Works by Hai-Hui Xue

Results: 31

Bystander responses impact accurate detection of murine and human antigen-specific CD8 T cells.

Published in:

2019

By:

Martin, Matthew D.;
Jensen, Isaac J.;
Ishizuka, Andrew S.;
Lefebvre, Mitchell;
Qiang Shan;
Hai-Hui Xue;
Harty, John T.;
Seder, Robert A.;
Badovinac, Vladimir P.;
Shan, Qiang;
Xue, Hai-Hui

Publication type:

journal article

Sepsis leads to lasting changes in phenotype and function of memory CD8 T cells.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.70989

By:

Jensen, Isaac J.;
Xiang Li;
McGonagill, Patrick W.;
Qiang Shan;
Fosdick, Micaela G.;
Tremblay, Mikaela M.;
Houtman, Jon C. D.;
Hai-Hui Xue;
Griffith, Thomas S.;
Weiqun Peng;
Badovinac, Vladimir P.

Publication type:

Article

Protective function and durability of mouse lymph node-resident memory CD8+ T cells.

Published in:

eLife, 2021, p. 1, doi. 10.7554/eLife.68662

By:

Anthony, Scott M.;
Van Braeckel-Budimir, Natalija;
Moioffer, Steven J.;
de Wall, Stephanie van;
Qiang Shan;
Vijay, Rahul;
Sompallae, Ramakrishna;
Hartwig, Stacey M.;
Jensen, Isaac J.;
Varga, Steven M.;
Butler, Noah S.;
Hai-Hui Xue;
Badovinac, Vladimir P.;
Harty, John T.

Publication type:

Article

Oncogenic and Tumor Suppressor Functions for Lymphoid Enhancer Factor 1 in E2a-/- T Acute Lymphoblastic Leukemia.

Published in:

Frontiers in Immunology, 2022, v. 13, p. 1, doi. 10.3389/fimmu.2022.845488

By:

Carr, Tiffany;
McGregor, Stephanie;
Dias, Sheila;
Verykokakis, Mihalis;
Le Beau, Michelle M.;
Xue, Hai-Hui;
Sigvardsson, Mikael;
Bartom, Elizabeth T.;
Kee, Barbara L.

Publication type:

Article

Stage-specific epigenetic regulation of CD4 expression by coordinated enhancer elements during T cell development.

Published in:

Nature Communications, 2018, p. 1, doi. 10.1038/s41467-018-05834-w

By:

Issuree, Priya D.;
Day, Kenneth;
Au, Christy;
Ramya Raviram;
Zappile, Paul;
Skok, Jane A.;
Hai-Hui Xue;
Myers, Richard M.;
Littman, Dan R.

Publication type:

Article

GA-binding protein regulates KIS gene expression, cell migration, and cell cycle progression.

Published in:

FASEB Journal, 2008, v. 22, n. 1, p. 225, doi. 10.1096/fj.07-8573com

By:

Crook, Martin F.;
Olive, Michelle;
Hai-Hui Xue;
Langenickel, Thomas H.;
Boehm, Manfred;
Leonard, Warren J.;
Nabel, Elizabeth G.

Publication type:

Article

β-Catenin is required for the differentiation of iNKT2 and iNKT17 cells that augment IL-25-dependent lung inflammation.

Published in:

BMC Immunology, 2015, v. 16, p. 1, doi. 10.1186/s12865-015-0121-0

By:

Berga-Bolaños, Rosa;
Sharma, Archna;
Steinke, Farrah C.;
Pyaram, Kalyani;
Yeung-Hyen Kim;
Sultana, Dil A.;
Fang, Jessie X.;
Cheong-Hee Chang;
Hai-Hui Xue;
Heller, Nicola M.;
Sen, Jyoti Misra

Publication type:

Article

Phenotypic and Functional Alterations in Circulating Memory CD8 T Cells with Time after Primary Infection.

