;
- Wang, Diane
Publication type:
Article
Primary Angle Closure and Sequence Variants within MicroRNA Binding Sites of Genes Involved in Eye Development.
Published in:
PLoS ONE, 2016, v. 11, n. 11, p. 1, doi. 10.1371/journal.pone.0166055
By:
- Shi, Haihong;
- Zhang, Junfang;
- Zhu, Rongrong;
- Hu, Nan;
- Lu, Hong;
- Yang, Mei;
- Qin, Bai;
- Shi, Jian;
- Guan, Huaijin
Publication type:
Article
High Expression of Serine Hydroxymethyltransferase 2 Indicates Poor Prognosis of Gastric Cancer Patients.
Published in:
Medical Science Monitor, 2019, v. 25, p. 7430, doi. 10.12659/MSM.917435
By:
- Haihong Shi;
- Xiaoxu Fang;
- Yanfang Li;
- Yingchun Zhang
Publication type:
Article
Presence of free triiodothyronine and free thyroxine in thyroid follicles may be correlated with the quick secretion of thyroid hormones under certain physiological conditions.
Published in:
Biomedical Reports, 2016, v. 4, n. 4, p. 467, doi. 10.3892/br.2016.596
By:
- HAIHONG SHI;
- WANRONG LIN;
- BO LIANG;
- HUIYAO CAI;
- QINGYAN CAI;
- YAXIONG SHI;
- HUIBIN HUANG
Publication type:
Article
Effects of itraconazole and carbamazepine on the pharmacokinetics of nirmatrelvir/ritonavir in healthy adults.
Published in:
British Journal of Clinical Pharmacology, 2023, v. 89, n. 9, p. 2867, doi. 10.1111/bcp.15788
By:
- Cox, Donna S.;
- Van Eyck, Lien;
- Pawlak, Sylvester;
- Beckerman, Bruce;
- Linn, Carlos;
- Ginman, Katherine;
- Thay Cha, Youliny;
- LaBadie, Robert R.;
- Shi, Haihong;
- Damle, Bharat
Publication type:
Article
Safety, Tolerability, and Pharmacokinetics of Intravenous Doses of PF‐07304814, a Phosphate Prodrug Protease Inhibitor for the Treatment of SARS‐CoV‐2, in Healthy Adult Participants.
Published in:
Clinical Pharmacology in Drug Development, 2022, v. 11, n. 12, p. 1382, doi. 10.1002/cpdd.1174
By:
- Zhu, Tong;
- Pawlak, Sylvester;
- Toussi, Sima S.;
- Hackman, Frances;
- Thompson, Kimberly;
- Song, Wei;
- Salageanu, Joanne;
- Winter, Erica;
- Shi, Haihong;
- Winton, Jennifer;
- Binks, Michael
Publication type:
Article
Bioequivalence of Metformin in Ertugliflozin/Metformin Fixed‐Dose Combination Tablets to Canadian‐Sourced Metformin Coadministered With Ertugliflozin Under Fasted and Fed States.
Published in:
Clinical Pharmacology in Drug Development, 2021, v. 10, n. 5, p. 510, doi. 10.1002/cpdd.884
By:
- Dawra, Vikas Kumar;
- Pelletier, Kathleen;
- Matschke, Kyle;
- Shi, Haihong;
- Hickman, Anne;
- Zhou, Susan;
- Krishna, Rajesh;
- Sahasrabudhe, Vaishali
Publication type:
Article
Bioequivalence of Ertugliflozin/Metformin Fixed‐Dose Combination Tablets and Coadministration of Respective Strengths of Individual Components.
Published in:
Clinical Pharmacology in Drug Development, 2020, v. 9, n. 1, p. 50, doi. 10.1002/cpdd.703
By:
- Dawra, Vikas Kumar;
- Liang, Yali;
- Wei, Hua;
- Pelletier, Kathleen;
- Shi, Haihong;
- Hickman, Anne;
- Bass, Almasa;
- Terra, Steven G.;
- Zhou, Susan;
- Krishna, Rajesh;
- Sahasrabudhe, Vaishali
Publication type:
Article
Pharmacokinetic Properties of Single and Multiple Doses of Ertugliflozin, a Selective Inhibitor of SGLT2, in Healthy Chinese Subjects.
