Works by Haesler, Robert

Results: 35

Genetic interplay between human longevity and metabolic pathways - a large-scale eQTL study.

Published in:

Aging Cell, 2017, v. 16, n. 4, p. 716, doi. 10.1111/acel.12598

By:

Häsler, Robert;
Venkatesh, Geetha;
Tan, Qihua;
Flachsbart, Friederike;
Sinha, Anupam;
Rosenstiel, Philip;
Lieb, Wolfgang;
Schreiber, Stefan;
Christensen, Kaare;
Christiansen, Lene;
Nebel, Almut

Publication type:

Article

A Cell-Based Assay Reveals Nuclear Translocation of Intracellular Domains Released by SPPL Proteases.

Published in:

Traffic, 2015, v. 16, n. 8, p. 871, doi. 10.1111/tra.12287

By:

Mentrup, Torben;
Häsler, Robert;
Fluhrer, Regina;
Saftig, Paul;
Schröder, Bernd

Publication type:

Article

Increased intestinal permeability and tight junction disruption by altered expression and localization of occludin in a murine graft versus host disease model.

Published in:

2011

By:

Noth, Rainer;
Lange-Grumfeld, Julia;
Stüber, Eckhard;
Kruse, Marie-Luise;
Ellrichmann, Mark;
Häsler, Robert;
Hampe, Jochen;
Bewig, Burkhard;
Rosenstiel, Philip;
Schreiber, Stefan;
Arlt, Alexander

Publication type:

journal article

Dissection of the Inflammatory Bowel Disease Transcriptome Using Genome-Wide cDNA Microarrays.

Published in:

PLoS Medicine, 2005, v. 2, n. 8, p. 771, doi. 10.1371/journal.pmed.0020199

By:

Costello, Christine M.;
Mah, Nancy;
Häsler, Robert;
Rosenstiel, Philip;
Waetzig, Georg H.;
Hahn, Andreas;
Lu, Tim;
Gurbuz, Yesim;
Nikolaus, Susanna;
Albrecht, Mario;
Hampe, Jochen;
Lucius, Ralph;
Klöppel, Günther;
Eickhoff, Holger;
Lehrach, Hans;
Lengauer, Thomas;
Schreiber, Stefan

Publication type:

Article

Crosstalk between microbiome, regulatory T cells and HCA2 orchestrates the inflammatory response in a murine psoriasis model.

Published in:

Frontiers in Immunology, 2023, v. 14, p. 1, doi. 10.3389/fimmu.2023.1038689

By:

Schwarz, Agatha;
Philippsen, Rebecca;
Piticchio, Serena G.;
Hartmann, Jan N.;
Häsler, Robert;
Rose-John, Stefan;
Schwarz, Thomas

Publication type:

Article

Publisher Correction: Identification and characterization of two functional variants in the human longevity gene FOXO3.

Published in:

Nature Communications, 2018, v. 9, n. 1, p. 1, doi. 10.1038/s41467-018-02842-8

By:

Flachsbart, Friederike;
Dose, Janina;
Gentschew, Liljana;
Geismann, Claudia;
Caliebe, Amke;
Knecht, Carolin;
Nygaard, Marianne;
Badarinarayan, Nandini;
ElSharawy, Abdou;
May, Sandra;
Luzius, Anne;
Torres, Guillermo G.;
Jentzsch, Marlene;
Forster, Michael;
Häsler, Robert;
Pallauf, Kathrin;
Lieb, Wolfgang;
Derbois, Céline;
Galan, Pilar;
Drichel, Dmitriy

Publication type:

Article

Identification and characterization of two functional variants in the human longevity gene FOXO3.