Published in:

PLoS Pathogens, 2015, v. 11, n. 10, p. 1, doi. 10.1371/journal.ppat.1005219

By:

Martin, Matthew D.;
Kim, Marie T.;
Shan, Qiang;
Sompallae, Ramakrishna;
Xue, Hai-Hui;
Harty, John T.;
Badovinac, Vladimir P.

Publication type:

Article

The Timing of Stimulation and IL-2 Signaling Regulate Secondary CD8 T Cell Responses.

Published in:

PLoS Pathogens, 2015, v. 11, n. 10, p. 1, doi. 10.1371/journal.ppat.1005199

By:

Khan, Shaniya H.;
Martin, Matthew D.;
Starbeck-Miller, Gabriel R.;
Xue, Hai-Hui;
Harty, John T.;
Badovinac, Vladimir P.

Publication type:

Article

Fidelity of a BAC-EGFP transgene in reporting dynamic expression of IL-7Rα in T cells.

Published in:

Transgenic Research, 2012, v. 21, n. 1, p. 201, doi. 10.1007/s11248-011-9508-8

By:

Yu, Shuyang;
Zhou, Xinyuan;
Hsiao, Jordy;
Yu, Dahai;
Saunders, Thomas;
Xue, Hai-Hui

Publication type:

Article

Ezh2 programs TFH differentiation by integrating phosphorylation-dependent activation of Bcl6 and polycomb-dependent repression of p19Arf.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-07853-z

By:

Li, Fengyin;
Zeng, Zhouhao;
Xing, Shaojun;
Gullicksrud, Jodi A.;
Shan, Qiang;
Choi, Jinyong;
Badovinac, Vladimir P.;
Crotty, Shane;
Peng, Weiqun;
Xue, Hai-Hui

Publication type:

Article

Polymicrobial sepsis influences NK-cell-mediated immunity by diminishing NK-cell-intrinsic receptor-mediated effector responses to viral ligands or infections.

Published in:

PLoS Pathogens, 2018, v. 14, n. 10, p. 1, doi. 10.1371/journal.ppat.1007405

By:

Jensen, Isaac J.;
Winborn, Christina S.;
Fosdick, Micaela G.;
Shao, Peng;
Tremblay, Mikaela M.;
Shan, Qiang;
Tripathy, Sandeep Kumar;
Snyder, Christopher M.;
Xue, Hai-Hui;
Griffith, Thomas S.;
Houtman, Jon C.;
Badovinac, Vladimir P.

Publication type:

Article

Store Depletion by Caffeine/Ryanodine Activates Capacitative Ca2+ Entry in Nonexcitable A549 Cells1.

Published in:

Journal of Biochemistry, 2000, v. 128, n. 2, p. 329, doi. 10.1093/oxfordjournals.jbchem.a022757

By:

Xue, Hai-Hui;
Zhao, Dong-Mei;
Suda, Takafumi;
Uchida, Chiharu;
Oda, Toshiaki;
Chida, Kingo;
Ichiyama, Arata;
Nakamnrat, Hirotoshi

Publication type:

Article

Regulation of mature T cell responses by the Wnt signaling pathway.

Published in:

Annals of the New York Academy of Sciences, 2012, v. 1247, n. 1, p. 16, doi. 10.1111/j.1749-6632.2011.06302.x

By:

Xue, Hai‐Hui;
Zhao, Dong‐Mei

Publication type:

Article

Time and Antigen-Stimulation History Influence Memory CD8 T Cell Bystander Responses.

Published in:

Frontiers in Immunology, 2017, p. 1, doi. 10.3389/fimmu.2017.00634

By:

Martin, Matthew D.;
Shan, Qiang;
Hai-Hui Xue;
Badovinac, Vladimir P.

Publication type:

Article

Serine phosphorylation of Stat5 proteins in lymphocytes stimulated with IL‐2.

Published in:

International Immunology, 2002, v. 14, n. 11, p. 1263, doi. 10.1093/intimm/dxf101

By:

Xue, Hai‐Hui;
Fink, Donald W.;
Zhang, Xiaolong;
Qin, Jun;
Turck, Christoph W.;
Leonard, Warren J.