Published in:
Clinical Pharmacology in Drug Development, 2020, v. 9, n. 1, p. 97, doi. 10.1002/cpdd.686
By:
- Li, Yinhua;
- Mu, Yuting;
- Shi, Haihong;
- Liang, Yali;
- Liu, Zeyuan;
- Matschke, Kyle;
- Hickman, Anne;
- Krishna, Rajesh;
- Sahasrabudhe, Vaishali
Publication type:
Article
Bioequivalence of Ertugliflozin/Sitagliptin Fixed‐Dose Combination Tablets and Coadministration of Respective Strengths of Individual Components.
Published in:
Clinical Pharmacology in Drug Development, 2019, v. 8, n. 7, p. 884, doi. 10.1002/cpdd.722
By:
- Fediuk, Daryl J.;
- Matschke, Kyle;
- Liang, Yali;
- Pelletier, Kathleen B.;
- Wei, Hua;
- Shi, Haihong;
- Bass, Almasa;
- Hickman, Anne;
- Terra, Steven G.;
- Zhou, Susan;
- Krishna, Rajesh;
- Sahasrabudhe, Vaishali
Publication type:
Article
Effect of Food on the Pharmacokinetics of Ertugliflozin and Its Fixed‐Dose Combinations Ertugliflozin/Sitagliptin and Ertugliflozin/Metformin.
Published in:
Clinical Pharmacology in Drug Development, 2019, v. 8, n. 5, p. 619, doi. 10.1002/cpdd.629
By:
- Sahasrabudhe, Vaishali;
- Fediuk, Daryl J.;
- Matschke, Kyle;
- Shi, Haihong;
- Liang, Yali;
- Hickman, Anne;
- Bass, Almasa;
- Terra, Steven G.;
- Zhou, Susan;
- Krishna, Rajesh;
- Dawra, Vikas K.
Publication type:
Article
Assessment of the Drug Interaction Potential of Ertugliflozin With Sitagliptin, Metformin, Glimepiride, or Simvastatin in Healthy Subjects.
Published in:
Clinical Pharmacology in Drug Development, 2019, v. 8, n. 3, p. 314, doi. 10.1002/cpdd.472
By:
- Dawra, Vikas Kumar;
- Cutler, David L.;
- Zhou, Susan;
- Krishna, Rajesh;
- Shi, Haihong;
- Liang, Yali;
- Alvey, Christine;
- Hickman, Anne;
- Saur, Didier;
- Terra, Steven G.;
- Sahasrabudhe, Vaishali
Publication type:
Article
A Phase 1, Randomized, Placebo‐ and Active‐Controlled Crossover Study to Determine the Effect of Single‐Dose Ertugliflozin on QTc Interval in Healthy Volunteers.
Published in:
Clinical Pharmacology in Drug Development, 2018, v. 7, n. 5, p. 513, doi. 10.1002/cpdd.421
By:
- Sahasrabudhe, Vaishali;
- Saur, Didier;
- Matschke, Kyle;
- Terra, Steven G.;
- Hickman, Anne;
- Huyghe, Isabelle;
- Shi, Haihong;
- Cutler, David L.
Publication type:
Article
Evaluation of the Effect of Tofacitinib on the Pharmacokinetics of Oral Contraceptive Steroids in Healthy Female Volunteers.
Published in:
Clinical Pharmacology in Drug Development, 2016, v. 5, n. 5, p. 336, doi. 10.1002/cpdd.270
By:
- Menon, Sujatha;
- Riese, Richard;
- Wang, Ronnie;
- Alvey, Christine W.;
- Shi, Haihong;
- Petit, Wendy;
- Krishnaswami, Sriram
Publication type:
Article
Single- and multiple-dose pharmacokinetics of tofacitinib in healthy Chinese volunteers.