Published in:

Nature Communications, 2017, v. 8, n. 1, p. 1, doi. 10.1038/s41467-017-02183-y

By:

Flachsbart, Friederike;
Dose, Janina;
Gentschew, Liljana;
Badarinarayan, Nandini;
May, Sandra;
Luzius, Anne;
Torres, Guillermo G.;
Jentzsch, Marlene;
Forster, Michael;
Häsler, Robert;
Rosenstiel, Philip;
Franke, Andre;
Nebel, Almut;
Till, Andreas;
Krause-Kyora, Ben;
Schreiber, Stefan;
ElSharawy, Abdou;
Drichel, Dmitriy;
Nothnagel, Michael;
Blanché, Hélène

Publication type:

Article

Targeted deletion of von-Hippel-Lindau in the proximal tubule conditions the kidney against early diabetic kidney disease.

Published in:

Cell Death & Disease, 2023, v. 14, n. 8, p. 1, doi. 10.1038/s41419-023-06074-7

By:

Kunke, Madlen;
Knöfler, Hannah;
Dahlke, Eileen;
Zanon Rodriguez, Luis;
Böttner, Martina;
Larionov, Alexey;
Saudenova, Makhabbat;
Ohrenschall, Gerrit M.;
Westermann, Magdalena;
Porubsky, Stefan;
Bernardes, Joana P.;
Häsler, Robert;
Magnin, Jean-Luc;
Koepsell, Hermann;
Jouret, François;
Theilig, Franziska

Publication type:

Article

A combined epigenome- and transcriptome-wide association study of the oral masticatory mucosa assigns CYP1B1 a central role for epithelial health in smokers.

Published in:

Clinical Epigenetics, 2019, v. 11, n. 1, p. N.PAG, doi. 10.1186/s13148-019-0697-y

By:

Richter, Gesa M.;
Kruppa, Jochen;
Munz, Matthias;
Wiehe, Ricarda;
Häsler, Robert;
Franke, Andre;
Martins, Orlando;
Jockel-Schneider, Yvonne;
Bruckmann, Corinna;
Dommisch, Henrik;
Schaefer, Arne S.

Publication type:

Article

Genetic identification and functional validation of FcγRIV as key molecule in autoantibody-induced tissue injury.

Published in:

Journal of Pathology, 2012, v. 228, n. 1, p. 8, doi. 10.1002/path.4023

By:

Kasperkiewicz, Michael;
Nimmerjahn, Falk;
Wende, Sabina;
Hirose, Misa;
Iwata, Hiroaki;
Jonkman, Marcel F;
Samavedam, Unni;
Gupta, Yask;
Möller, Steffen;
Rentz, Ellen;
Hellberg, Lars;
Kalies, Kathrin;
Yu, Xinhua;
Schmidt, Enno;
Häsler, Robert;
Laskay, Tamás;
Westermann, Jürgen;
Köhl, Jörg;
Zillikens, Detlef;
Ludwig, Ralf J

Publication type:

Article

Dissecting genetics of cutaneous miRNA in a mouse model of an autoimmune blistering disease.

Published in:

BMC Genomics, 2016, v. 17, p. 1, doi. 10.1186/s12864-016-2455-2

By:

Gupta, Yask;
Möller, Steffen;
Witte, Mareike;
Belheouane, Meriem;
Sezin, Tanya;
Hirose, Misa;
Vorobyev, Artem;
Niesar, Felix;
Bischof, Julia;
Ludwig, Ralf J.;
Zillikens, Detlef;
Sadik, Christian D.;
Restle, Tobias;
Häsler, Robert;
Baines, John F.;
Ibrahim, Saleh M.

Publication type:

Article

A tissue-specific landscape of sense/antisense transcription in the mouse intestine.

Published in:

BMC Genomics, 2011, v. 12, p. 1, doi. 10.1186/1471-2164-12-305

By:

Klostermeier, Ulrich C;
Barann, Matthias;
Wittig, Michael;
Häsler, Robert;
Franke, Andre;
Gavrilova, Olga;
Kreck, Benjamin;
Sina, Christian;
Schilhabel, Markus B;
Schreiber, Stefan;
Rosenstiel, Philip

Publication type:

Article

DNA methylation QTL analysis identifies new regulators of human longevity.