Publication type:

Article

Little to no expression of angiotensin‐converting enzyme‐2 on most human peripheral blood immune cells but highly expressed on tissue macrophages.

Published in:

Cytometry. Part A, 2023, v. 103, n. 2, p. 136, doi. 10.1002/cyto.a.24285

By:

Song, Xiang;
Hu, Wei;
Yu, Haibo;
Zhao, Laura;
Zhao, Yeqian;
Zhao, Xin;
Xue, Hai‐Hui;
Zhao, Yong

Publication type:

Article

From inception to output, Tcf1 and Lef1 safeguard development of T cells and innate immune cells.

Published in:

Immunologic Research, 2014, v. 59, n. 1-3, p. 45, doi. 10.1007/s12026-014-8545-9

By:

Steinke, Farrah;
Xue, Hai-Hui

Publication type:

Article

Lef1-dependent hypothalamic neurogenesis inhibits anxiety.

Published in:

PLoS Biology, 2017, v. 15, n. 8, p. 1, doi. 10.1371/journal.pbio.2002257

By:

Xie, Yuanyuan;
Kaufmann, Dan;
Moulton, Matthew J.;
Panahi, Samin;
Gaynes, John A.;
Watters, Harrison N.;
Zhou, Dingxi;
Xue, Hai-Hui;
Fung, Camille M.;
Levine, Edward M.;
Letsou, Anthea;
Brennan, K. C.;
Dorsky, Richard I.

Publication type:

Article

Critical roles of mTOR Complex 1 and 2 for T follicular helper cell differentiation and germinal center responses.

Published in:

eLife, 2016, p. 1, doi. 10.7554/eLife.17936

By:

Jialong Yang;
Xingguang Lin;
Yun Pan;
Jinli Wang;
Pengcheng Chen;
Hongxiang Huang;
Hai-Hui Xue;
Jimin Gao;
Xiao-Ping Zhong

Publication type:

Article

HSF1 is a driver of leukemia stem cell self-renewal in acute myeloid leukemia.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33861-1

By:

Dong, Qianze;
Xiu, Yan;
Wang, Yang;
Hodgson, Christina;
Borcherding, Nick;
Jordan, Craig;
Buchanan, Jane;
Taylor, Eric;
Wagner, Brett;
Leidinger, Mariah;
Holman, Carol;
Thiele, Dennis J.;
O'Brien, Sean;
Xue, Hai-hui;
Zhao, Jinming;
Li, Qingchang;
Meyerson, Howard;
Boyce, Brendan F.;
Zhao, Chen

Publication type:

Article

Polymicrobial sepsis impairs bystander recruitment of effector cells to infected skin despite optimal sensing and alarming function of skin resident memory CD8 T cells.

Published in:

PLoS Pathogens, 2017, v. 13, n. 9, p. 1, doi. 10.1371/journal.ppat.1006569

By:

Danahy, Derek B.;
Anthony, Scott M.;
Jensen, Isaac J.;
Hartwig, Stacey M.;
Shan, Qiang;
Xue, Hai-Hui;
Harty, John T.;
Griffith, Thomas S.;
Badovinac, Vladimir P.

Publication type:

Article

Targeting the GA Binding Protein β1L Isoform Does Not Perturb Lymphocyte Development and Function.

Published in:

Molecular & Cellular Biology, 2008, v. 28, n. 13, p. 8

By:

Hai-Hui Xue;
Xuefang Jing;
Bollenbacher-Reilley, Julie;
Dong-Mei Zhao;
Haring, Jodie S.;
Baoli Yang;
Chengyu Liu;
Bishop, Gail A.;
Harty, John T.;
Leonard, Warren J.

Publication type:

Article

Interleukin-21 Receptor Gene Induction in Human T Cells Is Mediated by T-Cell Receptor-Induced Sp1 Activity.