Published in:
Clinical Pharmacology in Drug Development, 2015, v. 4, n. 5, p. 395, doi. 10.1002/cpdd.202
By:
- Krishnaswami, Sriram;
- Wang, Tao;
- Yuan, Yi;
- Alvey, Christine W.;
- Checchio, Tina;
- Peterson, Mark;
- Shi, Haihong;
- Riese, Richard
Publication type:
Article
Evaluation of the potential interaction between tofacitinib and drugs that undergo renal tubular secretion using metformin, an in vivo marker of renal organic cation transporter 2.
Published in:
Clinical Pharmacology in Drug Development, 2014, v. 3, n. 6, p. 499, doi. 10.1002/cpdd.120
By:
- Klamerus, Karen J.;
- Alvey, Christine;
- Li, Lei;
- Feng, Bo;
- Wang, Rong;
- Kaplan, Irina;
- Shi, Haihong;
- Dowty, Martin E.;
- Krishnaswami, Sriram
Publication type:
Article
DNA Damage in Lens Epithelial Cells and Peripheral Lymphocytes from Age-Related Cataract Patients.
Published in:
Ophthalmic Research, 2014, v. 51, n. 3, p. 124, doi. 10.1159/000356399
By:
- Zhang, Junfang;
- Wu, Jian;
- Yang, Ling;
- Zhu, Rongrong;
- Yang, Mei;
- Qin, Bai;
- Shi, Haihong;
- Guan, Huaijin
Publication type:
Article
Evaluation of pharmacokinetics and safety of talazoparib in patients with advanced cancer and varying degrees of hepatic impairment.
Published in:
British Journal of Clinical Pharmacology, 2022, v. 88, n. 7, p. 3392, doi. 10.1111/bcp.15294
By:
- Guo, Cen;
- Yu, Yanke;
- Chakrabarti, Jayeta;
- Piha‐Paul, Sarina A.;
- Moroose, Rebecca;
- Plotka, Anna;
- Shi, Haihong;
- Durairaj, Chandrasekar;
- Wang, Diane D.;
- Wainberg, Zev A.
Publication type:
Article
Evaluation of the effect of P‐glycoprotein inhibition and induction on talazoparib disposition in patients with advanced solid tumours.
Published in:
British Journal of Clinical Pharmacology, 2020, v. 86, n. 4, p. 771, doi. 10.1111/bcp.14178
By:
- Elmeliegy, Mohamed;
- Láng, István;
- Smolyarchuk, Elena A.;
- Chung, Chin‐Hee;
- Plotka, Anna;
- Shi, Haihong;
- Wang, Diane
Publication type:
Article
Determination of S-phenylmercapturic acid in human urine using an automated sample extraction and fast liquid chromatography-tandem mass spectrometric method.
Published in:
Biomedical Chromatography, 2006, v. 20, n. 6/7, p. 597, doi. 10.1002/bmc.653
By:
- Li, Yinghe;
- Li, Austin C.;
- Shi, Haihong;
- Junga, Heiko;
- Jiang, Xiangyu;
- Naidong, Weng;
- Lauterbach, John H.
Publication type:
Article
Current Research Progress on Long Noncoding RNAs Associated with Hepatocellular Carcinoma.
Published in:
Analytical Cellular Pathology: Cellular Oncology, 2019, p. 1, doi. 10.1155/2019/1534607
By:
- Shi, Haihong;
- Xu, Yuxin;
- Yi, Xin;
- Fang, Dandan;
- Hou, Xia
Publication type:
Article
Inhibition of YAP ameliorates choroidal neovascularization via inhibiting endothelial cell proliferation.
Published in:
Molecular Vision, 2018, v. 24, p. 83
By:
- Zhenzhen Yan;
- Haihong Shi;
- Rongrong Zhu;
- Lele Li;
- Bai Qin;
- Lihua Kang;
- Hui Chen;
- Huaijin Guan
Publication type:
Article

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