Published in:

Human Molecular Genetics, 2020, v. 29, n. 7, p. 1154, doi. 10.1093/hmg/ddaa033

By:

Szymczak, Silke;
Dose, Janina;
Torres, Guillermo G.;
Heinsen, Femke-Anouska;
Venkatesh, Geetha;
Datlinger, Paul;
Nygaard, Marianne;
Mengel-From, Jonas;
Flachsbart, Friederike;
Klapper, Wolfram;
Christensen, Kaare;
Lieb, Wolfgang;
Schreiber, Stefan;
Häsler, Robert;
Bock, Christoph;
Franke, Andre;
Nebel, Almut

Publication type:

Article

A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1.

Published in:

Nature Genetics, 2007, v. 39, n. 2, p. 207, doi. 10.1038/ng1954

By:

Hampe, Jochen;
Franke, Andre;
Rosenstiel, Philip;
Till, Andreas;
Teuber, Markus;
Huse, Klaus;
Albrecht, Mario;
Mayr, Gabriele;
De La Vega, Francisco M.;
Briggs, Jason;
Günther, Simone;
Prescott, Natalie J.;
Onnie, Clive M.;
Häsler, Robert;
Sipos, Bence;
Fölsch, Ulrich R.;
Lengauer, Thomas;
Platzer, Matthias;
Mathew, Christopher G.;
Krawczak, Michael

Publication type:

Article

Sarcoidosis is associated with a truncating splice site mutation in BTNL2.

Published in:

Nature Genetics, 2005, v. 37, n. 4, p. 357, doi. 10.1038/ng1519

By:

Valentonyte, Ruta;
Hampe, Jochen;
Huse, Klaus;
Rosenstiel, Philip;
Albrecht, Mario;
Stenzel, Annette;
Nagy, Marion;
Gaede, Karoline I;
Franke, Andre;
Haesler, Robert;
Koch, Andreas;
Lengauer, Thomas;
Seegert, Dirk;
Reiling, Norbert;
Ehlers, Stefan;
Schwinger, Eberhard;
Platzer, Matthias;
Krawczak, Michael;
Müller-Quernheim, Joachim;
Schürmann, Manfred

Publication type:

Article

Effect of mothers' health literacy on early childhood allergy prevention behaviours: results from the KUNO-Kids health study.

Published in:

BMC Public Health, 2024, v. 24, n. 1, p. 1, doi. 10.1186/s12889-024-19906-8

By:

Pawellek, Maja;
Köninger, Angela;
Melter, Michael;
Kabesch, Michael;
Apfelbacher, Christian;
Brandstetter, Susanne;
Ambrosch, Andreas;
Arndt, Petra A.;
Baessler, Andrea;
Berneburg, Mark;
Böse-O'Reilly, Stephan;
Brunner, Romuald;
Malfertheiner, Sara Fill;
Franke, André;
Häsler, Robert;
Häusler, Sebastian;
Heid, Iris;
Heinze, Stefanie;
Högler, Wolfgang;
Kerzel, Sebastian

Publication type:

Article

Downregulation of TRAIL-Receptor 1 Increases TGFβ Type II Receptor Expression and TGFβ Signalling Via MicroRNA-370-3p in Pancreatic Cancer Cells.

Published in:

Cancers, 2018, v. 10, n. 11, p. 399, doi. 10.3390/cancers10110399

By:

Radke, David I.;
Ling, Qi;
Häsler, Robert;
Alp, Gökhan;
Ungefroren, Hendrik;
Trauzold, Anna

Publication type:

Article

Characteristic changes in microbial community composition and expression of innate immune genes in acute appendicitis.

