Works matching AU Hackett, Tillie L.

Results: 24

Angiotensin-Converting Enzyme 2 (ACE2), Transmembrane Peptidase Serine 2 (TMPRSS2), and Furin Expression Increases in the Lungs of Patients with Idiopathic Pulmonary Fibrosis (IPF) and Lymphangioleiomyomatosis (LAM): Implications for SARS-CoV-2 (COVID-19) Infections

Published in:

Journal of Clinical Medicine, 2022, v. 11, n. 3, p. 777, doi. 10.3390/jcm11030777

By:

Lu, Wenying;
Eapen, Mathew Suji;
Singhera, Gurpreet Kaur;
Markos, James;
Haug, Greg;
Chia, Collin;
Larby, Josie;
Brake, Samuel James;
Westall, Glen P.;
Jaffar, Jade;
Kalidhindi, Rama Satyanarayana Raju;
Fonseka, Nimesha De;
Sathish, Venkatachalem;
Hackett, Tillie L.;
Sohal, Sukhwinder Singh

Publication type:

Article

Transforming growth factor-β1 and SMAD signalling pathway in the small airways of smokers and patients with COPD: potential role in driving fibrotic type-2 epithelial mesenchymal transition.

Published in:

Frontiers in Immunology, 2023, p. 1, doi. 10.3389/fimmu.2023.1216506

By:

Brake, Samuel James;
Wenying Lu;
Chia, Collin;
Haug, Greg;
Larby, Josie;
Hardikar, Ashutosh;
Singhera, Gurpreet K.;
Hackett, Tillie L.;
Eapen, Mathew Suji;
Sohal, Sukhwinder Singh

Publication type:

Article

Oxidized Phosphatidylcholines Trigger TRPA1 and Ryanodine Receptor-dependent Airway Smooth Muscle Contraction.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2023, v. 69, n. 6, p. 649, doi. 10.1165/rcmb.2022-0457OC

By:

Vaghasiya, Jignesh;
Dalvand, Azadeh;
Sikarwar, Anurag;
Mangat, Divleen;
Ragheb, Mirna;
Kowatsch, Katarina;
Pandey, Dheerendra;
Hosseini, Seyed Mojtaba;
Hackett, Tillie L.;
Karimi-Abdolrezaee, Soheila;
Ravandi, Amir;
Pascoe, Christopher D.;
Halayko, Andrew J.

Publication type:

Article

Ultrastructure of Human Tracheal Smooth Muscle from Subjects with Asthma and Nonasthmatic Subjects: Standardized Methods for Comparison.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2015, v. 52, n. 3, p. 304, doi. 10.1165/rcmb.2014-0176OC

By:

Syyong, Harley T.;
Pascoe, Chris D.;
Zhang, Jenny;
Arsenault, Bryna A.;
Solomon, Dennis;
Elliott, W. Mark;
Hackett, Tillie L.;
Walker, David C.;
Paré, Peter D.;
Seow, Chun Y.

Publication type:

Article

Ultrastructure of human tracheal smooth muscle from asthmatic and non-asthmatic subjects: Standardized methods for comparison.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2015, v. 52, n. 3, p. E1, doi. 10.1165/rcmb.2014-0176oc

By:

Syyong, Harley T.;
Pascoe, Chris D.;
Zhang, Jenny;
Arsenault, Bryna A.;
Solomon, Dennis;
Elliott, W. Mark;
Hackett, Tillie L.;
Walker, David C.;
Pare, Peter D.;
Seow, Chun Y.

Publication type:

Article

Human Lung Parenchyma but Not Proximal Bronchi Produces Fibroblasts with Enhanced TGF-β Signaling and α-SMA Expression.

Published in:

American Journal of Respiratory Cell & Molecular Biology, 2010, v. 43, n. 6, p. 641, doi. 10.1165/rcmb.2009-0318OC

By:

Pechkovsky, Dmitri V.;
Hackett, Tillie L.;
An, Steven S.;
Shaheen, Furquan;
Murray, Lynne A.;
Knight, Darryl A.

Publication type:

Article

Second harmonic generation imaging of collagen scaffolds within the alveolar ducts of healthy and emphysematous mouse lungs.

Published in:

Histochemistry & Cell Biology, 2021, v. 155, n. 2, p. 279, doi. 10.1007/s00418-020-01959-6

By:

Mostaco-Guidolin, Leila B.;
Loube, Jeffrey;
Barlow, Aaron;
Osei, Emmanuel T.;
Vasilescu, Dragoș M.;
Hsieh, Aileen;
Fouadi, May;
Young, Christine;
Scott, Alan L.;
Mitzner, Wayne;
Hackett, Tillie L.

Publication type:

Article

Hedgehog Signaling as a Therapeutic Target for Airway Remodeling and Inflammation in Allergic Asthma.