Published in:

Molecular & Cellular Biology, 2005, v. 25, n. 22, p. 9741, doi. 10.1128/MCB.25.22.9741-9752.2005

By:

Zheng Wu;
Hyoung-Pyo Kim;
Hai-Hui Xue;
Hong Liu;
Keji Zhao;
Leonard, Warren J.

Publication type:

Article

TCF-1 upregulation identifies early innate lymphoid progenitors in the bone marrow.

Published in:

Nature Immunology, 2015, v. 16, n. 10, p. 1044, doi. 10.1038/ni.3248

By:

Yang, Qi;
Li, Fengyin;
Harly, Christelle;
Xing, Shaojun;
Ye, Longyun;
Xia, Xuefeng;
Wang, Haikun;
Wang, Xinxin;
Yu, Shuyang;
Zhou, Xinyuan;
Cam, Maggie;
Xue, Hai-Hui;
Bhandoola, Avinash

Publication type:

Article

LEF-1 and TCF-1 orchestrate TFH differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6.

Published in:

Nature Immunology, 2015, v. 16, n. 9, p. 980, doi. 10.1038/ni.3226

By:

Choi, Youn Soo;
Gullicksrud, Jodi A;
Xing, Shaojun;
Zeng, Zhouhao;
Shan, Qiang;
Li, Fengyin;
Love, Paul E;
Peng, Weiqun;
Xue, Hai-Hui;
Crotty, Shane

Publication type:

Article

TCF-1 and LEF-1 act upstream of Th-POK to promote the CD4+ T cell fate and interact with Runx3 to silence Cd4 in CD8+ T cells.

Published in:

Nature Immunology, 2014, v. 15, n. 7, p. 646, doi. 10.1038/ni.2897

By:

Steinke, Farrah C;
Yu, Shuyang;
Zhou, Xinyuan;
He, Bing;
Yang, Wenjing;
Zhou, Bo;
Kawamoto, Hiroshi;
Zhu, Jun;
Tan, Kai;
Xue, Hai-Hui

Publication type:

Article

GA binding protein regulates interleukin 7 receptora-chain gene expression in T cells.

Published in:

Nature Immunology, 2004, v. 5, n. 10, p. 1036, doi. 10.1038/ni1117

By:

Hai-Hui Xue;
Bollenbacher, Julie;
Rovella, Valentina;
Tripuraneni, Radhika;
Yu-Bin Du;
Cheng-Yu Liu;
Williams, Ann;
McCoy, J. Philip;
Leonard, Warren J.

Publication type:

Article

Targeting Cbx3 /HP1γ Induces LEF-1 and IL-21R to Promote Tumor-Infiltrating CD8 T-Cell Persistence.

Published in:

Frontiers in Immunology, 2021, v. 12, p. 1, doi. 10.3389/fimmu.2021.738958

By:

Le, Phuong T.;
Ha, Ngoc;
Tran, Ngan K.;
Newman, Andrew G.;
Esselen, Katharine M.;
Dalrymple, John L.;
Schmelz, Eva M.;
Bhandoola, Avinash;
Xue, Hai-Hui;
Singh, Prim B.;
Thai, To-Ha

Publication type:

Article

Tcf1 and Lef1 provide constant supervision to mature CD8+ T cell identity and function by organizing genomic architecture.

Published in:

Nature Communications, 2021, v. 12, n. 1, p. 1, doi. 10.1038/s41467-021-26159-1

By:

Shan, Qiang;
Li, Xiang;
Chen, Xia;
Zeng, Zhouhao;
Zhu, Shaoqi;
Gai, Kexin;
Peng, Weiqun;
Xue, Hai-Hui

Publication type:

Article

Lrp5 and Lrp6 are required for maintaining self-renewal and differentiation of hematopoietic stem cells.