Published in:

Innate Immunity, 2015, v. 21, n. 1, p. 30, doi. 10.1177/1753425913515033

By:

Arlt, Alexander;
Bharti, Richa;
Ilves, Imre;
Häsler, Robert;
Miettinen, Pekka;
Paajanen, Hannu;
Brunke, Gabriele;
Ellrichmann, Mark;
Rehman, Ateequr;
Hauser, Charlotte;
Egberts, Jan-Hendrik;
Ott, Stephan J;
Schreiber, Stefan;
Rosenstiel, Philip;
Herzig, Karl-Heinz

Publication type:

Article

Genome-wide rare copy number variation screening in ulcerative colitis identifies potential susceptibility loci.

Published in:

BMC Medical Genetics, 2016, v. 17, p. 1, doi. 10.1186/s12881-016-0289-z

By:

Reza Saadati, Hamid;
Wittig, Michael;
Helbig, Ingo;
Häsler, Robert;
Anderson, Carl A.;
Mathew, Christopher G.;
Kupcinskas, Limas;
Parkes, Miles;
Hemming Karlsen, Tom;
Rosenstiel, Philip;
Schreiber, Stefan;
Franke, Andre

Publication type:

Article

Tubular IKKβ Deletion Alleviates Acute Ischemic Kidney Injury and Facilitates Tissue Regeneration.

Published in:

International Journal of Molecular Sciences, 2022, v. 23, n. 17, p. 10199, doi. 10.3390/ijms231710199

By:

Dahlke, Eileen;
Engmann, Toni;
Anan, Yaman;
Häsler, Robert;
Solinas, Giovanni;
Theilig, Franziska

Publication type:

Article

Analysis of intestinal microbiota in hybrid house mice reveals evolutionary divergence in a vertebrate hologenome.

Published in:

Nature Communications, 2015, v. 6, n. 3, p. 6440, doi. 10.1038/ncomms7440

By:

Wang, Jun;
Kalyan, Shirin;
Steck, Natalie;
Turner, Leslie M.;
Harr, Bettina;
Künzel, Sven;
Vallier, Marie;
Häsler, Robert;
Franke, Andre;
Oberg, Hans-Heinrich;
Ibrahim, Saleh M.;
Grassl, Guntram A.;
Kabelitz, Dieter;
Baines, John F.

Publication type:

Article

CD79a promotes CNS-infiltration and leukemia engraftment in pediatric B-cell precursor acute lymphoblastic leukemia.

Published in:

Communications Biology, 2021, v. 4, n. 1, p. 1, doi. 10.1038/s42003-020-01591-z

By:

Lenk, Lennart;
Carlet, Michela;
Vogiatzi, Fotini;
Spory, Lea;
Winterberg, Dorothee;
Cousins, Antony;
Vossen-Gajcy, Michaela;
Ibruli, Olta;
Vokuhl, Christian;
Cario, Gunnar;
El Ayoubi, Omar;
Kramer, Lisa;
Ritgen, Matthias;
Brüggemann, Monika;
Häsler, Robert;
Schrappe, Martin;
Fuhrmann, Stephan;
Halsey, Christina;
Jeremias, Irmela;
Hobeika, Elias

Publication type:

Article

Kenntnisse und tatsächliche Umsetzung der Empfehlungen zur Prävention des plötzlichen Säuglingstods innerhalb des ersten Lebensjahres – eine Analyse longitudinaler Daten der KUNO Kids Gesundheitsstudie.

Published in:

Somnologie, 2024, v. 28, n. 2, p. 88, doi. 10.1007/s11818-024-00469-0

By:

Seebauer, Ludwig M.;
Gaertner, Vincent D.;
Fill Malfertheiner, Sara;
Postpischil, Janina;
Brandstetter, Susanne;
Seelbach-Göbel, Birgit;
Apfelbacher, Christian;
Melter, Michael;
Kabesch, Michael;
Kerzel, Sebastian;
Ambrosch, Andreas;
Arndt, Petra A.;
Baessler, Andrea;
Berneburg, Mark;
Böse-O'Reilly, Stephan;
Brunner, Romuald;
Franke, André;
Häsler, Robert;
Häusler, Sebastian;
Heid, Iris

Publication type:

Article

The large non-coding RNA ANRIL, which is associated with atherosclerosis, periodontitis and several forms of cancer, regulates ADIPOR1, VAMP3 and C11ORF10.