Published in:

Cells (2073-4409), 2022, v. 11, n. 19, p. 3016, doi. 10.3390/cells11193016

By:

Tam, Anthony;
Osei, Emmanuel Twumasi;
Cheung, Chung Y.;
Hughes, Michael;
Yang, Chen X.;
McNagny, Kelly M.;
Dorscheid, Delbert R.;
Singhera, Gurpreet K.;
Hallstrand, Teal S.;
Warner, Stephanie;
Hogg, James C.;
Hackett, Tillie L.;
Lim, Chinten J.;
Sin, Don D.

Publication type:

Article

Noninvasive Imaging Biomarker Identifies Small Airway Damage in Severe Chronic Obstructive Pulmonary Disease.

Published in:

2019

By:

Vasilescu, Dragoş M.;
Martinez, Fernando J.;
Marchetti, Nathaniel;
Galbán, Craig J.;
Hatt, Charles;
Meldrum, Catherine A.;
Dass, Chandra;
Tanabe, Naoya;
Reddy, Rishindra M.;
Lagstein, Amir;
Ross, Brian D.;
Labaki, Wassim W.;
Murray, Susan;
Xia Meng;
Curtis, Jeffrey L.;
Hackett, Tillie L.;
Kazerooni, Ella A.;
Criner, Gerard J.;
Hogg, James C.;
Han, MeiLan K.

Publication type:

journal article

IL-4Rα blockade reduces influenza-associated morbidity in a murine model of allergic asthma.

Published in:

2021

By:

Shahangian, Kimia;
Ngan, David A.;
Chen, H. H. Rachel;
Oh, Yeni;
Tam, Anthony;
Wen, Jing;
Cheung, Chung;
Knight, Darryl A.;
Dorscheid, Delbert R.;
Hackett, Tillie L.;
Hughes, Michael R.;
McNagny, Kelly M.;
Hirota, Jeremy A.;
Niikura, Masahiro;
Man, S. F. Paul;
Sin, Don D.

Publication type:

journal article

Lung eQTLs to Help Reveal the Molecular Underpinnings of Asthma.

Published in:

PLoS Genetics, 2012, v. 8, n. 1, p. 1, doi. 10.1371/journal.pgen.1003029

By:

Ke Hao;
Bossé, Yohan;
Nickle, David C.;
Paré, Peter D.;
Postma, Dirkje S.;
Laviolette, Michel;
Sandford, Andrew;
Hackett, Tillie L.;
Daley, Denise;
Hogg, James C.;
Elliott, W. Mark;
Couture, Christian;
Lamontagne, Maxime;
Brandsma, Corry-Anke;
van den Berge, Maarten;
Koppelman, Gerard;
Reicin, Alise S.;
Nicholson, Donald W.;
Malkov, Vladislav;
Derry, Jonathan M.

Publication type:

Article

Gene expression analysis in asthma using a targeted multiplex array.

Published in:

2017

By:

Pascoe, Christopher D.;
Obeidat, Ma'en;
Arsenault, Bryna A.;
Nie, Yunlong;
Warner, Stephanie;
Stefanowicz, Dorota;
Wadsworth, Samuel J.;
Hirota, Jeremy A.;
Yang, S. Jasemine;
Dorscheid, Delbert R.;
Carlsten, Chris;
Hackett, Tillie L.;
Seow, Chun Y.;
Paré, Peter D.;
Jasemine Yang, S

Publication type:

journal article

Morphometric analysis of inflammation in bronchial biopsies following exposure to inhaled diesel exhaust and allergen challenge in atopic subjects.

Published in:

Particle & Fibre Toxicology, 2016, v. 13, p. 1, doi. 10.1186/s12989-016-0114-z

By:

Hosseini, Ali;
Hirota, Jeremy A.;
Hackett, Tillie L.;
McNagny, Kelly M.;
Wilson, Susan J.;
Carlsten, Chris

Publication type:

Article

A gene expression signature of emphysemarelated lung destruction and its reversal by the tripeptide GHK.

Published in:

Genome Medicine, 2012, v. 4, n. 8, p. 1, doi. 10.1186/gm367

By:

Campbell, Joshua D;
McDonough, John E;
Zeskind, Julie E;
Hackett, Tillie L;
Pechkovsky, Dmitri V;
Brandsma, Corry-Anke;
Suzuki, Masaru;
Gosselink, John V;
Liu, Gang;
Alekseyev, Yuriy O;
Ji Xiao;
Xiaohui Zhang;
Hayashi, Shizu;
Cooper, Joel D;
Timens, Wim;
Postma, Dirkje S;
Knight, Darryl A;
Marc, Lenburg E;
James, Hogg C;
Avrum, Spira

Publication type:

Article

SARS-CoV-2 (COVID-19) Adhesion Site Protein Upregulation in Small Airways, Type 2 Pneumocytes, and Alveolar Macrophages of Smokers and COPD – Possible Implications for Interstitial Fibrosis.