Published in:

FASEB Journal, 2019, v. 33, n. 4, p. 5615, doi. 10.1096/fj.201802072R

By:

Juanjuan Liu;
Zhengzhi Cui;
Fang Wang;
Yingpeng Yao;
Guotao Yu;
Jingjing Liu;
Dengchao Cao;
Shuaishuai Niu;
Menghao You;
Zhen Sun;
Di Lian;
Tianyan Zhao;
Youmin Kang;
Yaofeng Zhao;
Hai-Hui Xue;
Shuyang Yu

Publication type:

Article

Works by Hai-Hui Xue

Bystander responses impact accurate detection of murine and human antigen-specific CD8 T cells.

Sepsis leads to lasting changes in phenotype and function of memory CD8 T cells.

Protective function and durability of mouse lymph node-resident memory CD8<sup>+</sup> T cells.

Oncogenic and Tumor Suppressor Functions for Lymphoid Enhancer Factor 1 in E2a<sup>-/-</sup> T Acute Lymphoblastic Leukemia.

Stage-specific epigenetic regulation of CD4 expression by coordinated enhancer elements during T cell development.

GA-binding protein regulates KIS gene expression, cell migration, and cell cycle progression.

β-Catenin is required for the differentiation of iNKT2 and iNKT17 cells that augment IL-25-dependent lung inflammation.

Phenotypic and Functional Alterations in Circulating Memory CD8 T Cells with Time after Primary Infection.

The Timing of Stimulation and IL-2 Signaling Regulate Secondary CD8 T Cell Responses.

Fidelity of a BAC-EGFP transgene in reporting dynamic expression of IL-7Rα in T cells.

Ezh2 programs T<sub>FH</sub> differentiation by integrating phosphorylation-dependent activation of Bcl6 and polycomb-dependent repression of p19Arf.

Polymicrobial sepsis influences NK-cell-mediated immunity by diminishing NK-cell-intrinsic receptor-mediated effector responses to viral ligands or infections.

Store Depletion by Caffeine/Ryanodine Activates Capacitative Ca2+ Entry in Nonexcitable A549 Cells1.

Regulation of mature T cell responses by the Wnt signaling pathway.

Time and Antigen-Stimulation History Influence Memory CD8 T Cell Bystander Responses.

Serine phosphorylation of Stat5 proteins in lymphocytes stimulated with IL‐2.

Little to no expression of angiotensin‐converting enzyme‐2 on most human peripheral blood immune cells but highly expressed on tissue macrophages.

From inception to output, Tcf1 and Lef1 safeguard development of T cells and innate immune cells.

Lef1-dependent hypothalamic neurogenesis inhibits anxiety.

Critical roles of mTOR Complex 1 and 2 for T follicular helper cell differentiation and germinal center responses.

HSF1 is a driver of leukemia stem cell self-renewal in acute myeloid leukemia.

Polymicrobial sepsis impairs bystander recruitment of effector cells to infected skin despite optimal sensing and alarming function of skin resident memory CD8 T cells.

Targeting the GA Binding Protein β1L Isoform Does Not Perturb Lymphocyte Development and Function.

Interleukin-21 Receptor Gene Induction in Human T Cells Is Mediated by T-Cell Receptor-Induced Sp1 Activity.

TCF-1 upregulation identifies early innate lymphoid progenitors in the bone marrow.

LEF-1 and TCF-1 orchestrate T<sub>FH</sub> differentiation by regulating differentiation circuits upstream of the transcriptional repressor Bcl6.

TCF-1 and LEF-1 act upstream of Th-POK to promote the CD4<sup>+</sup> T cell fate and interact with Runx3 to silence Cd4 in CD8<sup>+</sup> T cells.

GA binding protein regulates interleukin 7 receptora-chain gene expression in T cells.

Targeting Cbx3 /HP1γ Induces LEF-1 and IL-21R to Promote Tumor-Infiltrating CD8 T-Cell Persistence.

Tcf1 and Lef1 provide constant supervision to mature CD8<sup>+</sup> T cell identity and function by organizing genomic architecture.

Lrp5 and Lrp6 are required for maintaining self-renewal and differentiation of hematopoietic stem cells.