Published in:

Human Molecular Genetics, 2013, v. 22, n. 22, p. 4516, doi. 10.1093/hmg/ddt299

By:

Bochenek, Gregor;
Häsler, Robert;
El Mokhtari, Nour-Eddine;
König, Inke R.;
Loos, Bruno G.;
Jepsen, Soeren;
Rosenstiel, Philip;
Schreiber, Stefan;
Schaefer, Arne S.

Publication type:

Article

Disease-Associated miRNA-mRNA Networks in Oral Lichen Planus

Published in:

PLoS ONE, 2013, v. 8, n. 5, p. 1, doi. 10.1371/journal.pone.0063015

By:

Gassling, Volker;
Hampe, Jochen;
Açil, Yahya;
Braesen, Jan Hinrich;
Wiltfang, Jörg;
Häsler, Robert

Publication type:

Article

Microbial Pattern Recognition Causes Distinct Functional Micro-RNA Signatures in Primary Human Monocytes.

Published in:

PLoS ONE, 2012, v. 7, n. 2, p. 1, doi. 10.1371/journal.pone.0031151

By:

Häsler, Robert;
Jacobs, Gunnar;
Till, Andreas;
Grabe, Nils;
Cordes, Christian;
Nikolaus, Susanna;
Lao, Kaiqin;
Schreiber, Stefan;
Rosenstiel, Philip

Publication type:

Article

DNA methyltransferase 3A controls intestinal epithelial barrier function and regeneration in the colon.

Published in:

Nature Communications, 2022, v. 13, n. 1, p. 1, doi. 10.1038/s41467-022-33844-2

By:

Fazio, Antonella;
Bordoni, Dora;
Kuiper, Jan W. P.;
Weber-Stiehl, Saskia;
Stengel, Stephanie T.;
Arnold, Philipp;
Ellinghaus, David;
Ito, Go;
Tran, Florian;
Messner, Berith;
Henning, Anna;
Bernardes, Joana P.;
Häsler, Robert;
Luzius, Anne;
Imm, Simon;
Hinrichsen, Finn;
Franke, Andre;
Huber, Samuel;
Nikolaus, Susanna;
Aden, Konrad

Publication type:

Article

Peri-Implantitis versus Periodontitis: Functional Differences Indicated by Transcriptome Profiling.

Published in:

Clinical Implant Dentistry & Related Research, 2014, v. 16, n. 3, p. 401, doi. 10.1111/cid.12001

By:

Becker, Stephan T.;
Beck‐Broichsitter, Benedicta E.;
Graetz, Christian;
Dörfer, Christof E.;
Wiltfang, Jörg;
Häsler, Robert

Publication type:

Article

Genome-wide association study for ulcerative colitis identifies risk loci at 7q22 and 22q13 (IL17REL).

Published in:

Nature Genetics, 2010, v. 42, n. 4, p. 292, doi. 10.1038/ng.553

By:

Franke, Andre;
Balschun, Tobias;
Sina, Christian;
Ellinghaus, David;
Häsler, Robert;
Mayr, Gabriele;
Albrecht, Mario;
Wittig, Michael;
Buchert, Eva;
Nikolaus, Susanna;
Gieger, Christian;
Wichmann, H. Erich;
Sventoraityte, Jurgita;
Kupcinskas, Limas;
Onnie, Clive M.;
Gazouli, Maria;
Anagnou, Nicholas P.;
Strachan, David;
McArdle, Wendy L.;
Mathew, Christopher G.

Publication type:

Article

A tissue-specific landscape of sense/antisense transcription in the mouse intestine.