Published in:

International Journal of COPD, 2022, v. 17, p. 101, doi. 10.2147/COPD.S329783

By:

Brake, Samuel James;
Eapen, Mathew Suji;
McAlinden, Kielan Darcy;
Markos, James;
Haug, Greg;
Larby, Josie;
Chia, Collin;
Hardikar, Ashutosh;
Singhera, Gurpreet Kaur;
Hackett, Tillie L;
Lu, Wenying;
Sohal, Sukhwinder Singh

Publication type:

Article

Potential role of stem cells in management of COPD.

Published in:

International Journal of COPD, 2010, v. 5, p. 81

By:

Hackett, Tillie L.;
Knight, Darryl A.;
Sin, Don D.

Publication type:

Article

Granzyme B Cleaves Decorin, Biglycan and Soluble Betaglycan, Releasing Active Transforming Growth Factor-β1.

Published in:

PLoS ONE, 2012, v. 7, n. 3, p. 1, doi. 10.1371/journal.pone.0033163

By:

Boivin, Wendy A.;
Shackleford, Marlo;
Vanden Hoek, Amanda;
Zhao, Hongyan;
Hackett, Tillie L.;
Knight, Darryl A.;
Granville, David J.

Publication type:

Article

Granzyme K Activates Protease-Activated Receptor-1.

Published in:

PLoS ONE, 2011, v. 6, n. 6, p. 1, doi. 10.1371/journal.pone.0021484

By:

Cooper, Dawn M.;
Pechkovsky, Dmitri V.;
Hackett, Tillie L.;
Knight, Darryl A.;
Granville, David J.

Publication type:

Article

Dual Organism Transcriptomics of Airway Epithelial Cells Interacting with Conidia of Aspergillus fumigatus.

Published in:

PLoS ONE, 2011, v. 6, n. 5, p. 1, doi. 10.1371/journal.pone.0020527

By:

Oosthuizen, Jean L.;
Gomez, Pol;
Ruan, Jian;
Hackett, Tillie L.;
Moore, Margo M.;
Knight, Darryl A.;
Tebbutt, Scott J.

Publication type:

Article

BMP-7 Does Not Protect against Bleomycin-Induced Lung or Skin Fibrosis.

Published in:

PLoS ONE, 2008, v. 3, n. 12, p. 1, doi. 10.1371/journal.pone.0004039

By:

Murray, Lynne A.;
Hackett, Tillie L.;
Warner, Stephanie M.;
Shaheen, Furquan;
Argentieri, Rochelle L.;
Dudas, Paul;
Farrell, Francis X.;
Knight, Darryl A.

Publication type:

Article

Oxidative modification of albumin in the parenchymal lung tissue of current smokers with chronic obstructive pulmonary disease.

Published in:

Respiratory Research, 2010, v. 11, p. 180, doi. 10.1186/1465-9921-11-180

By:

Hackett, Tillie L.;
Scarci, Marco;
Lu Zheng;
Wan Tan;
Treasure, Tom;
Warner, Jane A.

Publication type:

Article

Epithelial–mesenchymal transition changes in nonsmall cell lung cancer patients with early COPD.

Published in:

ERJ Open Research, 2023, v. 9, n. 6, p. 1, doi. 10.1183/23120541.00581-2023

By:

Wenying Lu;
Suji Eapen, Mathew;
Hardikar, Ashutosh;
Chia, Collin;
Robertson, Iain;
Singhera, Gurpreet Kaur;
Hackett, Tillie L.;
Sohal, Sukhwinder Singh

Publication type:

Article

Acute cigarette smoke exposure activates apoptotic and inflammatory programs but a second stimulus is required to induce epithelial to mesenchymal transition in COPD epithelium.

Published in:

2017

By:

Murray, Lynne A.;
Dunmore, Rebecca;
Camelo, Ana;
Da Silva, Carla A.;
Gustavsson, Malin J.;
Habiel, David M.;
Hackett, Tillie L.;
Hogaboam, Cory M.;
Sleeman, Matthew A.;
Knight, Darryl A.

Publication type:

journal article

Functional genomics of human bronchial epithelialcells directly interacting with conidia of Aspergillusfumigatus.

Published in:

BMC Genomics, 2010, v. 11, p. 358, doi. 10.1186/1471-2164-11-358

By:

Gomez, Pol;
Hackett, Tillie L.;
Moore, Margo M.;
Knight, Darryl A.;
Tebbutt, Scott J.

Publication type:

Article