Published in:

BMC Genomics, 2011, v. 12, n. 1, p. 305, doi. 10.1186/1471-2164-12-305

By:

Klostermeier, Ulrich C.;
Barann, Matthias;
Wittig, Michael;
Häsler, Robert;
Franke, Andre;
Gavrilova, Olga;
Kreck, Benjamin;
Sina, Christian;
Schilhabel, Markus B.;
Schreiber, Stefan;
Rosenstiel, Philip

Publication type:

Article

The antibiotic resistome and microbiota landscape of refugees from Syria, Iraq and Afghanistan in Germany.

Published in:

Microbiome, 2018, v. 6, p. 1, doi. 10.1186/s40168-018-0414-7

By:

Häsler, Robert;
Kautz, Christian;
Rehman, Ateequr;
Podschun, Rainer;
Gassling, Volker;
Brzoska, Pius;
Sherlock, Jon;
Gräsner, Jan-Thorsten;
Hoppenstedt, Gesine;
Schubert, Sabine;
Ferlinz, Astrid;
Lieb, Wolfgang;
Laudes, Matthias;
Heinsen, Femke-Anouska;
Scholz, Jens;
Harmsen, Dag;
Franke, Andre;
Eisend, Swantje;
Kunze, Thomas;
Fickenscher, Helmut

Publication type:

Article

Dupilumab but not cyclosporine treatment shifts the microbiome toward a healthy skin flora in patients with moderate‐to‐severe atopic dermatitis.

Published in:

Allergy, 2023, v. 78, n. 8, p. 2290, doi. 10.1111/all.15742

By:

Hartmann, Jan;
Moitinho‐Silva, Lucas;
Sander, Nicole;
Harder, Inken;
Häsler, Robert;
Rodriguez, Elke;
Haufe, Eva;
Kleinheinz, Andreas;
Abraham, Susanne;
Heratizadeh, Annice;
Weisshaar, Elke;
Schäkel, Knut;
Handrick, Christiane;
Augustin, Matthias;
Wollenberg, Andreas;
Staubach‐Renz, Petra;
Ertner, Konstantin;
Sticherling, Michael;
Schwarz, Beate;
Quist, Sven

Publication type:

Article

Tethering soluble meprin α in an enzyme complex to the cell surface affects IBD-associated genes.

Published in:

FASEB Journal, 2019, v. 33, n. 6, p. 7490, doi. 10.1096/fj.201802391R

By:

Peters, Florian;
Scharfenberg, Franka;
Colmorgen, Cynthia;
Armbrust, Fred;
Wichert, Rielana;
Arnold, Philipp;
Potempa, Barbara;
Potempa, Jan;
Pietrzik, Claus U.;
Häsler, Robert;
Rosenstiel, Philip;
Becker-Pauly, Christoph

Publication type:

Article

Can Zipf's law be adapted to normalize microarrays?

Published in:

BMC Bioinformatics, 2005, v. 6, p. 37, doi. 10.1186/1471-2105-6-37

By:

Lu, Tim;
Costello, Christine M.;
Peter J. P. Croucher;
Häsler, Robert;
Deuschl, Gunther;
Schreiber, Stefan

Publication type:

Article

NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer.

Published in:

Journal of Clinical Investigation, 2013, v. 123, n. 2, p. 700, doi. 10.1172/JCI62236

By:

Couturier-Maillard, Aurélie;
Secher, Thomas;
Rehman, Ateequr;
Normand, Sylvain;
Arcangelis, Adèle De;
Haesler, Robert;
Huot, Ludovic;
Grandjean, Teddy;
Bressenot, Aude;
Delanoye-Crespin, Anne;
Gaillot, Olivier;
Schreiber, Stefan;
Lemoine, Yves;
Ryffe, Bernhard;
Hot, David;
Nùñez, Gabriel;
Chen, Grace;
Rosenstie, Philip;
Chamaillard, Mathias

Publication type:

Article